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The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 6, pp. 509 - 511
A new study shows that a deficiency of nicotinamide adenine dinucleotide causes congenital malformations. The mechanism is not known, but dietary... 
NADPH | Enzymes | Adenosine | Congenital diseases | Congenital defects | Dietary supplements | Adenine | Prenatal development | Birth defects | Metabolism | NAD | Vitamin B | Nicotinamide | Mutation | Supplementation | Deoxyribonucleic acid--DNA
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 03/2015, Volume 40, Issue 3, p. 130
  To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different... 
Cell growth | Biochemistry | Biosynthesis | Mutation | Metabolism | Cancer
Journal Article
NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 12/2013, Volume 12, Issue 12, pp. 965 - 965
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 5, pp. 1894 - 1899
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1278 - 1283
Control of intracellular reactive oxygen species (ROS) concentrations is critical for cancer cell survival. We show that, in human lung cancer cells, acute... 
Antioxidants | Oxidative stress | Medical research | Cellular metabolism | REPORTS | Erythrocytes | Cell lines | Antibodies | Oxidation | Cell membranes | Hemoglobins | CELLS | OXIDATIVE STRESS | PROTEIN | METABOLISM | MULTIDISCIPLINARY SCIENCES | ROS | TUMOR-SUPPRESSOR | ISOFORM | CANCER | Enzyme Activators - pharmacology | Neoplasm Transplantation | Protein Subunits | Reactive Oxygen Species - metabolism | Oxidative Stress | Glutathione - metabolism | Antioxidants - metabolism | Humans | Pyruvate Kinase - chemistry | Diamide - pharmacology | Transplantation, Heterologous | Neoplasms, Experimental - pathology | Mutant Proteins - antagonists & inhibitors | Cell Line | Oxidation-Reduction | Pyruvate Kinase - metabolism | Cell Survival | Mutant Proteins - genetics | Mutant Proteins - metabolism | Cysteine - chemistry | Pyruvate Kinase - antagonists & inhibitors | Animals | Mice, Nude | Mutant Proteins - chemistry | Acetylcysteine - pharmacology | Cell Line, Tumor | Glucose - metabolism | Mice | Neoplasms, Experimental - metabolism | Pentose Phosphate Pathway | Pyruvate Kinase - genetics | Amino Acid Substitution | Reactive oxygen species | Enzyme inhibitors | Pyruvate kinase | Lung cancer | Cancer cells | Physiological aspects | Oxidation-reduction reaction | Research | Health aspects | Enzymes | Biochemistry | Cellular biology | Kinases | Index Medicus
Journal Article
Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. 1161 - 1165
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1492 - 1499
Journal Article
Science (New York, N.Y.), ISSN 0036-8075, 6/2018, Volume 360, Issue 6392, pp. 962 - 963
Understanding the molecular basis of cancer has led to a revolution in how cancers are classified and treated. Subsets of patients with specific genetic... 
Journal Article
Immunity, ISSN 1074-7613, 05/2019, Volume 50, Issue 5, p. 1129
Metabolic changes affect T lymphocyte function, and understanding this phenomenon could improve immunotherapy. In a recent paper in Science, report that tumor... 
Immunotherapy | T cells
Journal Article
Science, ISSN 0036-8075, 06/2018, Volume 360, Issue 6392, pp. 962 - 963
Journal Article