X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (43) 43
metallurgy (41) 41
organic chemistry (39) 39
biochemistry (28) 28
combinatorial chemistry (26) 26
beer (25) 25
compositions thereof (25) 25
culture media (25) 25
enzymology (25) 25
microbiology (25) 25
microorganisms or enzymes (25) 25
mutation or genetic engineering (25) 25
propagating, preserving or maintaining microorganisms (25) 25
spirits (25) 25
vinegar (25) 25
wine (25) 25
compositions or test papers therefor (22) 22
condition-responsive control in microbiological orenzymological processes (22) 22
measuring or testing processes involving enzymes, nucleicacids or microorganisms (22) 22
nucleic acids (22) 22
processes of preparing such compositions (22) 22
derivatives thereof (21) 21
investigating or analysing materials by determining theirchemical or physical properties (21) 21
libraries, e.g. chemical libraries, in silicolibraries (21) 21
measuring (21) 21
nucleosides (21) 21
nucleotides (21) 21
physics (21) 21
sugars (21) 21
testing (21) 21
peptides (18) 18
humans (15) 15
human necessities (11) 11
hygiene (11) 11
index medicus (11) 11
medical or veterinary science (11) 11
preparations for medical, dental, or toilet purposes (11) 11
specific therapeutic activity of chemical compounds ormedicinal preparations (11) 11
animals (10) 10
protein binding (8) 8
proteins (8) 8
biochemistry & molecular biology (6) 6
chemistry, multidisciplinary (6) 6
drug discovery (6) 6
chemistry, medicinal (5) 5
discovery (5) 5
dna - chemistry (5) 5
gene library (5) 5
molecular structure (5) 5
proteases (5) 5
selection (5) 5
structure-activity relationship (5) 5
base sequence (4) 4
chemistry, organic (4) 4
design (4) 4
dna - genetics (4) 4
drug design (4) 4
libraries (4) 4
mice (4) 4
oligonucleotides (4) 4
peptide library (4) 4
amino acid sequence (3) 3
antibodies (3) 3
biotechnology & applied microbiology (3) 3
cloning, molecular (3) 3
deoxyribonucleic acid--dna (3) 3
display (3) 3
dna (3) 3
dna primers (3) 3
fragments (3) 3
molecular biology (3) 3
molecular sequence data (3) 3
mutation (3) 3
nmr (3) 3
phage display (3) 3
pharmacology & pharmacy (3) 3
protease (3) 3
protease inhibitors - chemistry (3) 3
protein structure, tertiary (3) 3
templated organic-synthesis (3) 3
transcription factors (3) 3
trypsin (3) 3
activation (2) 2
affinity (2) 2
affinity maturation (2) 2
antibody fragments (2) 2
antineoplastic agents - chemistry (2) 2
apoptosis (2) 2
article (2) 2
binding (2) 2
biochemical research methods (2) 2
calmodulin (2) 2
calmodulin - chemistry (2) 2
caspases - metabolism (2) 2
cell line, tumor (2) 2
chromatography, affinity (2) 2
compound libraries (2) 2
dna-templated chemistry (2) 2
dose-response relationship, drug (2) 2
encoded self-assembling chemical libraries (2) 2
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (69) 69
French (10) 10
Spanish (8) 8
German (7) 7
Chinese (2) 2
Danish (1) 1
Korean (1) 1
Portuguese (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Biotechnology, ISSN 1087-0156, 05/2004, Volume 22, Issue 5, pp. 568 - 574
The isolation of molecules capable of high-affinity and specific binding to biological targets is a central problem in chemistry, biology and pharmaceutical... 
CARBONIC-ANHYDRASE | NMR | HIGH-AFFINITY LIGANDS | SPECIFICITY | COMBINATORIAL CHEMISTRY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DRUG DISCOVERY | PHAGE ANTIBODIES | BINDING-AFFINITY | INHIBITORS | PROTEINS | Oligonucleotides - metabolism | Animals | Albumins - metabolism | Cattle | Base Sequence | Humans | Protein Binding | DNA Primers | Carbonic Anhydrases - metabolism
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, p. 8777
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 05/2012, Volume 419, Issue 1-2, pp. 4 - 21
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2018, Volume 28, Issue 12, pp. 2153 - 2158
Journal Article
Blood, ISSN 0006-4971, 2019, Volume 133, Issue 13, pp. 1507 - 1516
A large unmet medical need exists for safer antithrombotic drugs because all currently approved anticoagulant agents interfere with hemostasis, leading to an... 
REDUCED INCIDENCE | THROMBOSIS | PATHWAY | RISK | COAGULATION | FACTOR-XI DEFICIENCY | HEMATOLOGY
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2007, Volume 46, Issue 25, pp. 4671 - 4674
Journal Article
Journal Article
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 03/2006, Volume 17, Issue 2, pp. 366 - 370
DNA-encoded libraries of small organic molecules facilitate the construction of large, encoded self-assembling chemical libraries for the identification of... 
Streptavidin - chemistry | DNA - chemistry | Animals | Gene Library | Streptavidin - metabolism | Humans | Protein Binding | Molecular Structure
Journal Article
Drug Discovery Today, ISSN 1359-6446, 2007, Volume 12, Issue 11, pp. 465 - 471
The isolation of specific binding molecules is a central problem in the drug discovery process and might be useful for the elucidation of the biological... 
ANTIBODIES | DISPLAY | FRAGMENTS | RECOGNITION | PROTEIN EVOLUTION | SEQUENCE | IN-VITRO SELECTION | PHARMACOLOGY & PHARMACY | DYNAMIC COMBINATORIAL CHEMISTRY | TEMPLATED ORGANIC-SYNTHESIS | OLIGONUCLEOTIDES | DNA - genetics | Animals | Peptide Library | Gene Library | Humans | Drug Design
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 10/2010, Volume 21, Issue 10, p. 1836
Collections of chemical compounds, individually attached to unique DNA fragments serving as amplifiable identification bar codes, are generally referred to as... 
Proteins | Inhibitor drugs | Molecular structure | Chemical synthesis | Gene expression | Chemical compounds | Deoxyribonucleic acid--DNA
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 08/2014, Volume 5, Issue 8, pp. 937 - 941
The cysteine protease adenain is the essential protease of adenovirus and, as such, represents a promising target for the treatment of ocular and other... 
inhibitor X-ray cocrystal structure | Adenoviral protease | adenoviral infection | structure-based design | CELLS | CHEMISTRY, MEDICINAL | ASSAYS | PROTEASE | ADENOVIRUS PROTEINASE
Journal Article