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life sciences & biomedicine (34) 34
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by Waszak, Sebastian M and Northcott, Paul A and Buchhalter, Ivo and Robinson, Giles W and Sutter, Christian and Groebner, Susanne and Grund, Kerstin B and Brugières, Laurence and Jones, David T W and Pajtler, Kristian W and Morrissy, A Sorana and Kool, Marcel and Sturm, Dominik and Chavez, Lukas and Ernst, Aurelie and Brabetz, Sebastian and Hain, Michael and Zichner, Thomas and Segura-Wang, Maia and Weischenfeldt, Joachim and Rausch, Tobias and Mardin, Balca R and Zhou, Xin and Baciu, Cristina and Lawerenz, Christian and Chan, Jennifer A and Varlet, Pascale and Guerrini-Rousseau, Lea and Fults, Daniel W and Grajkowska, Wiesława and Hauser, Peter and Jabado, Nada and Ra, Young-Shin and Zitterbart, Karel and Shringarpure, Suyash S and De La Vega, Francisco M and Bustamante, Carlos D and Ng, Ho-Keung and Perry, Arie and MacDonald, Tobey J and Hernáiz Driever, Pablo and Bendel, Anne E and Bowers, Daniel C and McCowage, Geoffrey and Chintagumpala, Murali M and Cohn, Richard and Hassall, Timothy and Fleischhack, Gudrun and Eggen, Tone and Wesenberg, Finn and Feychting, Maria and Lannering, Birgitta and Schüz, Joachim and Johansen, Christoffer and Andersen, Tina V and Röösli, Martin and Kuehni, Claudia E and Grotzer, Michael and Kjaerheim, Kristina and Monoranu, Camelia M and Archer, Tenley C and Duke, Elizabeth and Pomeroy, Scott L and Shelagh, Redmond and Frank, Stephan and Sumerauer, David and Scheurlen, Wolfram and Ryzhova, Marina V and Milde, Till and Kratz, Christian P and Samuel, David and Zhang, Jinghui and Solomon, David A and Marra, Marco and Eils, Roland and Bartram, Claus R and von Hoff, Katja and Rutkowski, Stefan and Ramaswamy, Vijay and Gilbertson, Richard J and Korshunov, Andrey and Taylor, Michael D and Lichter, Peter and Malkin, David and Gajjar, Amar and Korbel, Jan O and Pfister, Stefan M and Sahlgrenska akademin and Institute of Clinical Sciences, Department of Pediatrics and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, Avdelningen för pediatrik and Sahlgrenska Academy
The lancet oncology, ISSN 1470-2045, 06/2018, Volume 19, Issue 6, pp. 785 - 798
Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Medicine, Experimental | Genetic research | Clinical trials | Medical research | Medulloblastoma | Index Medicus | fanconi-anemia | breast-cancer | tp53 | somatic mutations | mutation | subgroups | palb2 | brain-tumors | children | childhood-cancer | Cancer and Oncology | landscape | Cancer och onkologi
Journal Article
Journal Article
Pediatric blood & cancer, ISSN 1545-5009, 11/2020, Volume 67, Issue 11, pp. e28594 - n/a
Driver mutations in the CTNNB1 gene (encoding β‐catenin) are a hallmark of sporadic hepatoblastoma (HBL). Our results show that CTNNB1 circulating tumour DNA... 
hepatoblastoma | CTNNB1 | ctDNA | liquid biopsy | Liver cancer | CTNNB1 gene | Biomarkers | Tumors | Index Medicus
Journal Article
British journal of cancer, ISSN 1532-1827, 01/2020, Volume 122, Issue 5, pp. 680 - 691
... Xie1, Robyn E. Lukeis6, Murray D. Norris1,7, Michelle Haber1, Geoffrey B. McCowage8, Greg M. Arndt5, Toby N. Trahair 1,2,9 and Jamie I. Fletcher 1,2 BACKGROUND... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus
Journal Article
Human gene therapy, ISSN 1043-0342, 08/2018, Volume 29, Issue 8, pp. 874 - 885
Gene transfer targeting hematopoietic stem cells (HSC) in children has shown sustained therapeutic benefit in the treatment of genetic diseases affecting the... 
Research Articles | clinical trial | gene therapy | cancer | pediatric brain tumors | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Genetic Therapy | Tumor Suppressor Proteins - therapeutic use | Guanine - analogs & derivatives | DNA Modification Methylases - therapeutic use | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Brain Neoplasms - genetics | DNA Repair Enzymes - therapeutic use | Hematopoietic Stem Cell Transplantation | Male | Hematopoietic Stem Cells - metabolism | Brain Neoplasms - drug therapy | DNA Modification Methylases - genetics | Drug Resistance, Neoplasm - genetics | Temozolomide - administration & dosage | Tumor Suppressor Proteins - genetics | Female | Child | Guanine - administration & dosage | Brain | Toxicity | Brain tumors | Brain cancer | Central nervous system | Clinical trials | Lymphocytes T | Drug resistance | DNA repair | Hematopoietic stem cells | Guanine | O6-methylguanine-DNA methyltransferase | Proteins | Infusion | Bone marrow | Children | Conditioning | Drug dosages | Genetic modification | Deoxyribonucleic acid--DNA | Immune system | Genetic disorders | Chemoprotection | Leukodystrophy | Medical treatment | Feasibility studies | Patients | Hemopoiesis | Chemotherapy | Adrenoleukodystrophy | Glioma | Stem cells | Temozolomide | Gene therapy | Tumors | Index Medicus
Journal Article
Pediatric blood & cancer, ISSN 1545-5009, 11/2020, Volume 67, Issue 11
Driver mutations in theCTNNB1gene (encoding beta-catenin) are a hallmark of sporadic hepatoblastoma (HBL). Our results show thatCTNNB1circulating tumour DNA... 
Pediatrics | Life Sciences & Biomedicine | Hematology | Oncology | Science & Technology
Journal Article
Pediatric pulmonology, ISSN 1099-0496, 08/2019, Volume 54, Issue 11, pp. 1821 - 1829
Journal Article
The Annals of thoracic surgery, ISSN 0003-4975, 03/2019, Volume 107, Issue 3, pp. e183 - e185
Primary cardiac tumors in children are uncommon and rarely demand surgical intervention. We report a malignant tumor arising from the aortic root in a... 
Cardiac & Cardiovascular Systems | Respiratory System | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Surgery | Science & Technology | Pediatrics | Heart valve diseases | Children | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
Cancer gene therapy, ISSN 0929-1903, 09/2020
Chimeric Antigen Receptor (CAR) T-cell therapy, as an approved treatment option for patients with B cell malignancies, demonstrates that genetic modification... 
Life Sciences & Biomedicine | Oncology | Genetics & Heredity | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus
Journal Article
Journal Article
JMIR research protocols, ISSN 1929-0748, 08/2018, Volume 7, Issue 8, pp. e168 - e168
Adolescent and young adults with cancer are at increased risk of psychosocial difficulties relative to their healthy peers. Current models of inpatient... 
Psychosocial | Telehealth | Adolescent | Young adult | Videoconferencing | Psychological assessment | Cancer
Journal Article
Journal of neuro-oncology, ISSN 1573-7373, 11/2018, Volume 140, Issue 3, pp. 717 - 725
Journal Article