Trends in Biochemical Sciences, ISSN 0968-0004, 10/2015, Volume 40, Issue 10, pp. 611 - 622
The vacuolar (H )-ATPases (V-ATPases) are ATP-dependent proton pumps that acidify intracellular compartments and are also present at the plasma membrane. They...
cancer | V-ATPase | proton transport | acidification | membrane traffic | cell signaling | Acidification | Membrane traffic | Cell signaling | Cancer | Proton transport | BREAST-CANCER CELLS | ACTIVATED PROTEIN-KINASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | PH HOMEOSTASIS | SUBUNIT ISOFORMS | MEMBRANE DOMAIN | VACUOLAR H+-ATPASE | SACCHAROMYCES-CEREVISIAE | PROTON PUMP | Proton-Translocating ATPases - metabolism | Animals | Proton-Translocating ATPases - genetics | Humans | Cell Membrane - metabolism | Structure-Activity Relationship | Proton-Translocating ATPases - chemistry | Chemical properties | Proteolysis | Health aspects | Adenosine triphosphatase | Membrane proteins
cancer | V-ATPase | proton transport | acidification | membrane traffic | cell signaling | Acidification | Membrane traffic | Cell signaling | Cancer | Proton transport | BREAST-CANCER CELLS | ACTIVATED PROTEIN-KINASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | PH HOMEOSTASIS | SUBUNIT ISOFORMS | MEMBRANE DOMAIN | VACUOLAR H+-ATPASE | SACCHAROMYCES-CEREVISIAE | PROTON PUMP | Proton-Translocating ATPases - metabolism | Animals | Proton-Translocating ATPases - genetics | Humans | Cell Membrane - metabolism | Structure-Activity Relationship | Proton-Translocating ATPases - chemistry | Chemical properties | Proteolysis | Health aspects | Adenosine triphosphatase | Membrane proteins
Journal Article
Frontiers in Bioscience - Landmark, ISSN 1093-9946, 01/2017, Volume 22, Issue 4, pp. 609 - 622
V-ATPases are ATP-driven proton pumps present in both intracellular and cell surface membranes of eukaryotes that function in many normal and disease...
Regulated trafficking | Control of cellular ph | Regulated assembly | V-ATPase | Review | Control of acidification | Control Of Acidification | PROTEIN-KINASE-A | COATED VESICLE (H+)-ATPASE | YEAST VACUOLAR | SECRETORY INTERCALATED CELLS | IN-VIVO DISSOCIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Control Of Cellular Ph | VACUOLAR H+-ATPASE | PLASMA-MEMBRANE | CELL BIOLOGY | BREAST-CANCER CELLS | Regulated Trafficking | MEDULLARY COLLECTING DUCT | Regulated Assembly | EPIDIDYMAL CLEAR CELLS | Vacuolar Proton-Translocating ATPases - genetics | Humans | Protein Multimerization | Models, Molecular | Mammals | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Protein Transport | Animals | Insect Proteins - chemistry | Vacuolar Proton-Translocating ATPases - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Protein Subunits - chemistry | Insect Proteins - metabolism | Protein Subunits - genetics | Saccharomyces cerevisiae Proteins - chemistry
Regulated trafficking | Control of cellular ph | Regulated assembly | V-ATPase | Review | Control of acidification | Control Of Acidification | PROTEIN-KINASE-A | COATED VESICLE (H+)-ATPASE | YEAST VACUOLAR | SECRETORY INTERCALATED CELLS | IN-VIVO DISSOCIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Control Of Cellular Ph | VACUOLAR H+-ATPASE | PLASMA-MEMBRANE | CELL BIOLOGY | BREAST-CANCER CELLS | Regulated Trafficking | MEDULLARY COLLECTING DUCT | Regulated Assembly | EPIDIDYMAL CLEAR CELLS | Vacuolar Proton-Translocating ATPases - genetics | Humans | Protein Multimerization | Models, Molecular | Mammals | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Protein Transport | Animals | Insect Proteins - chemistry | Vacuolar Proton-Translocating ATPases - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Protein Subunits - chemistry | Insect Proteins - metabolism | Protein Subunits - genetics | Saccharomyces cerevisiae Proteins - chemistry
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 08/2016, Volume 1857, Issue 8, pp. 1213 - 1218
V-ATPases are ATP-driven proton pumps that function within both intracellular compartments and the plasma membrane in a wide array of normal physiological and...
