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by Cohen, Ezra E W and Soulières, Denis and Le Tourneau, Christophe and Dinis, José and Licitra, Lisa and Ahn, Myung-Ju and Soria, Ainara and Machiels, Jean-Pascal and Mach, Nicolas and Mehra, Ranee and Burtness, Barbara and Zhang, Pingye and Cheng, Jonathan and Swaby, Ramona F and Harrington, Kevin J and Acosta-Rivera, Mirelis and Adkins, Douglas R and Aghmesheh, Morteza and Ahn, Myung-Ju and Airoldi, Mario and Aleknavicius, Eduardas and Al-Farhat, Yousuf and Algazi, Alain P and Almokadem, Salah and Alyasova, Anna and Bauman, Jessica R and Benasso, Marco and Berrocal, Alfonso and Bray, Victoria and Burtness, Barbara Ann and Caponigro, Francesco and Castro, Ana and Cescon, Terrence P and Chan, Kelvin and Chaudhry, Arvind and Chauffert, Bruno and Cohen, Ezra and Csoszi, Tibor and De Boer, J.P and Delord, Jean-Pierre and Dietz, Andreas and Dinis, Jose and Dupuis, Charlotte and Digue, Laurence and Erfan, Jozsef and Escobar Alvarez, Yolanda and Evans, Mererid and Fidler, Mary Jo and Forster, Martin David and Friesland, Signe and Ganti, Apar K and Geoffrois, Lionnel and Grant, Cliona and Gruenwald, Viktor and Harrington, Kevin and Hoffmann, Thomas and Horvai, Geza and Inciura, Arturas and Jang, Raymond and Jankowska, Petra and Jimeno, Antonio and Joseph, Mano and Juarez Ramiro, Alejandro and Karaszewska, Boguslawa and Kawecki, Andrzej and Keilholz, Ulrich and Keller, Ulrich and Kim, Sung-Bae and Kocsis, Judit and Kotecki, Nuria and Kozloff, Mark F and Lambea, Julio and Landherr, Laszlo and Lantsukhay, Yuri and Lazarev, Sergey Alexandrovich and Lee, Lip Way and Le Tourneau, Christophe and Licitra, Lisa and Lifirenko, Igor Dmitrievich and Mach, Nicolas and Martincic, Danko and Matorin, Oleg Vladmirovhich and McGrath, Margaret and Machiels, Jean-Pascal and Mehra, Ranee and Misiukiewicz, Krzysztof and Morris, John C and Mufazalov, Fagim Fanisovich and Niu, Jiaxin and Pamoorthy Srinivasan, Devraj and Perez Segura, Pedro and Rauch, Daniel and Ribeiro, Maria Leonor and Rodriguez, Cristina and Rolland, Frederic and Russo, Antonio and Ruzsa, Agnes and Sanches, Frederico and Shin, Sang-Won and Shtiveland, Mikhail and ... and KEYNOTE-040 investigators and Keynote-040 Investigators
The Lancet, ISSN 0140-6736, 01/2019, Volume 393, Issue 10167, pp. 156 - 167
There are few effective treatment options for patients with recurrent or metastatic head-and-neck squamous cell carcinoma. Pembrolizumab showed antitumour... 
