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Journal of Immunological Methods, ISSN 0022-1759, 06/2019
Plasma cells (PCs) secrete antibodies and play an essential role in protective immunity, but also in pathogenesis of antibody-mediated diseases.... 
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 5, pp. 1410 - 1419.e13
Background Recurrent bacterial and fungal infections, eczema, and increased serum IgE levels characterize patients with the hyper-IgE syndrome (HIES). Known... 
Allergy and Immunology | glycosylation | Hyper-IgE syndrome | signal transducer and activator of transcription 3 | phosphoglucomutase 3 | Staphylococcus aureus | dedicator of cytokinesis 8 | INFECTIONS | DOCK8 | PRIMARY IMMUNODEFICIENCIES | IMMUNOLOGY | IDENTIFICATION | DEFICIENCY | ALLERGY | DISEASE | CONGENITAL DISORDERS | LINKAGE ANALYSIS | MUTASE | Job Syndrome - immunology | Cell Proliferation | Job Syndrome - genetics | T-Lymphocytes - enzymology | Humans | Genetic Diseases, Inborn - genetics | Immunoglobulin E | Infant | Male | Mutation, Missense | Job Syndrome - enzymology | Adult | Female | Child | Tunisia | Genetic Linkage | Phosphoglucomutase - metabolism | Genetic Diseases, Inborn - immunology | Glycosylation | Chromosomes, Human, Pair 6 - genetics | Homozygote | Chromosomes, Human, Pair 6 - metabolism | Genetic Diseases, Inborn - enzymology | T-Lymphocytes - immunology | Phosphoglucomutase - immunology | Immunity - genetics | Phosphoglucomutase - genetics | Amino Acid Substitution | Enzymes | Polysaccharides | Molecular genetics | Stem cells | Physiological aspects | Mycoses | Genetic aspects | Cellular signal transduction | Disease susceptibility | Genetic transcription | Proteins | Signal transduction | Cell growth | Polypeptides | Disease | Values | Mutation | Tetanus | Kinases | Chromosomes | Index Medicus | Abridged Index Medicus | T-Lymphocytes | Genetic Diseases, Inborn | Chromosomes, Human, Pair 6 | Immunity | Phosphoglucomutase | Life Sciences | Immunology | Job Syndrome | PGM3 | STAT3 | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Immunology in the medical area
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 8, pp. 3324 - 3329
Lymphocytes mediate cytotoxicity by polarized release of the contents of cytotoxic granules toward their target cells. Here, we have studied the role of the... 
T lymphocytes | K562 cells | Cytokines | Calcium | Lymphocytes | B lymphocytes | Cell lines | Cytotoxicity | Natural killer cells | Exocytosis | Perforin | Lytic granules | Cytotoxic lymphocytes | Primary immunodeficiency | cytotoxic lymphocytes | CHANNEL FUNCTION | perforin | NATURAL-KILLER-CELLS | OPERATED CA2+ ENTRY | MEDIATED CYTOTOXICITY | MULTIDISCIPLINARY SCIENCES | FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | LYTIC GRANULE EXOCYTOSIS | MICE LACKING | ACTIVATED T-CELLS | lytic granules | MICROTUBULE-ORGANIZING CENTER | primary immunodeficiency | IMMUNOLOGICAL SYNAPSE | T-Lymphocytes, Cytotoxic - immunology | Chemokine CCL4 - biosynthesis | Humans | Calcium - immunology | Killer Cells, Natural - pathology | Cell Degranulation - immunology | ORAI1 Protein | Calcium Channels - immunology | Interleukins - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | Cytokines - biosynthesis | Interferon-gamma - biosynthesis | Cytotoxicity, Immunologic | Physiological aspects | Calcium channels | T cells | Cell death | Molecules | Protein synthesis | Toxicity | Cells | Index Medicus | Polarization | CD8 antigen | Effector cells | Interleukin 12 | Lymphocytes T | Leukocytes | Interleukin 15 | Orai1 protein | Calcium influx | Interleukin 18 | Cell activation | Degranulation | gamma -Interferon | Granules | Macrophage inflammatory protein | Chemokines | Tumor necrosis factor- alpha | Biological Sciences
Journal Article
Haematologica, ISSN 0390-6078, 12/2010, Volume 95, Issue 12, pp. 2080 - 2087
Background Familial hemophagocytic lymphohistiocytosis is a genetic disorder of lymphocyte cytotoxicity that usually presents in the first two years of life... 
Mutations | Familial hemophagocytic lymphohistiocytosis | UNC13D | STXBP2 | LINKED LYMPHOPROLIFERATIVE DISEASE | COMMON VARIABLE IMMUNODEFICIENCY | ADULT-ONSET | BARR-VIRUS INFECTION | MUNC13-4 | DEFICIENCY | NKT CELL-DEVELOPMENT | familial hemophagocytic lymphohistiocytosis | mutations | SYNTAXIN-11 | PERFORIN GENE-MUTATIONS | HEMATOLOGY | GENOTYPE-PHENOTYPE | Immunoglobulin G - blood | Humans | Child, Preschool | Flow Cytometry | Killer Cells, Natural - immunology | Adult | Immunologic Deficiency Syndromes - immunology | Lymphohistiocytosis, Hemophagocytic - genetics | Child | Lymphohistiocytosis, Hemophagocytic - immunology | Munc18 Proteins - genetics | Immunologic Deficiency Syndromes - complications | RNA Splice Sites - genetics | Membrane Proteins - genetics | Gene Frequency | Cells, Cultured | Cell Degranulation - immunology | Killer Cells, Natural - physiology | Lymphohistiocytosis, Hemophagocytic - complications | B-Lymphocytes - immunology | Adolescent | Alleles | K562 Cells | Cell Line, Tumor | Mutation | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic - immunology | Common variable immunodeficiency | Prognosis | CD8 antigen | X chromosome | Chronic infection | Cytotoxicity | Hypogammaglobulinemia | Lymphocytes T | Cell activation | Interleukin 2 | Lymphocytes | Natural killer cells | Encephalitis | Immunological memory | Memory cells | Liver diseases | stem cell transplantation | Immunodeficiency | Histiocytosis | Lymphoma | Lymphocytes B | Obstructive lung disease | Degranulation | Differentiation | Lymphocytosis | Index Medicus | Original
Journal Article
Journal Article
Blood, ISSN 0006-4971, 10/2011, Volume 118, Issue 17, pp. 4620 - 4629
Journal Article
Blood, ISSN 0006-4971, 04/2013, Volume 121, Issue 15, pp. 2943 - 2951
Journal Article