YEAST VACUOLAR | BREAST-CANCER CELLS | BIOPHYSICS | DENDRITIC CELLS | IN-VIVO DISSOCIATION | GLUCOSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBUNIT ISOFORMS | A3 ISOFORM | VACUOLAR H+-ATPASE | PLASMA-MEMBRANE | PROTON PUMP | Vacuolar Proton-Translocating ATPases - genetics | ras Proteins - genetics | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Saccharomyces cerevisiae - genetics | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Multiprotein Complexes - genetics | Mammary Glands, Human - metabolism | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Mechanistic Target of Rapamycin Complex 1 | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | TOR Serine-Threonine Kinases - genetics | Female | Cyclic AMP - metabolism | Protein Subunits - genetics | Cyclic AMP-Dependent Protein Kinases - metabolism | Signal Transduction | Neoplasm Invasiveness | Epithelial Cells - pathology | Mammary Glands, Human - pathology | Cell Line, Tumor | Cell Movement | Amino acids | Metastasis | Dendritic cells | Adenosine triphosphatase | Membrane proteins
YEAST VACUOLAR | BREAST-CANCER CELLS | BIOPHYSICS | DENDRITIC CELLS | IN-VIVO DISSOCIATION | GLUCOSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBUNIT ISOFORMS | A3 ISOFORM | VACUOLAR H+-ATPASE | PLASMA-MEMBRANE | PROTON PUMP | Vacuolar Proton-Translocating ATPases - genetics | ras Proteins - genetics | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Saccharomyces cerevisiae - genetics | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Multiprotein Complexes - genetics | Mammary Glands, Human - metabolism | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Mechanistic Target of Rapamycin Complex 1 | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | TOR Serine-Threonine Kinases - genetics | Female | Cyclic AMP - metabolism | Protein Subunits - genetics | Cyclic AMP-Dependent Protein Kinases - metabolism | Signal Transduction | Neoplasm Invasiveness | Epithelial Cells - pathology | Mammary Glands, Human - pathology | Cell Line, Tumor | Cell Movement | Amino acids | Metastasis | Dendritic cells | Adenosine triphosphatase | Membrane proteins
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 04/2017, Volume 595, Issue 8, pp. 2661 - 2679
Voltage-gated sodium channel Na(V)1.7 is required for acute and inflammatory pain in mice and humans but its significance for visceral pain is unknown. Here we...
SODIUM-CHANNEL NA(V)1.7 | PHYSIOLOGY | RAT | REFERRED HYPERALGESIA | MOUSE | NEURONS | SPINAL-CORD | INFLAMMATORY PAIN | CANCER PAIN | NEUROSCIENCES | IRRITABLE-BOWEL-SYNDROME | CELIAC PLEXUS BLOCK
SODIUM-CHANNEL NA(V)1.7 | PHYSIOLOGY | RAT | REFERRED HYPERALGESIA | MOUSE | NEURONS | SPINAL-CORD | INFLAMMATORY PAIN | CANCER PAIN | NEUROSCIENCES | IRRITABLE-BOWEL-SYNDROME | CELIAC PLEXUS BLOCK
Journal Article
British Journal of Psychiatry, ISSN 0007-1250, 06/2010, Volume 196, Issue 6, pp. 434 - 439
Background There is an ongoing debate about the use of atypical antipsychotics as a first-line treatment for first-episode psychosis. Aims To examine the...
PSYCHIATRY | Choice Behavior - drug effects | Antipsychotic Agents - therapeutic use | Antipsychotic Agents - adverse effects | Humans | Female | Male | Weight Gain - drug effects | Psychotic Disorders - drug therapy | Randomized Controlled Trials as Topic | Discontinued | Neuroleptics | Extrapyramidal system | Schizophrenia | Efficacy | Weight gain | Meta-analysis | Psychosis | Studies | Psychotropic drugs | Side effects | Psychoses | Population | First time | Atypical | Psychiatry | Drug dosages | Review
PSYCHIATRY | Choice Behavior - drug effects | Antipsychotic Agents - therapeutic use | Antipsychotic Agents - adverse effects | Humans | Female | Male | Weight Gain - drug effects | Psychotic Disorders - drug therapy | Randomized Controlled Trials as Topic | Discontinued | Neuroleptics | Extrapyramidal system | Schizophrenia | Efficacy | Weight gain | Meta-analysis | Psychosis | Studies | Psychotropic drugs | Side effects | Psychoses | Population | First time | Atypical | Psychiatry | Drug dosages | Review
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 23, pp. 9113 - 9123
The vacuolar H+-ATPase (V-ATPase) is an ATP-driven proton pump involved in many cellular processes. An important mechanism by which V-ATPase activity is...
