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Nature Cell Biology, ISSN 1465-7392, 01/2013, Volume 15, Issue 1, pp. 61 - 71
Journal Article
Molecular Therapy, ISSN 1525-0016, 10/2005, Volume 12, Issue 4, pp. 763 - 771
Journal Article
Current Biology, ISSN 0960-9822, 03/2015, Volume 25, Issue 6, pp. 679 - 689
Journal Article
Journal Article
Journal Article
American Journal of Human Genetics, ISSN 0002-9297, 01/2008, Volume 82, Issue 1, p. 73
Familial primary localized cutaneous amyloidosis (FPLCA) is an autosomal-dominant disorder associated with chronic skin itching and deposition of epidermal... 
Cytokines | Genes | Genetics | Skin | Mutation | Medical disorders
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2004, Volume 9, Issue S1, pp. S64 - S64
  Immune responses against an introduced transgene are a potential risk in many gene replacement strategies to treat genetic disease. Thus we have developed a... 
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2004, Volume 9, Issue S1, pp. S91 - S91
  Gene therapy for Duchenne muscular dystrophy has so far not been successful because of the difficulty in achieving efficient and permanent gene transfer to... 
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2004, Volume 9, Issue S1, pp. S15 - S15
  Haemophilia B arises from mutations in the factor IX gene. Its treatment in humans, by recombinant protein substitution, is expensive thus limiting its... 
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2004, Volume 9, pp. S15 - S15
Journal Article
Development (Cambridge), ISSN 0950-1991, 03/2018, Volume 145, Issue 5, pp. dev159467 - dev159467
Animal cells are thought to sense mechanical forces via the transcriptional co-activators YAP (or YAP1) and TAZ (or WWTR1), the sole Drosophila homolog of... 
Hippo pathway | Cell shape | Yorkie | Mechanosensing | Drosophila | TISSUE-GROWTH | GROWTH-CONTROL | ACTIVATION | PROTEIN | YORKIE PHOSPHORYLATION | CELL-PROLIFERATION | DEVELOPMENTAL BIOLOGY | APICAL-DOMAIN SIZE | KIBRA | SIGNALING PATHWAY | TUMOR-SUPPRESSOR PATHWAY | Drosophila melanogaster - embryology | Stress, Mechanical | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Mechanotransduction, Cellular - physiology | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Cell Nucleus - metabolism | Gene Expression Regulation, Developmental | Imaginal Discs - embryology | Trans-Activators - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Wings, Animal - embryology | Animals, Genetically Modified | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Protein Transport - genetics | Transcription Factors - metabolism | Wings, Animal - metabolism | Animals | Embryo, Nonmammalian | Imaginal Discs - metabolism | Trans-Activators - metabolism | Drosophila Proteins - genetics | Body Patterning - genetics | Cell culture | Transcription factors | Transcription | Epithelial cells | Epithelium | Kinases | Nuclear transport | Mammalian cells | Yes-associated protein | Warts | Signal transduction | Insects | Transcription activation | Physiology | Mechanical stimuli | Localization | Cytoplasm | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 9, pp. e24484 - e24484
The stem cells of the small intestine are multipotent: they give rise, via transit-amplifying cell divisions, to large numbers of columnar absorptive cells... 
PROGENITOR CELLS | MATH1 | INNER-EAR | INHIBITION | EPITHELIAL-CELLS | IN-VIVO | BIOLOGY | GENE-EXPRESSION | NOTCH | ATONAL HOMOLOG 1 | DIFFERENTIATION | Immunohistochemistry | Cell Cycle - genetics | Male | Intracellular Signaling Peptides and Proteins - metabolism | Stem Cells - cytology | Stem Cells - metabolism | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | In Situ Hybridization | Basic Helix-Loop-Helix Transcription Factors - metabolism | Female | Membrane Proteins - metabolism | Cell Differentiation - physiology | Intracellular Signaling Peptides and Proteins - genetics | Models, Theoretical | Basic Helix-Loop-Helix Transcription Factors - genetics | Membrane Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Intestine, Small - cytology | Cell Cycle - physiology | Mice | In Vitro Techniques | Analysis | Stem cells | Cell cycle | Laboratories | Colorectal cancer | Homeostasis | Stem cell transplantation | Mucus | Absorptivity | Metastasis | Small intestine | Proteins | Histopathology | Allografts | Cell fate | Rodents | Localization | Divisions | Medical research | Goblet cells | Cell division | Paneth cells | Gene expression | Signaling | Insects | Ligands | Notch protein | Cycle time | Data processing | Mathematical models | Differentiation | Index Medicus
Journal Article