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1. Full Text Diagnostic Accuracy of 64-Slice Computed Tomography Coronary Angiography. A Prospective, Multicenter, Multivendor Study
by Meijboom, W. Bob and Meijs, Matthijs F.L and Schuijf, Joanne D and Cramer, Maarten J and Mollet, Nico R and van Mieghem, Carlos A.G and Nieman, Koen and van Werkhoven, Jacob M and Pundziute, Gabija and Weustink, Annick C and de Vos, Alexander M and Pugliese, Francesca and Rensing, Benno and Jukema, J. Wouter and Bax, Jeroen J and Prokop, Mathias and Doevendans, Pieter A and Hunink, Myriam G.M and Krestin, Gabriel P and de Feyter, Pim J
Journal of the American College of Cardiology, ISSN 0735-1097, 2008, Volume 52, Issue 25, pp. 2135 - 2144
Objectives: This study sought to determine the diagnostic accuracy of 64-slice computed tomographic coronary angiography (CTCA) to detect or rule out... 
computed tomography | coronary artery disease | coronary angiography | prospective | multicenter | Predictive Value of Tests | Confidence Intervals | Prevalence | Prospective Studies | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Coronary Artery Disease - diagnostic imaging | Coronary Angiography - methods | Coronary Artery Disease - physiopathology | Sensitivity and Specificity | Female | Aged | Studies | Accuracy | Heart attacks | Coronary vessels | Scanners | Cardiovascular disease | Angina pectoris | Acute coronary syndromes
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2. Full Text Diagnostic Accuracy of 64-Slice Computed Tomography Coronary Angiography
by Meijboom, W. Bob, MD and Meijs, Matthijs F.L., MD and Schuijf, Joanne D., MD, PhD and Cramer, Maarten J., MD, PhD and Mollet, Nico R., MD, PhD and van Mieghem, Carlos A.G., MD and Nieman, Koen, MD, PhD and van Werkhoven, Jacob M., MD and Pundziute, Gabija, MD and Weustink, Annick C., MD and de Vos, Alexander M., MD and Pugliese, Francesca, MD and Rensing, Benno, MD, PhD and Jukema, J. Wouter, MD, PhD and Bax, Jeroen J., MD, PhD and Prokop, Mathias, MD, PhD and Doevendans, Pieter A., MD, PhD and Hunink, Myriam G.M., MD, PhD and Krestin, Gabriel P., MD, PhD and de Feyter, Pim J., MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 52, Issue 25, pp. 2135 - 2144
Objectives This study sought to determine the diagnostic accuracy of 64-slice computed tomographic coronary angiography (CTCA) to detect or rule out... 
Cardiovascular | Internal Medicine | coronary artery disease | computed tomography | coronary angiography | prospective | multicenter | CARDIAC & CARDIOVASCULAR SYSTEMS | STENOSIS | METAANALYSIS | CARDIOLOGY | PERFORMANCE | prospective y multicenter | COMMITTEE | CT ANGIOGRAPHY | PATIENT | RADIOLOGY | ARTERY-DISEASE | CT imaging | Diagnostic imaging | Diagnosis | Cardiology | Coronary heart disease | Medical equipment | Angiography | Epidemiology | Physiological apparatus
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3. Full Text A clinical prediction rule for the diagnosis of coronary artery disease: Validation, updating, and extension
by Genders, Tessa S.S and Steyerberg, Ewout W and Alkadhi, Hatem and Leschka, Sebastian and Desbiolles, Lotus and Nieman, Koen and Galema, Tjebbe W and Meijboom, W. Bob and Mollet, Nico R and De Feyter, Pim J and Cademartiri, Filippo and Maffei, Erica and Dewey, Marc and Zimmermann, Elke and Laule, Michael and Pugliese, Francesca and Barbagallo, Rossella and Sinitsyn, Valentin and Bogaert, Jan and Goetschalckx, Kaatje and Schoepf, U. Joseph and Rowe, Garrett W and Schuijf, Joanne D and Bax, Jeroen J and De Graaf, Fleur R and Knuuti, Juhani and Kajander, Sami and Van Mieghem, Carlos A.G and Meijs, Matthijs F.L and Cramer, Maarten J and Gopalan, Deepa and Feuchtner, Gudrun and Friedrich, Guy and Krestin, Gabriel P and Hunink, M.G. Myriam and CAD Consortium and The CAD Consortium
European Heart Journal, ISSN 0195-668X, 06/2011, Volume 32, Issue 11, pp. 1316 - 1330
Aims The aim was to validate, update, and extend the Diamond-Forrester model for estimating the probability of obstructive coronary artery disease (CAD) in a... 
