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1. Full Text Potential for dose reduction in CT emphysema densitometry with post-scan noise reduction: a phantom study
by Wisselink, Hendrik Joost and Pelgrim, Gert Jan and Rook, Mieneke and van den Berge, Maarten and Slump, Kees and Nagaraj, Yeshu and van Ooijen, Peter and Oudkerk, Matthijs and Vliegenthart, Rozemarijn
The British Journal of Radiology, ISSN 0007-1285, 11/2019, p. 20181019
Objective: The aim of this phantom study was to investigate the effect of scan parameters and noise suppression techniques on the minimum radiation dose for... 
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2. Full Text Assessment of Dynamic Change of Coronary Artery Geometry and Its Relationship to Coronary Artery Disease, Based on Coronary CT Angiography
by van Zandwijk, Jordy K and Tuncay, Volkan and Vliegenthart, Rozemarijn and Pelgrim, Gert Jan and Slump, Cornelis H and Oudkerk, Matthijs and van Ooijen, Peter M. A
Journal of Digital Imaging, ISSN 0897-1889, 11/2019
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3. Full Text Clinical Utility Gene Card for: PGM3 defective congenital disorder of glycosylation
by Jaeken, J and Lefeber, DJ and Matthijs, G
EUROPEAN JOURNAL OF HUMAN GENETICS, ISSN 1018-4813, 11/2019, Volume 27, Issue 11, pp. 1757 - 1760
Review of the analytical and clinical validity as well as of the clinical utility of DNA-based testing for mutations in PGM3 in diagnostic, predictive and... 
MUTATIONS | IGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNODEFICIENCY | DEFICIENCY | GENETICS & HEREDITY | Risk assessment | Glycosylation
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4. Full Text Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial
by Bruls, Yvonne MH and de Ligt, Marlies and Lindeboom, Lucas and Phielix, Esther and Havekes, Bas and Schaart, Gert and Kornips, Esther and Wildberger, Joachim E and Hesselink, Matthijs KC and Muoio, Deborah and Schrauwen, Patrick and Schrauwen-Hinderling, Vera B
EBioMedicine, ISSN 2352-3964, 11/2019, Volume 49, pp. 318 - 330
Type 2 diabetes patients and individuals at risk of developing diabetes are characterized by metabolic inflexibility and disturbed glucose homeostasis. Low... 
L-carnitine | Insulin sensitivity | Acetylcarnitine | Hyperinsulinemic-euglycemic clamp | Metabolic flexibility | Impaired glucose tolerance
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5. Full Text Leveraging European European infrastructures to access 1 million human genomes by 2022
by Saunders, Gary and Baudis, Michael and Becker, Regina and Beltran, Sergi and Béroud, Christophe and Birney, Ewan and Brooksbank, Cath and Brunak, Søren and Van den Bulcke, Marc and sdale, Rachel and Capella-Gutierrez, Salvador and Flicek, Paul and Florindi, Francesco and Goodhand, Peter and Gut, Ivo and Heringa, Jaap and Holub, Petr and Hooyberghs, Jef and Juty, Nick and Keane, Thomas M and Korbel, Jan O and Lappalainen, Ilkka and Leskosek, Brane and Matthijs, Gert and Mayrhofer, Michaela Th and Metspalu, Anes and Navarro, Arcadi and Newhouse, Steven and Nyrönen, Tommi and Page, Angela and Persson, Bengt and Palotie, Aarno and Parkinson, Helen and Rambla, Jordi and Salgado, David and Steinfelder, Erik and Swertz, Morris A and Valencia, Alfonso and Varma, Susheel and Blomberg, Niklas and Scollen, Serena
11/2019, Volume 20, Issue 11
Human genomics is undergoing a step change from being a predominantly research-driven activity to one driven through health care as many countries in Europe... 
