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1. Full Text Bacterial Coinfection in Influenza: A Grand Rounds Review
by Chertow, Daniel S and Memoli, Matthew J
JAMA, ISSN 0098-7484, 01/2013, Volume 309, Issue 3, pp. 275 - 282
Bacterial coinfection complicated nearly all influenza deaths in the 1918 influenza pandemic and up to 34% of 2009 pandemic influenza A(H1N1) infections... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | COMMUNITY-ACQUIRED PNEUMONIA | ADVISORY-COMMITTEE | STREPTOCOCCUS-PNEUMONIAE | VIRUS | RESPIRATORY-TRACT COMPLICATIONS | PANDEMIC INFLUENZA | STAPHYLOCOCCUS-AUREUS | GLOBAL MORTALITY | H1N1 INFLUENZA | Community-Acquired Infections - diagnosis | Influenza Vaccines - administration & dosage | Coinfection | Humans | Middle Aged | Critical Illness | Male | Influenza, Human - complications | Staphylococcal Infections - complications | Anti-Bacterial Agents - therapeutic use | Community-Acquired Infections - drug therapy | Pneumonia, Bacterial - mortality | Fatal Outcome | Influenza A Virus, H1N1 Subtype | Influenza, Human - mortality | Influenza, Human - diagnosis | Community-Acquired Infections - complications | Influenza, Human - therapy | Community-Acquired Infections - mortality | Staphylococcal Infections - drug therapy | Pneumonia, Bacterial - complications | Pneumonia, Bacterial - diagnosis | Morbidity | Staphylococcal Infections - mortality | Staphylococcal Infections - diagnosis | Critical Care | Pneumonia, Bacterial - drug therapy | Staphylococcus infections | Systematic review | Immunization | Pandemics | Swine flu
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2. Full Text Rapid Selection of Oseltamivirand Peramivir-Resistant Pandemic H1N1 Virus during Therapy in 2 Immunocompromised Hosts
by Matthew J. Memoli and Rachel J. Hrabal and Arash Hassantoufighi and Maryna C. Eichelberger and Jeffery K. Taubenberger
Clinical Infectious Diseases, ISSN 1058-4838, 5/2010, Volume 50, Issue 9, pp. 1252 - 1255
Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We describe rapid selection for the... 
H1N1 subtype influenza A virus | Pandemics | Infectious diseases | Influenza A virus | Antivirals | Viruses | Infections | Immunocompromised hosts | Inhibitory concentration 50 | Genetic mutation | BRIEF REPORTS
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3. Full Text Evaluation of antihemagglutinin and antineuraminidase antibodies as correlates of protection in an influenza A/H1N1 virus healthy human challenge model
by Memoli, Matthew J and Shaw, Pamela A and Han, Alison and Czajkowski, Lindsay and Reed, Susan and Athota, Rani and Bristol, Tyler and Fargis, Sarah and Risos, Kyle and Powers, John H and Davey, Richard T and Taubenberger, Jeffery K
mBio, ISSN 2161-2129, 04/2016, Volume 7, Issue 2, p. e00417
Despite long-term investment, influenza continues to be a significant worldwide problem. The cornerstone of protection remains vaccination, and approved... 
NEURAMINIDASE | IMMUNITY | EFFICACY | TITERS | RESISTANCE | MICROBIOLOGY | PANDEMIC H1N1 | INFECTION | SERUM | REPRODUCIBILITY | VACCINES | Influenza A Virus, H1N1 Subtype - immunology | Influenza Vaccines - administration & dosage | United States | Humans | Middle Aged | Vaccination | Influenza A Virus, H1N1 Subtype - physiology | Male | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Healthy Volunteers | Neuraminidase - immunology | Young Adult | Influenza Vaccines - immunology | Adolescent | Adult | Antibodies, Viral - immunology | Female | Influenza, Human - virology | Influenza, Human - prevention & control | Influenza, Human - immunology
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4. Full Text Efficacy analysis in healthy-volunteer influenza challenge trials: Intention to treat
by Hunsberger, Sally and Memoli, Matthew J
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2018, Volume 62, Issue 1
Clinical trials | Influenza | Challenge studies
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5. Full Text Evaluation of preexisting anti-hemagglutinin stalk antibody as a correlate of protection in a healthy volunteer challenge with influenza A/H1N1pdm virus
by Park, Jae-Keun and Han, Alison and Czajkowski, Lindsay and Reed, Susan and Athota, Rani and Bristol, Tyler and Rosas, Luz Angela and Cervantes-Medina, Adriana and Taubenberger, Jeffery K and Memoli, Matthew J
mBio, ISSN 2161-2129, 01/2018, Volume 9, Issue 1, p. e02284-17
Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of licensed influenza vaccines. Recently, broadly reactive antibodies... 
