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1. Full Text Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial
by Tashkin, Donald P, Prof and Roth, Michael D, Prof and Clements, Philip J, Prof and Furst, Daniel E, Prof and Khanna, Dinesh, Prof and Kleerup, Eric C, Prof and Goldin, Jonathan, Prof and Arriola, Edgar, PharmD and Volkmann, Elizabeth R, MD and Kafaja, Suzanne, MD and Silver, Richard, Prof and Steen, Virginia, Prof and Strange, Charlie, Prof and Wise, Robert, Prof and Wigley, Fredrick, Prof and Mayes, Maureen, Prof and Riley, David J, Prof and Hussain, Sabiha, MD and Assassi, Shervin, MD and Hsu, Vivien M, MD and Patel, Bela, MD and Phillips, Kristine, MD and Martinez, Fernando, Prof and Golden, Jeffrey, Prof and Connolly, M Kari, Prof and Varga, John, Prof and Dematte, Jane, Prof and Hinchcliff, Monique E, MD and Fischer, Aryeh, MD and Swigris, Jeffrey, DO and Meehan, Richard, MD and Theodore, Arthur, Prof and Simms, Robert, Prof and Volkov, Suncica, MD and Schraufnagel, Dean E, Prof and Scholand, Mary Beth, MD and Frech, Tracy, MD and Molitor, Jerry A, Prof and Highland, Kristin, MD and Read, Charles A, Prof and Fritzler, Marvin J, Prof and Kim, Grace Hyun J, PhD and Tseng, Chi-Hong, PhD and Elashoff, Robert M, Prof and Sclerodema Lung Study II Investigators and Sclerodema Lung Study II
The lancet respiratory medicine, ISSN 2213-2600, 2016, Volume 4, Issue 9, pp. 708 - 719
Pulmonary/Respiratory | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Lung Diseases, Interstitial - etiology | Cyclophosphamide - administration & dosage | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | Lung - physiopathology | Lung Diseases, Interstitial - drug therapy | Disease Progression | Scleroderma, Systemic - complications | Scleroderma, Systemic - physiopathology | Adult | Female | Aged | Lung Diseases, Interstitial - physiopathology | Respiratory Function Tests | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Index Medicus
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2. Full Text 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative
by Hoogen, F.H.J. van den and Khanna, D and Fransen, J and Johnson, S.R and Baron, M and Tyndall, A and Matucci-Cerinic, M and Naden, R.P and Medsger, T.A., Jr and Carreira, P.E and Riemekasten, G and Clements, P.J and Denton, C.P and Distler, O and Allanore, Y and Furst, D.E and Gabrielli, A and Mayes, M.D and Laar, J.M. van and Seibold, J.R and Czirjak, L and Steen, V.D and Inanc, M and Kowal-Bielecka, O and Muller-Ladner, U and Valentini, G and Veale, D.J and Vonk, M.C and Walker, U.A and Chung, L and Collier, D.H and Csuka, M.E and Fessler, B.J and Guiducci, S and Herrick, A and Hsu, V.M and Jimenez, S and Kahaleh, B and Merkel, P.A and Sierakowski, S and Silver, R.M and Simms, R.W and Varga, J and Pope, J.E
Arthritis and rheumatism, ISSN 0004-3591, 2013, Volume 65, Issue 11, pp. 2737 - 2747
Lung Diseases, Interstitial - etiology | Reproducibility of Results | Scleroderma, Systemic - classification | United States | Autoantibodies - blood | Europe | Humans | Middle Aged | Familial Primary Pulmonary Hypertension | Male | Raynaud Disease - etiology | Scleroderma, Systemic - diagnosis | Telangiectasis - etiology | Scleroderma, Limited - diagnosis | Scleroderma, Systemic - complications | Sensitivity and Specificity | Adult | Female | Aged | Scleroderma, Limited - complications | Hypertension, Pulmonary - etiology | Scleroderma, Limited - classification | Systemic scleroderma | Identification and classification | Scleroderma (Disease) | Drug therapy | Classification | Rheumatology | Index Medicus | Abridged Index Medicus
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3. Full Text Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis
by Mayes, Maureen D and Bossini-Castillo, Lara and Gorlova, Olga and Martin, José Ezequiel and Zhou, Xiaodong and Chen, Wei V and Assassi, Shervin and Ying, Jun and Tan, Filemon K and Arnett, Frank C and Reveille, John D and Guerra, Sandra and Teruel, María and Carmona, Francisco David and Gregersen, Peter K and Lee, Annette T and López-Isac, Elena and Ochoa, Eguzkine and Carreira, Patricia and Simeón, Carmen Pilar and Castellví, Iván and González-Gay, Miguel Ángel and Ortego-Centeno, Norberto and Ríos, Raquel and Callejas, José Luis and Navarrete, Nuria and García Portales, Rosa and Camps, María Teresa and Fernández-Nebro, Antonio and González-Escribano, María F and Sánchez-Román, Julio and García-Hernández, Francisco José and Castillo, María Jesús and Aguirre, María Ángeles and Gómez-Gracia, Inmaculada and Fernández-Gutiérrez, Benjamín and Rodríguez-Rodríguez, Luis and Vicente, Esther and Andreu, José Luis and Fernández de Castro, Mónica and García de la Peña, Paloma and López-Longo, Francisco Javier and Martínez, Lina and Fonollosa, Vicente and Espinosa, Gerard and Tolosa, Carlos and Pros, Anna and Rodríguez Carballeira, Mónica and Narváez, Francisco Javier and Rubio Rivas, Manel and Ortiz Santamaría, Vera and Díaz, Bernardino and Trapiella, Luis and Freire, María del Carmen and Sousa, Adrián and Egurbide, María Victoria and Fanlo Mateo, Patricia and Sáez-Comet, Luis and Díaz, Federico and Hernández, Vanesa and Beltrán, Emma and Román-Ivorra, José Andrés and Grau, Elena and Alegre Sancho, Juan José and Blanco García, Francisco J and Oreiro, Natividad and Fernández Sueiro, Luis and Zhernakova, Alexandra and Padyukov, Leonid and Alarcón-Riquelme, Marta and Wijmenga, Cisca and Brown, Matthew and Beretta, Lorenzo and Riemekasten, Gabriela and Witte, Torsten and Hunzelmann, Nicolas and Kreuter, Alexander and Distler, Jörg H.W and Voskuyl, Alexandre E and Schuerwegh, Annemie J and Hesselstrand, Roger and Nordin, Annika and Airó, Paolo and Lunardi, Claudio and Shiels, Paul and van Laar, Jacob M and Herrick, Ariane and Worthington, Jane and Denton, Christopher and Wigley, Fredrick M and Hummers, Laura K and Varga, John and Hinchcliff, Monique E and Baron, Murray and Hudson, Marie and Pope, Janet E and Furst, Daniel E and Khanna, Dinesh and Phillips, Kristin and Schiopu, Elena and ... and the Spanish Scleroderma Group and Spanish Scleroderma Grp and Spanish Scleroderma Group
American journal of human genetics, ISSN 0002-9297, 01/2014, Volume 94, Issue 1, pp. 47 - 61
RHEUMATOID-ARTHRITIS | FUNCTIONAL POLYMORPHISM | DNASE-GAMMA | JAPANESE POPULATION | PRIMARY BILIARY-CIRRHOSIS | DISEASE | LUPUS-ERYTHEMATOSUS | FOLLOW-UP | GENETIC RISK-FACTOR | GENOME-WIDE ASSOCIATION | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Microtubule-Associated Proteins - genetics | Humans | Male | Genetic Loci | HLA Antigens - genetics | Case-Control Studies | Microchip Analytical Procedures | Female | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Risk Factors | Scleroderma, Systemic - genetics | Genotype | Logistic Models | Proto-Oncogene Proteins - genetics | Chromosomes, Human, Pair 11 - genetics | Interleukin-12 Subunit p35 - genetics | Linkage Disequilibrium | Carrier Proteins - genetics | DEAD-box RNA Helicases - genetics | Endodeoxyribonucleases - genetics | Autophagy-Related Protein 5 | Alleles | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 3 - genetics | Immunogenetics | Systemic scleroderma | Scleroderma (Disease) | Physiological aspects | Genetic aspects | Disease susceptibility | Research | Gene expression | Genotype & phenotype | Antigens | Genetics | Amino acids | Autoimmune diseases | Genomics | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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4. Full Text Cyclophosphamide versus Placebo in Scleroderma Lung Disease
by Tashkin, Donald P and Elashoff, Robert and Clements, Philip J and Goldin, Jonathan and Roth, Michael D and Furst, Daniel E and Arriola, Edgar and Silver, Richard and Strange, Charlie and Bolster, Marcy and Seibold, James R and Riley, David J and Hsu, Vivien M and Varga, John and Schraufnagel, Dean E and Theodore, Arthur and Simms, Robert and Wise, Robert and Wigley, Fredrick and White, Barbara and Steen, Virginia and Read, Charles and Mayes, Maureen and Parsley, Ed and Mubarak, Kamal and Connolly, M. Kari and Golden, Jeffrey and Olman, Mitchell and Fessler, Barri and Rothfield, Naomi and Metersky, Mark and Scleroderma Lung Study Res Grp and Scleroderma Lung Study Research Group