Validation | Stable chest pain | Angina pectoris | Coronary artery disease | Prediction model | Pre-test probability | CARDIAC & CARDIOVASCULAR SYSTEMS | AMERICAN-COLLEGE | RISK | COMMITTEE | COMPUTED-TOMOGRAPHY | RECLASSIFICATION | PROBABILITY | ANGIOGRAPHY-AND-INTERVENTIONS | Predictive Value of Tests | Prospective Studies | Risk Assessment | Humans | Middle Aged | Decision Support Techniques | Probability | Male | Calibration | Aged, 80 and over | Adult | Female | ROC Curve | Aged | Early Diagnosis | Angina, Stable - etiology | Coronary Stenosis - diagnosis
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4. Full Text Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syndrome in patients suspected of coronary artery disease
by Gorter, Petra M and van Lindert, Anne S.R and de Vos, Alexander M and Meijs, Matthijs F.L and van der Graaf, Yolanda and Doevendans, Pieter A and Prokop, Mathias and Visseren, Frank L.J
Atherosclerosis, ISSN 0021-9150, 2007, Volume 197, Issue 2, pp. 896 - 903
Abstract Objective Adipose tissue surrounding coronary arteries may contribute to the development of coronary atherosclerosis given its localisation and... 
Cardiovascular | Cardiac computed tomography | Metabolic syndrome | Reproducibility | Coronary artery disease | Peri-coronary fat | Epicardial adipose tissue | coronary artery disease | DIAGNOSIS | cardiac computed tomography | reproducibility | PIGS IN-VIVO | RISK | CLASSIFICATION | LESIONS | metabolic syndrome | peri-coronary fat | IMPACT | INSULIN-RESISTANCE | MEN | CARDIOVASCULAR-DISEASE | epicardial adipose tissue | PERIPHERAL VASCULAR DISEASE | ADIPOSE-TISSUE | Obesity | Reproducibility of Results | Coronary Vessels - physiopathology | Humans | Middle Aged | Adipose Tissue - pathology | Male | Adipose Tissue - diagnostic imaging | Tomography, Spiral Computed | Metabolic Syndrome - complications | Coronary Angiography | Coronary Artery Disease - diagnostic imaging | Coronary Artery Disease - physiopathology | Female | Aged | CT imaging | Coronary heart disease | Cardiac patients | Atherosclerosis
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5. Full Text Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci
by Tragante, Vinicius and Barnes, Michael R and Ganesh, Santhi K and Lanktree, Matthew B and Guo, Xiuqing and Guo, Wei and Franceschini, Nora and Smith, Erin N and Johnson, Andrew D and Johnson, Julie A and Johnson, Toby and Holmes, Michael V and Padmanabhan, Sandosh and Karczewski, Konrad J and Almoguera, Berta and Barnard, John and Baumert, Jens and Chang, Yen-Pei Christy and Elbers, Clara C and Farrall, Martin and Fischer, Mary E and Gaunt, Tom R and Gho, Johannes M.I.H and Gieger, Christian and Goel, Anuj and Gong, Yan and Isaacs, Aaron and Kleber, Marcus E and Leach, Irene Mateo and McDonough, Caitrin W and Meijs, Matthijs F.L and Melander, Olle and Nelson, Christopher P and Nolte, Ilja M and Pankratz, Nathan and Price, Tom S and Shaffer, Jonathan and Shah, Sonia and Tomaszewski, Maciej and van der Most, Peter J and Van Iperen, Erik P.A and Vonk, Judith M and Witkowska, Kate and Wong, Caroline O.L and Zhang, Li and Beitelshees, Amber L and Berenson, Gerald S and Bhatt, Deepak L and Brown, Morris and Burt, Amber and Cooper-DeHoff, Rhonda M and Connell, John M and Cruickshanks, Karen J and Curtis, Sean P and Davey-Smith, George and Delles, Christian and Gansevoort, Ron T and Haiqing, Shen and Hastie, Claire E and Hofker, Marten H and Hovingh, G. Kees and Kim, Daniel S and Kirkland, Susan A and Klein, Barbara E and Klein, Ronald and Li, Yun R and Maiwald, Steffi and Newton-Cheh, Christopher and O’Brien, Eoin T and Onland-Moret, N. Charlotte and Palmas, Walter and Parsa, Afshin and Penninx, Brenda W and Pettinger, Mary and Vasan, Ramachandran S and Ranchalis, Jane E and M Ridker, Paul and Rose, Lynda M and Sever, Peter and Shimbo, Daichi and Steele, Laura and Stolk, Ronald P and Thorand, Barbara and Trip, Mieke D and van Duijn, Cornelia M and Verschuren, W. Monique and Wijmenga, Cisca and Wyatt, Sharon and Young, J. Hunter and Zwinderman, Aeilko H and Bezzina, Connie R and Boerwinkle, Eric and Casas, Juan P and Caulfield, Mark J and Chakravarti, Aravinda and Chasman, Daniel I and Davidson, Karina W and Doevendans, Pieter A and Dominiczak, Anna F and FitzGerald, Garret A and ... and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and EpiHealth: Epidemiology for Health and Lund University and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 03/2014, Volume 94, Issue 3, pp. 349 - 360
Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean... 
COMMON VARIANTS | CANDIDATE GENES | DRUG DISCOVERY | GENETICS & HEREDITY | HUMAN PREFRONTAL CORTEX | FACTOR-KAPPA-B | ESSENTIAL-HYPERTENSION | SUSCEPTIBILITY LOCUS | PULSE PRESSURE | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | Blood Pressure | Genetics, Population | Computational Biology - methods | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Diastole | Europe | Humans | Risk Factors | Genotype | Genetic Loci | Systole | Phenotype | Arterial Pressure | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Quality Control | Quantitative trait loci | Physiological aspects | Genetic research | Blood pressure | Genetic aspects | Research | Identification and classification | Meta-analysis | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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6. Full Text Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
by Asselbergs, Folkert W and Guo, Yiran and van Iperen, Erik P.A and Sivapalaratnam, Suthesh and Tragante, Vinicius and Lanktree, Matthew B and Lange, Leslie A and Almoguera, Berta and Appelman, Yolande E and Barnard, John and Baumert, Jens and Beitelshees, Amber L and Bhangale, Tushar R and Chen, Yii-Der Ida and Chen, Wei and Gaunt, Tom R and Gong, Yan and Hopewell, Jemma C and Johnson, Toby and Johnson, Julie A and Kleber, Marcus E and Langaee, Taimour Y and Li, Mingyao and Li, Yun R and Liu, Kiang and McDonough, Caitrin W and Meijs, Matthijs F.L and Middelberg, Rita P.S and Musunuru, Kiran and Nelson, Christopher P and O’Connell, Jeffery R and Padmanabhan, Sandosh and Pankow, James S and Pankratz, Nathan and Rafelt, Suzanne and Rajagopalan, Ramakrishnan and Romaine, Simon P.R and Schork, Nicholas J and Shaffer, Jonathan and Shen, Haiqing and Smith, Erin N and Tischfield, Sam E and van der Most, Peter J and van Vliet-Ostaptchouk, Jana V and Verweij, Niek and Volcik, Kelly A and Zhang, Li and Bailey, Kristian M and Bailey, Kent R and Bauer, Florianne and Boer, Jolanda M.A and Braund, Peter S and Burt, Amber and Burton, Paul R and Buxbaum, Sarah G and Cooper-DeHoff, Rhonda M and Cupples, L. Adrienne and deJong, Jonas S and Delles, Christian and Duggan, David and Fornage, Myriam and Furlong, Clement E and Glazer, Nicole and Gums, John G and Hastie, Claire and Holmes, Michael V and Illig, Thomas and Kirkland, Susan A and Kivimaki, Mika and Klein, Barbara E and Klein, Ronald and Kooperberg, Charles and Kottke-Marchant, Kandice and Kumari, Meena and LaCroix, Andrea Z and Mallela, Laya and Murugesan, Gurunathan and Ordovas, Jose and Ouwehand, Willem H and Post, Wendy S and Saxena, Richa and Scharnagl, Hubert and Schreiner, Pamela J and Shah, Tina and Shields, Denis C and Shimbo, Daichi and Srinivasan, Sathanur R and Stolk, Ronald P and Swerdlow, Daniel I and Taylor, Herman A and Topol, Eric J and Toskala, Elina and van Pelt, Joost L and van Setten, Jessica and Yusuf, Salim and Whittaker, John C and Zwinderman, A.H and Anand, Sonia S and Balmforth, Anthony J and Berenson, Gerald S and ... and LifeLines Cohort Study and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and EpiHealth: Epidemiology for Health and Lund University and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 11/2012, Volume 91, Issue 5, pp. 823 - 838
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated... 