Antibody | CHIM | Influenza | Universal vaccine | HA stalk | Neuraminidase | Human challenge | Influenza A | influenza | antibody | influenza A | FLU-PRO | HUMANS | MICROBIOLOGY | INDUCTION | STEM | INSTRUMENT | universal vaccine | neuraminidase | human challenge | INFECTION | VACCINES | Influenza A Virus, H1N1 Subtype - immunology | Influenza, Human - pathology | Enzyme-Linked Immunosorbent Assay | Humans | Middle Aged | Male | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Healthy Volunteers | Antibodies, Viral - blood | Hemagglutination Inhibition Tests | Young Adult | Adolescent | Adult | Female | Child | Influenza, Human - prevention & control
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6. Full Text MultiDrug-Resistant 2009 Pandemic Influenza A(H1N1) Viruses Maintain Fitness and Transmissibility in Ferrets
by Matthew J. Memoli and A. Sally Davis and Kathleen Proudfoot and Daniel S. Chertow and Rachel J. Hrabal and Tyler Bristol and Jeffery K. Taubenberger
The Journal of Infectious Diseases, ISSN 0022-1899, 2/2011, Volume 203, Issue 3, pp. 348 - 357
Background. The 2009 influenza A(H1N1) pandemic called attention to the limited influenza treatment options available, especially in individuals at high risk... 
H1N1 subtype influenza A virus | Pulmonary alveoli | Inoculation | Pandemics | Disease transmission | Lungs | Influenza A virus | Antivirals | Weight loss | Viruses | UNITED-STATES | INFECTIOUS DISEASES | ADAMANTANE RESISTANCE | MICROBIOLOGY | IMMUNOLOGY | H1N1 VIRUS | OSELTAMIVIR | NEURAMINIDASE | IN-VITRO | A/H3N2 VIRUS | A VIRUSES | RAPID SELECTION | ISOLATED WORLDWIDE | Antiviral Agents - pharmacology | Global Health | Orthomyxoviridae Infections - veterinary | Humans | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Male | Virus Shedding | Drug Resistance, Multiple, Viral | Ferrets | Influenza A Virus, H1N1 Subtype - drug effects | Lung - virology | Animals | Orthomyxoviridae Infections - transmission | Influenza, Human - virology | Orthomyxoviridae Infections - virology | Major and Brief Reports
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7. Full Text Critically Ill patients with H7N9: New virus, old challenges
by Memoli, Matthew J
Critical Care Medicine, ISSN 0090-3493, 02/2015, Volume 43, Issue 2, pp. 487 - 488
Avian influenza | Influenza A | H7N9 | Pandemic influenza | Influenza | Intensive Care Units | Humans | Critical Illness | Female | Influenza A Virus, H7N9 Subtype | Male | Influenza, Human - physiopathology | influenza | pandemic influenza | avian influenza | influenza A | influenza B
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8. Full Text Using the Influenza Patient-reported Outcome (FLU-PRO) diary to evaluate symptoms of influenza viral infection in a healthy human challenge model
by Han, Alison and Poon, Jiat-Ling and Powers, John H and Leidy, Nancy K and Yu, Ren and Memoli, Matthew J
BMC Infectious Diseases, ISSN 1471-2334, 07/2018, Volume 18, Issue 1, pp. 353 - 9
Background: In clinical studies involving a healthy volunteer human challenge model, a valid and reliable measure to assess the evolution of patient-reported... 
