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Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2003, Volume 21, Issue 23, pp. 4342 - 4349
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2008, Volume 105, Issue 24, pp. 8387 - 8392
A subset of gastrointestinal stromal tumors (GISTs) lack gain-of-function mutations in c-KIT and PDGFRα. These so-called wild-type (WT) GISTs tend to be less... 
Pediatrics | Receptors | Gastrointestinal stromal tumors | Somatomedins | Exons | Cell lines | Genetic mutation | Summarization | Tumors | Cancer | Imatinib mesylase | Adult wild-type GIST | Pediatric GIST | NYP-AEW541 | Tyrosine kinase inhibitors | CARCINOMA CELLS | MULTIDISCIPLINARY SCIENCES | adult wild-type GIST | C-KIT | FACTOR-I | ANTITUMOR-ACTIVITY | pediatric GIST | tyrosine kinase inhibitors | BREAST-CANCER | GROWTH-FACTOR RECEPTOR | imatinib mesylase | COPY NUMBER CHANGES | TYROSINE KINASE INHIBITOR | EXPRESSION | IMATINIB MESYLATE | Gastrointestinal Stromal Tumors - enzymology | RNA, Small Interfering - genetics | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Mitogen-Activated Protein Kinase Kinases - metabolism | DNA Mutational Analysis | Proto-Oncogene Proteins c-kit - genetics | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Pyrroles - therapeutic use | Gastrointestinal Stromal Tumors - genetics | Signal Transduction | Gene Silencing | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Receptor, IGF Type 1 - genetics | Pyrroles - pharmacology | Gene Amplification | Gastrointestinal Stromal Tumors - drug therapy | Pyrimidines - therapeutic use | Receptor, Platelet-Derived Growth Factor alpha - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Benzamides | Mutation | Apoptosis | Immunohistochemistry | Prevention | Usage | Care and treatment | Gastrointestinal tumors | Genetic aspects | Research | Insulin-like growth factor 1 | Health aspects | Methods | Risk factors | Ribonucleic acid--RNA | Comparative analysis | Insulin | Cells | Index Medicus | Biological Sciences
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 06/2013, Volume 11, Issue 6, pp. 557 - 567
Telomere maintenance is an essential characteristic of cancer cells, most commonly achieved by activation of telomerase. Telomeres can also be maintained by a... 
MAINTENANCE | CELLS | RECOMBINATION | ONCOLOGY | LIPOSARCOMAS | DNA | LENGTH | MECHANISMS | ABSENCE | CELL BIOLOGY | Models, Biological | Humans | Cell Line, Tumor | Telomeric Repeat Binding Protein 1 - metabolism | Telomerase - metabolism | Telomere - metabolism | Inclusion Bodies - metabolism | Nucleic Acid Conformation | Telomere Homeostasis | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2002, Volume 347, Issue 7, pp. 472 - 480
Journal Article
Genes, Chromosomes and Cancer, ISSN 1045-2257, 02/2013, Volume 52, Issue 2, pp. 214 - 224
Approximately 15% of gastrointestinal stromal tumors (GISTs) in adults and 85% in children lack mutations in KIT and PDGFRA and are known as wild‐type GISTs.... 
V600E BRAF MUTATIONS | CARNEY TRIAD | SUCCINATE-DEHYDROGENASE | ONCOLOGY | COPY NUMBER | GENETICS & HEREDITY | GERMLINE MUTATIONS | DEHYDROGENASE-DEFICIENT GISTS | POTENTIAL THERAPEUTIC TARGET | OF-FUNCTION MUTATIONS | INVERSION PROBE ASSAY | PULMONARY CHONDROMA | Immunohistochemistry | Receptor, IGF Type 1 - metabolism | Gastrointestinal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Proto-Oncogene Proteins c-kit - metabolism | Young Adult | DNA Mutational Analysis | Base Sequence | Aged, 80 and over | Adult | Female | Proto-Oncogene Proteins c-kit - genetics | Gastrointestinal Stromal Tumors - genetics | Proto-Oncogene Proteins B-raf - metabolism | Gastrointestinal Neoplasms - metabolism | Electron Transport Complex II - genetics | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Receptor, IGF Type 1 - genetics | Succinate Dehydrogenase - genetics | Electron Transport Complex II - metabolism | Proto-Oncogene Proteins B-raf - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adolescent | Gastrointestinal Stromal Tumors - metabolism | Succinate Dehydrogenase - metabolism | Aged | Mutation | Platelet-derived growth factor | Gene mutations | Genes | Genomics | Genetic aspects | Tumors | Index Medicus
Journal Article
Journal Article