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Immunity, ISSN 1074-7613, 02/2011, Volume 34, Issue 2, pp. 213 - 223
Type I interferon (IFN) is a common therapy for autoimmune and inflammatory disorders, yet the mechanisms of action are largely unknown. Here we showed that... 
FAMILIAL MEDITERRANEAN FEVER | MULTIPLE-SCLEROSIS | CASPASE-1 | HOST-DEFENSE | INNATE | CRYSTALS | RECOMBINANT INTERLEUKIN-1 | MICE | BACTERIAL-INFECTION | IMMUNOLOGY | RECEPTOR ANTAGONIST | Interleukin-1 - genetics | Inflammasomes - metabolism | STAT1 Transcription Factor - deficiency | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Monocytes - metabolism | Monocytes - immunology | Interleukin-10 - physiology | Interleukin-1 - biosynthesis | Interferon-beta - therapeutic use | Interferon Type I - biosynthesis | STAT3 Transcription Factor - physiology | Candida albicans - physiology | Interferon Type I - physiology | Caspase 1 - physiology | Candidiasis - immunology | Carrier Proteins - physiology | Peritonitis - etiology | STAT1 Transcription Factor - physiology | Poly I-C - pharmacology | Disease Susceptibility | Mice, Inbred C57BL | Peritonitis - immunology | STAT1 Transcription Factor - genetics | Gene Expression Regulation - drug effects | Animals | Candidiasis - etiology | Caspase 1 - genetics | Caspase 1 - deficiency | Interferon Type I - genetics | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Apoptosis Regulatory Proteins - physiology | Cells, Cultured - metabolism | Mice | Interferon Inducers - pharmacology | Multiple Sclerosis - drug therapy | Interferon | Infections | Cytokines | Viral infections | Molecular weight | Immune system
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2015, Volume 11, Issue 3, p. e1005088
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2011, Volume 186, Issue 4, pp. 2529 - 2534
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2015, Volume 11, Issue 3
  MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) family member CIITA, which is recruited to SXY enhancers of MHCII promoters via... 
Datasets | Antigens | Genes | Colleges & universities | Logos | Experiments | Deoxyribonucleic acid--DNA | Recruitment
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2011, Volume 186, Issue 4, pp. 2529 - 2534
Although the importance of the NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome in health and disease is well appreciated, a precise... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2012, Volume 188, Issue 8, pp. 3820 - 3828
Nucleotide-binding oligomerization domain-like receptors (NLRs) are intracellular proteins involved in innate-driven inflammatory responses. The function of... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 8/1994, Volume 126, Issue 4, pp. 1059 - 1068
Bcl-2 is a mitochondrial- and perinuclear-associated protein that prolongs the lifespan of a variety of cell types by interfering with programmed cell death... 
T lymphocytes | Complementary DNA | Neurons | Cell death | Cell lines | Fibroblasts | Amino acids | Cells | Apoptosis | Truncation
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/1999, Volume 274, Issue 15, pp. 9962 - 9968
We have previously reported on the death effector domain containing E8 gene product from equine herpesvirus-a, designated FLICE inhibitory protein (v-FLIP),... 
CYTOCHROME-C | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADAPTER | SEQUENCE | CASPASES | RECEPTOR | DEATH | PROTEINS | MYD88 | JNK/SAPK ACTIVATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1992, Volume 89, Issue 17, pp. 8215 - 8219
Journal Article