Virus | Human challenge study | Influenza | Symptoms | influenza | NEURAMINIDASE | INFECTIOUS DISEASES | ANTIBODY | Economic aspects | Patient outcomes | Hospital care | Analysis | Medical care, Cost of
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9. Rapid Selection of Oseltamivir- and Peramivir-Resistant Pandemic H1N1 Virus during Therapy in 2 Immunocompromised Hosts
by Matthew J Memoli and Rachel J Hrabal and Arash Hassantoufighi and Maryna C Eichelberger and Jeffery K Taubenberger
Clinical Infectious Diseases, ISSN 1058-4838, 05/2010, Volume 50, Issue 9, p. 1252
  Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We describe rapid selection for the... 
Pandemics | Infectious diseases | Inhibitor drugs | Swine flu | Mutation | Drug resistance | Drug therapy | Antiviral drugs
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10. Full Text The author replies
by Memoli, Matthew J
Critical Care Medicine, ISSN 0090-3493, 04/2011, Volume 39, Issue 4, pp. 926 - 927
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11. Full Text Performance of the inFLUenza Patient-Reported Outcome (FLU-PRO) diary in patients with influenza-like illness (ILI)
by Powers, John H and Bacci, Elizabeth D and Leidy, Nancy K and Poon, Jiat-Ling and Stringer, Sonja and Memoli, Matthew J and Han, Alison and Fairchok, Mary P and Coles, Christian and Owens, Jackie and Chen, Wei-Ju and Arnold, John C and Danaher, Patrick J and Lalani, Tahaniyat and Burgess, Timothy H and Millar, Eugene V and Ridore, Michelande and Hernández, Andrés and Rodríguez-Zulueta, Patricia and Ortega-Gallegos, Hilda and Galindo-Fraga, Arturo and Ruiz-Palacios, Guillermo M and Pett, Sarah and Fischer, William and Gillor, Daniel and Macias, Laura Moreno and DuVal, Anna and Rothman, Richard and Dugas, Andrea and Guerrero, M Lourdes
PLoS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, p. e0194180
The inFLUenza Patient Reported Outcome (FLU-PRO) measure is a daily diary assessing signs/symptoms of influenza across six body systems: Nose, Throat, Eyes,... 
Influenza, Human - pathology | Prospective Studies | Humans | Middle Aged | Self Report | Medical Records | Aged, 80 and over | Adult | Female | Male | Aged | Influenza, Human - physiopathology | Evaluation | Care and treatment | Influenza | Medical care | Diagnosis | Health status indicators | Quality management | Military medicine | Correlation coefficients | Viruses | Preventive medicine | Patients | Pharynx | Disease control | Disease prevention | Infectious diseases | Illnesses | Reproducibility | Correlation analysis | Nose | Reliability analysis | Product development | Adults
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12. Full Text Rapid Selection of a Transmissible Multidrug-Resistant Influenza A/H3N2 Virus in an Immunocompromised Host
by Matthew J. Memoli and Rachel J. Hrabal and Arash Hassantoufighi and Brett W. Jagger and Zong-Mei Sheng and Maryna C. Eichelberger and Jeffery K. Taubenberger
The Journal of Infectious Diseases, ISSN 0022-1899, 5/2010, Volume 201, Issue 9, pp. 1397 - 1403
Background. The overall impact of influenza virus infection in immunocompromised patients is largely unknown. Antigenic drift and genetic variations during... 
