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Toxicology Letters, ISSN 0378-4274, 09/2014, Volume 229, pp. S10 - S10
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 11/2017, Volume 179, pp. 84 - 95
Recent developments have prompted the transition of empirically based testing of late stage toxicity in animals for a range of different endpoints including... 
Neurotoxicity | Mechanistic understanding | Key event relationship | Quantitation | Weight of evidence | Key event | Neurotoxicity Syndromes - etiology | Animals | Neurodegenerative Diseases - chemically induced | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Neurotoxicity Syndromes - metabolism | Environmental Pollutants - toxicity | Neurodegenerative Diseases - metabolism | Adverse Outcome Pathways | Toxicity Tests | Development and progression | Nervous system diseases | Index Medicus | BDNF, brain derived neurotrophic factor | MPTP, 1-methyl-4-phenyl-3104 1,2,3,6-tetrahydropyridine | ADME, absorption, distribution, metabolism and excretion | MIE, molecular initiating event | AD, Alzheimer disease | NT, neurotoxicity | WNT, Working Group of the National Coordinators for the Test Guidelines Programme | OECD, Organisation for Economic Co-operation and Development | H, Bradford-Hill | CNS, Central nervous system | WOE, weight of evidence | CI, complex I of mitochondrial chain | AOP, adverse outcome pathway | DNT, developmental neurotoxicity | PBPK, physiologically based pharmacokinetic | AOP-KB, adverse outcome pathway knowledge base | KE, key event | IATA, integrated approaches to testing and assessment | QSAR, quantitative structure activity relationship | HTT, high-throughput toxicity testing | PD, Parkinson's disease | KER, key event relationship | TFHA, Task Force for Hazard Assessment | MOA, mode of action | AO, adverse outcome
Journal Article
by Blanco‐Colino, R and Lee, S and Kamarajah, S. K and Vasko, P and Kuiper, S. Z and Farina, V and Chapman, S. J and Drake, T. M and Gavagna, L and Pasquali, S and Pata, F and Pellino, G and de la Rosa‐Estadella, M and Stellingwerf, M. E and Stijns, R. C. H and Borrellas, A and Golding, D and Ngaage, M and Van Tol, R. R and de Groof, J and de Wilt, H and Bemelman, W. A and McNamee, L and Espin‐Basany, E and Emre Baki, B and Gecim, I. E and Can Tatar, O and Bach, S and Bhangu, A and Bresges, K and Burke, J and Claireaux, H. A and Fearnhead, N and Fitzgerald, J. E and Gallagher, S and Glasbey, J. C and Gundogan, B and Harrison, E. M and Hernon, J and Khatri, C and Kong, C. Y and Lyons, A and Mohan, M and Morton, D and Pinkney, T. D and Arezzo, A and Foppa, C and Morino, M and Rubbini, M and Selvaggi, F and Sensi, B and Sica, G and Orhalmi, J and Naccari, P and Sgrò, A and Burger, B. H. C. M and Fares, D. A and Spijkerman, R and van Elst, T. R and Wiersema, R and Stassen, L. P. S and Rodriguez Garcia, R and Özkan, B. B and Tavuz, A. I and Demirci, Z. S and Baki, B. E and Choi, P. J and O'Sullivan, H and Salman, M and Simioni, A and Colombo, F and Turati, L and Cazzola, F. E and Gallo, G and Perrotta, G and Papandrea, M and Naccari, P. M and Menduni, N and Rossi, E and Chetta, N and Romeo, F and Giordano, F and Randisi, B and Curletti, G and Kuiper, J and Costa, A and Marcos Rodrigo, A and Sanchez, A and Varo Muñoz, A and Martinez Rios, C. E and Aliseda‐Jover, D and Fernandez Nieto, D and Alvarez Reyes, I and Dominguez Rodriguez, L. M and Hernandez Ros, M. I and Esteban Sinovas, O and Bartrina Soler, P and Villarejo Campos, P and Laguna Román, S and Fontanet‐Soler, S and ... and EuroSurg Collaborative
Colorectal Disease, ISSN 1462-8910, 08/2018, Volume 20, Issue 8, pp. O215 - O225
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore... 
body weight | gastrointestinal tract | digestive tract | body mass index | Postoperative complications | obesity | Body mass index | Obesity | Gastrointestinal tract | Digestive tract | Body weight | MORTALITY | SURGERY | CANCER-SURGERY | IMPACT | OBESITY PARADOX | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | Complications | Benign | Malignancy | Multivariate analysis | Patients | Ostomy | Body mass | Surgery | Body size | Adults | Gastrointestinal surgery
Journal Article