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cardiovascular (12) 12
humans (7) 7
cardiac & cardiovascular systems (6) 6
index medicus (6) 6
internal medicine (6) 6
cardiology and cardiovascular medicine (5) 5
electrocardiography (5) 5
cardiomyopathy (4) 4
female (4) 4
male (4) 4
adult (3) 3
aged (3) 3
cardiology (3) 3
disease (3) 3
genetics (3) 3
heart diseases (3) 3
middle aged (3) 3
right-ventricular cardiomyopathy (3) 3
abridged index medicus (2) 2
age factors (2) 2
amorphous polymers (2) 2
analysis (2) 2
anticoagulants (2) 2
arrhythmia (2) 2
arrhythmogenic right ventricular dysplasia - diagnosis (2) 2
arrhythmogenic right ventricular dysplasia - genetics (2) 2
cardiac arrhythmia (2) 2
cardiomyopathy, hypertrophic (2) 2
care and treatment (2) 2
death, sudden, cardiac - etiology (2) 2
diastolic dysfunction (2) 2
dilated cardiomyopathy (2) 2
dysplasia (2) 2
electrocardiogram (2) 2
familial hypertrophic cardiomyopathy (2) 2
gene (2) 2
genetic predisposition to disease (2) 2
genotype (2) 2
medicine & public health (2) 2
mutation (2) 2
plakophilins - genetics (2) 2
prognosis (2) 2
relaxation (2) 2
sudden cardiac death (2) 2
sudden death (2) 2
tachycardia (2) 2
abnormalities (1) 1
activation (1) 1
administration, cutaneous (1) 1
aerobic power (1) 1
age (1) 1
alleles (1) 1
altern (1) 1
am1-bcc model (1) 1
anti-inflammatory agents - administration & dosage (1) 1
anti-inflammatory agents - therapeutic use (1) 1
arrhythmias, cardiac - diagnosis (1) 1
arrhythmias, cardiac - genetics (1) 1
arrhythmogenic right ventricular cardiomyopathy/dysplasia (1) 1
arrhythmogenic right ventricular dysplasia - economics (1) 1
arrhythmogenic right ventricular dysplasia - therapy (1) 1
artificial neural networks (1) 1
arvc (1) 1
behavior (1) 1
biologic control systems (1) 1
biomedical cybernetics (1) 1
bisphenol a-diglycidylether (1) 1
bisphenol-a (1) 1
calorimetry (1) 1
cardiac-arrest (1) 1
cardiomyopathy, dilated - diagnosis (1) 1
cardiomyopathy, dilated - genetics (1) 1
cardiomyopathy, hypertrophic - diagnostic imaging (1) 1
cardiomyopathy, hypertrophic - genetics (1) 1
cardiomyopathy, hypertrophic - physiopathology (1) 1
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cardiovascular diseases - genetics (1) 1
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cardiovascular magnetic-resonance (1) 1
cardiovascular-disease (1) 1
channel (1) 1
chemistry, analytical (1) 1
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chromosome mapping - economics (1) 1
circuito neural (1) 1
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clobetasol - administration & dosage (1) 1
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cohort (1) 1
complications and side effects (1) 1
conduction defect (1) 1
conductivity (1) 1
confidence intervals (1) 1
congestive heart failure (1) 1
constrictive pericarditis (1) 1
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1. Full Text Pioneer in Cardiology: William John McKenna, BA, MD, DSc, FRCP, FMedSci, FESC, FACC
by Taylor, J and McKenna, WJ
CIRCULATION, ISSN 0009-7322, 11/2009, Volume 120, Issue 19, pp. F109 - F111
CARDIAC & CARDIOVASCULAR SYSTEMS | FAMILIAL HYPERTROPHIC CARDIOMYOPATHY | GENE | DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | RIGHT-VENTRICULAR CARDIOMYOPATHY
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2. Full Text Left-Dominant Arrhythmogenic Cardiomyopathy
by Sen-Chowdhry, Srijita, MBBS, MD (Cantab), MRCP and Syrris, Petros, PhD and Prasad, Sanjay K., MD, MRCP and Hughes, Siân E., MBBS, PhD, MRCPath and Merrifield, Robert, PhD and Ward, Deirdre, MBBS, MRCPI and Pennell, Dudley J., MD, FACC and McKenna, William J., MD, DSc, FACC
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 52, Issue 25, pp. 2175 - 2187
Objectives We sought to investigate the clinical-genetic profile of left-dominant arrhythmogenic cardiomyopathy (LDAC). Background In the absence of coronary... 
