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Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 50, Issue 5, pp. 673 - 678
Journal Article
Current Drug Targets, ISSN 1389-4501, 11/2011, Volume 12, Issue 12, pp. 1772 - 1781
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0177332
...Author(s): Be'eri Niego 1,*, Natasha Lee 1, Pia Larsson 2, T. Michael De Silva 3, Amanda E-Ling Au 1, Fiona McCutcheon 1, Robert L. Medcalf 1 Introduction... 
Astrocytes - drug effects | Cell Line | Gene Expression | Signal Transduction | Tissue Plasminogen Activator - metabolism | Endothelial Cells - metabolism | Humans | rho-Associated Kinases - genetics | Permeability | Heterocyclic Compounds, 4 or More Rings - pharmacology | rho-Associated Kinases - antagonists & inhibitors | Blood-Brain Barrier - metabolism | Brain - metabolism | Animals | Tissue Plasminogen Activator - pharmacology | rho-Associated Kinases - metabolism | Protein Isoforms | Mice | Fibrinolysin - metabolism | Astrocytes - metabolism | Care and treatment | Patient outcomes | Dosage and administration | Thrombolytic drugs | Cerebral edema | Health aspects | Intracerebral hemorrhage | Risk factors | Endothelium | Multiplication | Coagulation | Smooth muscle | Glucose | Neuronal-glial interactions | Noma | Signal transduction | Blood-brain barrier | Ischemia | Hemoglobin | Acetylation | Inhibition | Thromboembolism | Astrocytes | Fetuses | Anatomy | Metabolism | Gene expression | Diseases | Pathology | Inhibitors | Isoforms | Atorvastatin | Affinity | Infiltration | Protein-serine/threonine kinase | Clinical medicine | Blood diseases | Monocyte chemoattractant protein 1 | Biotechnology | Blood coagulation | Animal models | Microbiology | Amino acids | Homology | Viruses | Activation | Kinases | Hemorrhage | Rodents | Bradykinin | Cardiology | Immune system | Hypertension | Edema | Stroke | Neurons | Light emitting diodes | Pharmacology | Ribonucleic acid--RNA | Blood flow | Flow | Medicine | Brain research | Protein kinase | Cell lines | Cancer | RNA | Ribonucleic acid
Journal Article
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 10/2019, Volume 29, Issue 5, pp. 1178 - 1191.e6
Traumatic brain injury (TBI) leaves many survivors with long-term disabilities. A prolonged immune response in the brain may cause neurodegeneration, resulting... 
CD8+ T cells | granzyme B | adaptive immune cells | neuroimmunology | traumatic brain injury | B cells | autoantibodies | SYSTEM | MYELIN CLEARANCE | LIMIT CNS INFLAMMATION | MULTIPLE-SCLEROSIS | MOTOR | SPINAL-CORD-INJURY | EXPERIMENTAL STROKE | DEFICIENT MICE | GAIT IMPAIRMENT | LYMPHOCYTES | CELL BIOLOGY
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 03/2019, Volume 10, p. 591
...Author(s): Dominik F. Draxler, Felix Lee, Heidi Ho, Charithani B. Keragala, Robert L. Medcalf, Be'eri Niego Introduction: Acute ischemic stroke (AIS... 
MCAo | TISSUE-PLASMINOGEN ACTIVATOR | TPA | immunosuppression | IMMUNOLOGY | stroke | BLOOD-BRAIN-BARRIER | PATHOPHYSIOLOGY | plasminogen | immune system | THROMBOLYSIS | MODULATION | t-PA | Stroke (Disease) | Nervous system diseases | Care and treatment | Immune response | Analysis
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2008, Volume 107, Issue 4, pp. 1091 - 1101
Glutamate is the main excitatory neurotransmitter of the CNS. Tissue‐type plasminogen activator (tPA) is recognized as a modulator of glutamatergic... 
serine protease inhibitor | NMDA receptor | low‐density lipoprotein receptor family | tissue‐type plasminogen activator | plasmin | Low-density lipoprotein receptor family | Serine protease inhibitor | Tissue-type plasminogen activator | Plasmin | low-density lipoprotein receptor family | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXCITOTOXIC INJURY | BLOOD-BRAIN-BARRIER | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | SUBSTRATE-SPECIFICITY | PROTEOLYTIC ACTIVITY | IN-VIVO | INHIBITOR COMPLEXES | LONG-TERM POTENTIATION | tissue-type plasminogen activator | METHYL-D-ASPARTATE | CALCIUM RESPONSES | Age Factors | Calcium - metabolism | Membrane Potentials - radiation effects | Cerebral Cortex - cytology | Oocytes | N-Methylaspartate - pharmacology | Drug Interactions | Thrombin - pharmacology | Amyloid beta-Protein Precursor - metabolism | Neurons - drug effects | Animals, Newborn | Membrane Potentials - drug effects | Receptors, N-Methyl-D-Aspartate - drug effects | Glutamic Acid - pharmacology | Mice, Inbred C57BL | Xenopus laevis | Cells, Cultured | Rats | Receptors, Cell Surface - metabolism | Membrane Potentials - physiology | Receptors, N-Methyl-D-Aspartate - physiology | rap GTP-Binding Proteins - pharmacology | Patch-Clamp Techniques | Animals | Tissue Plasminogen Activator - pharmacology | Glycine - pharmacology | Protease Nexins | Mice | Fibrinolysin - pharmacology | Methyl aspartate | Thrombin | Protease inhibitors | Tissue plasminogen activator | Low density lipoproteins | Domestic relations | Neurology | Signal transduction | Neurotransmitters | Biochemistry | Substrates | Index Medicus
Journal Article