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index medicus (34) 34
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ammunition (4) 4
angiopoietin-like 4 protein (4) 4
angiopoietin-like protein-4 (4) 4
ballistic gelatine (4) 4
chemotherapy (4) 4
deflection (4) 4
differentiation-related protein (4) 4
droplets (4) 4
fatty-acids (4) 4
gene expression (4) 4
insulin (4) 4
lipoprotein lipase (4) 4
mice, knockout (4) 4
observational study (4) 4
pathology (4) 4
polyethylene glycols (4) 4
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research article (4) 4
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rna interference (4) 4
rna, messenger - genetics (4) 4
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studies (4) 4
trajectories (4) 4
treatment outcome (4) 4
triglyceride lipase (4) 4
adipocytes (3) 3
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adrp expression (3) 3
antineoplastic combined chemotherapy protocols - therapeutic use (3) 3
area under curve (3) 3
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bullet trajectory deflection (3) 3
cells, cultured (3) 3
chair nutrition metabolism and genomics (3) 3
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lipase (3) 3
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1. Full Text Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise
by Catoire, M and Alex, S and Paraskevopulos, N and Mattijssen, F and Evers-van Gogh, I and Schaart, G and Jeppesen, J and Kneppers, A and Mensink, M and Voshol, P.J and Olivecrona, G and Tan, N.S and Hesselink, M.K and Berbee, J.F and Rensen, P.C and Kalkhoven, E and Schrauwen, P and Kersten, S and Medicinska fakulteten and Fysiologisk kemi and Institutionen för medicinsk biovetenskap and Umeå universitet
Proceedings of the National Academy of Science USA, ISSN 0027-8424, 2014, Volume 111, Issue 11, pp. E1043 - 52
Physical activity increases energy metabolism in exercising muscle. Whether acute exercise elicits metabolic changes in nonexercising muscles remains unclear.... 
POSTPRANDIAL TRIACYLGLYCEROL | INSULIN-RESISTANCE | ENDURANCE EXERCISE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RECEPTOR | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | EXPRESSION | HUMAN SKELETAL-MUSCLE | ADIPOSE-TISSUE | Angiopoietins - metabolism | Humans | Middle Aged | Male | Muscle, Skeletal - physiology | Angiopoietins - blood | Angiopoietin-like 4 Protein | Microarray Analysis | Homeostasis - physiology | Fluorescent Antibody Technique | Adult | Exercise - physiology | Angiopoietins - physiology | Fatty Acids - metabolism | Lipid Metabolism - physiology | PNAS Plus | Biological Sciences | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Fysiologi | Cell and Molecular Biology | Physiology | Cell- och molekylärbiologi | in-vivo | insulin-resistance | expression | receptor | angiopoietin-like protein-4 | endurance exercise | lipoprotein-lipase | human skeletal-muscle | adipose-tissue | postprandial triacylglycerol
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2. Full Text Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study
by K. M. Holtzer-Goor and M. R. Schaafsma and P. Joosten and E. F. M. Posthuma and S. Wittebol and P. C. Huijgens and E. J. M. Mattijssen and G. Vreugdenhil and H. Visser and W. G. Peters and Z. Erjavec and P. W. Wijermans and S. M. G. J. Daenen and K. G. van der Hem and M. H. J. van Oers and C. A. Uyl-de Groot
Quality of Life Research, ISSN 0962-9343, 12/2015, Volume 24, Issue 12, pp. 2895 - 2906
Purpose To describe the health-related quality of life (HRQoL) of an unselected population of patients with chronic lymphocytic leukaemia (CLL) including... 
CLINICAL AND POLICY APPLICATIONS | Lymphocytic | B cell | Public Health | Chronic | Observational study | Medicine & Public Health | Quality of Life Research | Sociology, general | Leukaemia | Quality of life | Area under curve | TRIALS | EQ-5D | INFECTIONS | FLUDARABINE PLUS CYCLOPHOSPHAMIDE | CANCER | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | THERAPY | HEALTH CARE SCIENCES & SERVICES | HEALTH POLICY & SERVICES | QLQ-C30 | EUROPEAN-ORGANIZATION | Chlorambucil - adverse effects | Chlorambucil - therapeutic use | Humans | Middle Aged | Fatigue - psychology | Male | Sleep Wake Disorders - psychology | Dyspnea - psychology | Netherlands | Quality of Life | Adult | Female | Surveys and Questionnaires | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Health Status | Leukemia, Lymphocytic, Chronic, B-Cell - psychology | Longitudinal Studies | Patients | Leukemia | Chronic illnesses
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3. Full Text Regulation of triglyceride metabolism by Angiopoietin-like proteins
by Mattijssen, Frits and Kersten, Sander
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 05/2012, Volume 1821, Issue 5, pp. 782 - 789
Plasma triglyceride concentrations are determined by the balance between production of the triglyceride-rich lipoproteins VLDL and chylomicrons in liver and... 
