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by Howe, Kerstin and Clark, Matthew D and Torroja, Carlos F and Torrance, James and Berthelot, Camille and Muffato, Matthieu and Collins, John E and Humphray, Sean and McLaren, Karen and Matthews, Lucy and McLaren, Stuart and Sealy, Ian and Caccamo, Mario and Churcher, Carol and Scott, Carol and Barrett, Jeffrey C and Koch, Romke and Rauch, Gerd-Jörg and White, Simon and Chow, William and Kilian, Britt and Quintais, Leonor T and Guerra-Assunção, José A and Zhou, Yi and Gu, Yong and Yen, Jennifer and Vogel, Jan-Hinnerk and Eyre, Tina and Redmond, Seth and Banerjee, Ruby and Chi, Jianxiang and Fu, Beiyuan and Langley, Elizabeth and Maguire, Sean F and Laird, Gavin K and Lloyd, David and Kenyon, Emma and Donaldson, Sarah and Sehra, Harminder and Almeida-King, Jeff and Loveland, Jane and Trevanion, Stephen and Jones, Matt and Quail, Mike and Willey, Dave and Hunt, Adrienne and Burton, John and Sims, Sarah and McLay, Kirsten and Plumb, Bob and Davis, Joy and Clee, Chris and Oliver, Karen and Clark, Richard and Riddle, Clare and Elliott, David and Threadgold, Glen and Harden, Glenn and Ware, Darren and Begum, Sharmin and Mortimore, Beverley and Kerry, Giselle and Heath, Paul and Phillimore, Benjamin and Tracey, Alan and Corby, Nicole and Dunn, Matthew and Johnson, Christopher and Wood, Jonathan and Clark, Susan and Pelan, Sarah and Griffiths, Guy and Smith, Michelle and Glithero, Rebecca and Howden, Philip and Barker, Nicholas and Lloyd, Christine and Stevens, Christopher and Harley, Joanna and Holt, Karen and Panagiotidis, Georgios and Lovell, Jamieson and Beasley, Helen and Henderson, Carl and Gordon, Daria and Auger, Katherine and Wright, Deborah and Collins, Joanna and Raisen, Claire and Dyer, Lauren and Leung, Kenric and Robertson, Lauren and Ambridge, Kirsty and Leongamornlert, Daniel and McGuire, Sarah and Gilderthorp, Ruth and Griffiths, Coline and Manthravadi, Deepa and Nichol, Sarah and Barker, Gary and ...
Nature (London), ISSN 1476-4687, 2013, Volume 496, Issue 7446, pp. 498 - 503
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 373, Issue 3, pp. 232 - 242
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2019, Volume 380, Issue 4, pp. 347 - 357
In a randomized trial of patients with type 2 diabetes, treatment with dapagliflozin, an SGLT2 inhibitor that promotes glucosuria, did not result in a higher... 
MORTALITY | 2013 ACCF/AHA GUIDELINE | MEDICINE, GENERAL & INTERNAL | SELECTIVE SGLT2 INHIBITOR | MANAGEMENT | HEART-FAILURE OUTCOMES | DISEASE | AMERICAN-COLLEGE | ASSOCIATION TASK-FORCE | KIDNEY | EMPAGLIFLOZIN | Cardiovascular Diseases - etiology | Sodium-Glucose Transporter 2 Inhibitors - therapeutic use | Sodium-Glucose Transporter 2 Inhibitors - adverse effects | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Benzhydryl Compounds - adverse effects | Cardiovascular Diseases - mortality | Female | Glucosides - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Benzhydryl Compounds - therapeutic use | Heart Failure - epidemiology | Diabetes Mellitus, Type 2 - complications | Glucosides - adverse effects | Type 2 diabetes | Safety and security measures | Dapagliflozin | Dosage and administration | Drug therapy | Cardiovascular diseases | Risk factors | Heart failure | Myocardial infarction | Cerebral infarction | End-stage renal disease | Heart attacks | Mortality | Diabetes mellitus | Cardiovascular disease | FDA approval | Patients | Glomerular filtration rate | Heart rate | Ischemia | Sodium | Arteriosclerosis | Ketoacidosis | Death | Diabetes | Kidney diseases | Safety | Diabetes mellitus (non-insulin dependent) | Heart diseases | Life Sciences | Food and Nutrition | Animal biology | Cellular Biology | Pharmaceutical sciences | Cardiovascular Diseases | drug therapy | Benzhydryl Compounds | complications | Sodium-Glucose Transporter 2 Inhibitors | Hospitalization | prevention & control | Klinisk medicin | Diabetes Mellitus | etiology | Clinical Medicine | epidemiology | statistics & numerical data | adverse effects | mortality | Type 2 | Heart Failure | therapeutic use | Glucosides
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2018, Volume 379, Issue 7, pp. 633 - 644
In an observational study, patients with type 2 diabetes who had glycated hemoglobin, LDL cholesterol, albuminuria, and blood pressure in target ranges and did... 
