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1. Full Text Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts
by Takahashi, Masamichi and Miki, Shunichiro and Fujimoto, Kenji and Fukuoka, Kohei and Matsushita, Yuko and Maida, Yoshiko and Yasukawa, Mami and Hayashi, Mitsuhiro and Shinkyo, Raku and Kikuchi, Kiyomi and Mukasa, Akitake and Nishikawa, Ryo and Tamura, Kenji and Narita, Yoshitaka and Hamada, Akinobu and Masutomi, Kenkichi and Ichimura, Koichi
Cancer science, ISSN 1347-9032, 07/2019, Volume 110, Issue 7, pp. 2247 - 2257
mass spectrometry imaging | glioblastoma | TERT | RdRP | eribulin | Life Sciences & Biomedicine | Oncology | Science & Technology | Brain - diagnostic imaging | Brain Neoplasms - diagnostic imaging | Furans - pharmacology | Humans | Promoter Regions, Genetic - drug effects | Brain - metabolism | Glioblastoma - diagnostic imaging | Telomerase - genetics | Glioblastoma - genetics | Female | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Ketones - pharmacology | Injections, Intraperitoneal | Brain Neoplasms - genetics | Ketones - administration & dosage | Treatment Outcome | Drug Repositioning | Brain Neoplasms - drug therapy | Brain - drug effects | Xenograft Model Antitumor Assays | Animals | Cell Line, Tumor | Mice | Glioblastoma - drug therapy | Furans - administration & dosage | Brain | Glioblastoma multiforme | Mass spectrometry | Drug approval | Telomerase | Brain tumors | Neuroimaging | Senescence | Intravenous administration | Telomerase reverse transcriptase | RNA-directed DNA polymerase | Brain cancer | Glioblastoma | Clinical trials | Cancer therapies | DNA-directed RNA polymerase | Experiments | Cell growth | Xenografts | Medical research | Kidneys | Research funding | Cell division | Mass spectroscopy | Breast cancer | RNA polymerase | Injection | Patients | Studies | Brain research | Biomarkers | Glioblastoma cells | Mutation | Pharmacokinetics | Binding sites | Tumors | Index Medicus | Original
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2. Full Text Cigarette Smoke Extract Disrupts Transcriptional Activities Mediated by Thyroid Hormones and Its Receptors
by Hayashi, Misa and Futawaka, Kumi and Matsushita, Midori and Hatai, Mayuko and Yoshikawa, Noriko and Nakamura, Kazuki and Tagami, Tetsuya and Moriyama, Kenji and National Hospital Organization and aDepartment of Medicine and Clinical Science and Graduate School of Pharmaceutical Sciences and Clinical Research Institute and Metabolism and Hypertension and Kyoto Medical Center and and (bDivision of Endocrinology and Mukogawa Women's University
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 3, pp. 383 - 393
signal transduction | endocrine disruptor | thyroid hormone receptor | Signal transduction | Thyroid hormone receptor | Endocrine disruptor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Receptors, Thyroid Hormone - drug effects | Transcription, Genetic - drug effects | Thyroid Hormones - pharmacology | Smoke - adverse effects | Humans | Carrier Proteins - drug effects | Nerve Tissue Proteins - drug effects | Thyroid Hormone Receptors alpha - drug effects | Thyroid Hormone Receptors beta - genetics | Gene Expression Regulation - drug effects | Nuclear Receptor Coactivator 1 - genetics | Receptors, Thyroid Hormone - genetics | Thyroid Hormone Receptors alpha - genetics | Thyroid Hormone Receptors beta - drug effects | HEK293 Cells | Smoke - analysis | Tobacco - chemistry | Tobacco - adverse effects | Malate Dehydrogenase - biosynthesis | Endocrine disruptors | Carbonyl compounds | Physiological effects | Tobacco smoke | Transcription | Glucocorticoids | Thyroid hormone receptors | Thyroid gland | Smoke | Hormones | Gene expression | Cigarettes | Cofactors | Acrolein | Receptors | Toxicants | Steroid receptor coactivator 1 | GRIP1 protein | Physiology | Thyroid hormones | Cigarette smoke | Steroids | Carbonyls | Thyroid | Index Medicus
