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PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201690
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2018, Volume 118, Issue 2, pp. 340 - 350
Abstract Coagulation factor XI is activated by thrombin or factor XIIa resulting in a conformational change that converts the catalytic domain into its active... 
Coagulation and Fibrinolysis | mass spectrometry | factor XI | conformational change | chemical footprinting | BLOOD-COAGULATION | CRYSTAL-STRUCTURE | COAGULATION-FACTOR-XI | THROMBIN GENERATION | FXIA CATALYTIC DOMAIN | PLASMA PREKALLIKREIN | AMINO-ACIDS | FACTOR-IX | BINDING-SITE | PERIPHERAL VASCULAR DISEASE | PROTEASE INHIBITOR DOMAIN | HEMATOLOGY
Journal Article
Human mutation, ISSN 1059-7794, 2017, Volume 38, Issue 10, pp. 1402 - 1411
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2018, Volume 475, Issue 17, pp. 2819 - 2830
Journal Article
Journal of Proteomics, ISSN 1874-3919, 02/2019, Volume 192, pp. 89 - 101
The vascular endothelium provides a unique interaction plane for plasma proteins and leukocytes in inflammation. The pro-inflammatory cytokines Tumor Necrosis... 
Cell surface proteomics | TNFα | Phosphoproteomics | Proteomics | Inflammation | IL-1β | Endothelium | ACTIVATION | TNF alpha | PROTEIN | BIOCHEMICAL RESEARCH METHODS | IL-1 beta | ICAM-1 | CELL-ADHESION MOLECULE-1 | MESSENGER-RNA | CLONING | SURFACE | EXTRACELLULAR-MATRIX | TNF-ALPHA | EXPRESSION
Journal Article
Journal of Proteomics, ISSN 1874-3919, 02/2019, Volume 192, p. 89
The vascular endothelium provides a unique interaction plane for plasma proteins and leukocytes in inflammation. The pro-inflammatory cytokines Tumor Necrosis... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2638 - 2638
Abstract Background Platelet concentrates (PCs) are stored at room temperature to preserve their biological activity. To minimize the risk of bacterial... 
Journal Article
Haematologica, ISSN 0390-6078, 07/2019, Volume 104, Issue 7, pp. 1460 - 1472
Dominant-negative mutations in the transcription factor Growth Factor Independence-1B (GFI1B), such as GFI1B Q287* , cause a bleeding disorder characterized by... 
Journal Article
Blood, ISSN 0006-4971, 08/2012, Volume 120, Issue 9, pp. 1761 - 1763
In this issue of Blood, Gilbert and colleagues present an elegant study on the membrane-interactive domains of factors VIII (FVIII) and V (FV).(1) The... 
HEMATOLOGY | HUMAN-PLATELETS | Protein Structure, Tertiary | Animals | Humans | Factor VIII - chemistry | Phospholipids - chemistry | Factor V - chemistry | Mutation
Journal Article
Hemoglobin, ISSN 0363-0269, 03/2019, Volume 43, Issue 2, pp. 77 - 82
A 4-year-old boy, a β-thalassemia (β-thal) carrier, with an unexplained severe chronic microcytic anemia was referred to us. Sequencing of the α-globin genes... 
β-thalassemia (β-thal) | Hb Charlieu | α-Thalassemia (α-thal) | anemia | hemoglobin (Hb) | erythrocyte | BIOCHEMISTRY & MOLECULAR BIOLOGY | beta-thalassemia (beta-thal) | HEMATOLOGY | alpha-Thalassemia (alpha-thal) | ALPHA-GLOBIN
Journal Article
Journal of thrombosis and haemostasis : JTH, 09/2019
Factor XI (FXI) is a zymogen in the coagulation pathway that, once activated, promotes haemostasis by activating factor IX (FIX). Substitution studies using... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 489 - 489
Abstract Abstract 489 Autoantibodies directed against ADAMTS13 prohibit the processing of VWF multimers initiating a rare and life-threatening disorder called... 
Journal Article
by Tuijnenburg, Paul and Lango Allen, Hana and Burns, Siobhan O and Burns, Siobhan and Greene, Daniel and Jansen, Machiel H and Staples, Emily and Stephens, Jonathan and Carss, Keren J and Carss, Keren and Biasci, Daniele and Baxendale, Helen and Thomas, Moira and Chandra, Anita and Kiani-Alikhan, Sorena and Longhurst, Hilary and Longhurst, Hilary J and Seneviratne, Suranjith and Seneviratne, Suranjith L and Oksenhendler, Eric and Simeoni, Ilenia and de Bree, Godelieve J and Tool, Anton T.J and van Leeuwen, Ester M.M and Ebberink, Eduard H.T.M and Meijer, Alexander B and Tuna, Salih and Whitehorn, Deborah and Brown, Matthew and Turro, Ernest and Thrasher, Adrian and Thrasher, Adrian J and Smith, Kenneth G.C and Thaventhiran, James E and Thaventhiran, James and Kuijpers, Taco W and Kuijpers, Taco and Adhya, Zoe and Alachkar, Hana and Anantharachagan, Ariharan and Antrobus, Richard and Arumugakani, Gururaj and Bacchelli, Chiara and Bethune, Claire and Bibi, Shahnaz and Boardman, Barbara and Booth, Claire and Browning, Michael and Brownlie, Mary and Clifford, Hayley and Cooper, Nichola and Davies, Sophie and Dempster, John and Devlin, Lisa and Doffinger, Rainer and Drewe, Elizabeth and Edgar, David and Egner, William and El-Shanawany, Tariq and Gaspar, Bobby and Ghurye, Rohit and Gilmour, Kimberley and Goddard, Sarah and Gordins, Pavel and Grigoriadou, Sofia and Hackett, Scott and Hague, Rosie and Harper, Lorraine and Hayman, Grant and Herwadkar, Archana and Hughes, Stephen and Huissoon, Aarnoud and Jolles, Stephen and Jones, Julie and Kelleher, Peter and Klein, Nigel and Kumararatne, Dinakantha and Laffan, James and Lear, Sara and Lorenzo, Lorena and Maimaris, Jesmeen and Manson, Ania and McDermott, Elizabeth and Millar, Hazel and Mistry, Anoop and Morrisson, Valerie and Murng, Sai and Nasir, Iman and Nejentsev, Sergey and Noorani, Sadia and Ponsford, Mark and Qasim, Waseem and Quinn, Ellen and Quinti, Isabella and Richter, Alex and Samarghitean, Crina and Sargur, Ravishankar and Savic, Sinisa and Sewall, Carrock and Shackley, Fiona and ... and NIHR BioResource-Rare Dis and NIHR BioResource–Rare Diseases Consortium
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 10/2018, Volume 142, Issue 4, pp. 1285 - 1296
Journal Article