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6. Full Text Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022
by Saunders, Gary and Baudis, Michael and Becker, Regina and Beltran, Sergi and Béroud, Christophe and Birney, Ewan and Brooksbank, Cath and Brunak, Søren and Van den Bulcke, Marc and Drysdale, Rachel and Capella-Gutierrez, Salvador and Flicek, Paul and Florindi, Francesco and Goodhand, Peter and Gut, Ivo and Heringa, Jaap and Holub, Petr and Hooyberghs, Jef and Juty, Nick and Keane, Thomas M and Korbel, Jan O and Lappalainen, Ilkka and Leskosek, Brane and Matthijs, Gert and Mayrhofer, Michaela Th and Metspalu, Andres and Navarro, Arcadi and Newhouse, Steven and Nyrönen, Tommi and Page, Angela and Persson, Bengt and Palotie, Aarno and Parkinson, Helen and Rambla, Jordi and Salgado, David and Steinfelder, Erik and Swertz, Morris A and Valencia, Alfonso and Varma, Susheel and Blomberg, Niklas and Scollen, Serena
Nature reviews. Genetics, ISSN 1471-0056, 09/2019, Volume 20, Issue 11, pp. 702 - 702
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Genomes
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7. Full Text Leveraging European infrastructures to access 1 million human genomes by 2022
by Saunders, Gary and Baudis, Michael and Becker, Regina and Beltran, Sergi and Béroud, Christophe and Birney, Ewan and Brooksbank, Cath and Brunak, Søren and Van den Bulcke, Marc and sdale, Rachel and Capella-Gutierrez, Salvador and Flicek, Paul and Florindi, Francesco and Goodhand, Peter and Gut, Ivo and Heringa, Jaap and Holub, Petr and Hooyberghs, Jef and Juty, Nick and Keane, Thomas M and Korbel, Jan O and Lappalainen, Ilkka and Leskosek, Brane and Matthijs, Gert and Mayrhofer, Michaela Th and Metspalu, Anes and Navarro, Arcadi and Newhouse, Steven and Nyrönen, Tommi and Page, Angela and Persson, Bengt and Palotie, Aarno and Parkinson, Helen and Rambla, Jordi and Salgado, David and Steinfelder, Erik and Swertz, Morris A and Valencia, Alfonso and Varma, Susheel and Blomberg, Niklas and Scollen, Serena
Nature Reviews Genetics, ISSN 1471-0056, 11/2019, Volume 20, Issue 11, pp. 693 - 701
Human genomics is undergoing a step change from being a predominantly research-driven activity to one driven through health care as many countries in Europe... 
Molecular Biology | Genetics(clinical) | Genetics | Genomes
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8. Full Text Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022 (Nature Reviews Genetics, (2019), 20, 11, (693-701), 10.1038/s41576-019-0156-9)
by Saunders, Gary and Baudis, Michael and Becker, Regina and Beltran, Sergi and Béroud, Christophe and Birney, Ewan and Brooksbank, Cath and Brunak, Søren and Van den Bulcke, Marc and sdale, Rachel and Capella-Gutierrez, Salvador and Flicek, Paul and Florindi, Francesco and Goodhand, Peter and Gut, Ivo and Heringa, Jaap and Holub, Petr and Hooyberghs, Jef and Juty, Nick and Keane, Thomas M and Korbel, Jan O and Lappalainen, Ilkka and Leskosek, Brane and Matthijs, Gert and Mayrhofer, Michaela Th and Metspalu, Anes and Navarro, Arcadi and Newhouse, Steven and Nyrönen, Tommi and Page, Angela and Persson, Bengt and Palotie, Aarno and Parkinson, Helen and Rambla, Jordi and Salgado, David and Steinfelder, Erik and Swertz, Morris A and Valencia, Alfonso and Varma, Susheel and Blomberg, Niklas and Scollen, Serena
Nature Reviews Genetics, ISSN 1471-0056, 11/2019, Volume 20, Issue 11, pp. 1 - 1
The Table 1 (EU declaration signatory and membership status) of the original article published online contained several errors: the IARC was incorrectly listed... 
Molecular Biology | Genetics(clinical) | Genetics
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9. Full Text Athletes feature greater rates of muscle glucose transport and glycogen synthesis during lipid infusion
by Phielix, E and Begovatz, P and Gancheva, S and Bierwagen, A and Kornips, E and Schaart, G and Hesselink, MKC and Schrauwen, P and Roden, M
JCI INSIGHT, ISSN 2379-3708, 11/2019, Volume 4, Issue 21
BACKGROUND. Insulin resistance results from impaired skeletal muscle glucose transport/phosphorylation, linked to augmented lipid availability. Despite greater... 