DENSITY-LIPOPROTEIN CHOLESTEROL | FAMILIAL HYPERCHOLESTEROLEMIA | QUANTITATIVE TRAITS | APOLIPOPROTEIN B-100 | GENETICS & HEREDITY | MISSING HERITABILITY | CORONARY-HEART-DISEASE | COMPLEX TRAITS | GENOME-WIDE ASSOCIATION | PLASMA TRIGLYCERIDES | STATISTICAL-MODEL | Genome-Wide Association Study | Lipids - genetics | Humans | European Continental Ancestry Group | Genotype | Male | Cholesterol, HDL - genetics | Cholesterol, LDL - genetics | Phenotype | Lipids - blood | Sex Factors | Triglycerides - blood | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Female | Polymorphism, Single Nucleotide | Triglycerides - genetics | Quantitative Trait Loci | Europeans | Usage | Genome-wide association studies | Genetic variation | Cholesterol, HDL | Multifactorial traits | Genetic aspects | Research | Health aspects | Genetic screening | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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7. Full Text Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
by Saxena, Richa and Elbers, Clara C and Guo, Yiran and Peter, Inga and Gaunt, Tom R and Mega, Jessica L and Lanktree, Matthew B and Tare, Archana and Castillo, Berta Almoguera and Li, Mingyao and Li, Yun R and Johnson, Julie A and Johnson, Toby and Bruinenberg, Marcel and Gilbert-Diamond, Diane and Rajagopalan, Ramakrishnan and Voight, Benjamin F and Balasubramanyam, Ashok and Barnard, John and Bauer, Florianne and Baumert, Jens and Bhangale, Tushar and Böhm, Bernhard O and Braund, Peter S and Burton, Paul R and Chandrupatla, Hareesh R and Clarke, Robert and Cooper-DeHoff, Rhonda M and Crook, Errol D and Davey-Smith, George and Day, Ian N and de Boer, Anthonius and de Groot, Mark C.H and Drenos, Fotios and Ferguson, Jane and Fox, Caroline S and Furlong, Clement E and Gibson, Quince and Gieger, Christian and Gilhuijs-Pederson, Lisa A and Glessner, Joseph T and Goel, Anuj and Gong, Yan and Grant, Struan F.A and Grobbee, Diederick E and Hastie, Claire and Humphries, Steve E and Kim, Cecilia E and Kivimaki, Mika and Kleber, Marcus and Meisinger, Christa and Kumari, Meena and Langaee, Taimour Y and Lawlor, Debbie A and Lobmeyer, Maximilian T and Maitland-van der Zee, Anke-Hilse and Meijs, Matthijs F.L and Molony, Cliona M and Morrow, David A and Murugesan, Gurunathan and Musani, Solomon K and Nelson, Christopher P and Newhouse, Stephen J and O'Connell, Jeffery R and Padmanabhan, Sandosh and Palmen, Jutta and Patel, Sanjey R and Pepine, Carl J and Pettinger, Mary and Price, Thomas S and Rafelt, Suzanne and Ranchalis, Jane and Rasheed, Asif and Rosenthal, Elisabeth and Ruczinski, Ingo and Shah, Sonia and Shen, Haiqing and Silbernagel, Günther and Smith, Erin N and Spijkerman, Annemieke W.M and Stanton, Alice and Steffes, Michael W and Thorand, Barbara and Trip, Mieke and van der Harst, Pim and van der A, Daphne L and van Iperen, Erik P.A and van Setten, Jessica and van Vliet-Ostaptchouk, Jana V and Verweij, Niek and Wolffenbuttel, Bruce H.R and Young, Taylor and Zafarmand, M. Hadi and Zmuda, Joseph M and Boehnke, Michael and Altshuler, David and McCarthy, Mark and Kao, W.H. Linda and Pankow, James S and Cappola, Thomas P and ... and PROCARDIS and Diagram Consortium and ASCOT Investigators and Look AHEAD Res Grp and Look AHEAD Research Group and DIAGRAM consortium and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and EpiHealth: Epidemiology for Health and Lund University and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 03/2012, Volume 90, Issue 3, pp. 410 - 425
To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale meta-analyses by using a custom ∼50,000 SNP genotyping array (the... 