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3. Full Text Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus
by Hayami, Hiroshi and Takahashi, Satoshi and Ishikawa, Kiyohito and Yasuda, Mitsuru and Yamamoto, Shingo and Wada, Koichiro and Kobayashi, Kanao and Hamasuna, Ryoichi and Minamitani, Shinichi and Matsumoto, Tetsuya and Kiyota, Hiroshi and Tateda, Kazuhiro and Sato, Junko and Hanaki, Hideaki and Masumori, Naoya and Nishiyama, Hiroyuki and Miyazaki, Jun and Fujimoto, Kiyohide and Tanaka, Kazushi and Uehara, Shinya and Matsubara, Akio and Ito, Kenji and Hayashi, Kenji and Kurimura, Yuichiro and Ito, Shin and Takeuchi, Toshimi and Narita, Harunori and Izumitani, Masanobu and Nishimura, Hirofumi and Kawahara, Motoshi and Hara, Makoto and Hosobe, Takahide and Takashima, Kenji and Chokyu, Hirofumi and Matsumura, Masaru and Ihara, Hideari and Uno, Satoshi and Monden, Koichi and Sumii, Toru and Kawai, Shuichi and Kariya, Satoru and Sato, Takashi and Yoshioka, Masaru and Kadena, Hitoshi and Matsushita, Shinji and Nishi, Shohei and Hosokawa, Yukinari and Shirane, Takeshi and Yoh, Mutsumasa and Watanabe, Syuji and Makinose, Shinichi and Uemura, Tetsuji and Goto, Hirokazu
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, ISSN 1341-321X, 06/2019, Volume 25, Issue 6, pp. 413 - 422
Resistance | Acute uncomplicated cystitis | Surveillance | Susceptibility | Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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4. Full Text Palivizumab prophylaxis in preterm infants and subsequent recurrent wheezing: Six-year follow-up study
by Mochizuki, Hiroyuki and Kusuda, Satoshi and Okada, Kenji and Yoshihara, Shigemi and Furuya, Hiroyuki and Simões, Eric A.F and Asanuma, Hideomi and Yoshida, Hiroshi and Katayose, Masahiko and Imamura, Takashi and Suzumura, Hiroshi and Honma, Youko and Maruyama, Kenichi and Ohki, Yasushi and Ozasa, Koji and Nariai, Akiyoshi and Uchiyama, Atsushi and Uryu, Hideko and Hosono, Shigeharu and Kondo, Masatoshi and Kawase, Yasuharu and Ikeda, Kazunari and Naito, Atsushi and Minami, Yuki and Nakamura, Tomohiko and Baba, Atsushi and Nagayama, Yoshihisa and Kaneda, Hisashi and Ohki, Shigeru and Shirai, Masami and Henmi, Yuto and Suzuki, Chizuko and Ieda, Kuniko and Tanaka, Taihei and Kono, Yoshinori and Nisizawa, Kashiro and Niwa, Fusako and Ito, Hisato and Tokunaga, Yasuyuki and Takada, Yoshinobu and Nishikawa, Yoshihide and Nagata, Ikuo and Kajino, Yasuhisa and Watabe, Shinichi and Yoshio, Hiroyuki and Takahashi, Nobumasa and Sasaki, Nobutaka and Hayashidani, Michiko and Tateishi, Hiroshi and Matsushita, Kenji and Nakamura, Masatoshi and Nakayama, Hideki and Yamamoto, Go and Kanemitsu, Noriaki and Takayanagi, Toshimitsu and Sato, Ayumi and Ibara, Satoshi and Sci Comm Elucidation Infantile and Scientific Committee for Elucidation of Infantile Asthma
American journal of respiratory and critical care medicine, ISSN 1073-449X, 07/2017, Volume 196, Issue 1, pp. 29 - 38
Palivizumab | Respiratory syncytial virus | Monoclonal antibody | Respiratory infectious diseases | Asthma | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Recurrence | Prospective Studies | Asthma - prevention & control | Follow-Up Studies | Antiviral Agents - therapeutic use | Respiratory Syncytial Viruses - drug effects | Humans | Palivizumab - therapeutic use | Child, Preschool | Infant | Male | Treatment Outcome | Case-Control Studies | Infant, Premature | Respiratory Syncytial Virus Infections - prevention & control | Female | Respiratory Sounds - drug effects | Child | Food allergies | Parents & parenting | Newborn babies | Cellular telephones | Physicians | Infections | Health risk assessment | Viral infections | Age | Index Medicus | Abridged Index Medicus
