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Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 272 - 276
Journal Article
Health Education, ISSN 0965-4283, 01/2019, Volume 119, Issue 1, pp. 63 - 82
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2016, Volume 34, Issue 4_suppl, pp. 554 - 554
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 12/2017, Volume 60, Issue 24, pp. 10071 - 10091
Herein we report the optimization of a series of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) using X-ray crystal... 
L265P SOMATIC MUTATION | POTENT | CHEMISTRY, MEDICINAL | SERIES | PYOGENIC BACTERIAL-INFECTIONS | IBRUTINIB | HUMANS | PART 1 | PREVALENCE | IDENTIFICATION | MYD88
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2017, Volume 60, Issue 24, pp. 10071 - 10091
Herein we report the optimization of a series of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) using X-ray crystal... 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2147 - 2147
First generation mTOR inhibitors (rapalogs) have modest activity in some tumors. We sought to delineate the likely resistance mechanisms to existing mTOR... 
Journal Article
Nature chemical biology, ISSN 1552-4450, 10/2016, Volume 12, Issue 10, pp. 815 - 821
The structure-specific nuclease human flap endonuclease-1 (hFEN1) plays a key role in DNA replication and repair and may be of interest as an oncology target.... 
Journal Article
JNCCN Journal of the National Comprehensive Cancer Network, ISSN 1540-1405, 12/2016, Volume 14, Issue 12, pp. 1536 - 1543
Background: BRAF-mutant metastatic colorectal cancers (mCRCs) share many clinicopathologic features with right-sided colon tumors, including frequent... 
FALSE DISCOVERY RATE | COLON-CANCER | MOLECULAR-FEATURES | 1ST-LINE TREATMENT | ONCOLOGY | MICROSATELLITE INSTABILITY | MUTATION | GENE-EXPRESSION | PHASE-II | OPEN-LABEL | FOLFIRI PLUS BEVACIZUMAB
Journal Article
MedChemComm, ISSN 2040-2503, 10/2014, Volume 5, Issue 10, pp. 1533 - 1539
A novel series of PAK1 inhibitors was discovered from a kinase directed screen. SAR exploration in the selectivity pocket and solvent tail regions was... 
CHEMISTRY, MEDICINAL | I P21-ACTIVATED KINASES | CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGRESSION | DISCOVERY
Journal Article
by Ager, Casey and Reilley, Matthew and Nicholas, Courtney and Bartkowiak, Todd and Jaiswal, Ashvin and Curran, Michael and Albershardt, Tina C and Bajaj, Anshika and Archer, Jacob F and Reeves, Rebecca S and Ngo, Lisa Y and Berglund, Peter and ter Meulen, Jan and Denis, Caroline and Ghadially, Hormas and Arnoux, Thomas and Chanuc, Fabien and Fuseri, Nicolas and Wilkinson, Robert W and Wagtmann, Nicolai and Morel, Yannis and Andre, Pascale and Atkins, Michael B and Carlino, Matteo S and Ribas, Antoni and Thompson, John A and Choueiri, Toni K and Hodi, F. Stephen and Hwu, Wen-Jen and McDermott, David F and Atkinson, Victoria and Cebon, Jonathan S and Fitzharris, Bernie and Jameson, Michael B and McNeil, Catriona and Hill, Andrew G and Mangin, Eric and Ahamadi, Malidi and van Vugt, Marianne and van Zutphen, Mariëlle and Ibrahim, Nageatte and Long, Georgina V and Gartrell, Robyn and Blake, Zoe and Simoes, Ines and Fu, Yichun and Saito, Takuro and Qian, Yingzhi and Lu, Yan and Saenger, Yvonne M and Budhu, Sadna and De Henau, Olivier and Zappasodi, Roberta and Schlunegger, Kyle and Freimark, Bruce and Hutchins, Jeff and Barker, Christopher A and Wolchok, Jedd D and Merghoub, Taha and Burova, Elena and Allbritton, Omaira and Hong, Peter and Dai, Jie and Pei, Jerry and Liu, Matt and Kantrowitz, Joel and Lai, Venus and Poueymirou, William and MacDonald, Douglas and Ioffe, Ella and Mohrs, Markus and Olson, William and Thurston, Gavin and Capasso, Cristian and Frascaro, Federica and Carpi, Sara and Tähtinen, Siri and Feola, Sara and Fusciello, Manlio and Peltonen, Karita and Martins, Beatriz and Sjöberg, Madeleine and Pesonen, Sari and Ranki, Tuuli and Kyruk, Lukasz and Ylösmäki, Erkko and Cerullo, Vincenzo and Cerignoli, Fabio and Xi, Biao and Guenther, Garret and Yu, Naichen and Muir, Lincoln and Zhao, Leyna and Abassi, Yama and Cervera-Carrascón, Víctor and Siurala, Mikko and Santos, João and Havunen, Riikka and Parviainen, Suvi and Hemminki, Akseli and ...
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 11/2016, Volume 4, Issue S1
Journal Article
Drones, ISSN 2504-446X, 04/2019, Volume 3, Issue 2, p. 34
Accurate and precise population estimates form the basis of conservation action but are lacking for many arboreal species due to the high costs and difficulty... 
conservation | primates | population monitoring | unmanned aerial vehicles | Ateles
Journal Article
Mail on Sunday, 01/2014
  Yesterday, near the boy's Edinburgh home, well-wishers and members of the public who had given their time to search for Mikaeel paid emotional tribute to him... 
Boys | Children & youth
Newspaper Article
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