PROLONGED SEVERE EXERCISE | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE CAPACITY | GLUT4 EXPRESSION | METABOLISM | PHOSPHORYLATION | FREE FATTY-ACIDS | SENSITIVITY | HUMAN SKELETAL-MUSCLE | INDUCED INSULIN-RESISTANCE | DIACYLGLYCEROLS
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10. Full Text The influence of hypoxia on platelet function and plasmatic coagulation during systemic inflammation in humans in vivo
by Kiers, Dorien and Tunjungputri, Rahajeng N and Borkus, Rowie and Scheffer, Gert-Jan and de groot, Philip G and Urbanus, Rolf T and van der ven, Andre J and Pickkers, Peter and de Mast, Quirijn and Kox, Matthijs
Platelets, ISSN 0953-7104, 10/2019, Volume 30, Issue 7, pp. 927 - 930
Systemic inflammation and hypoxia frequently occur simultaneously in critically ill patients, and are both associated with platelet activation and... 
hypoxia | systemic inflammation | platelet function | Coagulation | endotoxin | THROMBIN GENERATION | HYPOBARIC HYPOXIA | ACTIVATION | HEMATOLOGY | CELL BIOLOGY
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11. Full Text Women desiring less care than recommended during childbirth: Three years of dedicated clinic
by Garde, M. van der and Hollander, M.H and Olthuis, G.J and Vandenbussche, F.P and Dillen, J. van
Birth : Issues in Perinatal Care, ISSN 0730-7659, 2019, Volume 46, Issue 2, pp. 262 - 269
BACKGROUND: Some women decline recommended care during pregnancy and birth. This can cause friction between client and provider. METHODS: A designated... 
HOME BIRTH | CHOICE | NURSING | PEDIATRICS | EXPERIENCE | NARRATIVES | HOMEBIRTH | MOTIVATIONS | OBSTETRICS & GYNECOLOGY | Analysis | Childbirth | Pregnancy | Medical personnel | Compromises | Womens health | Pregnant women | Perinatal | Patient satisfaction | Interdisciplinary approach | Preferences | Birth plans | Childbirth & labor
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12. Full Text Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype
by Blommaert, E and Peanne, R and Cherepanova, NA and Rymen, D and Staels, F and Jaeken, J and Race, V and Keldermans, L and Souche, E and Corveleyn, A and Sparkes, R and Bhattacharya, K and Devalck, C and Schrijvers, R and Foulquier, F and Gilmore, R and Matthijs, G
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2019, Volume 116, Issue 20, pp. 9865 - 9870
Congenital disorders of glycosylation (CDG) are a group of rare metabolic diseases, due to impaired protein and lipid glycosylation. We identified two patients... 
CELLS | OXIDOREDUCTASE ACTIVITY | MULTIDISCIPLINARY SCIENCES | CDG | XMEN | CONGENITAL DISORDERS | SITES | oligosaccharyltransferase complex | SUBUNITS | N-GLYCOSYLATION | congenital disorders of glycosylation | Transferrin | Phenotypes | Immunodeficiency | Homeostasis | Homology | Lipids | Glycosylation | Oligosaccharyltransferase | Substrates | Proteins | Genotype & phenotype | Magnesium | Mutation | Transporter | Metabolic disorders | Biological Sciences
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13. Full Text Long-term follow-up in PMM2-CDG: are we ready to start treatment trials?
by Witters, Peter and Honzik, Tomas and Bauchart, Eric and Altassan, Ruqaiah and Pascreau, Tiffany and Bruneel, Arnaud and Vuillaumier, Sandrine and Seta, Nathalie and Borgel, Delphine and Matthijs, Gert and Jaeken, Jaak and Meersseman, Wouter and Cassiman, David and Pascale de, Lonlay and Morava, Eva
Genetics in Medicine, ISSN 1098-3600, 2018, Volume 21, Issue 5, pp. 1181 - 1188
Purpose: PMM2-CDG is the most common congenital disorder of glycosylation (CDG), which presents with either a neurologic or multisystem phenotype. Little is... 