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5. Rediscovering America
: Japanese perspectives on the American century
by Duus, Peter and Hasegawa, Kenji
2011, 1, Twentieth-century Japan : the emergence of a world power, ISBN 0520268458, Volume 19, xi, 341
Public opinion | Civilization | 20th century | United States | Foreign public opinion, Japanese | Japan | Relations | History | HISTORY
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6. Full Text The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling
by Amano, Wataru, DVM and Nakajima, Saeko, MD, PhD and Kunugi, Hayato, PhD and Numata, Yasuharu, MS and Kitoh, Akihiko, MD, PhD and Egawa, Gyohei, MD, PhD and Dainichi, Teruki, MD, PhD and Honda, Tetsuya, MD, PhD and Otsuka, Atsushi, MD, PhD and Kimoto, Yukari, MS and Yamamoto, Yasuo, MS and Tanimoto, Atsuo, MS and Matsushita, Mutsuyoshi, PhD and Miyachi, Yoshiki, MD, PhD and Kabashima, Kenji, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 667 - 677.e7
Allergy and Immunology | keratinocyte differentiation | signal transducer and activator of transcription 3 | Atopic dermatitis | filaggrin | Janus kinase inhibitor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | RNA, Small Interfering - genetics | Dermatitis, Atopic - genetics | Humans | Interleukin-13 - immunology | Transplantation, Heterologous | STAT6 Transcription Factor - genetics | Interleukin-13 - genetics | RNA, Small Interfering - immunology | Skin, Artificial | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Skin Transplantation | STAT6 Transcription Factor - antagonists & inhibitors | Interleukin-4 - genetics | STAT3 Transcription Factor - genetics | Disease Models, Animal | Intermediate Filament Proteins - immunology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Dermatitis, Atopic - pathology | STAT6 Transcription Factor - immunology | Keratinocytes - immunology | Interleukin-4 - immunology | Keratinocytes - pathology | Animals | Dermatitis, Atopic - drug therapy | Keratinocytes - drug effects | Cell Differentiation - drug effects | Mice, Nude | Mice | Protein Kinase Inhibitors - pharmacology | Immunocompromised Host | STAT3 Transcription Factor - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Circuit components | Allergens | Mutual fund industry | Skin | Genetic transcription | Proteins | Cytokines | Genes | Skin & tissue grafts | Ligands | Kinases | Potassium | Chemokines | Index Medicus | Abridged Index Medicus
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7. Full Text A critical role of IL-33 in experimental allergic rhinitis
by Haenuki, Yoko, MD and Matsushita, Kazufumi, PhD and Futatsugi-Yumikura, Shizue, BPharm and Ishii, Ken J., MD, PhD and Kawagoe, Tatsukata, MD, PhD and Imoto, Yoshimasa, MD, PhD and Fujieda, Shigeharu, MD, PhD and Yasuda, Makoto, MD, PhD and Hisa, Yasuo, MD, PhD and Akira, Shizuo, MD, PhD and Nakanishi, Kenji, MD, PhD and Yoshimoto, Tomohiro, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2012, Volume 130, Issue 1, pp. 184 - 194.e11
