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1. Full Text Non-zero-sum game of transfusions: EOL in leukemia
by Medeiros, Bruno C
Blood, ISSN 0006-4971, 08/2018, Volume 132, Issue 7, pp. 676 - 678
Inability to provide transfusion support to patients with leukemia is a major cause of delays in hospice enrollment for end-of-life (EOL) care. In this issue... 
HEMATOLOGY | ACUTE MYELOID-LEUKEMIA | OUTCOMES | Index Medicus | Abridged Index Medicus
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2. Full Text Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin
by Narayan, Rupa and Olsson, Niclas and Wagar, Lisa E and Medeiros, Bruno C and Meyer, Everett and Czerwinski, Debra and Khodadoust, Michael S and Zhang, Lichao and Schultz, Liora and Davis, Mark M and Elias, Joshua E and Levy, Ron
PLoS ONE, ISSN 1932-6203, 07/2019, Volume 14, Issue 7, pp. e0219547 - e0219547
Somatic mutations in cancer are a potential source of cancer specific neoantigens. Acute myeloid leukemia (AML) has common recurrent mutations shared between... 
Cellular proteins | Histocompatibility antigens | Immunotherapy | HLA histocompatibility antigens | Genetic aspects | Health aspects | Methods | Mass spectrometry | Haplotypes | Antigens | Peptides | Hematology | Myeloid leukemia | Leukemia | Oncology | Mass spectroscopy | Biology | Patients | Bearing | Medicine | Immunology | Cell lines | Ligands | Scientific imaging | Histocompatibility antigen HLA | Internet | Mutation | Acute myeloid leukemia | Cancer
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3. Full Text Chemotherapy based combinations in AML: Time to take a step back?
by Medeiros, Bruno C
Leukemia Research, ISSN 0145-2126, 10/2018, Volume 73, pp. 39 - 40
ONCOLOGY | HEMATOLOGY | ACUTE MYELOID-LEUKEMIA | Anthracyclines | Vidarabine - analogs & derivatives | Drug Therapy, Combination | Leukemia, Myeloid, Acute | Humans | Index Medicus
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4. Full Text Why do Subjects on Clinical Trials Discontinue Therapy? Do We Really Know?
by Medeiros, Bruno C., M.D and Gale, Robert Peter
Leukemia Research, ISSN 0145-2126, 2016, Volume 51, pp. 19 - 21
Hematology, Oncology and Palliative Medicine | Clinical trials | Attributions | PANEL | ONCOLOGY | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | CANCER | Medical colleges | Index Medicus
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5. Full Text Management of invasive Aspergillosis in acute myelogenous leukemia
by Medeiros, Bruno C
Clinical advances in hematology & oncology : H&O, ISSN 1543-0790, 07/2016, Volume 14, Issue 7, pp. 502 - 504
Antifungal Agents - pharmacology | Prognosis | Risk Assessment | Humans | Leukemia, Myeloid, Acute - epidemiology | Aspergillosis - diagnosis | Treatment Outcome | Azoles - therapeutic use | Azoles - pharmacology | Leukemia, Myeloid, Acute - complications | Antifungal Agents - therapeutic use | Leukemia, Myeloid, Acute - mortality | Aspergillosis - etiology | Aspergillosis - prevention & control | Disease Management | Aspergillosis - drug therapy | Index Medicus
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6. Full Text Treatment patterns in patients with acute myeloid leukemia in the United States: a cross-sectional, real-world survey
by Medeiros, Bruno C and Pandya, Bhavik J and Hadfield, Anna and Pike, James and Wilson, Samuel and Mueller, Cynthia and Bui, Cat N and Flanders, Scott C and Rider, Alex and Horvath Walsh, L. Elise
Current Medical Research and Opinion, ISSN 0300-7995, 05/2019, Volume 35, Issue 5, pp. 927 - 935
Objective: The aim of this analysis was to examine treatment patterns in patients with acute myeloid leukemia (AML) in routine clinical practice in the United... 
