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Proceedings of the National Academy of Sciences, ISSN 0027-8424, 05/2007, Volume 104, Issue 20, pp. 8520 - 8525
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 06/2014, Volume 89, Issue 4, pp. 536 - 544
Activation of T-type Ca channels contributes to nociceptive signaling by facilitating action potential bursting and modulation of membrane potentials during... 
Dorsal root ganglion | T-type Ca2+ channels | Neuropathic pain | Nociceptive pain | ACTIVATION | SODIUM | ANTAGONIST | INJURY | ALLODYNIA | MODEL | SENSORY NEURONS | POTENT | GENE | TARGETS | PHARMACOLOGY & PHARMACY | Calcium Channel Blockers - adverse effects | Humans | Calcium Channel Blockers - therapeutic use | Neuralgia - metabolism | Biological Availability | Male | Nociceptive Pain - drug therapy | Peripheral Nerves - drug effects | Dose-Response Relationship, Drug | Heterocyclic Compounds, 2-Ring - adverse effects | Nociceptive Pain - metabolism | Calcium Channels, T-Type - metabolism | Calcium Channels, T-Type - chemistry | Heterocyclic Compounds, 2-Ring - therapeutic use | Peripheral Nerves - cytology | Behavior, Animal - drug effects | Calcium Channels, T-Type - genetics | Peripheral Nerves - metabolism | Disease Models, Animal | Recombinant Proteins - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Chronic Pain - drug therapy | Cells, Cultured | Rats | Recombinant Proteins - chemistry | Heterocyclic Compounds, 2-Ring - pharmacokinetics | Calcium Channel Blockers - pharmacology | Sulfonamides - pharmacology | Blood-Brain Barrier - drug effects | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | Neuralgia - drug therapy | Sulfonamides - pharmacokinetics | Blood-Brain Barrier - metabolism | Heterocyclic Compounds, 2-Ring - pharmacology | Nerve Tissue Proteins - metabolism | Chronic Pain - metabolism | Animals | Sulfonamides - therapeutic use | Sulfonamides - adverse effects | Calcium Channel Blockers - pharmacokinetics | Care and treatment | Pain
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 5310 - 9
Psoriasis is an immune-mediated inflammatory skin disease that affects millions worldwide. Studying immune cells involved in psoriasis pathogenesis is... 
ORIGINS | DENDRITIC CELLS | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | MONOCYTES | IL12B | MECHANISMS | ASSOCIATION | T-CELLS | LESIONS | Flow cytometry | Monocytes | Animal models | Psoriasis | Skin diseases | Interleukin 23 | Tumor necrosis factor-α | Macrophages | Interleukin 17
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2019, Volume 139, Issue 5, p. S123
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 01/2014, Volume 111, Issue 2, pp. 394 - 404
N-, T- and P/Q-type voltage-gated Ca2+ channels are critical for regulating neurotransmitter release and cellular excitability and have been implicated in... 
N-type Ca | Spinal cord | channels | T-type Ca | P/Q-type Ca | Neuropathic pain | N-TYPE | PHYSIOLOGY | SENSITIVE CALCIUM-CHANNEL | NEUROTRANSMITTER RELEASE | DORSAL-ROOT GANGLIA | NERVE INJURY | DIABETIC-NEUROPATHY | NEUROSCIENCES | SENSORY NEURONS | DOSE-DEPENDENT ANTINOCICEPTION | neuropathic pain | OMEGA-CONOTOXIN | T-type Ca2+ channels | P/Q-type Ca2+ channels | spinal cord | N-type Ca2+ channels | HORN NEURONAL RESPONSES | Azabicyclo Compounds - pharmacology | Leucine - pharmacology | Anesthetics - therapeutic use | Calcium Channel Blockers - therapeutic use | Anesthetics - pharmacology | Leucine - therapeutic use | Male | Administration, Cutaneous | Peripheral Nerves - drug effects | Action Potentials | Dose-Response Relationship, Drug | Peripheral Nerves - physiology | Spinal Nerves - drug effects | Neurons - physiology | Nociception - drug effects | Inhibitory Concentration 50 | Azabicyclo Compounds - therapeutic use | Neuralgia - physiopathology | Neurons - drug effects | Anesthetics - administration & dosage | Leucine - analogs & derivatives | Spinal Nerves - physiology | Injections, Spinal | Rats | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Neuralgia - drug therapy | Hyperalgesia - physiopathology | Animals | Hyperalgesia - drug therapy | Calcium Channel Blockers - administration & dosage
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 1 - 8
Foxp3(+) regulatory T cells (Tregs) represent a major fraction of skin resident T cells. Although normally protective, Tregs have been shown to produce... 
MAINTENANCE | MECHANISMS | DIFFERENTIATION | FOXP3 | MULTIDISCIPLINARY SCIENCES
Journal Article
Pain, ISSN 0304-3959, 2011, Volume 152, Issue 5, pp. 1165 - 1172
Despite the increasing interest in TRPA1 channel as a pain target, its role in cold sensation and body temperature regulation is not clear; the efficacy and... 
Blockade | Pain | Noxious cold | TRPA1 | Temperature regulation | Temperature sensation | ACTIVATION | TRPV1 | NEUROSCIENCES | SENSORY NEURONS | CLINICAL NEUROLOGY | THERMOREGULATION | INFLAMMATION | ION-CHANNEL | ANESTHESIOLOGY | HYPERALGESIA | TRPM8 | CONTRIBUTES | NOCICEPTION | Calcium Channels - metabolism | Body Temperature - drug effects | Calcium - metabolism | Humans | Male | Pain - metabolism | Drug Interactions | Pain - genetics | Transient Receptor Potential Channels - metabolism | Calcitonin Gene-Related Peptide - metabolism | Calcium Channels - genetics | Isothiocyanates - pharmacology | Disease Models, Animal | Body Temperature Regulation - physiology | Rats | Rats, Sprague-Dawley | Sensation - drug effects | Pain - physiopathology | Transient Receptor Potential Channels - genetics | Ganglia, Spinal - pathology | Mice | Body Temperature Regulation - genetics | Transient Receptor Potential Channels - antagonists & inhibitors | Sensation - physiology | Magnetic Resonance Imaging - methods | Oximes - therapeutic use | Tritium | Body Temperature - physiology | Heart Rate - drug effects | TRPV Cation Channels - metabolism | Pain - drug therapy | Reaction Time - drug effects | Heart Rate - physiology | Inhibitory Concentration 50 | Body Temperature Regulation - drug effects | Blood Pressure - drug effects | Blood Pressure - physiology | Neurons - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Cells, Cultured | Nerve Tissue Proteins - genetics | Cold Temperature - adverse effects | TRPV Cation Channels - genetics | Hyperalgesia - physiopathology | Nerve Tissue Proteins - metabolism | Pain Measurement - methods | Animals | Hyperalgesia - drug therapy | TRPA1 Cation Channel | Oximes - pharmacology | Sensory Thresholds - drug effects
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2016, Volume 59, Issue 10, pp. 4926 - 4947
Journal Article