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Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 10 - 14
The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation... 
PLATFORM | VARIANTS | CLUSTERS | CURATION | PROTEIN FUNCTION | MULTIDISCIPLINARY SCIENCES | Phenotypes | Websites | Molecular interactions | Phenotypic variations | Amino acid sequence | Data processing | Amino acids | Proteins | Consortia | Datasets | Annotations | Mutation | Protein interaction | Dinàmica molecular | Genoma humà | Life Sciences | Biomolecules | Biochemistry, Molecular Biology
Journal Article
by Jiang, Yuxiang and Oron, Tal Ronnen and Clark, Wyatt T and Bankapur, Asma R and Anea, D', Daniel and Lepore, Rosalba and Funk, Christopher S and Kahanda, Indika and Verspoor, Karin M and Ben-Hur, Asa and Koo, Da Chen Emily and Penfold-Brown, Duncan and Shasha, Dennis and Youngs, Noah and Bonneau, Richard and Lin, Alexana and Sahraeian, Sayed M.E and Martelli, Pier Luigi and ti, Giuseppe and Casadio, Rita and Cao, Renzhi and Zhong, Zhaolong and Cheng, Jianlin and Altenhoff, Aian and Skunca, Nives and Dessimoz, Christophe and Dogan, Tunca and Hakala, Kai and Kaewphan, Suwisa and Mehryary, Farrokh and Salakoski, Tapio and Ginter, Filip and Fang, Hai and Smithers, Ben and Oates, Matt and Gough, Julian and Törönen, Petri and Koskinen, Patrik and Holm, Liisa and Chen, Ching Tai and Hsu, Wen Lian and Bryson, Kevin and Cozzetto, Domenico and Minneci, Federico and Jones, David T and Chapman, Samuel and BKC, Dukka and Khan, Ishita K and Kihara, Daisuke and Ofer, Dan and Rappoport, Nadav and Stern, Amos and Cibrian-Uhalte, Elena and Denny, Paul and Foulger, Rebecca E and Hieta, Reija and Legge, Duncan and Lovering, Ruth C and Magrane, Michele and Melidoni, Anna N and Mutowo-Meullenet, Prudence and Pichler, Klemens and Shypitsyna, Aleksana and Li, Biao and Zakeri, Pooya and ElShal, Sarah and Tranchevent, Léon Charles and Das, Sayoni and Dawson, Natalie L and Lee, David and Lees, Jonathan G and Sillitoe, Ian and Bhat, Prajwal and Nepusz, Tamás and Romero, Alfonso E and Sasidharan, Rajkumar and Yang, Haixuan and Paccanaro, Alberto and Gillis, Jesse and Sedeño-Cortés, Aiana E and Pavlidis, Paul and Feng, Shou and Cejuela, Juan M and Goldberg, Tatyana and Hamp, Tobias and Richter, Lothar and Salamov, Asaf and Gabaldon, Toni and Marcet-Houben, Marina and Supek, Fran and Gong, Qingtian and Ning, Wei and Zhou, Yuanpeng and Tian, Weidong and Falda, Marco and Fontana, Paolo and Lavezzo, Enrico and Toppo, Stefano and Ferrari, Carlo and Giollo, Manuel and ...
Genome Biology, ISSN 1474-7596, 2016, Volume 17, Issue 1, p. 184
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2015, Volume 43, Issue 1, pp. D479 - D484
The IntAct molecular interaction database has created a new, free, open-source, manually curated resource, the Complex Portal (www.ebi.ac.uk/intact/complex),... 