Adelphi Programme | real-world study | relapsed/refractory | treatment intensity | Acute myeloid leukemia | MEDICINE, RESEARCH & EXPERIMENTAL | refractory | MEDICINE, GENERAL & INTERNAL | CLINICAL-TRIALS | relapsed | OUTCOMES
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7. Full Text Polypharmacy in AML: The tip of the Iceberg
by Patel, Samit and Medeiros, Bruno C
Leukemia Research, ISSN 0145-2126, 2014, Volume 38, Issue 11, pp. 1378 - 1379
Hematology, Oncology and Palliative Medicine | Leukemia, Myeloid, Acute - drug therapy | Female | Male | Antineoplastic Agents - therapeutic use | Polypharmacy | Humans | Index Medicus
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8. Full Text Unveiling the complexity of CK+ AML
by Medeiros, Bruno C
Blood, ISSN 0006-4971, 03/2012, Volume 119, Issue 9, pp. 1958 - 1959
In acute myeloid leukemia (AML), cytogenetic abnormalities are present in more than half of patients and these chromosomal alterations are critical factors... 
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9. Full Text Effects of education and income on treatment and outcome in patientswith acute myeloid leukemia in a tax-supported health care system: A national population-based cohort study
by Østgard, Lene Sofie Granfeldt and Nørgaard, Mette and Nørgaard, Jan Maxwell and Friis, Lone Smidstrup and Schoellkopf, Claudia and Severinsen, Marianne Tang and Marcher, Claus Werenberg and Medeiros, Bruno C
Journal of Clinical Oncology, ISSN 0732-183X, 11/2017, Volume 35, Issue 32, pp. 3678 - 3687
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10. Full Text Long non-coding RNAs: Another brick in the wall of normal karyotype acute myeloid leukemia?
by Medeiros, Bruno C
Haematologica, ISSN 0390-6078, 07/2017, Volume 102, Issue 8, pp. 1301 - 1303
CLASSIFICATION | HEMATOLOGY | RECOMMENDATIONS | PROGNOSIS | EXPRESSION | Index Medicus
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11. Full Text Disparities in early death and survival in children, adolescents, and young adults with acute promyelocytic leukemia in California
: Early Death After APL in Children and AYA
by Abrahão, Renata and Ribeiro, Raul C and Medeiros, Bruno C and Keogh, Ruth H and Keegan, Theresa H.M
Cancer, ISSN 0008-543X, 11/2015, Volume 121, Issue 22, pp. 3990 - 3997
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12. Full Text Tapioca Biofilm Containing Nitrogen-doped Titanium Dioxide Nanoparticles for Electrochemical Detection of 17-[beta] Estradiol
by Mauruto de Oliveira, Gabriela C and P. de Palma, Elisangela and Kunita, Marcos H and Antigo Medeiros, Roberta and de Matos, Roberto and Francisco, Kelly Roberta and Janegitz, Bruno C
Electroanalysis, ISSN 1040-0397, 11/2017, Volume 29, Issue 11, p. 2638
A novel sensor architecture based on thin film of tapioca decorated within nitrogen-doped titanium dioxide (N-TiO.sub.2) nanoparticles is reported. The... 
Thin films | Nanoparticles | Transmission electron microscopes | Phenols | Dielectric films | Sensors | Electron microscopy | Titanium dioxide | Estradiol | Electric properties
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13. Full Text Safety and efficacy of oral panobinostat plus chemotherapy in patients aged 65 years or younger with high-risk acute myeloid leukemia
by DeAngelo, Daniel J and Walker, Alison R and Schlenk, Richard F and Sierra, Jorge and Medeiros, Bruno C and Ocio, Enrique M and Röllig, Christoph and Strickland, Stephen A and Thol, Felicitas and Valera, Sue-zette and Dasgupta, Kohinoor and Berkowitz, Noah and Stuart, Robert K
Leukemia Research, ISSN 0145-2126, 08/2019, p. 106197
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14. Full Text " It doesn't matter if you're black or white" , does it?
by Medeiros, Bruno C
Leukemia Research, ISSN 0145-2126, 02/2012, Volume 36, Issue 2, p. 127
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15. Full Text Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia
by Chan, Steven M and Thomas, Daniel and Corces-Zimmerman, M. Ryan and Xavy, Seethu and Rastogi, Suchita and Hong, Wan-Jen and Zhao, Feifei and Medeiros, Bruno C and Tyvoll, David A and Majeti, Ravindra
Nature Medicine, ISSN 1078-8956, 2015, Volume 21, Issue 2, pp. 178 - 184
Mutant isocitrate dehydrogenase (IDH) 1 and 2 proteins alter the epigenetic landscape in acute myeloid leukemia (AML) cells through production of the... 
