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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. E2326 - E2334
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2018, Volume 14, Issue 2, p. e1005965
A key constraint in genomic testing in oncology is that matched normal specimens are not commonly obtained in clinical practice. Thus, while well-characterized... 
BREAST-CANCER | PRIMARY TUMOR | METASTASES | GENES | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MUTATIONS | CONCORDANCE | DISCOVERY | Colonic Neoplasms - genetics | Exons | Genomics | Humans | Databases, Genetic | DNA Copy Number Variations | Exome | Neoplasms - genetics | Computer Simulation | Germ-Line Mutation | Female | Lung Neoplasms - genetics | Reproducibility of Results | Carcinoma, Non-Small-Cell Lung - genetics | Gene Frequency | Computational Biology | Probability | Homozygote | Algorithms | Breast Neoplasms - genetics | Ploidies | Alleles | Heterozygote | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | Mutation | Genome, Human | Sequence Analysis, DNA - methods | Medical research | Colon cancer | Analysis | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Chromosomes | Genetic screening | Cancer | Oncology, Experimental | Nucleotide sequencing | Research | Diagnosis | Methods | DNA sequencing | Copy number | Lung cancer | Oncology | Employees | Genomes | Statistical methods | Single-nucleotide polymorphism | Metastasis | Gene sequencing | Alterations | Audio frequencies | Mathematical models | Colon | Bioinformatics | Supervision | Deoxyribonucleic acid--DNA | Predictive control | Ploidy | Statistical analysis | Patients | Medicine | Zygosity | Gene frequency | Computation | Cell lines | Computer applications | Predictions | Software | Genetic testing | Tumors | Life Sciences | Biochemistry, Molecular Biology | Deoxyribonucleic acid | DNA
Journal Article
Journal of Virology, ISSN 0022-538X, 01/2018, Volume 92, Issue 1
Increasing evidence suggests that repetitive elements may play a role in host gene regulation, particularly through the donation of alternative promoters,... 
Mammary cell transformation | Provirus expression | Human endogenous retrovirus | provirus expression | LINE TERA-1 | HUMAN-BREAST-CANCER | SEQUENCES | human endogenous retrovirus | PROVIRUSES | ENDOGENOUS RETROVIRUS GENOME | VIROLOGY | GENE | ALIGNMENT | mammary cell transformation | GENERATION | EXPRESSION | T-CELLS | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2018, Volume 13, Issue 11, p. e0208097
Journal Article
The Oncologist, ISSN 1083-7159, 09/2018, Volume 23, Issue 9, pp. 998 - 1003
Biliary tract cancers such as cholangiocarcinoma represent a heterogeneous group of cancers that can be difficult to diagnose. Recent comprehensive genomic... 
CELL LUNG-CANCER | TARGETED THERAPY | SURVIVAL | GENE FUSIONS | INTRAPULMONARY METASTASIS | MELANOMA | EVOLUTION | ONCOLOGY | RECURRENT | MUTATION | LOW-GRADE ASTROCYTOMAS | Molecular Tumor Board | Precision Medicine Clinic
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 10/2019, Volume 25, Issue 19, pp. 5961 - 5971
Purpose: Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous malignancy, which has demonstrated sensitivity to immune checkpoint inhibitor therapy.... 
SURVIVAL | PROFILES | POLYOMAVIRUS | PEMBROLIZUMAB | ONCOLOGY | RECURRENT | PD-1 BLOCKADE | MUTATIONAL LANDSCAPE | CHEMOTHERAPY
Journal Article
01/2017, ISBN 9780355099751
Increasing evidence suggests that repetitive elements may play a role in host gene regulation, particularly through the donation of alternative promoters,... 
Microbiology | Genetics | Virology
Dissertation
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2016, Volume 113, Issue 16, p. E2326
  Endogenous retroviruses (ERVs) have contributed to more than 8% of the human genome. The majority of these elements lack function due to accumulated... 
Viruses | Genomes | Mutation | Polymorphism
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 04/2016, Volume 113, Issue 16, pp. E2326 - E2326
Endogenous retroviruses (ERVs) have contributed to more than 8% of the human genome. The majority of these elements lack function due to accumulated mutations... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 2773 - 2773
Abstract Introduction: The BeatAML master trial is evaluating the use of precision medicine via genomically guided therapy in acute myeloid leukemia (AML). A... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. 9523 - 9523
Journal Article
JCI INSIGHT, ISSN 2379-3708, 03/2019, Volume 4, Issue 6
BACKGROUND. PD-L1 expression and tumor mutational burden (TMB) have emerged as important biomarkers of response to immune checkpoint inhibitor (ICI) therapy.... 
MEDICINE, RESEARCH & EXPERIMENTAL | CTLA-4 BLOCKADE | PEMBROLIZUMAB | LANDSCAPE | CARCINOMA
Journal Article
Cancer Immunology Research, ISSN 2326-6066, 06/2019, Volume 7, Issue 6, pp. 866 - 873
Advanced and metastatic squamous cell carcinomas (SCC) are common and difficult-to-treat malignancies. We assessed 75 immunotherapy-treated patients with SCC... 
Journal Article
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