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BLOOD, ISSN 0006-4971, 03/2019, Volume 133, Issue 13, pp. 1427 - 1435
The classical model of hematopoiesis proposes a hierarchy in which a small number of multipotent hematopoietic stem cells (HSCs) maintain all blood lineages by... 
MYELOID PROGENITOR | STIMULATION | HEMATOPOIETIC STEM-CELLS | TRANSCRIPTION | BIOLOGY | SELF-RENEWAL | PLATELET PRODUCTION | C-MPL LIGAND | IDENTIFICATION | HEMATOLOGY | EXPRESSION
Journal Article
Advances in Biological Regulation, ISSN 2212-4926, 01/2019, Volume 71, pp. 55 - 68
Myeloproliferative neoplasms (MPNs) are haematopoietic stem cell-derived clonal disorders characterised by proliferation of some or all myeloid lineages,... 
Heterogeneity | JAK-STAT signaling | Haematopoietic stem cell | Myeloproliferative neoplasms | Phenotypes | Myelofibrosis | Complications | Leukemia | Disorders | Health risks | Viruses | Disease control | Patients | Neoplasms | Subgroups | Calreticulin | Janus kinase 2 | Stem cells | Bone marrow | Janus kinase | Mutation | Tumors
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1784 - 1784
Abstract MAJIC-ET is a phase 2 study comparing ruxolitinib (RUX) to best available therapy (BAT) in hydroxycarbamide resistant/intolerant (HC-RES/INT)... 
Journal Article
Blood, ISSN 0006-4971, 10/2019
Key Points Splicing factor and TP53 mutations identify ET patients at very high risk of disease progression Ruxolitinib treatment does not reduce... 
Journal Article
Haematologica, ISSN 0390-6078, 04/2019, p. haematol.2018.205351
Somatic mutations in acute myeloid leukemia are acquired sequentially and hierarchically. First, pre-leukemic mutations, such as t(8;21) that encodes AML1-ETO,... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4281 - 4281
Abstract Background : MF is a hematologic malignancy characterized by splenomegaly and debilitating systemic symptoms. The Myeloproliferative Neoplasm Symptom... 
Journal Article
Lancet Infectious Diseases, The, ISSN 1473-3099, 2016, Volume 16, Issue 5, pp. 556 - 564
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2017, Volume 23, Issue 6, pp. 692 - 702
Journal Article
Boston Bar Journal, ISSN 0524-1111, 03/2016, Volume 60, Issue 2
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 10/2015, Volume 24, Issue 1, pp. R74 - R84
Journal Article