The New England journal of medicine, ISSN 0028-4793, 06/2006, Volume 354, Issue 25, pp. 2655 - 2666
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Bronchoalveolar Lavage Fluid - immunology | Male | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Vital Capacity - drug effects | Leukopenia - chemically induced | Aged, 80 and over | Adult | Female | Lung Diseases, Interstitial - physiopathology | Autoimmune Diseases - drug therapy | Double-Blind Method | Administration, Oral | Treatment Outcome | Scleroderma, Systemic - immunology | Lung Diseases, Interstitial - drug therapy | Lung Diseases, Interstitial - immunology | Regression Analysis | Immunosuppressive Agents - adverse effects | Aged | Respiratory Function Tests | Scleroderma, Systemic - drug therapy | Systemic scleroderma | Drug therapy | Lung diseases | Scleroderma (Disease) | Quality of life | Hypertension | Lungs | Scleroderma | Raynaud disease | Mortality | Index Medicus | Abridged Index Medicus
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5. Full Text Antinuclear antibody-negative systemic sclerosis
by Salazar, Gloria A., MD and Assassi, Shervin, MD, MS and Wigley, Fredrick, MD and Hummers, Laura, MD and Varga, John, MD and Hinchcliff, Monique, MD and Khanna, Dinesh, MD, MS and Schiopu, Elena, MD and Phillips, Kristine, MD, PhD and Furst, Daniel E., MD and Steen, Virginia, MD and Baron, Murray, MD and Hudson, Marie, MD and Taillefer, Suzanne S., PhD and Pope, Janet, MD, MPH and Jones, Niall, MD and Docherty, Peter, MD and Khalidi, Nader A., MD and Robinson, David, MD and Simms, Robert W., MD and Silver, Richard M., MD and Frech, Tracy M., MD, MS and Fessler, Barri J., MD, MSPH and Molitor, Jerry A., MD, PhD and Fritzler, Marvin J., MD, PhD and Segal, Barbara M., MD and Al-Kassab, Firas, MD and Perry, Marilyn, CCRP and Yang, Jeremy, BA and Zamanian, Sara, MD and Reveille, John D., MD and Arnett, Frank C., MD and Pedroza, Claudia, PhD and Mayes, Maureen D., MD, MPH
Seminars in arthritis and rheumatism, ISSN 0049-0172, 2015, Volume 44, Issue 6, pp. 680 - 686
Rheumatology | Vasculopathy | ANA | Negative | Scleroderma | Antinuclear antibody | Systemic sclerosis | Life Sciences & Biomedicine | Science & Technology | Antibodies, Antinuclear - immunology | Humans | Middle Aged | Male | Lung - physiopathology | Skin Ulcer - etiology | Scleroderma, Systemic - immunology | Case-Control Studies | Pulmonary Diffusing Capacity | Malabsorption Syndromes - etiology | Telangiectasis - etiology | Scleroderma, Systemic - complications | Scleroderma, Systemic - physiopathology | Sex Factors | Adult | Female | Retrospective Studies | Kidney Diseases - etiology | Hypertension, Pulmonary - etiology | Pulmonary Fibrosis - etiology | Medical colleges | Autoantibodies | Systemic scleroderma | Scleroderma (Disease) | Index Medicus
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6. Full Text Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease
by Distler, Oliver and Highland, Kristin B and Gahlemann, Martina and Azuma, Arata and Fischer, Aryeh and Mayes, Maureen D and Raghu, Ganesh and Sauter, Wiebke and Girard, Mannaig and Alves, Margarida and Clerisme-Beaty, Emmanuelle and Stowasser, Susanne and Tetzlaff, Kay and Kuwana, Masataka and Maher, Toby M and SENSCIS Trial Investigators
The New England journal of medicine, ISSN 0028-4793, 06/2019, Volume 380, Issue 26, pp. 2518 - 2528
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Enzyme Inhibitors - adverse effects | Lung Diseases, Interstitial - etiology | Double-Blind Method | Administration, Oral | Humans | Middle Aged | Male | Diarrhea - chemically induced | Enzyme Inhibitors - therapeutic use | Lung Diseases, Interstitial - drug therapy | Disease Progression | Vital Capacity | Indoles - adverse effects | Scleroderma, Systemic - complications | Adult | Female | Indoles - therapeutic use | Lung Diseases, Interstitial - physiopathology | Scleroderma, Systemic - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Drug therapy | Sclerosis | Tyrosine | Mycophenolic acid | Sensitivity analysis | Lung diseases | Rheumatology | Oral administration | Clinical trials | Diarrhea | Patients | Pulmonary hypertension | Pulmonary fibrosis | Computed tomography | Systemic sclerosis | Technical communication | Fibrosis | Skin | Scleroderma | Protein-tyrosine kinase | Index Medicus | Abridged Index Medicus
