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Journal Article
Aging Cell, ISSN 1474-9718, 01/2020, Volume 19, Issue 1, pp. e13056 - n/a
Transient plasma membrane disruptions (PMD) occur in osteocytes with in vitro and in vivo loading, initiating mechanotransduction. The goal here was to... 
mechanical loading | skeleton | bone | aging | osteocyte | mechanotransduction
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 05/2018, Volume 29, Issue 5, pp. 284 - 286
Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in show that β-aminoisobutyric acid... 
MICE | ENDOCRINOLOGY & METABOLISM | Muscles | Aminoisobutyric Acids | Osteocytes
Journal Article
JOURNAL OF ENDOCRINOLOGY, ISSN 0022-0795, 10/2019, Volume 243, Issue 1, pp. 15 - 26
Osteoporosis, low bone mass that increases fracture susceptibility, affects approximately 75 million individuals in the United States, Europe and Japan, with... 
CELLS | OXIDATIVE STRESS | fat mass | MOUSE | OSTEOGENIC DIFFERENTIATION | bone | DELETION | FUMARIC-ACID ESTERS | NRF2 | CANCELLOUS BONE | mesenchymal stem cells | ENDOCRINOLOGY & METABOLISM | MICE | monomethyfumarate | CARDIOPROTECTION | ovariectomy
Journal Article
Experimental Gerontology, ISSN 0531-5565, 02/2020, Volume 130, p. 110818
Aging is a progressive process associated with declining tissue function over time. Kynurenine, an oxidized metabolite of the essential amino acid tryptophan... 
Energy metabolism | Kynurenine | Osteoblast | Aging | Bone | Histone deacetylase 3 | Marrow fat | MARROW ADIPOSE-TISSUE | SERUM TRYPTOPHAN | MECHANISMS | GERIATRICS & GERONTOLOGY | DIET | TYROSINE | FAT | PATHWAY METABOLISM | DIFFERENTIATION | BONE MASS
Journal Article
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, ISSN 1942-0900, 10/2019, Volume 2019, pp. 1 - 9
The cellular and molecular mechanisms underlying loss of muscle mass with age (sarcopenia) are not well-understood; however, heterochronic parabiosis... 
MORTALITY | SKELETAL-MUSCLE | RESPONSES | CELLS | ARYL-HYDROCARBON RECEPTOR | OLDER-ADULTS | SARCOPENIA | IDENTIFICATION | CELL BIOLOGY | Oxidative stress | Young adults | Gene expression | Metabolism | Atrophy | Proteins | Sarcopenia | Musculoskeletal system | Hypotheses | Ostomy | Metabolites | Aging | Population | Physiology | Drug dosages | Age | Endocrinology
Journal Article
Cytokine, ISSN 1043-4666, 11/2019, Volume 123, p. 154783
Musculoskeletal disorders are the leading cause of disability worldwide; two of the most prevalent of which are osteoporosis and sarcopenia. Each affect... 
Muscle | Stromal cell-derived D factor-1 (CXCL12) | Bone | RHEUMATOID-ARTHRITIS | MARROW | CHEMOKINE RECEPTOR CXCR4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | OSTEOGENIC DIFFERENTIATION | SATELLITE CELLS | IMMUNOLOGY | OSTEOCLAST PRECURSORS | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | ENDOTHELIAL GROWTH-FACTOR | MORPHOGENETIC PROTEIN-2 | HEMATOPOIETIC STEM
Journal Article
JOURNAL OF ENDOCRINOLOGY, ISSN 0022-0795, 10/2019, Volume 243, Issue 1, pp. 27 - 42
Journal Article
Journal of biological chemistry, ISSN 0021-9258, 12/2018, Volume 293, pp. 19001 - 19011
Ezh2 is a histone methyltransferase that suppresses osteoblast maturation and skeletal development. We evaluated the roleof Ezh2 in chondrocyte lineage... 
Journal Article
Journal Article
Current osteoporosis reports, ISSN 1544-1873, 12/2019, Volume 17, Issue 6, pp. 438 - 445
The development of adiposity in the bone marrow, known as marrow adipose tissue (MAT), is often associated with musculoskeletal frailty. Glucocorticoids, which... 
Journal Article