GLIOMA-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | IDH2 MUTATIONS | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | CELL BIOLOGY | CYTOCHROME-C-OXIDASE | D-2-HYDROXYGLUTARIC ACID | INHIBITION | GROWTH | 2-HYDROXYGLUTARATE | Electron Transport | Electron Transport Complex IV - antagonists & inhibitors | Humans | Isocitrate Dehydrogenase - genetics | Sulfonamides - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Drug Resistance, Neoplasm - genetics | Leukemia, Myeloid, Acute - drug therapy | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Glutarates - metabolism | Mutation | Apoptosis | Leukemia, Myeloid, Acute - genetics | Oxidoreductases | Gene mutations | Properties | Health aspects | Medical research | Cellular biology | Leukemia | Genes | Index Medicus
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16. Full Text Report of the relapsed/refractory cohort of SWOG S0919: A phase 2 study of idarubicin and cytarabine in combination with pravastatin for acute myelogenous leukemia (AML)
by Advani, Anjali S and Li, Hongli and Michaelis, Laura C and Medeiros, Bruno C and Liedtke, Michaela and List, Alan F and O’Dwyer, Kristen and Othus, Megan and Erba, Harry P and Appelbaum, Frederick R
Leukemia Research, ISSN 0145-2126, 04/2018, Volume 67, pp. 17 - 20
Inhibition of cholesterol synthesis and uptake sensitizes acute myeloid leukemia (AML) blasts to chemotherapy. A Phase 2 study of high dose pravastatin given... 
Refractory | Idarubicin | Cytarabine | Pravastatin | Acute myeloid leukemia | Relapsed | ONCOLOGY | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | Recurrence | Cytarabine - therapeutic use | Humans | Leukemia, Myeloid, Acute - metabolism | Middle Aged | Male | Young Adult | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Cytogenetic Analysis | Idarubicin - therapeutic use | Pravastatin - therapeutic use | Leukemia, Myeloid, Acute - therapy | Risk Factors | Hematopoietic Stem Cell Transplantation | Treatment Outcome | Combined Modality Therapy | Cholesterol - metabolism | Remission Induction | Anticholesteremic Agents - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Aged | Mutation | Cohort Studies | Leukemia, Myeloid, Acute - genetics | Index Medicus | relapsed | idarubicin | refractory | cytarabine | acute myeloid leukemia | pravastatin
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17. Full Text The relationship between clinical trial accrual volume and outcomes in acute myeloid leukemia: A SWOG/ECOG-ACRIN study (S0106 and E1900)
by Medeiros, Bruno C and Othus, Megan and Tallman, Martin S and Sun, Zhuoxin and Fernandez, Hugo F and Rowe, Jacob M and Lazarus, Hillard M and Appelbaum, Frederick R and Luger, Selina M and Litzow, Mark R and Erba, Harry P
Leukemia Research, ISSN 0145-2126, 03/2019, Volume 78, pp. 29 - 33
To study whether institutional clinical trial accrual volume affects clinical outcomes of younger (age less than 61 years) patients with acute myeloid... 
