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Journal of Investigative Dermatology, ISSN 0022-202X, 09/2019, Volume 139, Issue 9, pp. S324 - S324
Journal Article
by O'Connor, James P. B and Aboagye, Eric O and Adams, Judith E and Aerts, Hugo J. W. L and Barrington, Sally F and Beer, Ambros J and Boellaard, Ronald and Bohndiek, Sarah E and Brady, Michael and Brown, Gina and Buckley, David L and Chenevert, Thomas L and Clarke, Laurence P and Collette, Sana and Cook, Gary J and deSouza, Nandita M and Dickson, John C and Dive, Caroline and Evelhoch, Jeffrey L and Faivre-Finn, Corinne and Gallagher, Ferdia A and Gilbert, Fiona J and Gillies, Robert J and Goh, Vicky and Griffiths, John R and Groves, Ashley M and Halligan, Steve and Harris, Aian L and Hawkes, David J and Hoekstra, Otto S and Huang, Erich P and Hutton, Brian F and Jackson, Edward F and Jayson, Gordon C and Jones, Anew and Koh, Dow-Mu and Lacombe, Denis and Lambin, Philippe and Lassau, Nathalie and Leach, Martin O and Lee, Ting-Yim and Leen, Edward L and Lewis, Jason S and Liu, Yan and Lythgoe, Mark F and Manoharan, Prakash and Maxwell, Ross J and Miles, Kenneth A and Morgan, Bruno and Morris, Steve and Ng, Tony and Padhani, Anwar R and Parker, Geoff J. M and Partridge, Mike and Pathak, Arvind P and Peet, Anew C and Punwani, Shonit and Reynolds, Anew R and Robinson, Simon P and Shankar, Lalitha K and Sharma, Ricky A and Soloviev, Dmitry and Stroobants, Sigrid and Sullivan, Daniel C and Taylor, Stuart A and Tofts, Paul S and Tozer, Gillian M and van Herk, Marcel and Walker-Samuel, Simon and Wason, James and Williams, Kaye J and Workman, Paul and Yankeelov, Thomas E and Brindle, Kevin M and McShane, Lisa M and Jackson, Alan and Waterton, John C
Nature reviews. Clinical oncology, ISSN 1759-4774, 2017, Volume 14, Issue 3, pp. 169 - 186
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 05/2015, Volume 42, Issue 6, p. 831
  3'-Deoxy-3'-^sup 18^F-fluorothymidine (FLT) positron emission tomography (PET) has limited utility in abdominal imaging due to high physiological hepatic... 
Pancreatic cancer | Positrons | Tomography | Disease management | Metastasis
Journal Article
American Heart Journal, ISSN 0002-8703, 2010, Volume 160, Issue 5, pp. 785 - 794.e10
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Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 5399 - 5399
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Journal Article
European Journal of Cancer, ISSN 0959-8049, 2016, Volume 56, pp. 69 - 76
Abstract Studies to identify predictive biomarkers can be carried out in isogenic cancer cell lines, which enable interrogation of the effect of a specific... 
Hematology, Oncology and Palliative Medicine | MEK | Isogenic | Biomarker | PI3K | Combination | DRUG-SENSITIVITY | ORALLY BIOAVAILABLE INHIBITOR | RAS | KINASE | MUTANT CANCERS | HUMAN CANCER-CELLS | IDENTIFICATION | POTENT | ONCOLOGY | COLORECTAL-CANCER | GROWTH | TOR Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Time Factors | Colorectal Neoplasms - drug therapy | Biomarkers, Tumor - metabolism | Female | Antineoplastic Agents - pharmacology | Biomarkers, Tumor - antagonists & inhibitors | MAP Kinase Kinase Kinases - antagonists & inhibitors | Colorectal Neoplasms - enzymology | MAP Kinase Kinase Kinases - metabolism | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Animals | Class I Phosphatidylinositol 3-Kinases | Signal Transduction - drug effects | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Mutation | Colorectal Neoplasms - pathology | Usage | Genetic aspects | Colorectal cancer | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81763
Combined targeting of the MAPK and PI3K signalling pathways in cancer may be necessary for optimal therapeutic activity. To support clinical studies of... 
CARCINOMA-CELLS | POSITRON-EMISSION-TOMOGRAPHY | PATHWAY | BAD | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | KINASE | GROWTH | TRANSCRIPTION | PROLIFERATION | GDC-0941 | Neoplasm Transplantation | Diphenylamine - pharmacology | Humans | Phosphatidylinositol 3-Kinases - metabolism | Positron-Emission Tomography | Diphenylamine - agonists | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Diphenylamine - analogs & derivatives | Heterografts | Colorectal Neoplasms - drug therapy | Female | Sulfonamides - agonists | Benzamides - pharmacology | Phosphorylation - drug effects | MAP Kinase Kinase Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - metabolism | Dideoxynucleosides - pharmacology | Antiviral Agents - pharmacology | Colorectal Neoplasms - enzymology | Indazoles - agonists | Colorectal Neoplasms - diagnostic imaging | MAP Kinase Kinase Kinases - metabolism | Sulfonamides - pharmacology | Drug Synergism | Indazoles - pharmacology | Radiography | Animals | Mice, Nude | Cell Line, Tumor | Benzamides - agonists | Mice | Medicine, Experimental | Medical research | PET imaging | Health aspects | Colorectal cancer | Tumors | Drugs | Phosphorylation | Animal models | Emission analysis | Colorectal carcinoma | Clinical trials | AKT protein | Kinases | Cancer therapies | Medical schools | Bearing | Proteins | Signal transduction | Cell cycle | Xenografts | Tomography | Drug interaction | Bioindicators | Inhibition | Medical imaging | Effectiveness | Invasiveness | MEK inhibitors | Positron emission | Extracellular signal-regulated kinase | MAP kinase | Pharmacology | Bioavailability | 1-Phosphatidylinositol 3-kinase | Signaling | Inhibitors | Emission measurements | Biomarkers | Positron emission tomography | Cancer
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