ONTOLOGY | DATABASE | CURATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOURCE | Proteins - genetics | Animals | Macromolecular Substances - chemistry | Proteins - metabolism | Databases, Protein | Humans | Protein Binding | Mice | Internet | Proteins - chemistry | Binding Sites | Database Issue
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2015, Volume 96, Issue 3, pp. 267 - 277
Journal Article
Journal Article
by Carbon, S and Dietze, H and Lewis, S.E and Mungall, C.J and Munoz-Torres, M.C and Basu, S and Chisholm, R.L and Dodson, R.J and Fey, P and Thomas, Paul D and Mi, H and Muruganujan, A and Huang, X and Poudel, S and Hu, J.C and Aleksander, S.A and McIntosh, B.K and Renfro, D.P and Siegele, D.A and Antonazzo, G and Attrill, H and Brown, N.H and Marygold, S.J and Mc-Quilton, P and Ponting, L and Millburn, G.H and Rey, A.J and Stefancsik, R and Tweedie, S and Falls, K and Schroeder, A.J and Courtot, M and Osumi-Sutherland, D and Parkinson, H and Roncaglia, P and Lovering, R.C and Foulger, R.E and Huntley, R.P and Denny, P and Campbell, N.H and Kramarz, B and Patel, S and Buxton, J.L and Umrao, Z and Deng, A.T and Alrohaif, H and Mitchell, K and Ratnaraj, F and Omer, W and Rodríguez-López, M and C. Chibucos, M and Giglio, M and Nadendla, S and Duesbury, M.J and Koch, M and Meldal, B.H.M and Melidoni, A and Porras, P and Orchard, S and Shrivastava, A and Chang, H.Y and Finn, R.D and Fraser, M and Mitchell, A.L and Nuka, G and Potter, S and Rawlings, N.D and Richardson, L and Sangrador-Vegas, A and Young, S.Y and Blake, J.A and Christie, K.R and Dolan, M.E and Drabkin, H.J and Hill, D.P and Ni, L and Sitnikov, D and Harris, M.A and Hayles, J and Oliver, S.G and Rutherford, K and Wood, V and Bahler, J and Lock, A and De Pons, J and Dwinell, M and Shimoyama, M and Laulederkind, S and Hayman, G.T and Tutaj, M and Wang, S.-J and D'Eustachio, P and Matthews, L and Balhoff, J.P and Balakrishnan, R and Binkley, G and Cherry, J.M and Costanzo, M.C and Engel, S.R and Miyasato, S.R and ...
Nucleic Acids Research, ISSN 0305-1048, 01/2017, Volume 45, Issue 1, pp. D331 - D338
Journal Article
by Carbon, S and Dietze, H and Lewis, SE and Mungall, CJ and Munoz-Torres, MC and Basu, S and Chisholm, RL and Dodson, RJ and Fey, P and Thomas, PD and Mi, H and Muruganujan, A and Huang, X and Poudel, S and Hu, JC and Aleksander, SA and McIntosh, BK and Renfro, DP and Siegele, DA and Antonazzo, G and Attrill, H and Brown, NH and Marygold, SJ and McQuilton, P and Ponting, L and Millburn, GH and Rey, AJ and Stefancsik, R and Tweedie, S and Falls, K and Schroeder, AJ and Courtot, M and Osumi-Sutherland, D and Parkinson, H and Roncaglia, P and Lovering, RC and Foulger, RE and Huntley, RP and Denny, P and Campbell, NH and Kramarz, B and Patel, S and Buxton, JL and Umrao, Z and Deng, AT and Alrohaif, H and Mitchell, K and Ratnaraj, F and Omer, W and Rodriguez-Lopez, M and Chibucos, MC and Giglio, M and Nadendla, S and Duesbury, MJ and Koch, M and Meldal, BHM and Melidoni, A and Porras, P and Orchard, S and Shrivastava, A and Chang, HY and Finn, RD and Fraser, M and Mitchell, AL and Nuka, G and Potter, S and Rawlings, ND and Richardson, L and Sangrador-Vegas, A and Young, SY and Blake, JA and Christie, KR and Dolan, ME and Drabkin, HJ and Hill, DP and Ni, L and Sitnikov, D and Harris, MA and Hayles, J and Oliver, SG and Rutherford, K and Wood, V and Bahler, J and Lock, A and De Pons, J and Dwinell, M and Shimoyama, M and Laulederkind, S and Hayman, GT and Tutaj, M and Wang, SJ and D'Eustachio, P and Matthews, L and Balhoff, JP and Balakrishnan, R and Binkley, G and Cherry, JM and Costanzo, MC and Engel, SR and Miyasato, SR and ... and Gene Ontology Consortium and The Gene Ontology Consortium
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 01/2017, Volume 45, Issue D1, pp. D331 - D338
The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used... 
COMPLEX | DATABASE | ANNOTATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUEST | Computational Biology - methods | Molecular Sequence Annotation | Databases, Genetic | Phylogeny | Genomics - methods | Gene Ontology | Web Browser | Database Issue
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 44, p. 17802
  Antibodies that modulate receptor function have great untapped potential in the control of stem cell differentiation. In contrast to many natural ligands,... 