Angiopoietin-like proteins | Triglycerides | Lipoprotein lipase | PPARs | activated receptor-beta/delta | coiled-coil domain | ppar-beta/delta | plasma triglyceride | fatty-acids | proprotein convertases | adipose-tissue | growth-factor | lipoprotein-lipase activity | diet-induced obesity | COILED-COIL DOMAIN | LIPID-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPOPROTEIN-LIPASE | PLASMA TRIGLYCERIDE | ACTIVATED RECEPTOR-BETA/DELTA | CELL BIOLOGY | GENETIC-VARIATION | BIOPHYSICS | SERUM-LEVELS | GROWTH-FACTOR | PPAR-BETA/DELTA | ADIPOSE-TISSUE | Proteins | Oligomers | Fasting | Physiological aspects | Blood lipids | Lipase | Gene expression | Fatty acids
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4. Full Text Rifle bullet deflection through a soft tissue simulant
by Riva, F and Mattijssen, E.J.A.T and Kerkhoff, W
Forensic Science International, ISSN 0379-0738, 10/2018, Volume 291, pp. 199 - 206
Trajectory deflections of 5.56 NATO and 7.62 × 39 mm rifle bullets, fired through 7.5, 15 and 22.5 cm of gelatine, were studied. The magnitude of the... 
Shooting incident reconstruction | Bullet trajectory reconstruction | Ballistic gelatine | Soft tissue simulant | Bullet trajectory deflection | WOUND BALLISTICS | UNSTABLE PROJECTILES | ORDNANCE GELATIN | MEDICINE, LEGAL | Causes of | Soft tissue injuries | Research | Gunshot wounds | Forensic ballistics | Temperature | Stability | Deflection | Projectiles | Perforation | Trajectories | Shootings | Firearms | Velocity | Perforating | Penetration depth | Studies | Energy | Ammunition
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5. Full Text Bivalent Vaccine Effectiveness Against Type-Specific HPV Positivity: Evidence for Cross-Protection Against Oncogenic Types among Dutch STI Clinic Visitors
by Woestenberg, P.J and King, A.J and Benthem, Birgit and Donken, R and Leussink, S and Klis, Fiona and Melker, Hester and Sande, Marianne and Hoebe, Christian and Bogaards, Johannes and Med Microbiological Labs Public and Medical Microbiological Laboratories and the Public Health Services
The Journal of Infectious Diseases, ISSN 0022-1899, 01/2018, Volume 217, Issue 2, pp. 213 - 222
markdownabstractBackground: Observational postmarketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human... 
vaccine effectiveness | human papillomavirus vaccine | public health | human papillomavirus | Cervarix | BROAD-SPECTRUM | INFECTIOUS DISEASES | EFFICACY | OF-STUDY ANALYSIS | MICROBIOLOGY | IMMUNOLOGY | INTRAEPITHELIAL NEOPLASIA | HPV-16/18 AS04-ADJUVANTED VACCINE | HUMAN-PAPILLOMAVIRUS VACCINATION | INVASIVE CERVICAL-CANCER | BLIND PATRICIA TRIAL | INFECTION | PCR ASSAY | Treatment outcome | Care and treatment | Dosage and administration | Papillomavirus infections | Poliomyelitis vaccine | Analysis | Major and Brief Reports
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6. Full Text Melphalan, prednisone, and lenalidomide versus melphalan, prednisone, and thalidomide in untreated multiple myeloma
by Zweegman, S and Holt, B. van der and Mellqvist, U.H and Salomo, M and Bos, G.M and Levin, M.D and Visser-Wisselaar, H and Hansson, M and Velden, A.W. van der and Deenik, W and Gruber, A and Coenen, J.L and Plesner, T and Klein, S.K and C., T.B and Szatkowski, D.L and Brouwer, R.E and Westerman, M and Leys, M.R and Sinnige, H.A and Haukås, E and Hem, K.G. van der and Durian, M.F and Mattijssen, E.V and Donk, N.W. van de and Stevens-Kroef, M.J and Sonneveld, P and Waage, A and Lund University and Division of Hematology and Transfusion Medicine and Myeloma research group and BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation and Lunds universitet and Avdelningen för hematologi och transfusionsmedicin and Myelomgruppen
Blood, ISSN 0006-4971, 2016, Volume 127, Issue 9, pp. 1109 - 1116
The combination of melphalan, prednisone, and thalidomide (MPT) is considered standard therapy for newly diagnosed patients with multiple myeloma who are... 