PMM2-CDG | CDG severity scale | coagulation | long-term follow-up | liver function test | GLYCOSYLATION TYPE-IA | GENETICS & HEREDITY | CONGENITAL DISORDERS | SPECTRUM | CDG-IA | long-term followup | FIBROBLASTS
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14. Full Text Early imaging biomarkers of lung cancer, COPD and coronary artery disease in the general population: rationale and design of the ImaLife (Imaging in Lifelines) Study
by Xia, Congying and Rook, Mieneke and Pelgrim, Gert Jan and Sidorenkov, Grigory and Wisselink, Hendrik J and van Bolhuis, Jurjen N and van Ooijen, Peter M A and Guo, Jiapan and Oudkerk, Matthijs and Groen, Harry and van den Berge, Maarten and van der Harst, Pim and Dijkstra, Hildebrand and Vonder, Marleen and Heuvelmans, Marjolein A and Dorrius, Monique D and De Deyn, Peter Paul and de Bock, Geertruida H and Dotinga, Aafje and Vliegenthart, Rozemarijn
European journal of epidemiology, ISSN 0393-2990, 04/2019, pp. 1 - 12
Lung cancer, chronic obstructive pulmonary disease (COPD), and coronary artery disease (CAD) are expected to cause most deaths by 2050. State-of-the-art... 
Calcification (ectopic) | State of the art | Calcium | Lung nodules | Lung cancer | Radiation | Cardiovascular disease | Computed tomography | Aging | Population | Occupational health | Chronic obstructive pulmonary disease | Bioindicators | Heart diseases | Cardiovascular system | Medical imaging | Lung diseases | Coronary artery | Health risks | Wall thickness | Coronary artery disease | Radiation dosage | Nodules | Arteriosclerosis | Coronary vessels | Obstructive lung disease | Computer aided tomography | Biomarkers | Cancer
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15. Full Text Low CT temporal sampling rates result in a substantial underestimation of myocardial blood flow measurements
by van Assen, Marly and Pelgrim, Gert Jan and Slager, Emmy and van Tuijl, Sjoerd and Schoepf, U Joseph and Vliegenthart, Rozemarijn and Oudkerk, Matthijs
International Journal Of Cardiovascular Imaging, ISSN 1569-5794, 03/2019, Volume 35, Issue 3, pp. 539 - 547
The purpose of this study was to evaluate the effect of temporal sampling rate in dynamic CT myocardial perfusion imaging (CTMPI) on myocardial blood flow... 
Medicine & Public Health | Perfusion imaging | Computed tomography | Cardiology | Imaging / Radiology | Cardiac Imaging | Cardiac imaging techniques | ABSOLUTE | CARDIAC & CARDIOVASCULAR SYSTEMS | QUANTIFICATION | DISEASE | PERFUSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COMPUTED-TOMOGRAPHY | DIAGNOSTIC PERFORMANCE | Coronary Stenosis - diagnostic imaging | Severity of Illness Index | Predictive Value of Tests | Reproducibility of Results | Isolated Heart Preparation | Tomography, Emission-Computed, Single-Photon | Cardiac-Gated Imaging Techniques | Positron-Emission Tomography | Computed Tomography Angiography | Proof of Concept Study | Myocardial Perfusion Imaging - methods | Animals | Fractional Flow Reserve, Myocardial | Time Factors | Coronary Stenosis - physiopathology | Blood Flow Velocity | Electrocardiography | Sus scrofa | Disease Models, Animal | Measurement | CT imaging | Electrocardiogram | Diagnostic imaging | Medical imaging equipment | Blood flow | EKG | Heart | Medical imaging | Stenosis | Single photon emission computed tomography | Blood | Weight | Flow | Ischemia | Perfusion | Rot | Tomography | Myocardium | Computer aided tomography | Sampling | Quantitative analysis | Original Paper
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16. Full Text Low CT temporal sampling rates result in a substantial underestimation of myocardial blood flow measurements
by van Assen, Marly and Pelgrim, Gert Jan and Slager, Emmy and van Tuijl, Sjoerd and Schoepf, U. Joseph and Vliegenthart, Rozemarijn and Oudkerk, Matthijs
The International Journal of Cardiovascular Imaging, ISSN 1569-5794, 03/2019, Volume 35, Issue 3, pp. 539 - 547
The purpose of this study was to evaluate the effect of temporal sampling rate in dynamic CT myocardial perfusion imaging (CTMPI) on myocardial blood flow... 
