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animals; antibodies, monoclonal; antineoplastic agents; cetuximab; colorectal neoplasms; dna copy number variations; drug resistance, neoplasm; exome; female; genome, human; humans; insulin receptor substrate proteins; map kinase kinase 1; mice; molecular targeted therapy; mutation; proto-oncogene proteins p21; receptor, epidermal growth factor; receptor, erbb-2; receptor, fibroblast growth factor, type 1; receptor, platelet-derived growth factor alpha; xenograft model antitumor assays; genomics; multidisciplinary (1) 1
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Nature Genetics, ISSN 1061-4036, 04/2015, Volume 47, Issue 4, pp. 312 - 319
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 263 - 267
Colorectal cancer is the third most common cancer worldwide, with 1.2 million patients diagnosed annually. In late-stage colorectal cancer, the most commonly... 
PANITUMUMAB | THERAPY | MULTIDISCIPLINARY SCIENCES | SEQUENCE | ACQUIRED-RESISTANCE | SOMATIC MUTATION | IDENTIFICATION | GENE COPY NUMBER | ACTIVATING MUTATIONS | BREAST | INSIGHTS | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-2 - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Genomics | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Cetuximab - therapeutic use | Molecular Targeted Therapy | Receptor, Fibroblast Growth Factor, Type 1 - genetics | MAP Kinase Kinase 1 - genetics | Colorectal Neoplasms - drug therapy | Female | Antineoplastic Agents - pharmacology | Insulin Receptor Substrate Proteins - genetics | Colorectal Neoplasms - metabolism | Antibodies, Monoclonal - pharmacology | Cetuximab - pharmacology | DNA Copy Number Variations - genetics | Mutation - genetics | Genome, Human - genetics | Receptor, Epidermal Growth Factor - chemistry | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Exome - genetics | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Colorectal cancer | Drug metabolism | Genetic aspects | Identification and classification | Health aspects | Proteins | Epidermal growth factor | Genes | Clinical trials | Mutation | Kinases | Cancer therapies | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
Annals of Surgery, ISSN 0003-4932, 06/2013, Volume 257, Issue 6, pp. 1089 - 1095
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 4760 - 4760
Journal Article
Journal Article
European Journal of Surgical Oncology, ISSN 0748-7983, 2017, Volume 43, Issue 8, pp. 1472 - 1480
Journal Article