Pandemics | Influenza A virus | Antivirals | Viruses | Orthomyxoviridae | Infections | Immunocompromised hosts | Inhibitory concentration 50 | Genetic mutation | H3N2 subtype influenza A virus | MORTALITY | INFECTIOUS DISEASES | SWAB | SEASONAL INFLUENZA | SURVEILLANCE | ADULTS | MICROBIOLOGY | IMMUNOLOGY | OUTBREAK | H1N1 | OSELTAMIVIR | Lymphoma, Mantle-Cell - complications | Drug Resistance, Multiple, Viral - genetics | Influenza A Virus, H3N2 Subtype - drug effects | Virus Replication - genetics | Humans | Molecular Sequence Data | Male | Influenza A Virus, H3N2 Subtype - genetics | Influenza, Human - transmission | Reverse Transcriptase Polymerase Chain Reaction | Lymphoma, Mantle-Cell - virology | Ferrets - virology | Animals | Orthomyxoviridae Infections - transmission | Adult | Influenza, Human - virology | Immunocompromised Host | Influenza, Human - drug therapy | Orthomyxoviridae Infections - virology | Influenza, Human - immunology | Influenza viruses | Immunocompromised host | Genetic variation | Analysis | Genetic aspects | Research | Health aspects
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13. Full Text Severity of pH1N1 influenza A
by Memoli, Matthew J
Critical Care Medicine, ISSN 0090-3493, 04/2011, Volume 39, Issue 4, pp. 926 - 927
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14. Full Text Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies
by Gao, J and Couzens, L and Burke, DF and Wan, HQ and Wilson, P and Memoli, MJ and Xu, XY and Harvey, R and Wrammert, J and Ahmed, R and Taubenberger, JK and Smith, DJ and Fouchier, RAM and Eichelberger, MC
MBIO, ISSN 2150-7511, 03/2019, Volume 10, Issue 2, p. e00307-19
The effectiveness of influenza vaccines against circulating A(H1N1) pdm09 viruses was modest for several seasons despite the absence of antigenic drift of... 
influenza | IMMUNITY | ASSAY | vaccines | VACCINE | HUMANS | MICROBIOLOGY | PANDEMIC H1N1 | SERUM | neuraminidase | antigenic drift | RESISTANCE | INFECTION | MONOCLONAL-ANTIBODIES | monoclonal antibodies | EPITOPES
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15. Full Text Editorial: PH1N1 influenza A: Timing is everything
by Memoli, Matthew J
Critical Care Medicine, ISSN 0090-3493, 10/2010, Volume 38, Issue 10, pp. 2081 - 2082
influenza pathology | influenza A | 1918 | swine influenza | pandemic | H1N1 | flu
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16. Full Text IgG antibodies to dengue enhanced for Fc[gamma]RIIIA binding determine disease severity
by Wang, Taia T and Sewatanon, Jaturong and Memoli, Matthew J and Wrammert, Jens and Bournazos, Stylianos and Bhaumik, Siddhartha Kumar and Pinsky, Benjamin A and Chokephaibulkit, Kulkanya and Onlamoon, Nattawat and Pattanapanyasat, Kovit and Taubenberger, Jeffery K and Ahmed, Rafi and Ravetch, Jeffrey V
Science, ISSN 0036-8075, 01/2017, Volume 355, Issue 6323, p. 395
In some cases, secondary infections of dengue virus can be extremely serious and result in plasma leakage, thrombocytopenia, and hemorrhagic disease. This... 
Immunoglobulins | Dengue hemorrhagic fever | Health aspects | Risk factors | Antigens | Dengue fever | Immunoglobulin G | Dengue | Viral diseases | Antibodies | Viruses | Infections | Vaccines | Patients | Fever | Fc receptors | Receptors | Immunology | Neutralizing | Extreme values
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17. Full Text Recent Human Influenza A/H3N2 Virus Evolution Driven by Novel Selection Factors in Addition to Antigenic Drift
by Matthew J. Memoli and Brett W. Jagger and Vivien G. Dugan and Li Qi and Jadon P. Jackson and Jeffery K. Taubenberger
The Journal of Infectious Diseases, ISSN 0022-1899, 10/2009, Volume 200, Issue 8, pp. 1232 - 1241
Background. Examination of the evolutionary dynamics of complete influenza viral genomes reveals that other processes, in conjunction with antigenic drift,... 
