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science & technology (86) 86
life sciences & biomedicine (85) 85
phosphorylation (77) 77
biochemistry & molecular biology (70) 70
animals (67) 67
amino acid sequence (58) 58
molecular sequence data (54) 54
humans (46) 46
rats (46) 46
casein kinases (44) 44
casein kinase ii (41) 41
kinetics (41) 41
protein kinases - metabolism (41) 41
substrate specificity (41) 41
protein-serine-threonine kinases - metabolism (36) 36
biophysics (26) 26
liver - enzymology (26) 26
protein kinase ck2 (25) 25
protein phosphorylation (24) 24
binding sites (22) 22
casein kinase (21) 21
casein kinase-2 (20) 20
protein kinase (20) 20
protein kinases (20) 20
cell biology (19) 19
structure-activity relationship (19) 19
protein-serine-threonine kinases - chemistry (15) 15
casein kinase ii - metabolism (14) 14
protein binding (14) 14
recombinant proteins - metabolism (14) 14
calmodulin - metabolism (13) 13
casein kinase ii - antagonists & inhibitors (13) 13
chemistry (13) 13
models, molecular (13) 13
mutation (13) 13
peptide fragments - metabolism (12) 12
analysis (11) 11
catalytic domain (11) 11
macromolecular substances (11) 11
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protein-serine-threonine kinases - antagonists & inhibitors (11) 11
cytosol - enzymology (10) 10
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life sciences (10) 10
oligopeptides - metabolism (10) 10
pharmacology & pharmacy (10) 10
protein kinase inhibitors (10) 10
protein-serine-threonine kinases - genetics (10) 10
research (10) 10
casein kinase ii - genetics (9) 9
chemistry, medicinal (9) 9
ck2 (9) 9
casein kinase ii - chemistry (8) 8
peptides - metabolism (8) 8
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proteins (8) 8
benzimidazoles - pharmacology (7) 7
cell line (7) 7
consensus sequence (7) 7
heterocyclic compounds (7) 7
jurkat cells (7) 7
metallurgy (7) 7
mice (7) 7
organic chemistry (7) 7
sequence homology, amino acid (7) 7
adenosine triphosphate - metabolism (6) 6
apoptosis (6) 6
biochemistry, general (6) 6
calmodulin (6) 6
casein kinase 2 (6) 6
cloning, molecular (6) 6
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enzyme activation (6) 6
enzymes (6) 6
holoenzymes - metabolism (6) 6
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protein kinases - genetics (6) 6
protein kinases - isolation & purification (6) 6
protein structure, tertiary (6) 6
serine - metabolism (6) 6
zea mays - enzymology (6) 6
autophosphorylation (5) 5
base sequence (5) 5
blotting, western (5) 5
cardiology (5) 5
casein kinase-1 (5) 5
catalysis (5) 5
cells, cultured (5) 5
ck2 inhibitors (5) 5
dose-response relationship, drug (5) 5
drug design (5) 5
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inhibitory concentration 50 (5) 5
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Journal of Biological Chemistry, ISSN 0021-9258, 09/2005, Volume 280, Issue 35, pp. 31208 - 31219
Journal Article
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 2/2012, Volume 69, Issue 3, pp. 449 - 460
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 9/2003, Volume 100, Issue 18, pp. 10193 - 10200
Journal Article
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 02/2002, Volume 93, Issue 2-3, pp. 159 - 168
Casein kinase-2 (CK2) probably is the most pleiotropic member of the protein kinase family, with more than 200 substrates known to date. Unlike the great... 
Emodin | Tetrabromobenzotriazole | Flavonoids | Inhibitors | CK2 | Protein kinase | Triazoles - pharmacology | Phosphorylation | Animals | Casein Kinase II | Emodin - pharmacology | Computer Simulation | Humans | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Rats | Structure-Activity Relationship | Index Medicus
Journal Article
FEBS letters, ISSN 0014-5793, 2001, Volume 496, Issue 1, pp. 44 - 48
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of protein kinase casein kinase-2 (CK2), has been examined... 
Casein kinase | Inhibitor | Casein kinase-2 | Protein phosphorylation | Protein kinase | nCK, native casein kinase | OA, okadaic acid | PRAK, p38-regulated/activated kinase | CSK, C-terminal Src kinase | AMPK, AMP-activated protein kinase | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | MAPKAP, MAPK-activated protein kinase | p70S6K, p70 ribosomal protein S6 kinase | CK, casein kinase | SAPK, stress-activated protein kinase | PDK, 3-phosphoinositide-dependent kinase | ROCK, Rho-dependent protein kinase | CDK, cyclin-dependent kinase | G-CK, Golgi casein kinase | PKC, protein kinase C | MKK, MAPK kinase (also called MEK) | PKA, cAMP-dependent protein kinase | DRB, 1-(β-D-ribofuranosyl)-5,6-dichlorobenzimidazole | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | rCK, recombinant casein kinase | ERK, extracellular signal-regulated kinase | HS1, hematopoietic lineage cell-specific protein 1 | MSK, mitogen- and stress-activated protein kinase | TBB, 4,5,6,7-tetrabromo-2-azabenzimidazole or 4,5,6,7-tetrabromobenzotriazole | MAPK, mitogen-activated protein kinase | SGK, serum- and glucocorticoid-induced kinase | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Kinases - metabolism | Jurkat Cells - cytology | Protein Kinases - drug effects | Casein Kinase II | Emodin - pharmacology | Jurkat Cells - metabolism | Humans | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Substrate Specificity | Adenosine Triphosphate | Binding Sites - genetics | Binding, Competitive - drug effects | Triazoles - pharmacology | Triazoles - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Binding Sites - drug effects | Protein-Serine-Threonine Kinases - metabolism | Staurosporine - pharmacology | Amino Acid Substitution | Jurkat Cells - drug effects | Index Medicus
Journal Article
The FASEB journal, ISSN 1530-6860, 03/2003, Volume 17, Issue 3, pp. 349 - 368
Journal Article