NETWORK | 2ND MALIGNANCIES | METAANALYSIS | THERAPY | NEWLY-DIAGNOSED MYELOMA | RANDOMIZED-TRIAL | PLUS THALIDOMIDE | INDIVIDUAL PATIENT DATA | HEMATOLOGY | ELDERLY-PATIENTS | TRANSPLANTATION | Thalidomide - adverse effects | Humans | Middle Aged | Male | Treatment Outcome | Prednisone | Melphalan - therapeutic use | Withholding Treatment | Disease-Free Survival | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Melphalan - adverse effects | Aged, 80 and over | Female | Aged | Maintenance Chemotherapy | Thalidomide - therapeutic use | Index Medicus | Abridged Index Medicus | Clinical Medicine | Hematologi | Medical and Health Sciences | Hematology | Klinisk medicin | Medicin och hälsovetenskap
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7. Full Text Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels
by Bosma, Madeleen and Hesselink, Matthijs K. C and Sparks, Lauren M and Timmers, Silvie and Ferraz, Maria João and Mattijssen, Frits and van Beurden, Denis and Schaart, Gert and de Baets, Marc H and Verheyen, Fons K and Kersten, Sander and Schrauwen, Patrick
Diabetes, ISSN 0012-1797, 2012, Volume 61, Issue 11, pp. 2679 - 2690
Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid (IMCL) storage exceeds intracellular needs and... 
ADRP EXPRESSION | LIVER-CELLS | ENDOCRINOLOGY & METABOLISM | TRIGLYCERIDE LIPASE | RESISTANCE | FATTY-ACIDS | DEFICIENT MICE | TRIACYLGLYCEROL | ACCUMULATION | DIFFERENTIATION-RELATED PROTEIN | DROPLETS | Rats, Wistar | Diet, High-Fat - adverse effects | Male | Muscle, Skeletal - metabolism | Gene Expression Profiling | RNA Interference | Cytoplasmic Granules - metabolism | Muscle Proteins - metabolism | Female | Membrane Proteins - metabolism | Recombinant Proteins - metabolism | Cell Line | Gene Transfer Techniques | Membrane Proteins - genetics | Mice, Inbred C57BL | Insulin Resistance | Muscle, Skeletal - ultrastructure | Oxidative Phosphorylation | Rats | Electroporation | Lipid Metabolism | Muscle Proteins - genetics | Animals | Cytoplasmic Granules - ultrastructure | Membrane Proteins - antagonists & inhibitors | Mice | RNA, Small Interfering | Perilipin-2 | Physiological aspects | Muscles | Cellular proteins | Research | Insulin | Analysis | Metabolism
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8. Full Text Pistol bullet deflection through soft tissue simulants
by Kerkhoff, W and Bolck, A and Alberink, I and Mattijssen, E.J.A.T and Hermsen, R and Riva, F
Forensic Science International, ISSN 0379-0738, 08/2018, Volume 289, pp. 270 - 276
Trajectory deflections of pistol bullets from four different firearms, fired through soft tissue simulants under two different incidence and exit angles were... 
Soft-tissue simulant | Skin simulant | Bullet trajectory reconstruction | Ballistic gelatine | Bullet trajectory deflection | MEDICINE, LEGAL | BALLISTIC GELATIN | Tissues | Research | Forensic ballistics | Temperature | Deflection | Projectiles | Shooting | Trajectories | Firearms | Shootings | Soft tissues | Studies | Small arms | Ammunition | Bones | Standard deviation | Skin | Incidence angle
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9. Full Text Quality of dietary intake in relation to body composition in patients with chronic obstructive pulmonary disease eligible for pulmonary rehabilitation
by van de Bool, C and Mattijssen Verdonschot, C and van Melick, P.P.M.J and Spruit, M.A and Franssen, F.M.E and Wouters, E.F.M and Schols, A.M.W.J and Rutten, E.P.A
European Journal of Clinical Nutrition, ISSN 0954-3007, 01/2014, Volume 68, Issue 2, pp. 159 - 165
BACKGROUND/OBJECTIVES: A poor dietary quality may accelerate disturbances in body composition in chronic obstructive pulmonary disease (COPD), but only limited... 