YEAST VACUOLAR | BAFILOMYCIN A1 | INFLUENZA-A | RAG GTPASES | MTORC1 ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | ACIDIFICATION | SALIVARY-GLANDS | VACUOLAR H+-ATPASE | PROTON PUMP | AMP-Activated Protein Kinases - metabolism | Signal Transduction | Humans | Protein Multimerization | HEK293 Cells | Glucose - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Enzyme Activation | Proto-Oncogene Proteins c-akt - metabolism | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Editors' Picks | vacuolar ATPase | proton transport | regulated assembly | glucose starvation | AMP-activated kinase (AMPK) | phosphatidylinositide 3-kinase (PI 3-kinase) | Akt PKB
YEAST VACUOLAR | BAFILOMYCIN A1 | INFLUENZA-A | RAG GTPASES | MTORC1 ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | ACIDIFICATION | SALIVARY-GLANDS | VACUOLAR H+-ATPASE | PROTON PUMP | AMP-Activated Protein Kinases - metabolism | Signal Transduction | Humans | Protein Multimerization | HEK293 Cells | Glucose - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Enzyme Activation | Proto-Oncogene Proteins c-akt - metabolism | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Editors' Picks | vacuolar ATPase | proton transport | regulated assembly | glucose starvation | AMP-activated kinase (AMPK) | phosphatidylinositide 3-kinase (PI 3-kinase) | Akt PKB
Journal Article
ASTROPHYSICAL JOURNAL, ISSN 0004-637X, 09/2019, Volume 882, Issue 2
Vibrationally excited states of detected interstellar molecules have been shown to account for a large portion of unidentified spectral lines in observed...
ISM: molecules | HOT CORES | ASTRONOMY & ASTROPHYSICS | ISM: individual objects (NGC 63341) | astrochemistry
ISM: molecules | HOT CORES | ASTRONOMY & ASTROPHYSICS | ISM: individual objects (NGC 63341) | astrochemistry
Journal Article
The Astrophysical Journal, ISSN 1538-4357, 09/2019, Volume 882, Issue 2, p. 118
Journal Article
Physical Review B - Condensed Matter and Materials Physics, ISSN 1098-0121, 06/2013, Volume 87, Issue 22
The spin and orbital ordering in Dy1-xTbxVO3 (x = 0 and 0.2) was studied by measuring x-ray powder diffraction, magnetization, specific heat, and neutron...
YVO3 | PHYSICS, CONDENSED MATTER | TRANSITION-METAL OXIDES
YVO3 | PHYSICS, CONDENSED MATTER | TRANSITION-METAL OXIDES
Journal Article
Physical Review Letters, ISSN 0031-9007, 10/2017, Volume 119, Issue 16, p. 161101
On August 17, 2017 at 12∶41:04 UTC the Advanced LIGO and Advanced Virgo gravitational-wave detectors made their first observation of a binary neutron star...
GAMMA-RAY BURST | MASSES | EQUATION-OF-STATE | PHYSICS, MULTIDISCIPLINARY | ADVANCED LIGO | PULSAR | MERGERS | RADIATION | DENSE MATTER | General Relativity and Quantum Cosmology | Physics | Astrophysics | ASTRONOMY AND ASTROPHYSICS
GAMMA-RAY BURST | MASSES | EQUATION-OF-STATE | PHYSICS, MULTIDISCIPLINARY | ADVANCED LIGO | PULSAR | MERGERS | RADIATION | DENSE MATTER | General Relativity and Quantum Cosmology | Physics | Astrophysics | ASTRONOMY AND ASTROPHYSICS
Journal Article
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Full Text
GW170104: Observation of a 50-Solar-Mass Binary Black Hole Coalescence at Redshift 0.2
Physical Review Letters, ISSN 0031-9007, 06/2017, Volume 118, Issue 22, p. 221101
We describe the observation of GW170104, a gravitational-wave signal produced by the coalescence of a pair of stellar-mass black holes. The signal was measured...
GW150914 | GALACTIC DISTRIBUTION | EVOLUTION | PARAMETER-ESTIMATION | PHYSICS, MULTIDISCIPLINARY | DYNAMICAL FORMATION | LIGO | MASS | MERGERS | COMPACT OBJECT FORMATION | GRAVITATIONAL-WAVE OBSERVATIONS | General Relativity and Quantum Cosmology | Physics | Astrophysics
GW150914 | GALACTIC DISTRIBUTION | EVOLUTION | PARAMETER-ESTIMATION | PHYSICS, MULTIDISCIPLINARY | DYNAMICAL FORMATION | LIGO | MASS | MERGERS | COMPACT OBJECT FORMATION | GRAVITATIONAL-WAVE OBSERVATIONS | General Relativity and Quantum Cosmology | Physics | Astrophysics
Journal Article