AML | Clinical trial | Population-based | Volume | Leukemia | Outcomes | MORTALITY | INDUCTION | CARE | IMPACT | THERAPY | HOSPITAL VOLUME | ONCOLOGY | HEMATOLOGY | PARTICIPATION | Clinical trials | Research | Oncology, Experimental | Mortality | Cancer | volume | outcomes | population-based
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18. Full Text Facts about FCE (Fludarabine, Cytarabine, Etoposide) in Acute Myeloid Leukemia
by Medeiros, Bruno C
Acta Haematologica, ISSN 0001-5792, 05/2014, Volume 131, Issue 4, pp. 200 - 201
Editorial Comment | HEMATOLOGY | 1ST RELAPSE | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cytarabine - therapeutic use | Humans | Salvage Therapy | Leukemia, Myeloid, Acute - drug therapy | Drug Resistance, Neoplasm | Etoposide - therapeutic use | Female | Male | Vidarabine - analogs & derivatives | Vidarabine - therapeutic use | Index Medicus
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19. Full Text Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
by Stone, Richard M and Mandrekar, Sumithra J and Sanford, Ben L and Laumann, Kristina and Geyer, Susan and Bloomfield, Clara D and Thiede, Christian and Prior, Thomas W and Döhner, Hartmut and Döhner, Konstanze and Marcucci, Guido and Lo-Coco, Francesco and Klisovic, Rebecca B and Wei, Andrew and Sierra, Jorge and Sanz, Miguel A and Brandwein, Joseph M and de Witte, Theo and Niederwieser, Dietger and Appelbaum, Frederick R and Medeiros, Bruno C and Tallman, Martin S and Krauter, Jürgen and Schlenk, Richard F and Ganser, Arnold and Serve, Hubert and Ehninger, Gerhard and Amadori, Sergio and Larson, Richard A
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 5, pp. 454 - 464
Midostaurin, an oral multitargeted kinase inhibitor, is active in patients with a FLT3 mutation. Among patients with acute myeloid leukemia and this mutation,... 
TRIAL | INTERNAL TANDEM DUPLICATION | WILD-TYPE | MEDICINE, GENERAL & INTERNAL | FAVORABLE PROGNOSIS | ACUTE MYELOGENOUS LEUKEMIA | DISTINCT | TYROSINE KINASE INHIBITOR | SORAFENIB | PHASE-I | YOUNGER | Humans | Middle Aged | Kaplan-Meier Estimate | Staurosporine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Staurosporine - analogs & derivatives | Protein Kinase Inhibitors - adverse effects | Cytarabine - administration & dosage | Leukemia, Myeloid, Acute - mortality | Young Adult | fms-Like Tyrosine Kinase 3 - genetics | Protein Kinase Inhibitors - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Mutation | Daunorubicin - administration & dosage | Leukemia, Myeloid, Acute - genetics | Staurosporine - administration & dosage | Chemotherapy | Care and treatment | Myelocytic leukemia | Nonlymphoid leukemia | Research | Drug therapy | Cancer | Tyrosine | Medical research | Inhibitor drugs | Myeloid leukemia | Leukemia | Clinical trials | Oncology | Transplantation | Kinases | Patients | Cancer therapies | Survival | Cytarabine | Daunorubicin | Medical prognosis | Point mutation | Death | Remission | Acute myeloid leukemia | Protein-tyrosine kinase | Drug dosages | Index Medicus | Abridged Index Medicus
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20. Full Text Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
by M. Ryan Corces-Zimmerman and Wan-Jen Hong and Irving L. Weissman and Bruno C. Medeiros and Ravindra Majeti
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 7, pp. 2548 - 2553
Cancer is widely characterized by the sequential acquisition of genetic lesions in a single lineage of cells. Our previous studies have shown that, in acute... 
Exome | Relapse | Myeloid leukemia | Leukemia | Stem cells | Evolution | Residual neoplasm | Disease remission | Genetic mutation | Sequencing | Clonal evolution | Preleukemia | PROGENITORS | STEM-CELLS | preleukemia | clonal evolution | MULTIDISCIPLINARY SCIENCES | METHYLTRANSFERASE GENE EZH2 | DNMT3A | TET2 | CAPTURE | CANCER | SOMATIC MUTATIONS | GENOME | Antigens, CD34 - metabolism | Humans | Molecular Sequence Data | Genotype | Clonal Evolution - genetics | Mutation - genetics | Sequence Analysis, DNA | Exome - genetics | Flow Cytometry | Epigenesis, Genetic - genetics | Models, Biological | Preleukemia - genetics | Base Sequence | Hematopoietic Stem Cells - chemistry | Leukemia, Myeloid, Acute - genetics | Epigenetic inheritance | Cell research | Research | Gene mutations | Chromatin | DNA methylation | Epigenetics | Mutation | Cancer | Index Medicus | Biological Sciences
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