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Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A15602 - A15602
BackgroundOur lab recently reported that chondroitin sulphate proteoglycans (CSPGs) accumulate in heart tissue of end-stage heart failure patients. In... 
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1940, pp. 193 - 204
Isolation of healthy, intact cardiomyocytes from the adult mouse heart for cardiac research is challenging. Traditional protocols depend upon specialized... 
Index Medicus
Journal Article
Cardiovascular research, ISSN 0008-6363, 05/2019
We and others have previously described the expression landscape of circular RNA (circRNA) in mouse and human hearts. However, the functional relevance of many... 
Journal Article
Heart, ISSN 1355-6037, 06/2018, Volume 104, Issue Suppl 6, p. A96
RationaleIsolation of high quality myocytes from the adult mouse heart has traditionally required Langendorff perfusion systems, involving a high degree of... 
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4434 - 4
The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell... 
MOUSE HEART | EXPRESSION | MULTIDISCIPLINARY SCIENCES | RESOLUTION | Animals | Sequence Analysis, RNA | Single-Cell Analysis - methods | Humans | Aging | Myocardium - pathology | Heart Diseases - genetics | Heart | Cellular communication | Gene expression | Ribonucleic acid--RNA | Heart diseases | Coronary artery disease | Gene sequencing | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2015, Volume 35, Issue 4, pp. 817 - 828
Objective-Atherosclerosis, the cause of 50% of deaths in westernized societies, is widely regarded as a chronic vascular inflammatory disease. Vascular smooth... 
atherosclerosis | smooth muscle | myocardin | inflammation | APOLIPOPROTEIN E-DEFICIENT | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | BINDING PROTEIN | SERUM RESPONSE FACTOR | CARDIOVASCULAR-DISEASE | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | NF-KAPPA-B | MOLECULAR-MECHANISMS | Inflammation - pathology | Apolipoproteins E - deficiency | Human Umbilical Vein Endothelial Cells - metabolism | Atherosclerosis - genetics | Humans | Muscle, Smooth, Vascular - immunology | Male | Monocytes - immunology | Mice, 129 Strain | Inflammation - metabolism | Neointima | RNA Interference | Time Factors | Nuclear Proteins - deficiency | Carotid Artery Injuries - genetics | Disease Models, Animal | Atherosclerosis - pathology | Atherosclerosis - immunology | Genotype | Lipid Metabolism | Cell Adhesion | Cell Adhesion Molecules - metabolism | Atherosclerosis - metabolism | Mice, Knockout | Macrophages - metabolism | Phenotype | Trans-Activators - deficiency | Carotid Artery Injuries - immunology | Chemokines - metabolism | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Myocytes, Smooth Muscle - pathology | Human Umbilical Vein Endothelial Cells - immunology | Monocytes - metabolism | Transfection | Trans-Activators - genetics | Nuclear Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Macrophages - immunology | Carotid Artery Injuries - pathology | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Chemotaxis | Muscle, Smooth, Vascular - pathology | Animals | Apolipoproteins E - genetics | Inflammation - genetics | Myocytes, Smooth Muscle - immunology | Trans-Activators - metabolism | Index Medicus | Smooth muscle | Inflammation | Myocardin | Atherosclerosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 13, pp. 5449 - 5454
Journal Article
Heart, ISSN 1355-6037, 06/2018, Volume 104, Issue Suppl 6, p. A96
The genetic associations linking the chromosome 9 p21 (chr9p21) locus with cardiovascular diseases, such as aneurysm and coronary artery disease, are well... 
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2013, Volume 33, Issue 10, pp. 2355 - 2365
OBJECTIVE—Myocardin, a potent transcriptional coactivator of serum response factor, is involved in vascular development and promotes a contractile smooth... 
microRNAs | myocardin | carotid arteries | muscle, smooth | signal transduction | MUSCLE-CELL DIFFERENTIATION | STEM-CELLS | PHENOTYPIC MODULATION | ATHEROSCLEROSIS | ANGIOPLASTY | MESSENGER-RNA | muscle | IN-VIVO | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | smooth | Carotid Stenosis - prevention & control | Cell Proliferation | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Myocytes, Smooth Muscle - pathology | Male | MicroRNAs - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Carotid Stenosis - metabolism | Neointima | Transfection | Time Factors | Carotid Stenosis - genetics | Nuclear Proteins - deficiency | Trans-Activators - genetics | Carotid Artery Injuries - genetics | 3' Untranslated Regions | Nuclear Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Carotid Artery, Common - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Rats | Nuclear Proteins - metabolism | Carotid Stenosis - pathology | Mice, Knockout | Carotid Artery Injuries - prevention & control | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Trans-Activators - deficiency | Apolipoproteins E - genetics | Carotid Artery, Common - pathology | Trans-Activators - metabolism | Mice | Cell Movement | Index Medicus
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2015, Volume 82, pp. 13 - 21
Abstract Natriuretic peptide receptor 3 (NPR3) is the clearance receptor for the cardiac natriuretic peptides (NPs). By modulating the level of NPs, NPR3 plays... 
Cardiovascular | Myocardial infarction | Heart failure | Hypoxia | miR-100 | NPR3 | MiR-100 | CIRCULATING MICRORNAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | ATRIAL | HEART-FAILURE | RATS | MICE LACKING | CELL BIOLOGY | EJECTION FRACTION | GENE-EXPRESSION | CARDIOVASCULAR-DISEASE | HYPERTENSION | Myocardial Infarction - blood | Myocardial Infarction - genetics | Humans | Middle Aged | Natriuretic Peptide, Brain - metabolism | Male | Gene Expression Profiling | Heart Failure - blood | RNA, Messenger - metabolism | Case-Control Studies | Hypoxia - metabolism | RNA Interference | Time Factors | Base Sequence | Female | 3' Untranslated Regions | Binding Sites | Disease Models, Animal | Peptide Fragments - metabolism | Receptors, Atrial Natriuretic Factor - metabolism | Down-Regulation | RNA, Messenger - genetics | Gene Expression Regulation | Rats | Heart Failure - genetics | Adrenomedullin - metabolism | Heart Failure - metabolism | Myocardial Infarction - metabolism | Adrenomedullin - genetics | Protein Precursors - metabolism | Hypoxia - genetics | Animals | Receptors, Atrial Natriuretic Factor - chemistry | Myocytes, Cardiac - metabolism | Receptors, Atrial Natriuretic Factor - genetics | RNA, Messenger - chemistry | Aged | MicroRNAs - genetics | MicroRNAs - chemistry | Culture Media, Conditioned - metabolism | Physiological aspects | DNA microarrays | MicroRNA | Analysis | Cardiac patients | Natriuretic peptides | Index Medicus
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 02/2012, Volume 30, Issue 2, pp. 165 - 173
Journal Article
Current Biology, ISSN 0960-9822, 12/2009, Volume 19, Issue 22, pp. 1961 - 1964
The 24-hour rhythms of the circadian clock allow an organism to anticipate daily environmental cycles, giving it a competitive advantage . Although clock... 
SYSBIO | CIRCADIAN CLOCK | ROBUSTNESS | DESIGN | EVOLUTION | RHYTHMS | OSCILLATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYCLES | NOISE | MODEL | SIMULATION | CELL BIOLOGY | Models, Theoretical | Weather | Biological Clocks | Seasons | Genes, Regulator | Index Medicus
Journal Article