MEDICINE, GENERAL & INTERNAL | GLYCEMIA | HYPERGLYCEMIA | MANAGEMENT | DISEASE | MULTIFACTORIAL INTERVENTION | MICROVASCULAR OUTCOMES | FOLLOW-UP | COMPLICATIONS | MELLITUS | ASSOCIATION | Body Mass Index | Glycated Hemoglobin A - analysis | Albuminuria - complications | Cardiovascular Diseases - etiology | Myocardial Infarction - epidemiology | Humans | Middle Aged | Risk Factors | Male | Sweden - epidemiology | Diabetes Mellitus, Type 2 - blood | Smoking - epidemiology | Diabetes Mellitus, Type 2 - mortality | Cardiovascular Diseases - epidemiology | Hypertension - complications | Adult | Female | Hypercholesterolemia - complications | Stroke - epidemiology | Diabetes Mellitus, Type 2 - complications | Cohort Studies | Diabetics | Cardiovascular diseases | Health aspects | Patient outcomes | Risk factors | Myocardial infarction | Cardiac arrhythmia | Heart attacks | Cardiovascular disease | Confidence intervals | Smoking cessation | Hemoglobin | Blood pressure | Diabetes mellitus (non-insulin dependent) | Heart diseases | Age | Heart failure | Cerebral infarction | Stroke | Mortality | Diabetes mellitus | Patients | Low density lipoprotein | Cholesterol | Death | Diabetes | Health risk assessment | Smoking | microvascular | disease | complications | mellitus | association | Klinisk medicin | multifactorial intervention | Clinical Medicine | follow-up | hyperglycemia | outcomes | management | accord randomized-trial | General & Internal Medicine
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2013, Volume 369, Issue 14, pp. 1317 - 1326
Saxagliptin, a new oral antihyperglycemic drug in the DPP-4 inhibitor class, had no effect on the risk of cardiovascular events in patients with type 2... 
no | ALL-CAUSE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | EVENTS | GLUCOSE CONTROL | MICROALBUMINURIA | DISEASE | CLINICAL-USE | PREVENTION | RISK | DEATH | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Adamantane - therapeutic use | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Hypoglycemia - chemically induced | Heart Failure - epidemiology | Diabetes Mellitus, Type 2 - complications | Adamantane - adverse effects | Adamantane - analogs & derivatives | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Dipeptides - therapeutic use | Double-Blind Method | Pancreatitis - epidemiology | Dipeptides - adverse effects | Kaplan-Meier Estimate | Pancreatitis - chemically induced | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Patient outcomes | Dosage and administration | Drug therapy | Heart diseases | Risk factors | Saxagliptin | Myocardial infarction | Cerebral infarction | Heart attacks | Peptidase | Diabetes mellitus | Pancreatitis | Cardiovascular disease | Angina | Patients | Heart rate | Ischemia | Diabetes | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent)
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2017, Volume 377, Issue 24, pp. 2337 - 2348
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2017, Volume 376, Issue 15, pp. 1407 - 1418
Patients with type 1 or type 2 diabetes in Sweden were studied to examine trends in mortality and cardiovascular disease incidence between 1998 and 2014. Both... 
POPULATION | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | THERAPY | HEART-FAILURE | MULTIFACTORIAL INTERVENTION | COMPLICATIONS | PEOPLE | TRENDS | ASSOCIATION | BLOOD-PRESSURE | Cardiovascular Diseases - etiology | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Mortality - trends | Diabetes Mellitus, Type 1 - complications | Sweden - epidemiology | Incidence | Diabetes Mellitus, Type 1 - mortality | Diabetes Mellitus, Type 2 - mortality | Hospitalization - trends | Adolescent | Age of Onset | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Female | Registries | Aged | Diabetes Mellitus, Type 2 - complications | Complications and side effects | Usage | Mortality | Analysis | Distribution | Event history analysis | Diabetes | Cardiovascular diseases | Heart failure | Heart attacks | Diabetes mellitus | Cardiovascular disease | Diabetes mellitus (insulin dependent) | Metabolism | Patients | Coronary artery disease | Studies | Insulin resistance | Death | Trends | Diabetes mellitus (non-insulin dependent) | Heart diseases | Age | Cardiovascular Diseases | Kardiologi | epidemiology | Sweden | Endokrinologi och diabetes | Type 2 | trends | Endocrinology and Diabetes | Type 1 | complications | Hospitalization | Diabetes Mellitus | etiology | Cardiac and Cardiovascular Systems | mortality
Journal Article