Pathology | Lungs | Influenza A virus | Viruses | Evolution | Amino acids | Orthomyxoviridae | Genetic mutation | H3N2 subtype influenza A virus | Human influenza | INFECTIOUS DISEASES | H3N2 VIRUSES | A VIRUSES | GENOME | REVEALS | Cell Line | Genetic Drift | Lung - pathology | Humans | Orthomyxoviridae Infections - pathology | Selection, Genetic | Antigens, Viral - genetics | Influenza, Human - epidemiology | Male | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Ferrets | Animals | Virus Replication | Dogs | Influenza, Human - virology | Orthomyxoviridae Infections - virology | Antigens | Prognosis | Gene mutations | Influenza | Physiological aspects | Genetic aspects | Research
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18. Full Text Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection
by Walters, KA and Zhu, RQ and Welge, M and Scherler, K and Park, JK and Rahil, Z and Wang, H and Auvil, L and Bushell, C and Lee, MY and Baxter, D and Bristol, T and Rosas, LA and Cervantes-Medina, A and Czajkowski, L and Han, A and Memoli, MJ and Taubenberger, JK and Kash, JC
MBIO, ISSN 2150-7511, 05/2019, Volume 10, Issue 3, p. e00760-19
In this study, we examined the relationships between anti-influenza virus serum antibody titers, clinical disease, and peripheral blood leukocyte (PBL) global... 
IMMUNITY | antibody | PROTECTION | SIGNATURES | DISTINCT | HA stalk antibodies | MICROBIOLOGY | MECHANISMS | INDUCTION | NEURAMINIDASE | PANTHER | HA head antibodies | NA antibodies | T-CELLS | DURATION | host response | influenza | antibody function | immune response | human challenge | immune markers | regulation of gene expression | genomics | microarrays
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19. Full Text Bacterial coinfection in influenza
by Chertow, Daniel S and Memoli, Matthew J
JAMA, The Journal of the American Medical Association, ISSN 0098-7484, 01/2013, Volume 309, Issue 3, p. 275
The article discusses the case of a 58-year-old man presented with fever, cough, myalgias and shortness of breath for 5 days to arrive at a better... 
Care and treatment | Medical case management | Comorbidity | Risk factors | Case studies | Host-bacteria relationships | Control | Influenza | Bacteria, Pathogenic | Causes of | Diagnosis | Health aspects | Methods
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20. Full Text The Natural History of Influenza Infection in the Severely Immunocompromised vs Nonimmunocompromised Hosts
by Memoli, Matthew J and Athota, Rani and Reed, Susan and Czajkowski, Lindsay and Bristol, Tyler and Proudfoot, Kathleen and Hagey, Rachel and Voell, Jocelyn and Fiorentino, Charles and Ademposi, Angela and Shoham, Shmuel and Taubenberger, Jeffery K
Clinical Infectious Diseases, ISSN 1058-4838, 1/2014, Volume 58, Issue 2, pp. 214 - 224
Severely immunocompromised individuals infected with influenza are different from the influenza infected that are nonimmunocompromised. Issues to consider... 
Influenza A | Stem cell transplant | Immunocompromised host | Influenza | influenza | MORTALITY | INFECTIOUS DISEASES | stem cell transplant | influenza A | IMMUNODEFICIENCY-VIRUS-INFECTION | HEMATOPOIETIC STEM-CELL | MICROBIOLOGY | IMMUNOLOGY | RECIPIENTS | PNEUMONIA | SOLID-ORGAN TRANSPLANT | H1N1 VIRUS | THERAPY | COMMUNITY | RAPID SELECTION | immunocompromised host | Influenza, Human - pathology | Prospective Studies | Cytokines - analysis | Humans | Middle Aged | Male | Virus Shedding | Patient Outcome Assessment | Serum - immunology | Young Adult | Nasal Mucosa - immunology | Adolescent | Adult | Female | Aged | Immunocompromised Host | Cytokines - blood | Influenza, Human - immunology | Complications and side effects | Evaluation | Immunosuppression | Outcome and process assessment (Health Care) | Diagnosis | Risk factors | and Commentaries
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