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PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 3, pp. e0209947 - e0209947
Cannabis withdrawal upon discontinuation of long-term, heavy Cannabis use is reported in humans; however, methods to establish the nature and intensity of... 
Journal Article
Drug and Alcohol Dependence, ISSN 0376-8716, 2016, Volume 165, pp. 87 - 93
Highlights • Cannabidiol lacks CB1 receptor agonist or antagonist activity in primates. • Cannabidiol amounts larger than those in Cannabis or nabiximols... 
Psychiatry | Rhesus monkey | Drug discrimination | Serotonin | Rimonabant | Dependence | 5-HT1A | Cannabidiol | Cannabinoid | 8-OH-DPAT | rhesus monkey | cannabidiol | serotonin | rimonabant | drug discrimination | cannabinoid | dependence
Journal Article
Drug and Alcohol Dependence, ISSN 0376-8716, 08/2016, Volume 165, p. 87
* Cannabidiol lacks CB.sub.1 receptor agonist or antagonist activity in primates. * Cannabidiol amounts larger than those in Cannabis or nabiximols enhance... 
Cannabinoids | Marijuana
Journal Article
PSYCHOPHARMACOLOGY, ISSN 0033-3158, 03/2017, Volume 234, Issue 5, pp. 781 - 792
The extent to which non-alpha 4 beta 2 versus alpha 4 beta 2* nAChRs contribute to the behavioral effects of varenicline and other nAChR agonists is unclear.... 
Drug discrimination | SMOKING-CESSATION | CYTISINE | EFFICACY | PSYCHIATRY | Varenicline | RATS | ANTAGONISM | SUBUNITS | METHYLLYCACONITINE | NEUROSCIENCES | Mecamylamine | PARTIAL AGONIST | DH beta E | ETHANOL | PHARMACOLOGY & PHARMACY | beta 2 nAChRs | Nicotine
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 09/2019, Volume 370, Issue 3, pp. 380 - 389
Better therapeutic options are needed for pain. Baclofen, buspirone, and morphine are characterized as having analgesic properties. However, little is known... 
Index Medicus
Journal Article
Drug and Alcohol Dependence, ISSN 0376-8716, 2015, Volume 151, pp. 284 - 288
Journal Article
Psychopharmacology, ISSN 0033-3158, 03/2017, Volume 234, Issue 5, p. 781
The extent to which non-[alpha]4[beta]2 versus [alpha]4[beta]2* nAChRs contribute to the behavioral effects of varenicline and other nAChR agonists is unclear.... 
Pharmacology, Experimental | Psychopharmacology | Physiological aspects | Research | Nicotinic receptors | Drug therapy | Health aspects | Nicotine | Tobacco habit | Prescription drugs | Smoking cessation | Drug dosages
Journal Article
Behavioural Pharmacology, ISSN 0955-8810, 08/2019, Volume 30, Issue 5, pp. 412 - 421
Varenicline is a smoking cessation pharmacotherapy with a presumed mechanism of action of partial efficacy at the α4β2 nicotinic acetylcholine receptor... 
nicotine | DESENSITIZATION | epibatidine | ANTAGONISM | NEUROSCIENCES | cytisine | operant responding | varenicline | cross-tolerance | hypothermia | PARTIAL AGONIST | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | DISCRIMINATIVE STIMULUS | tolerance | ALPHA-4-BETA-2 | Physiological aspects | Models | Nicotinic receptors | Drug tolerance | Health aspects
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2012, Volume 340, Issue 1, pp. 37 - 45
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 04/2019, Volume 179, pp. 27 - 33
Mecamylamine is a non-competitive nicotinic acetylcholine receptor (nAChR) antagonist that has been prescribed for hypertension and as an off-label smoking... 
CUE | ANTAGONIST | RATS | LOCOMOTOR-ACTIVITY | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | BLOCKADE | AGONISTS | NEUROSCIENCES | Hypertension | Smoking cessation programs | Methyl aspartate | Antidepressants | Analysis
Journal Article
Drug Development and Industrial Pharmacy, ISSN 0363-9045, 05/2019, Volume 45, Issue 5, pp. 861 - 867
Acetylcholinesterase (AChE) inhibitors and positive allosteric nicotinic acetylcholine receptor (nAChR) modulators are potential pharmacotherapies for nicotine... 
donepezil | drug development | smoking cessation | galantamine | Nicotine | POSITIVE ALLOSTERIC MODULATOR | CHEMISTRY, MEDICINAL | PHARMACOLOGICAL CHARACTERIZATION | SMOKING | PHYSOSTIGMINE | IN-VITRO | DRUGS | PHARMACOLOGY & PHARMACY
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2011, Volume 162, Issue 5, pp. 1060 - 1073
BACKGROUND AND PURPOSE The extent to which behavioural effects vary as a function of CB1 receptor agonist efficacy is not clear. These studies tested the... 
rhesus monkey | cross-tolerance | drug discrimination | cannabinoid | efficacy | fixed ratio responding | tolerance | RECEPTOR | SIGNAL-TRANSDUCTION | DISCRIMINATIVE-STIMULUS | MORPHINE-TOLERANCE | APPARENT PA ANALYSIS | NONTOLERANT PIGEONS | DELTA-TETRAHYDROCANNABINOL | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | AGONIST
Journal Article
Expert review of clinical pharmacology, 01/2019
Green tobacco sickness occurs from transdermal absorption of chemicals from freshly harvested, green tobacco leaves. Signs and symptoms include nausea,... 
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 05/2015, Volume 353, Issue 2, pp. 261 - 268
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2017, Volume 116, p. 9
Quantitative analysis of antagonism is infrequently used to identify nAChRs mediating behavioral effects. Here, nicotine (0.032 mg/kg i.v.) was established as... 
Analysis | Smoking | Morphine | Cocaine
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2016, Volume 173, Issue 24, pp. 3454 - 3466
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2017, Volume 116, pp. 9 - 17
Quantitative analysis of antagonism is infrequently used to identify nAChRs mediating behavioral effects. Here, nicotine (0.032 mg/kg i.v.) was established as... 
Journal Article
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