Cardiovascular | Internal Medicine | sudden death | magnetic resonance imaging | genetics | cardiomyopathy | arrhythmia | electrocardiography | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOVASCULAR MAGNETIC-RESONANCE | DIASTOLIC FUNCTION | DYSPLASIA | DILATED CARDIOMYOPATHY | HYPERTROPHIC CARDIOMYOPATHY | MYOCARDIAL FIBROSIS | DISEASE | ENHANCEMENT | SUDDEN CARDIAC DEATH | RIGHT-VENTRICULAR CARDIOMYOPATHY | Rare earth metals | Tachycardia | Cardiomyopathy | Heart diseases | Histochemistry | Legislators | Medical colleges | Medical imaging equipment
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3. Full Text Role of Genetic Analysis in the Management of Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
by Sen-Chowdhry, Srijita, MBBS, MD, MRCP and Syrris, Petros, BSc, PhD and McKenna, William J., MD, DSc, FRCP, FACC
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2007, Volume 50, Issue 19, pp. 1813 - 1821
Role of Genetic Analysis in the Management of Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Srijita Sen-Chowdhry, Petros Syrris,... 
Cardiovascular | Internal Medicine | DNA Mutational Analysis - economics | Defibrillators, Implantable - economics | Life Style | Prognosis | Age Factors | Transforming Growth Factor beta3 - genetics | Humans | Death, Sudden, Cardiac - prevention & control | Death, Sudden, Cardiac - etiology | Arrhythmogenic Right Ventricular Dysplasia - diagnosis | Arrhythmogenic Right Ventricular Dysplasia - genetics | Founder Effect | gamma Catenin | Desmoplakins - genetics | Desmocollins - genetics | Desmoglein 2 - genetics | Genetic Predisposition to Disease - genetics | Plakophilins - genetics | Genotype | Penetrance | Arrhythmogenic Right Ventricular Dysplasia - economics | Arrhythmogenic Right Ventricular Dysplasia - therapy | Chromosome Mapping - economics | Phenotype | Ryanodine Receptor Calcium Release Channel - genetics | Cost-Benefit Analysis | Alleles | Genetic Testing - economics | Sequence Analysis, DNA - economics | Dysplasia | Care and treatment | Patients' rights | Cardiomyopathy | Analysis | Genetic research | Heart diseases | Electrocardiography | Cardiac arrhythmia | Mutation | Genes
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4. Full Text Left-dominant arrhythmogenic cardiomyopathy in a large family: Associated desmosomal or nondesmosomal genotype?
by Groeneweg, Judith A., MD and van der Zwaag, Paul A., MD, PhD and Jongbloed, Jan D.H., PhD and Cox, Moniek G.P.J., MD, PhD and Vreeker, Arnold, BSc and de Boer, Rudolf A., MD, PhD and van der Heijden, Jeroen F., MD, PhD and van Veen, Toon A.B., PhD and McKenna, William J., MD, DSc and van Tintelen, J. Peter, MD,PhD and Dooijes, Dennis, PhD and Hauer, Richard N.W., MD, PhD
Heart Rhythm, ISSN 1547-5271, 2013, Volume 10, Issue 4, pp. 548 - 559
Background Arrhythmogenic cardiomyopathy (AC) is considered a predominantly right ventricular (RV) desmosomal disease. However, left-dominant forms due to... 
Cardiovascular | ARVC | Ventricular arrhythmias | Immunohistochemistry | Cardiomyopathy | Electrocardiogram | Programmed electrical stimulation | Genetics | Desmosome Gap junction | ACTIVATION | Desmosome | DILATED CARDIOMYOPATHY | Gap junction | PLAKOGLOBIN CAUSES | GENE | PLAKOPHILIN-2 MUTATIONS | EXPRESSION | SLOW CONDUCTION | RIGHT-VENTRICULAR CARDIOMYOPATHY | WAVE-FRONT CURVATURE | DYSPLASIA/CARDIOMYOPATHY | CARDIAC & CARDIOVASCULAR SYSTEMS | Cardiomyopathy, Dilated - genetics | Genetic Predisposition to Disease | Prognosis | Age Factors | Risk Assessment | Plakophilins - genetics | Humans | Middle Aged | Genotype | Male | Arrhythmogenic Right Ventricular Dysplasia - diagnosis | Genetic Testing - methods | Arrhythmogenic Right Ventricular Dysplasia - genetics | Desmosomes - genetics | Pedigree | Sex Factors | Tachycardia, Ventricular - genetics | Adult | Cardiomyopathy, Dilated - diagnosis | Female | Heterozygote | Aged | Mutation | Electrocardiography - methods | Sects | Tachycardia | Task forces | Gene mutations | Implants, Artificial | Prosthesis | Medical genetics | Electrocardiography | Genetic aspects | Heart diseases
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5. Full Text Standing on the Shoulders of Giants: J.A.P. Paré and the Birth of Cardiovascular Genetics
by Sen-Chowdhry, Srijita, MBBS, MD (Cantab), FESC and McKenna, William J., MD, DSc, FRCP
Canadian Journal of Cardiology, ISSN 0828-282X, 2015, Volume 31, Issue 11, pp. 1305 - 1308
Abstract Sudden death and stroke afflicted a family from rural Quebec with such frequency as to be called the Coaticook curse by the local community. In... 