Allergy and Immunology | sneezing | ragweed pollen | epithelial cells | eosinophils | allergic rhinitis | basophils | mast cells | IL-33 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Otorhinolaryngology. Stomatology | Non tumoral diseases | Biological and medical sciences | Medical sciences | Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology | Rhinitis - immunology | Humans | Mice, Inbred C57BL | Ambrosia - immunology | Nasal Mucosa - pathology | Pollen - immunology | Eosinophils - immunology | Interleukins - metabolism | Hypersensitivity, Immediate - pathology | Mice, Knockout | Nasal Provocation Tests | Interleukins - genetics | Animals | Nasal Mucosa - immunology | Basophils - immunology | Hypersensitivity, Immediate - immunology | Mice | Mice, Inbred BALB C | Disease Models, Animal | Medical colleges | Rhinitis | Proteases | Fluorescein | Albumin | Universities and colleges | Macrophages | Proteins | Gene expression | Allergies | Colleges & universities | Index Medicus | Abridged Index Medicus
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8. Full Text Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study
by Nakashima, Misako and Iohara, Koichiro and Murakami, Masashi and Nakamura, Hiroshi and Sato, Yayoi and Ariji, Yoshiko and Matsushita, Kenji
Stem cell research & therapy, ISSN 1757-6512, 03/2017, Volume 8, Issue 1, pp. 61 - 61
Good manufacturing practice (GMP) | Granulocyte colony-stimulating factor (G-CSF) | Autologous cell transplantation | Pulp regeneration | Pulpectomy | Mobilized dental pulp stem cells (Mobilized DPSCs) | Clinical study | Cell & Tissue Engineering | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Tooth - diagnostic imaging | Cell Proliferation - genetics | Dental Pulp - pathology | Humans | Male | Tooth - growth & development | Stem Cells - cytology | Tooth - surgery | Pulpitis - therapy | Stem Cell Transplantation | Cell Differentiation - genetics | Dental Pulp - diagnostic imaging | Magnetic Resonance Imaging | Regeneration - genetics | Pulpitis - surgery | Adult | Female | Dental Pulp - growth & development | Pulpitis - pathology | Granulocyte Colony-Stimulating Factor - administration & dosage | Tooth - pathology | Dentin | Nuclear magnetic resonance--NMR | Transplants & implants | Toxicity | Atelocollagen | Transplantation | Granulocytes | Computed tomography | Granulocyte colony-stimulating factor | Bone marrow | Colony-stimulating factor | Manufacturing | Autografts | Stroke | Good Manufacturing Practice | Teeth | Dental caries | Fractures | Magnetic resonance imaging | Stem cells | Root canals | Spinal cord injuries | Endodontics | Leukocytes (granulocytic) | Apoptosis | Dental pulp | Index Medicus
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9. Full Text The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
by Satoh, Takashi and Takeuchi, Osamu and Vandenbon, Alexis and Yasuda, Koubun and Tanaka, Yoshiaki and Kumagai, Yutaro and Miyake, Tohru and Matsushita, Kazufumi and Okazaki, Toshihiko and Saitoh, Tatsuya and Honma, Kiri and Matsuyama, Toshifumi and Yui, Katsuyuki and Tsujimura, Tohru and Standley, Daron M and Nakanishi, Kenji and Nakai, Kenta and Akira, Shizuo
Nature immunology, ISSN 1529-2908, 10/2010, Volume 11, Issue 10, pp. 936 - 944
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Polarity | Macrophage Activation - immunology | Jumonji Domain-Containing Histone Demethylases - immunology | Interferon Regulatory Factors - genetics | Host-Parasite Interactions - immunology | Macrophages - cytology | Nippostrongylus - immunology | Jumonji Domain-Containing Histone Demethylases - genetics | Mice, Knockout | Gene Expression Regulation, Enzymologic | Histone Demethylases - metabolism | Interferon Regulatory Factors - immunology | Animals | Strongylida Infections - immunology | Cell Differentiation | Mice | Chitin - immunology | Methylation | Macrophages - immunology | Macrophages, Alveolar - immunology | Physiological aspects | Research | Methyltransferases | Macrophages | Helminthiasis | Index Medicus
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