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Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P688 - P689
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P432 - P433
Journal Article
Neuropharmacology, ISSN 0028-3908, 02/2014, Volume 77, pp. 131 - 144
Journal Article
2012, 2012, Handbook of experimental pharmacology, ISBN 9783642257575, Volume 213, x, 455
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing... 
Schizophrenia | Antipsychotic Agents | Pharmacology | Treatment | drug therapy | Other branches of medicine | Biomedicine | Biological Psychology | Pharmacology/Toxicology | Pharmacy | Psychopharmacology
Book
American Journal of Psychiatry, ISSN 0002-953X, 08/2008, Volume 165, Issue 8, pp. 1033 - 1039
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 03/2010, Volume 35, Issue 4, pp. 855 - 869
We recently identified LY2033298 as a novel allosteric potentiator of acetylcholine (ACh) at the M(4) muscarinic acetylcholine receptor (mAChR). This study... 
Schizophrenia | Drug discovery | Allosteric modulation | Functional selectivity | Multivariate Analysis | Cricetulus | Receptor, Muscarinic M4 - physiology | Acetylcholine - metabolism | Protein Transport - drug effects | Corpus Striatum - metabolism | Dose-Response Relationship, Drug | Allosteric Site - physiology | Nicotinic Acids - chemistry | Tritium - metabolism | Allosteric Regulation - physiology | Radioligand Assay - methods | Muscarinic Antagonists - pharmacokinetics | Phosphorylation - drug effects | Allosteric Regulation - drug effects | Cell Line | Cricetinae | Acetylcholine - pharmacology | Allosteric Site - drug effects | Models, Molecular | Rats | Thiophenes - pharmacology | Nicotinic Acids - pharmacology | Avoidance Learning - physiology | Mice, Knockout | Parasympatholytics - pharmacokinetics | Binding, Competitive - drug effects | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Animals | Antipsychotic Agents - chemistry | Signal Transduction - drug effects | Receptor, Muscarinic M4 - drug effects | Corpus Striatum - drug effects | Receptor, Muscarinic M4 - chemistry | Signal Transduction - physiology | Avoidance Learning - drug effects | Mice | N-Methylscopolamine - pharmacokinetics | Quinuclidinyl Benzilate - pharmacokinetics | Antipsychotic Agents - pharmacology | In Vitro Techniques | Receptor, Muscarinic M4 - deficiency | Thiophenes - chemistry | Tritium - pharmacokinetics | Index Medicus | Receptor Pharmacology | drug discovery | molecular pharmacology | Development | GPCR | Acetylcholine | schizophrenia | Neuropharmacology | Original | functional selectivity | drug receptor interaction | allosteric modulation
Journal Article
Journal Article
The International Journal of Neuropsychopharmacology, ISSN 1461-1457, 9/2010, Volume 13, Issue 8, pp. 1021 - 1033
Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 01/2009, Volume 166, Issue 1, pp. 113 - 113
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 04/2007, Volume 321, Issue 1, pp. 308 - 317
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 03/2010, Volume 35, Issue 4, pp. 855 - 869
We recently identified LY2033298 as a novel allosteric potentiator of acetylcholine (ACh) at the M sub(4) muscarinic acetylcholine receptor (mAChR). This study... 
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 7/2007, Volume 193, Issue 1, pp. 121 - 136
Data from both preclinical and clinical studies have provided proof of concept that modulation of limbic and forebrain glutamate, via mGlu2/3 receptor... 
Animal models | Biomedicine | mGlu2/3 receptor agonist | Schizophrenia | Antipsychotic | Anxiety | Pharmacology/Toxicology | Psychiatry | Psychiatric disorders | Anxiolytic | Metabotropic glutamate (mGlu) receptors | MGlu2/3 receptor agonist | SINGLY HOUSED MICE | animal models | METABOTROPIC GLUTAMATE-RECEPTOR | RAT | PSYCHIATRY | ACID LY354740 | schizophrenia | metabotropic glutamate (mGlu) receptors | NEUROSCIENCES | NUCLEUS-ACCUMBENS | PHENCYCLIDINE | anxiety | MESSENGER-RNA | MEDIAL PREFRONTAL CORTEX | PHARMACOLOGY & PHARMACY | antipsychotic | anxiolytic | psychiatric disorders | STRESS-INDUCED HYPERTHERMIA | Cyclic S-Oxides - chemistry | Phencyclidine - pharmacology | Rats, Inbred F344 | Motor Activity - drug effects | Male | Amino Acids - pharmacology | Diazepam - pharmacology | Dose-Response Relationship, Drug | Prefrontal Cortex - drug effects | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Behavior, Animal - drug effects | Cyclic S-Oxides - pharmacology | Molecular Structure | Xanthenes - pharmacology | Disease Models, Animal | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Amphetamine - pharmacology | Rats | Rats, Sprague-Dawley | Mental Disorders - psychology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Cyclic S-Oxides - therapeutic use | Animals | Mental Disorders - drug therapy | Prefrontal Cortex - metabolism | Mice | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Neurology | Brain | Pharmacology | Psychology | Rodents | Index Medicus
Journal Article