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | FAMILIAL HYPERTROPHIC CARDIOMYOPATHY | MANAGEMENT | History, 21st Century | History, 20th Century | Humans | Quebec | Genetics, Medical - history | Cardiovascular Diseases - history | Cardiovascular Diseases - genetics
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6. Genetics of Restrictive Cardiomyopathy
by Sen-Chowdhry, Srijita and Syrris, Petros and McKenna, William J
Heart Failure Clinics, ISSN 1551-7136, 04/2010, Volume 6, Issue 2, pp. 179 - 186
Restrictive physiology, a severe form of diastolic dysfunction, is characteristically observed in the setting of constrictive pericarditis and myocardial... 
Restrictive cardiomyopathy | Diastolic dysfunction | Constrictive pericarditis | Sarcomeric disease | Myocardial restriction | Cardiomyopathy, Hypertrophic - genetics | Genetic Predisposition to Disease | Diastole | Cardiomyopathy, Restrictive - genetics | Humans | Risk Factors | Pericarditis, Constrictive - genetics | Sarcomeres - pathology
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7. Full Text Splicing and Dilated Cardiomyopathy
by MacRae, Calum A., MD, PhD and McKenna, William J., MD, DSc
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2009, Volume 54, Issue 10, pp. 942 - 943
Cardiovascular | Internal Medicine
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8. Full Text Reply
by Sen-Chowdhry, Srijita, MBBS, MD and Syrris, Petros, PhD and Prasad, Sanjay K., MD and Hughes, Siân E., MBBS, PhD and Merrifield, Robert, PhD and Ward, Deirdre, MBBS and Pennell, Dudley J., MD and McKenna, William J., MD, DSc
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2009, Volume 53, Issue 17, pp. 1571 - 1572
Cardiovascular | Internal Medicine
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9. Full Text Left ventricular strain and untwist in hypertrophic cardiomyopathy: Relation to exercise capacity
by Abozguia, Khalid, MBBCh, MRCP and Nallur-Shivu, Ganesh, MRCP and Phan, Thanh T., MRCP, PhD and Ahmed, Ibrar, MRCP and Kalra, Rajat and Weaver, Rebekah A., MSc and McKenna, William J., BA, MD, DSc, FRCP and Sanderson, John E., MA, MD, FRCP, FACC, FHKAM and Elliott, Perry, MD, FRCP, FACC, FESC and Frenneaux, Michael P., MD, FRCP, FACC, FMedSci
American Heart Journal, ISSN 0002-8703, 2010, Volume 159, Issue 5, pp. 825 - 832
Background Nonobstructive hypertrophic cardiomyopathy (nHCM) is often associated with reduced exercise capacity despite hyperdynamic systolic function as... 
Cardiovascular | MECHANICS | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | ABNORMALITIES | SPECKLE TRACKING ECHOCARDIOGRAPHY | HEART-FAILURE | CARDIOVASCULAR-DISEASE | TORSION | RELAXATION | SYSTOLIC FUNCTION | DIASTOLIC DYSFUNCTION | Humans | Middle Aged | Male | Torsion Abnormality - physiopathology | Oxygen Consumption - physiology | Rotation | Cardiomyopathy, Hypertrophic - physiopathology | Exercise Tolerance - physiology | Electrocardiography | Heart Rate - physiology | Echocardiography, Doppler - methods | Female | Aged | Cardiomyopathy, Hypertrophic - diagnostic imaging | Exercise | Cardiomyopathy, Hypertrophic | Ultrasonic imaging | Cardiology | Cardiomyopathy | Exports | Aerobic power | Clinical Investigation
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10. Full Text Clinical Impact of Genetics in Arrhythmogenic Cardiomyopathy
by Sen-Chowdhry, Srijita, MBBS, MD and Syrris, Petros, PhD and Quarta, Giovanni, MD and McKenna, William J., MD, DSc
Cardiac Electrophysiology Clinics, ISSN 1877-9182, 2011, Volume 3, Issue 2, pp. 205 - 215
In the past decade, elucidation of the genetic etiology of arrhythmogenic cardiomyopathy (AC) has shed light on the cellular and molecular mechanisms... 