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7. Full Text Development of pulmonary hypertension in a high-risk population with systemic sclerosis in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) cohort study
by Hsu, Vivien M., MD and Chung, Lorinda, MD, MS and Hummers, Laura K., MD and Wigley, Fredrick, MD and Simms, Robert, MD and Bolster, Marcy, MD and Silver, Rick, MD and Fischer, Aryeh, MD and Hinchcliff, Monique E., MD, MS and Varga, John, MD and Goldberg, Avram Z., MD and Derk, Chris T., MD and Schiopu, Elena, MD and Khanna, Dinesh, MD and Shapiro, Lee S., MD and Domsic, Robyn T., MD and Medsger, Thomas, MD and Mayes, Maureen D., MD, MPH and Furst, Daniel, MD and Csuka, Mary E., MD and Molitor, Jerry A., MD and Alkassab, Firas, MD and Steen, Virginia D., MD
Seminars in arthritis and rheumatism, ISSN 0049-0172, 2014, Volume 44, Issue 1, pp. 55 - 62
Rheumatology | Systemic | Pulmonary arterial hypertension | Registry | Scleroderma | Life Sciences & Biomedicine | Science & Technology | Prospective Studies | Humans | Middle Aged | Male | Risk | Raynaud Disease - etiology | Scleroderma, Systemic - complications | Adult | Female | Registries | Aged | Hypertension, Pulmonary - etiology | Longitudinal Studies | Systemic scleroderma | Pulmonary hypertension | Scleroderma (Disease) | Index Medicus
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8. Full Text Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma
by Sullivan, Keith M and Goldmuntz, Ellen A and Keyes-Elstein, Lynette and McSweeney, Peter A and Pinckney, Ashley and Welch, Beverly and Mayes, Maureen D and Nash, Richard A and Crofford, Leslie J and Eggleston, Barry and Castina, Sharon and Griffith, Linda M and Goldstein, Julia S and Wallace, Dennis and Craciunescu, Oana and Khanna, Dinesh and Folz, Rodney J and Goldin, Jonathan and St. Clair, E. William and Seibold, James R and Phillips, Kristine and Mineishi, Shin and Simms, Robert W and Ballen, Karen and Wener, Mark H and Georges, George E and Heimfeld, Shelly and Hosing, Chitra and Forman, Stephen and Kafaja, Suzanne and Silver, Richard M and Griffing, Leroy and Storek, Jan and LeClercq, Sharon and Brasington, Richard and Csuka, Mary E and Bredeson, Christopher and Keever-Taylor, Carolyn and Domsic, Robyn T and Kahaleh, M. Bashar and Medsger, Thomas and Furst, Daniel E and SCOT Study Investigators
The New England journal of medicine, ISSN 0028-4793, 01/2018, Volume 378, Issue 1, pp. 35 - 47
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Follow-Up Studies | Infections - etiology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Kaplan-Meier Estimate | Male | Transplantation, Autologous | Hematopoietic Stem Cell Transplantation - mortality | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Young Adult | Disease-Free Survival | Scleroderma, Systemic - therapy | Scleroderma, Systemic - mortality | Adolescent | Hematopoietic Stem Cell Transplantation - adverse effects | Intention to Treat Analysis | Adult | Female | Immunosuppressive Agents - adverse effects | Aged | Transplantation Conditioning | Scleroderma, Systemic - drug therapy | Treatment outcome | Care and treatment | Systemic scleroderma | Analysis | Patient outcomes | Scleroderma (Disease) | Stem cells | Transplantation | CD34 antigen | Medical research | Autografts | Kidneys | Transplants & implants | Toxicity | Hypersensitivity | Stem cell transplantation | Immunosuppressive agents | Hemopoiesis | Cyclophosphamide | Immunosuppression | Infectious diseases | Systemic sclerosis | Renal failure | Skin | Scleroderma | Heart diseases | Kidney transplantation | Index Medicus | Abridged Index Medicus
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