Comparative Study | Perfusion imaging | Computed tomography | Journal Article | Cardiac imaging techniques
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17. Full Text Upsetting the apple cart? Export fruit production, water pollution and social unrest in the Elgin Valley, South Africa
by Wessels, Matthijs and Veldwisch, Gert Jan and Kujawa, Katarzyna and Delcarme, Brian
Water International, ISSN 0250-8060, 02/2019, Volume 44, Issue 2, pp. 188 - 205
This article explores the encounter between two contrasting visions of how the hydrosocial territory of the Elgin Valley of South Africa is, and should be,... 
water pollution | South Africa | rural-urban struggles | fruit exports | Hydrosocial territories | STRUGGLES | ENGINEERING, CIVIL | AGRICULTURE | WATER RESOURCES | LAND-REFORM | JUSTICE | Economics | Territory | Farmers | Crop production | Economic importance | Political institutions | Exports and imports | Land | Social unrest | Pollution | Disputes | Historical account | Water pollution | Inequality
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18. Full Text Virtuelle Entwicklung aktiver Lichtfunktionen
by Klomp, Matthijs and Wareborn, Victor
02/2019, Volume 121, Issue 2
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19. Full Text International clinical guidelines for the management of phosphomannomutase 2-congenital disorders of glycosylation: Diagnosis, treatment and follow up
by Altassan, R and Peanne, R and Jaeken, J and Barone, R and Bidet, M and Borgel, D and Brasil, S and Cassiman, D and Cechova, A and Coman, D and Corral, J and Correia, J and Morena-Barrio, M.E. de la and Lonlay, P. de and Reis, V. Dos and Ferreira, C.R and Fiumara, A and Francisco, R and Freeze, H and Funke, S and Gardeitchik, T and Gert, M and Girad, M and Giros, M and Grunewald, S and Hernandez-Caselles, T and Honzik, T and Hutter, M and Krasnewich, D and Lam, C and Lee, J and Lefeber, D.J and Marques-de-Silva, D and Martinez, A.F and Moravej, H and Ounap, K and Pascoal, C and Pascreau, T and Patterson, M and Quelhas, D and Raymond, K and Sarkhail, P and Schiff, M and Seroczynska, M and Serrano, M and Seta, N and Sykut-Cegielska, J and Thiel, C and Tort, F and Vals, M.A and Videira, P and Witters, P and Zeevaert, R and Morava, E
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 2019, Volume 42, Issue 1, pp. 5 - 28
Phosphomannomutase 2 (PMM2-CDG) is the most common congenital disorder of N-glycosylation and is caused by a deficient PMM2 activity. The clinical presentation... 
MEDICINE, RESEARCH & EXPERIMENTAL | DEFICIENT GLYCOPROTEIN SYNDROME | HYPERINSULINEMIC HYPOGLYCEMIA | LINKED GLYCOSYLATION | CONGENITAL DISORDER | IA CDG-IA | HYPERTROPHIC CARDIOMYOPATHY | DEEP VENOUS THROMBOSIS | CEREBELLAR-ATAXIA | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | PERICARDIAL-EFFUSION | PRENATAL-DIAGNOSIS | Literature reviews | Systematic review | Glycosylation | Diagnosis | Management | Phosphomannomutase | Patients
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20. Full Text Intermodel disagreement of myocardial blood flow estimation from dynamic CT perfusion imaging
by van Assen, Marly and Pelgrim, Gert Jan and De Cecco, Carlo N and Stijnen, J. Marco A and Zaki, Beatrice M and Oudkerk, Matthijs and Vliegenthart, Rozemarijn and Schoepf, U. Joseph
European Journal of Radiology, ISSN 0720-048X, 01/2019, Volume 110, pp. 175 - 180
To assess the intermodel agreement of different tracer kinetic models to determine myocardial blood flow (MBF) and their diagnostic accuracy in coronary artery... 
Myocardium | Computed tomography | Perfusion imaging | Tracer kinetic models | ABSOLUTE | GLOBAL QUANTIFICATION | ACCURACY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CT imaging | Tracers (Biology) | Cardiac patients | SPECT imaging | Coronary heart disease | Medical imaging equipment | Blood flow
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