Proteins | Molecules | Signal transduction | Stem cells | Gene expression
Journal Article
by Jiang, Yuxiang and Oron, Ronnen Tal and Clark, T Wyatt and Bankapur, R Asma and D’Andrea, Daniel and Lepore, Rosalba and Funk, S Christopher and Kahanda, Indika and Verspoor, M Karin and Ben-Hur, Asa and Koo, Emily Da Chen and Penfold-Brown, Duncan and Shasha, Dennis and Youngs, Noah and Bonneau, Richard and Lin, Alexandra and Sahraeian, E Sayed M and Martelli, Luigi Pier and Profiti, Giuseppe and Casadio, Rita and Cao, Renzhi and Zhong, Zhaolong and Cheng, Jianlin and Altenhoff, Adrian and Skunca, Nives and Dessimoz, Christophe and Dogan, Tunca and Hakala, Kai and Kaewphan, Suwisa and Mehryary, Farrokh and Salakoski, Tapio and Ginter, Filip and Fang, Hai and Smithers, Ben and Oates, Matt and Gough, Julian and Törönen, Petri and Koskinen, Patrik and Holm, Liisa and Chen, Ching-Tai and Hsu, Wen-Lian and Bryson, Kevin and Cozzetto, Domenico and Minneci, Federico and Jones, T David and Chapman, Samuel and BKC, Dukka and Khan, K Ishita and Kihara, Daisuke and Ofer, Dan and Rappoport, Nadav and Stern, Amos and Cibrian-Uhalte, Elena and Denny, Paul and Foulger, E Rebecca and Hieta, Reija and Legge, Duncan and Lovering, C Ruth and Magrane, Michele and Melidoni, N Anna and Mutowo-Meullenet, Prudence and Pichler, Klemens and Shypitsyna, Aleksandra and Li, Biao and Zakeri, Pooya and ElShal, Sarah and Tranchevent, Léon-Charles and Das, Sayoni and Dawson, L Natalie and Lee, David and Lees, G Jonathan and Sillitoe, Ian and Bhat, Prajwal and Nepusz, Tamás and Romero, E Alfonso and Sasidharan, Rajkumar and Yang, Haixuan and Paccanaro, Alberto and Gillis, Jesse and Sedeño-Cortés, E Adriana and Pavlidis, Paul and Feng, Shou and Cejuela, M Juan and Goldberg, Tatyana and Hamp, Tobias and Richter, Lothar and Salamov, Asaf and Gabaldon, Toni and Marcet-Houben, Marina and Supek, Fran and Gong, Qingtian and Ning, Wei and Zhou, Yuanpeng and Tian, Weidong and Falda, Marco and Fontana, Paolo and Lavezzo, Enrico and Toppo, Stefano and Ferrari, Carlo and Giollo, Manuel and ...
ISSN 1474-7596, 2016
Background: A major bottleneck in our understanding of the molecular underpinnings of life is the assignment of function to proteins. While molecular... 
disease gene prioritization | protein function prediction
Journal Article
Nature communications, ISSN 2041-1723, 03/2019, Volume 10, Issue 1, pp. 1098 - 2
In the original HTML version of this Article, the order of authors within the author list was incorrect. The IMEx Consortium contributing authors were... 
Consortia | HyperText Markup Language | Mutation | Error correction | Molecular interactions
Journal Article
Atherosclerosis, ISSN 0021-9150, 2014, Volume 237, Issue 2, pp. e10 - e10
Journal Article
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), ISSN 0302-9743, 2017, Volume 10577, pp. 104 - 108
Conference Proceeding
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2006, Volume 320, pp. 329 - 341
Methods are described for the injection of mouse embryonic stem cells, in which Fmo genes have been targeted to disrupt gene function, into 3.5-d-old... 
Guidelines as Topic | Microinjections | Mice, Inbred C57BL | Male | Stem Cells - cytology | Mice, Knockout | Pregnancy | Animals | Stem Cells - enzymology | Embryo, Mammalian - cytology | Female | Embryo, Mammalian - enzymology | Mice | Oxygenases - genetics | Oxygenases - physiology
Journal Article