CRITERIA | TRIAL | MEDICINE, GENERAL & INTERNAL | NIVOLUMAB | CANCER | CHEMOTHERAPY | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Docetaxel - adverse effects | Humans | Middle Aged | Squamous Cell Carcinoma of Head and Neck - pathology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Cetuximab - therapeutic use | Cetuximab - adverse effects | Docetaxel - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Squamous Cell Carcinoma of Head and Neck - drug therapy | Female | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Drug Administration Schedule | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Disease Progression | Head and Neck Neoplasms - pathology | Methotrexate - adverse effects | Squamous Cell Carcinoma of Head and Neck - secondary | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cetuximab - administration & dosage | Methotrexate - administration & dosage | Aged | Methotrexate | Squamous cell carcinoma | Metastasis | Therapy | Toxicity | Perforation | Clinical trials | Oncology | Cancer therapies | Metastases | Skin cancer | Anticancer properties | Pembrolizumab | Randomization | Motivation | Platinum | Neck | Safety | Medical treatment | Fatigue | Hypothyroidism | Survival | Patients | Chemotherapy | Interactive systems | Large intestine | Head and neck cancer | Ligands | Tumors
Journal Article
by Ripke, Stephan and Sanders, Alan R and Kendler, Kenneth S and Levinson, Douglas F and Sklar, Pamela and Holmans, Peter A and Lin, Dan-Yu and Duan, Jubao and Ophoff, Roel A and Aneassen, Ole A and Scolnick, Edward and Cichon, Sven and St Clair, David and Corvin, Aiden and Gurling, Hugh and Werge, Thomas and Rujescu, Dan and Blackwood, Douglas H. R and Pato, Carlos N and Malhotra, Anil K and Purcell, Shaun and Dudbridge, Frank and Neale, Benjamin M and Rossin, Lizzy and Visscher, Peter M and Posthuma, Danielle and Ruderfer, Douglas M and Fanous, Ayman and Stefansson, Hreinn and Steinberg, Stacy and Mowry, Bryan J and Golimbet, Vera and de Hert, Marc and Jönsson, Erik G and Bitter, István and Pietiläinen, Olli P. H and Collier, David A and Tosato, Sarah and Agartz, Ingrid and Albus, Margot and Alexander, Madeline and Amdur, Richard L and Amin, Farooq and Bass, Nicholas and Bergen, Sarah E and Black, Donald W and Børglum, Anders D and Brown, Matthew A and Bruggeman, Richard and Buccola, Nancy G and Byerley, William F and Cahn, Wiepke and Cantor, Rita M and Carr, Vaughan J and Catts, Stanley V and Choudhury, Khalid and Cloninger, C. Robert and Cormican, Paul and Craddock, Nicholas and Danoy, Patrick A and Datta, Susmita and de Haan, Lieuwe and Demontis, Ditte and Dikeos, Dimitris and Djurovic, Srdjan and Donnelly, Peter and Donohoe, Gary and Duong, Linh and Dwyer, Sarah and Fink-Jensen, Anders and Freedman, Robert and Freimer, Nelson B and Friedl, Marion and Georgieva, Lyudmila and Giegling, Ina and Gill, Michael and Glenthøj, Birte and Godard, Stephanie and Hamshere, Marian and Hansen, Mark and Hansen, Thomas and Hartmann, Annette M and Henskens, Frans A and Hougaard, David M and Hultman, Christina M and Ingason, Anés and Jablensky, Assen V and Jakobsen, Klaus D and Jay, Maurice and Jürgens, Gesche and Kahn, René S and Keller, Matthew C and Kenis, Gunter and Kenny, Elaine and Kim, Yunjung and Kirov, George K and Konnerth, Heike and Konte, Bettina and Krabbendam, Lydia and Krasucki, Robert and ... and Schizophrenia Psychiat Genome-Wide and Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium and The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 10, pp. 969 - 976
Journal Article