CAPACITY | ACIDS | FOOD-INTAKE | PATTERNS | VITAMIN-D STATUS | PREVALENCE | ENERGY-BALANCE | nutrition | body composition | NUTRITION & DIETETICS | dietary intake | abdominal obesity | FAT | SEVERITY | COPD | Body Composition | Dietary Carbohydrates - administration & dosage | Dietary Proteins - administration & dosage | Food Quality | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - complications | Nutrition Policy | Energy Intake | Netherlands | Pulmonary Disease, Chronic Obstructive - therapy | Obesity, Abdominal - complications | Diet | Calcium, Dietary - administration & dosage | Pulmonary Disease, Chronic Obstructive - rehabilitation | Dietary Fats - administration & dosage | Adult | Female | Vitamin D - administration & dosage | Aged | Respiratory Function Tests | Micronutrients - administration & dosage | Development and progression | Lung diseases, Obstructive | Minerals in nutrition | Risk factors | Obesity | Chronic obstructive pulmonary disease | Nutrition | Body fat | Abdomen | Index Medicus
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10. Full Text Primary Granulocyte Colony-Stimulating Factor Prophylaxis During the First Two Cycles Only or Throughout All Chemotherapy Cycles in Patients With Breast Cancer at Risk for Febrile Neutropenia
by Maureen J. Aarts and Frank P. Peters and Caroline M. Mandigers and M. Wouter Dercksen and Jacqueline M. Stouthard and Hans J. Nortier and Hanneke W. van Laarhoven and Laurence J. van Warmerdam and Agnes J. van de Wouw and Esther M. Jacobs and Vera Mattijssen and Carin C. van der Rijt and Tineke J. Smilde and Annette W. van der Velden and Mehmet Temizkan and Erdogan Batman and Erik W. Muller and Saskia M. van Gastel and George F. Borm and Vivianne C.G. Tjan-Heijnen
Journal of Clinical Oncology, ISSN 0732-183X, 12/2013, Volume 31, Issue 34, pp. 4290 - U20
Purpose Early breast cancer is commonly treated with anthracyclines and taxanes. However, combining these drugs increases the risk of myelotoxicity and may... 
CELL LUNG-CANCER | ADJUVANT DOCETAXEL | ANTIBIOTICS | ONCOLOGY | CYCLOPHOSPHAMIDE | PHASE-III | DOXORUBICIN | TAC | PREVENTION | TOXICITY | UPDATE | Recombinant Proteins - therapeutic use | Multivariate Analysis | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Prospective Studies | Febrile Neutropenia - chemically induced | Humans | Middle Aged | Netherlands - epidemiology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Febrile Neutropenia - prevention & control | Filgrastim | Incidence | Early Termination of Clinical Trials | Time Factors | Female | Drug Administration Schedule | Polyethylene Glycols | Febrile Neutropenia - epidemiology | Risk Factors | Treatment Outcome | Granulocyte Colony-Stimulating Factor - therapeutic use | Breast Neoplasms - drug therapy | Recombinant Proteins - administration & dosage | Aged | Granulocyte Colony-Stimulating Factor - administration & dosage
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11. Full Text Cost Effectiveness of Primary Pegfilgrastim Prophylaxis in Patients With Breast Cancer at Risk of Febrile Neutropenia
by Maureen J. Aarts and Janneke P. Grutters and Frank P. Peters and Caroline M. Mandigers and M. Wouter Dercksen and Jacqueline M. Stouthard and Hans J. Nortier and Hanneke W. van Laarhoven and Laurence J. van Warmerdam and Agnes J. van de Wouw and Esther M. Jacobs and Vera Mattijssen and Carin C. van der Rijt and Tineke J. Smilde and Annette W. van der Velden and Mehmet Temizkan and Erdogan Batman and Erik W. Muller and Saskia M. van Gastel and Manuela A. Joore and George F. Borm and Vivianne C. Tjan-Heijnen
Journal of Clinical Oncology, ISSN 0732-183X, 12/2013, Volume 31, Issue 34, pp. 4283 - 4289
Purpose Guidelines advise primary granulocyte colony-stimulating factor (G-CSF) prophylaxis during chemotherapy if risk of febrile neutropenia (FN) is more... 
