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PLoS Pathogens, ISSN 1553-7366, 02/2015, Volume 11, Issue 2
  The recent emergence of a novel H7N9 influenza A virus (IAV) causing severe human infections in China raises concerns about a possible pandemic. The lack of... 
Datasets | Pandemics | Lymphocytes | Influenza | Viruses | Population | Cytotoxicity | Infections | Vaccines
Journal Article
American Journal of Physiology, ISSN 1040-0605, 04/2013, Volume 304, Issue 7, p. L481
  During influenza virus infection, it is unclear how much alveolar cell loss can be tolerated before the host succumbs to the disease. We sought to define... 
Cellular biology | Influenza | Viruses | Physiology | Viral infections | Cells
Journal Article
Nature Immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1266 - 1276
Highly pathogenic avian influenza viruses pose a continuing global threat. Current vaccines will not protect against newly evolved pandemic viruses. The... 
CELLS | H5N1 | TRANSMISSION | ACTIVATION | PEPTIDE ARRAYS | MEMORY | CONSEQUENCES | IMMUNOLOGY | AID | NEUTRALIZATION | CYTOTOXICITY | Orthomyxoviridae Infections - prevention & control | TOR Serine-Threonine Kinases - metabolism | Influenza A Virus, H5N1 Subtype - physiology | Immunoglobulin Class Switching - immunology | Immunoglobulin M - immunology | Orthomyxoviridae - classification | Host-Pathogen Interactions - immunology | Mechanistic Target of Rapamycin Complex 1 | Orthomyxoviridae - immunology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Flow Cytometry | T-Lymphocytes - metabolism | Female | Immunoglobulin Class Switching - drug effects | Adaptive Immunity - immunology | Immunosuppressive Agents - pharmacology | B-Lymphocytes - metabolism | Cell Line | Antibody Formation - immunology | Mice, Inbred C57BL | Influenza A Virus, H3N2 Subtype - immunology | Sirolimus - pharmacology | Mice, Knockout | TOR Serine-Threonine Kinases - immunology | Animals | B-Lymphocytes - immunology | Influenza A Virus, H5N1 Subtype - immunology | Survival Analysis | Antibodies, Viral - immunology | T-Lymphocytes - immunology | Influenza A Virus, H3N2 Subtype - physiology | Mice | Orthomyxoviridae Infections - virology | Orthomyxoviridae - physiology | Orthomyxoviridae Infections - immunology | Multiprotein Complexes - immunology | Influenza viruses | Prevention | Immune response | Protein kinases | Health aspects | Testing
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, p. 288
Characterizing the TCR[alpha] and TCR[beta] chains expressed by T cells responding to a given pathogen or underlying autoimmunity helps in the development of... 
Autoimmunity | Physiological aspects | Antigen receptors, T cell | Receptors | Research | T cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2011, Volume 108, Issue 35, p. 14602
It is currently thought that T cells with specificity for self-peptide/MHC (pMHC) ligands are deleted during thymic development, thereby preventing... 
Antigens | Genotype & phenotype | Peptides | Rodents | T cell receptors
Journal Article
Journal Article
Nature immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1266 - 1276
Highly pathogenic avian influenza viruses pose a continuing global threat. Current vaccines will not protect against novel pandemic viruses. Creating... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 08/2011, Volume 108, Issue 35, pp. 14602 - 14607
It is currently thought that T cells with specificity for self-peptide/MHC (pMHC) ligands are deleted during thymic development, thereby preventing... 
Autoimmunity | T-cell receptor | Major histocompatibility complex | Immunoregulation | Avidity | Foxp3 protein | Lymphocytes T | CD4 antigen | Thymus
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 08/2011, Volume 108, Issue 35, p. 14602
tetramer | Treg | tolerance | T-cell receptor I transgenic 
Major histocompatibility complex | Physiological aspects | Research | T cells | Immunity
Journal Article
Antiviral Research, ISSN 0166-3542, 05/2009, Volume 82, Issue 2, pp. A33 - A33
Journal Article
ACS Infectious Diseases, ISSN 2373-8227, 09/2015, Volume 1, Issue 9, pp. 435 - 442
Although differences in the rate of virus fusion and budding from the host cell membrane have been correlated with pathogenicity, no systematic study of the... 
influenza | plasmalogens | virion | infectious disease | phospholipids | lipidomics | membrane lipid composition | INFECTIOUS DISEASES | CHEMISTRY, MEDICINAL | FATTY-ACID SYNTHESIS | ENTRY | CHOLESTEROL | GLYCOPROTEINS | SPHINGOLIPIDS | QUANTITATIVE-ANALYSIS | A VIRUS | MEMBRANE-FUSION | EPITHELIAL-CELLS | INFECTION
Journal Article