Cardiovascular | Genetics | Diagnosis | Sudden death | Arrhythmogenic right ventricular cardiomyopathy/dysplasia | Gene testing
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11. Full Text Genetics of Dilated Cardiomyopathy: Risk of Conduction Defects and Sudden Cardiac Death
by Arnous, Samer, MBBS, MRCPI and Syrris, Petros, PhD and Sen-Chowdhry, Srijita, MRCP, MD, FESC and McKenna, William J., MD, DSc, FRCP, FESC
Cardiac Electrophysiology Clinics, ISSN 1877-9182, 2010, Volume 2, Issue 4, pp. 599 - 609
Dilated cardiomyopathy is familial in at least 40--60% of cases and causal mutations have been identified in more than 40 different genes. Mutations in lamin... 
Cardiovascular | Conduction defect | Familial dilated cardiomyopathy | Arrhythmia | Sudden cardiac death | Laminopathy | Left ventricular arrhythmogenic cardiomyopathy
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12. Full Text Reply
by Lambiase, Pier D., MD, PhD and Nunn, Laurence M., MD and Bhar-Amato, Justine, MD and Lowe, Martin D., MD, PhD and Macfarlane, Peter W., MD, DSc and Rogers, Pauline, MSc and McKenna, William J., MD and Elliott, Perry M., MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2012, Volume 59, Issue 18, pp. 1660 - 1661
Cardiovascular | Internal Medicine
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13. Full Text Prevalence of J-Point Elevation in Sudden Arrhythmic Death Syndrome Families
by Nunn, Laurence M., MD and Bhar-Amato, Justine, MD and Lowe, Martin D., MD, PhD and Macfarlane, Peter W., MD, DSc and Rogers, Pauline, MSc and McKenna, William J., MD and Elliott, Perry M., MD and Lambiase, Pier D., MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 58, Issue 3, pp. 286 - 290
Objectives The purpose of this study was to assess the prevalence of J-point elevation among the relatives of sudden arrhythmic death syndrome (SADS) probands.... 
Cardiovascular | Internal Medicine | J-point elevation | sudden arrhythmic death | early repolarization | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC-ARREST | CHANNEL | VENTRICULAR-FIBRILLATION | UNEXPLAINED DEATH | NATIONAL-SURVEY | DIAGNOSTIC YIELD | VARIANT | J-WAVE SYNDROMES | Ventricular Fibrillation - diagnosis | Humans | Electrocardiography | Ventricular Fibrillation - genetics | Adult | Female | Male | Arrhythmias, Cardiac - diagnosis | Death, Sudden, Cardiac - etiology | Arrhythmias, Cardiac - genetics | Universities and colleges | Electrocardiogram | Prevalence studies (Epidemiology) | Research institutes | Confidence intervals | Cardiac arrhythmia | Heart attacks | Mortality | Population | Drug therapy | Females | Age
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14. Full Text Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study
by Thomas, Kim S., PhD and Ormerod, Anthony D., MD and Craig, Fiona E., MBBS and Greenlaw, Nicola, MSc and Norrie, John, MSc and Mitchell, Eleanor, BA and Mason, James M., DPhil and Johnston, Graham A., FRCP and Wahie, Shyamal, MBBS and Williams, Hywel C., DSc and UK Dermatology Clinical Trials Net and UK Dermatology Clinical Trials Network's STOP GAP Team
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 75, Issue 5, pp. 940 - 949
Background Pyoderma gangrenosum (PG) is an uncommon dermatosis with a limited evidence base for treatment. Objective We sought to estimate the effectiveness of... 