COMMON VARIANTS | POPULATION | RISK LOCI | INSULIN-RESISTANCE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | EUROPEAN AMERICANS | AFRICAN-AMERICANS | SNP ARRAY | BLOOD-PRESSURE | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Follow-Up Studies | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Genotype | Male | Genetic Loci | Case-Control Studies | Young Adult | Diabetes Mellitus, Type 2 - ethnology | Ethnic Groups | Adolescent | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Reviews | Genotyping | Diabetes mellitus | Ethnic groups | Clinical trials | Population studies | Single-nucleotide polymorphism | Genetic factors | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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8. Full Text Relation of Epicardial and Pericoronary Fat to Coronary Atherosclerosis and Coronary Artery Calcium in Patients Undergoing Coronary Angiography
by Gorter, Petra M., MD, PhD and de Vos, Alexander M., MD and van der Graaf, Yolanda, MD, PhD and Stella, Pieter R., MD and Doevendans, Pieter A., MD, PhD and Meijs, Matthijs F.L., MD and Prokop, Mathias, MD, PhD and Visseren, Frank L.J., MD, PhD
American Journal of Cardiology, The, ISSN 0002-9149, 2008, Volume 102, Issue 4, pp. 380 - 385
Fat surrounding coronary arteries might aggravate coronary artery disease (CAD). We investigated the relation between epicardial adipose tissue (EAT) and... 
Cardiovascular | METABOLIC SYNDROME | OBESITY | CARDIAC & CARDIOVASCULAR SYSTEMS | QUANTIFICATION | PIGS IN-VIVO | CARDIOVASCULAR-DISEASE | RISK | CLASSIFICATION | COMPUTED-TOMOGRAPHY | REPRODUCIBILITY | ADIPOSE-TISSUE | Body Mass Index | Severity of Illness Index | Calcinosis - diagnosis | Coronary Vessels - pathology | Cross-Sectional Studies | Humans | Middle Aged | Risk Factors | Male | Tomography, X-Ray Computed | Angina Pectoris - etiology | Disease Progression | Calcinosis - epidemiology | Coronary Angiography | Pericardium - pathology | Adiposity | Coronary Artery Disease - diagnosis | Coronary Artery Disease - complications | Coronary Artery Disease - pathology | Female | Calcinosis - pathology | Angiography | Coronary heart disease | Cardiac patients | Body weight | Atherosclerosis
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9. Full Text Targeted Deletion of Nuclear Factor κB p50 Enhances Cardiac Remodeling and Dysfunction Following Myocardial Infarction
by Timmers, Leo and van Keulen, J Karlijn and Hoefer, Imo E and Meijs, Matthijs F.L and van Middelaar, Ben and den Ouden, Krista and van Echteld, Cees J.A and Pasterkamp, Gerard and de Kleijn, Dominique P.V
Circulation Research, ISSN 0009-7330, 03/2009, Volume 104, Issue 5, pp. 699 - 706
Myocardial infarction is commonly complicated by left ventricular remodeling, a process that leads to cardiac dilatation, congestive heart failure and death.... 
Ischemic heart disease | Myocardial infarction | NF-κB | Wound healing | Remodeling | SURVIVAL | remodeling | wound healing | CARDIAC & CARDIOVASCULAR SYSTEMS | myocardial infarction | HEART-FAILURE | ischemic heart disease | MYOCYTE | NF-kappa B | IN-VIVO | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | BLOCKADE | HEMATOLOGY | MATRIX-METALLOPROTEINASE INHIBITION | EXPRESSION
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