CELL LUNG-CANCER | ADULT PATIENTS | 5-FLUOROURACIL | COLONY-STIMULATING FACTOR | REDUCTION | ONCOLOGY | RECOMMENDATIONS | GUIDELINES | UPDATE | NETHERLANDS | CHEMOTHERAPY | Drug Costs | Recombinant Proteins - therapeutic use | Prospective Studies | Breast Neoplasms - economics | Febrile Neutropenia - chemically induced | Granulocyte Colony-Stimulating Factor - economics | Humans | Middle Aged | Antineoplastic Agents - administration & dosage | Models, Economic | Febrile Neutropenia - prevention & control | Filgrastim | Netherlands | Time Factors | Antineoplastic Agents - adverse effects | Adult | Female | Drug Administration Schedule | Polyethylene Glycols | Risk Factors | Treatment Outcome | Granulocyte Colony-Stimulating Factor - therapeutic use | Breast Neoplasms - drug therapy | Recombinant Proteins - administration & dosage | Recombinant Proteins - economics | Cost-Benefit Analysis | Aged | Febrile Neutropenia - economics | Granulocyte Colony-Stimulating Factor - administration & dosage
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12. Full Text Possible influences on bullet trajectory deflection in ballistic gelatine
by Riva, Fabiano and Kerkhoff, Wim and Bolck, Annabel and Mattijssen, Erwin J.A.T
Forensic Science International, ISSN 0379-0738, 2016, Volume 271, pp. 107 - 112
Highlights • A model to study bullet deflection due to gelatine perforation is proposed. • Deflection angles seem to be constant for an established gelatine... 
Pathology | Terminal ballistics | Ballistic gelatine | Bullet trajectory deflection | MEDICINE, LEGAL | Research | Forensic ballistics | Studies | Influence | Shootings | Velocity | Experiments | Projection | Trajectories | Forensic science | Deflection | Projectiles | Shot
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13. Full Text Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40
by Rijneveld, A. W and van der Holt, B and Daenen, S. M. G. J and Biemond, B. J and de Weerdt, O and Muus, P and Maertens, J and Mattijssen, V and Demuynck, H and Legdeur, M. C. J. C and Wijermans, P. W and Wittebol, S and Spoelstra, F. M and Dekker, A. W and Ossenkoppele, G. J and Willemze, R and Cornelissen, J. J and Dutch-Belgian Hovon Cooperative Gr and Dutch-Belgian HOVON Cooperative group and on behalf of the Dutch-Belgian HOVON Cooperative group
Leukemia, ISSN 0887-6924, 2011, Volume 25, Issue 11, pp. 1697 - 1703
Event-free survival (EFS) at 5 years in pediatric acute lymphoblastic leukemia (ALL) is >80%. Outcome in adult ALL is still unsatisfactory, which is due to... 
ALL | adult | therapy | pediatric | YOUNG-ADULTS | PROTOCOLS | STANDARD-RISK | CHILDREN | TRIAL | RELAPSE | 1ST | ONCOLOGY | ADOLESCENTS | STEM-CELL TRANSPLANTATION | HEMATOLOGY | REMISSION | Precursor Cell Lymphoblastic Leukemia-Lymphoma - surgery | Humans | Middle Aged | Male | Combined Modality Therapy | Remission Induction | Feasibility Studies | Young Adult | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Bone Marrow Transplantation | Adult | Female | Care and treatment | Chemotherapy | Demographic aspects | Patient outcomes | Stem cells | Transplantation | Acute lymphocytic leukemia | Research | Cancer
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14. Full Text Defective i6A37 Modification of Mitochondrial and Cytosolic tRNAs Results from Pathogenic Mutations in TRIT1 and Its Substrate tRNA
by Yarham, John W and Lamichhane, Tek N and Pyle, Angela and Mattijssen, Sandy and Baruffini, Enrico and Bruni, Francesco and Donnini, Claudia and Vassilev, Alex and He, Langping and Blakely, Emma L and Griffin, Helen and Santibanez-Koref, Mauro and Bindoff, Laurence A and Ferrero, Ileana and Chinnery, Patrick F and McFarland, Robert and Maraia, Richard J and Taylor, Robert W
PLoS Genetics, ISSN 1553-7390, 2014, Volume 10, Issue 6, p. e1004424
Identifying the genetic basis for mitochondrial diseases is technically challenging given the size of the mitochondrial proteome and the heterogeneity of... 
Mitochondrial Diseases - genetics | Schizosaccharomyces pombe Proteins - genetics | Saccharomyces cerevisiae - genetics | Electron Transport - genetics | Humans | Cells, Cultured | Sulfurtransferases - genetics | Male | Electron Transport Complex IV - genetics | Cytosol | RNA - genetics | Schizosaccharomyces - genetics | DNA, Mitochondrial - genetics | Mitochondria - genetics | Alkyl and Aryl Transferases - genetics | RNA, Mitochondrial | RNA, Transfer - genetics | Saccharomyces cerevisiae - enzymology | Female | Schizosaccharomyces - enzymology | Protein Biosynthesis - genetics | Cytochrome-c Oxidase Deficiency - genetics | Enzymes | Phosphorylation | Neuromuscular diseases | Disease | Genes | Mitochondrial DNA | Experiments | Defects | Proteins | Protein synthesis | Efficiency | Mutation | Crystal structure
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