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Nature Immunology, ISSN 1529-2908, 12/2012, Volume 13, Issue 12, p. 1139
Journal Article
Science, ISSN 0036-8075, 3/2004, Volume 303, Issue 5663, pp. 1522 - 1526
Toll-like receptors (TLRs) recognize molecular patterns displayed by microorganisms, and their subsequent activation leads to the transcription of appropriate... 
Kidneys | Urinary bladder | RNA | Epithelial cells | Liver | Cell lines | Bacteria | Ligands | Stop codon | Reports | Infections | RESPONSES | ACTIVATION | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | URINARY-TRACT | PATHOGENS | Tumor Necrosis Factor-alpha - metabolism | Epithelial Cells - metabolism | Humans | Kidney - immunology | Molecular Sequence Data | NF-kappa B - metabolism | Gene Expression Profiling | Colony Count, Microbial | Recombinant Fusion Proteins - metabolism | Toll-Like Receptors | Kidney - metabolism | Transfection | Escherichia coli - pathogenicity | Cloning, Molecular | Receptors, Cell Surface - chemistry | Urinary Tract Infections - microbiology | Urinary Bladder - microbiology | Escherichia coli - growth & development | Amino Acid Sequence | Cell Line | Disease Susceptibility | Signal Transduction | Urinary Bladder - metabolism | Liver - metabolism | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Receptors, Cell Surface - metabolism | Urinary Bladder - immunology | Immunity, Innate | Mice, Knockout | Polymorphism, Genetic | Kidney - microbiology | Macrophages - metabolism | Animals | Escherichia coli Infections - immunology | Mice | Codon, Terminator | Urinary Tract Infections - immunology | Receptors, Cell Surface - genetics | Physiological aspects | Research | Immune system | Pathogens | Molecular structure | Molecular biology | Cells
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 450 - 465.e5
Journal Article
Science, ISSN 0036-8075, 6/2005, Volume 308, Issue 5728, pp. 1626 - 1629
Mammalian Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by dendritic cells (DCs). Although TLRs are clearly involved... 
Molecules | Pathogens | Cytokines | Dendritic cells | Profilins | Ligands | Reports | Mice | Infections | Parasites | Parasite hosts | IMMUNITY | TOLL-LIKE RECEPTOR-5 | STRANDED-RNA | TOXOPLASMA-GONDII INFECTION | RECOGNITION | GENE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | IL-12 | PARASITE | CUTTING EDGE | Toxoplasma - immunology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Molecular Sequence Data | Genes, Protozoan | NF-kappa B - metabolism | Interleukin-12 - blood | Toll-Like Receptors | Protozoan Proteins - metabolism | Transfection | Antigens, Differentiation - metabolism | Protozoan Proteins - chemistry | Microfilament Proteins - metabolism | Contractile Proteins - metabolism | Interleukin-12 - biosynthesis | Amino Acid Sequence | Microfilament Proteins - chemistry | Microfilament Proteins - isolation & purification | Signal Transduction | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Contractile Proteins - chemistry | Myeloid Differentiation Factor 88 | Immunity, Innate | Amino Acid Motifs | Adaptor Proteins, Signal Transducing | Animals | Toxoplasma - genetics | Recombinant Proteins - immunology | Protozoan Proteins - isolation & purification | Microfilament Proteins - immunology | Toxoplasmosis, Animal - immunology | Contractile Proteins - immunology | Contractile Proteins - isolation & purification | Antigens, Differentiation - genetics | Receptors, Immunologic - genetics | Protozoan Proteins - immunology | Receptors, Immunologic - metabolism | Protozoa | Research | Analysis | Proteins | Cellular biology | Protozoan enzymes
Journal Article
Cell Research, ISSN 1001-0602, 02/2011, Volume 21, Issue 2, p. 223
  NF-κB was first discovered and characterized 25 years ago as a key regulator of inducible gene expression in the immune system. Thus, it is not surprising... 
Journal Article
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7712, pp. 114 - 119
Prolonged exposure to microbial products such as lipopolysaccharide can induce a form of innate immune memory that blunts subsequent responses to unrelated... 
BRG1 | MAMMALIAN SWI/SNF COMPLEXES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ENDOTOXIN TOLERANCE | MOUSE | GENE-EXPRESSION | ORGAN FAILURE | SEPSIS | INFLAMMATORY RESPONSE | SEPTIC PATIENTS | Humans | Immunity, Innate - genetics | STAT Transcription Factors - metabolism | Chromatin Assembly and Disassembly - genetics | Male | Shock, Septic - immunology | Lipopolysaccharides - immunology | Immune Tolerance - immunology | HEK293 Cells | Female | Immunologic Memory - genetics | Immunologic Memory - immunology | Macrophages - immunology | Inflammation Mediators - immunology | Sepsis - immunology | Nuclear Proteins - metabolism | Inflammation - immunology | Transcription Factors - metabolism | DNA Helicases - metabolism | Immunity, Innate - immunology | Animals | Immune Tolerance - genetics | Inflammation - genetics | RAW 264.7 Cells | Mice | MicroRNAs - genetics | Physiological research | Chromatin | MicroRNA | Research | Immunologic memory | Infection | Epigenetic inheritance | Immune response | Cytokines | Immunotherapy | Genes | Mortality | Genetic transcription | Health aspects | Mitogens | Regulators | BRG1 protein | Transcription factors | Target recognition | Sucrose | Disseminated infection | Remodeling | Macrophages | Lipopolysaccharides | Microorganisms | Tumor necrosis factor-TNF | Bioindicators | Sugars | Immune system | CRISPR | Immunological memory | Cloning | MiRNA | Health risks | Inflammation | Gene expression | Ribonucleic acid--RNA | Patients | Immunological tolerance | Molecular chains | Chromatin remodeling | Gene silencing | Immunosuppression | MicroRNAs | Biomarkers | Sepsis | Brahma-related gene | Binding sites
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2011, Volume 21, Issue 2, pp. 223 - 244
NF-kB was first discovered and characterized 25 years ago as a key regulator of inducible gene expression in the immune system. Thus, it is not surprising that... 
免疫生物学 | 先天免疫 | 基因表达 | 核因子 | 转录因子 | 哺乳动物 | 免疫反应 | 免疫系统功能
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2011, Volume 12, Issue 8, pp. 695 - 708
Journal Article