by Garcia-Closas, M and Chatterjee, N and Malats, N and Wu, X and Figueroa, J.D and Real, F.X and Berg, D.P.G. van den and Matullo, G and Baris, D and Thun, M and Kiemeney, L.A.L.M and Vilneis, P and De Vivo, I and Albanes, D and Purdue, M and Rafnar, T and Hildebrandt, M.A.T and Kiltie, A.E and Cussenot, O and Golka, K and Kumar, R and Taylor, J.A and Mayordomo, J.I and Jacobs, K.B and Kogevinas, M and Hutchinson, A and Wang, Z and Fu, Y and Prokunina-Olsson, L and Burdett, L and Yeager, M and Wheeler, W and Tardon, A and Serra, C and Carrato, A and Garcia-Closas, R and Lloreta, J and Johnson, A and Schwenn, M and Karagas, M.R and Schned, A and Aniole, G.L and Grubb, R and Black, A and Jacobs, E.J and Diver, W.R and Gapstur, S.M and Weinstein, S.J and Virtamo, J and Cortessis, V.K and Gago-Dominguez, M and Pike, M.C and Stern, M.C and Yuan, J.M and Hunter, D.J and McGrath, M and Dinney, C.P and Czerniak, B and Chen, M and Yang, H and Vermeulen, S and Aben, K.K.H and Witjes, J.A and Makkinje, R.R and Sulem, P and Besenbacher, S and Riboli, E and Brennan, P and Panico, S and Navarro, C and Allen, N.E and Bueno-De-Mesquita, H.B and Trichopoulos, D and Caporaso, N and Landi, M.T and Canzian, F and Ljungberg, B and Tjonneland, A and Clavel-Chapelon, F and Bishop, D.T and Teo, M.T and Knowles, M.A and Guarrera, S and Polidoro, S and Ricceri, F and Sacerdote, C and Allione, A and Cancel-Tassin, G and Selinski, S and Hengstler, J.G and Dietrich, H and Fletcher, T and Rudnai, P and Gurzau, E and Koppova, K and Bolick, S.C and Godfrey, A and Xu, Z
Nature genetics, ISSN 1061-4036, 2010, Volume 42, Issue 11, pp. 978 - 984
Journal Article
by Wang, Haidong and Allen, Christine and Bhutta, Zulfiqar A and Casey, Daniel C and Charlson, Fiona J and Chen, Alan Zian and Coggeshall, Megan and Dicker, Daniel J and Ferrari, Alize J and Fitzmaurice, Christina and Forouzanfar, Mohammad H and Fraser, Maya S and Fullman, Nancy and Gething, Peter W and Goldberg, Ellen M and Hay, Simon I and Huynh, Chantal and Johnson, Catherine O and Kassebaum, Nicholas J and Kinfu, Yohannes and Kulikoff, Xie Rachel and Kutz, Michael and Kyu, Hmwe H and Larson, Heidi J and Leung, Janni and Liang, Xiaofeng and Lim, Stephen S and Lind, Margaret and Marquez, Neal and Mensah, George A and Mokdad, Ali H and Mooney, Meghan D and Nsoesie, Elaine and Pigott, David M and Pinho, Christine and Salomon, Joshua A and Sandar, Logan and Silpakit, Naris and Sligar, Amber and Steiner, Caitlyn and Teeple, Stephanie and Troeger, Christopher and VanderZanden, Amelia and Wanga, Valentine and Whiteford, Harvey A and Wolock, Timothy and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abreu, Daisy M X and Abu-Raddad, Laith J and Abyu, Gebre Yitayih and Achoki, Tom and Adelekan, Ademola Lukman and Ademi, Zanfina and Adou, Arsène Kouablan and Afshin, Ashkan and Agardh, Emilie Elisabet and Agarwal, Arnav and Kiadaliri, Aliasghar Ahmad and Ajala, Oluremi N and Akanda, Ali Shafqat and Akinyemi, Rufus Olusola and Akinyemiju, Tomi F and Akseer, Nadia and Alabed, Samer and Alam, Noore K M and Alasfoor, Deena and Aldhahri, Saleh Fahed and Aldridge, Robert William and Alemu, Zewdie Aderaw and Alexander, Lily T and Ali, Raghib and Alkerwi, Ala'a and Allebeck, Peter and Al-Raddadi, Rajaa and Martin, Elena Alvarez and Alvis-Guzman, Nelson and Amegah, Adeladza Kofi and Ammar, Walid and Amrock, Stephen Marc and Andersen, Hjalte H and Anderson, Benjamin O and Anderson, Gregory M and Antonio, Carl Abelardo T and Ärnlöv, Johan and Artaman, Al and Asghar, Rana Jawad and Atique, Suleman and Awasthi, Ashish and Bacha, Umar and Barker-Collo, Suzanne L and Bärnighausen, Till and Basu, Arindam and Basu, Sanjay and Bayou, Yibeltal Tebekaw and Bazargan-Hejazi, Shahrzad and Beardsley, Justin and Beghi, Ettore and Bell, Brent and ... and GBD 2015 Mortality and Causes of Death Collaborators and GBD 015 Mortality and Causes Death and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri and Göteborgs universitet and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin and Gothenburg University and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy and Sahlgrenska akademin and Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics and Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine
Lancet, The, ISSN 0140-6736, 10/2016, Volume 388, Issue 10053, pp. 1459 - 1544
Journal Article