Dermatology | corticosteroid | cohort | side effects | pyoderma gangrenosum | topical therapy | tacrolimus | UNITED-KINGDOM | DISEASE | DERMATOLOGY | Pyoderma Gangrenosum - drug therapy | Recurrence | Prospective Studies | Dermatologic Agents - administration & dosage | Humans | Middle Aged | Male | Treatment Outcome | Dermatologic Agents - therapeutic use | Skin Ulcer - etiology | Administration, Cutaneous | Tacrolimus - therapeutic use | Medication Adherence | Skin Ulcer - drug therapy | Pyoderma Gangrenosum - complications | Anti-Inflammatory Agents - therapeutic use | Quality of Life | Adult | Anti-Inflammatory Agents - administration & dosage | Clobetasol - administration & dosage | Female | Aged | Clobetasol - therapeutic use | Tacrolimus - administration & dosage | Medicine, Experimental | Medical research | Care and treatment | Pyoderma | Patient outcomes | Corticosteroids
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15. Full Text The effects of structural recovery and thermal lag in temperature-modulated DSC measurements
by Simon, Sindee L and McKenna, Gregory B
Thermochimica Acta, ISSN 0040-6031, 1997, Volume 307, Issue 1, pp. 1 - 10
It is well known that structural recovery in polymeric glass formers leads to the enthalpy overshoot in nonisothermal experiments. One common model for... 
Scanning calorimetry | Temperature-modulated DSC | Structural recovery | Calorimetry | Lissajous loops | Dynamic calorimetry | Tool-Narayanaswamy model | Tool-narayanaswamy model | CHEMISTRY, ANALYTICAL | calorimetry | structural recovery | AMORPHOUS POLYMERS | CHEMISTRY, PHYSICAL | RELAXATION | DIFFERENTIAL SCANNING CALORIMETRY | GLASS-TRANSITION | scanning calorimetry | CONDUCTIVITY | PARAMETER MODEL | dynamic calorimetry | temperature-modulated DSC | HEAT-CAPACITY
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16. Full Text Hypertrophic Cardiomyopathy
by Behr, Elijah R and McKenna, William J
Current Treatment Options in Cardiovascular Medicine, ISSN 1092-8464, 11/2002, Volume 4, Issue 6, pp. 443 - 453
When an individual is diagnosed with hypertrophic cardiomyopathy (HCM), all relatives potentially affected by Mendelian autosomal-dominant inheritance should... 
Medicine & Public Health | Cardiology | Anticoagulants (Medicine) | Cardiomyopathy, Hypertrophic
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17. Full Text Cardiovascular complications of neuromuscular disorders
by Sachdev, Bhavesh and Elliott, Perry M and McKenna, William J
Current Treatment Options in Cardiovascular Medicine, ISSN 1092-8464, 04/2002, Volume 4, Issue 2, pp. 171 - 179
In the past decade, advances in molecular genetics have shown that many familial neuromuscular and cardiovascular diseases share a common pathophysiology. They... 
Medicine & Public Health | Cardiology | Complications and side effects | Anticoagulants (Medicine)
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18. Full Text High strain rate mechanical properties of a cross-linked epoxy across the glass transition
by Sirk, Timothy W and Khare, Rajesh and Khare, Ketan S and Karim, Mir and Lenhart, Joseph L and Andzelm, Jan W and McKenna, Gregory B
Polymer, ISSN 0032-3861, 12/2013, Volume 54, Issue 26, pp. 7048 - 7057
Molecular dynamics simulations were used to study the high strain rate mechanical properties of a cross-linked epoxy system comprised of diglycidyl ether of... 
Molecular simulation | High strain rate mechanical properties | Cross-linked epoxy | POLYMER SCIENCE | THERMOMECHANICAL RESPONSE | AMORPHOUS POLYMERS | BEHAVIOR | EFFICIENT GENERATION | NETWORK STRUCTURE | DEFORMATION | DENSITY | VISCOELASTIC POISSONS RATIO | AM1-BCC MODEL | MOLECULAR-DYNAMICS SIMULATIONS | Mechanical properties | Bisphenol-A | Analysis | Epoxy resins
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19. Full Text Effects of confinement on material behaviour at the nanometre size scale
by Alcoutlabi, Mataz and McKenna, Gregory B
Journal of Physics: Condensed Matter, ISSN 0953-8984, 04/2005, Volume 17, Issue 15, pp. R461 - R524
In this article, the effects of size and confinement at the nanometre size scale on both the melting temperature, T-m, and the glass transition temperature,... 
PHYSICS, CONDENSED MATTER | GLASS-TRANSITION TEMPERATURE | LENNARD-JONES MIXTURE | SURFACE RELAXATION PROCESS | GROWING LENGTH SCALES | MODE-COUPLING THEORY | THIN POLYMER-FILMS | NEUTRON-SCATTERING EXPERIMENTS | MELTING-POINT DEPRESSION | MONTE-CARLO-SIMULATION | MOLECULAR-DYNAMICS SIMULATION
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