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1. Full Text Antiproteinuric effect of oral paricalcitol in chronic kidney disease
by Agarwal, Rajiv and Acharya, Muralidhar and Tian, J.I.N and Hippensteel, Richard L and Melnick, Joel Z and Qiu, Ping and Williams, Laura and Batlle, Daniel
Kidney international, ISSN 0085-2538, 12/2005, Volume 68, Issue 6, pp. 2823 - 2828
chronic kidney disease | paricalcitol | proteinuria | vitamin D | Chronic kidney disease | Vitamin D | Paricalcitol | Proteinuria | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Urinary tract. Prostate gland | Nephrology. Urinary tract diseases | Biological and medical sciences | Kidneys | Medical sciences | Urinary system involvement in other diseases. Miscellaneous | Hyperparathyroidism, Secondary - metabolism | Hyperparathyroidism, Secondary - drug therapy | Administration, Oral | Humans | Middle Aged | Male | Treatment Outcome | Renal Insufficiency, Chronic - complications | Renal Insufficiency, Chronic - drug therapy | Proteinuria - drug therapy | Parathyroid Hormone - metabolism | Ergocalciferols - administration & dosage | Female | Aged | Hyperparathyroidism, Secondary - etiology | Proteinuria - complications | Index Medicus
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2. Full Text Mo1245 - Effect of Creon Therapy on Exocrine Pancreatic Insufficiency Symptoms and Coefficient of Fat Absorption Associated with Chronic Pancreatitis
by Barkin, Jodie A and Hall, Jerry A and Liao, Qiming and Melnick, Joel Z and Barkin, Jamie S
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-719 - S-719
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3. Full Text Modified-Release Calcifediol Effectively Controls Secondary Hyperparathyroidism Associated with Vitamin D Insufficiency in Chronic Kidney Disease
by Sprague, Stuart M and Silva, Arnold L and Al-Saghir, Fahd and Damle, Radhika and Tabash, Samir P and Petkovich, Martin and Messner, Eric J and White, Jay A and Melnick, Joel Z and Bishop, Charles W
American journal of nephrology, ISSN 0250-8095, 02/2015, Volume 40, Issue 6, pp. 535 - 545
Original Report: Patient-Oriented, Translational Research | Parathyroid hormone (PTH) | Vitamin D | Calcifediol (25-hydroxyvitamin D | ) | Secondary hyperparathyroidism (SHPT) | Vitamin D insufficiency | Calcitriol (1,25-dihydroxyvitamin D | Chronic kidney disease (CKD) | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Calcifediol - administration & dosage | Calcifediol - blood | Double-Blind Method | Hyperparathyroidism, Secondary - drug therapy | Humans | Middle Aged | Vitamin D Deficiency - drug therapy | Male | Parathyroid Hormone - blood | Renal Insufficiency, Chronic - complications | Vitamin D - blood | Renal Insufficiency, Chronic - blood | Hyperparathyroidism, Secondary - blood | Vitamin D Deficiency - blood | Adult | Female | Vitamin D - analogs & derivatives | Aged | Vitamins - blood | Hyperparathyroidism, Secondary - etiology | Vitamin D Deficiency - etiology | Delayed-Action Preparations | Vitamins - administration & dosage | Chronic kidney failure | Parathyroid hormone | Mortality | Cytochrome P-450 | Calcifediol | Alfacalcidol | Health aspects | Hyperparathyroidism | Index Medicus
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4. Full Text Use of Extended-Release Calcifediol to Treat Secondary Hyperparathyroidism in Stages 3 and 4 Chronic Kidney Disease
by Sprague, Stuart M and Crawford, Paul W and Melnick, Joel Z and Strugnell, Stephen A and Ali, Shaukat and Mangoo-Karim, Roberto and Lee, Sungchun and Petkovich, P. Martin and Bishop, Charles W
American journal of nephrology, ISSN 0250-8095, 10/2016, Volume 44, Issue 4, pp. 316 - 325
Original Report: Patient-Oriented, Translational Research | Chronic kidney disease | Calcifediol (25-hydroxyvitamin D3) | Vitamin D | Vitamin D insufficiency | Parathyroid hormone | Secondary hyperparathyroidism | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Humans | Middle Aged | Vitamin D Deficiency - drug therapy | Male | Parathyroid Hormone - blood | Renal Insufficiency, Chronic - complications | Calcium - blood | Calcifediol - adverse effects | Vitamin D Deficiency - blood | Hyperparathyroidism - blood | Hyperparathyroidism - drug therapy | Female | Vitamin D Deficiency - etiology | Hyperparathyroidism - etiology | Glomerular Filtration Rate | Double-Blind Method | Calcifediol - therapeutic use | Calcium - urine | Vitamins - therapeutic use | Creatinine - urine | Renal Insufficiency, Chronic - physiopathology | Vitamin D - blood | Vitamins - adverse effects | Fibroblast Growth Factors - blood | Phosphorus - blood | Delayed-Action Preparations - therapeutic use | Vitamin D - analogs & derivatives | Aged | 24,25-Dihydroxyvitamin D 3 - blood | Drugs | Chronic kidney failure | Controlled release preparations | Calcifediol | Dosage and administration | Alfacalcidol | Drug therapy | Hyperparathyroidism | Controlled release | Index Medicus
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5. Full Text Oral Paricalcitol for the Treatment of Secondary Hyperparathyroidism in Patients on Hemodialysis or Peritoneal Dialysis
by Ross, Edward A and Tian, Jin and Abboud, Hanna and Hippensteel, Richard and Melnick, Joel Z and Pradhan, Rajendra S and Williams, Laura A and Hamm, L. Lee and Sprague, Stuart M
American journal of nephrology, ISSN 0250-8095, 11/2007, Volume 28, Issue 1, pp. 97 - 106
Original Report: Patient-Oriented, Translational Research | Chronic renal failure | Chronic renal insufficiency | Secondary hyperparathyroidism | Paricalcitol | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Hyperparathyroidism, Secondary - drug therapy | Administration, Oral | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Treatment Outcome | Parathyroid Hormone - blood | Receptors, Calcitriol - metabolism | Kidney Failure, Chronic - therapy | Calcium - blood | Hyperparathyroidism, Secondary - blood | Ergocalciferols - adverse effects | Peritoneal Dialysis | Phosphorus - blood | Kidney Failure, Chronic - complications | Aged, 80 and over | Placebos | Adult | Ergocalciferols - administration & dosage | Female | Aged | Hyperparathyroidism, Secondary - etiology | Renal Dialysis | Index Medicus
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6. Full Text A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria
by Macintyre, Fiona and Adoke, Yeka and Tiono, Alfred B and Duong, Tran Thanh and Mombo-Ngoma, Ghyslain and Bouyou-Akotet, Marielle and Tinto, Halidou and Bassat, Quique and Issifou, Saadou and Adamy, Marc and Demarest, Helen and Duparc, Stephan and Leroy, Didier and Laurijssens, Bart E and Biguenet, Sophie and Kibuuka, Afizi and Tshefu, Antoinette Kitoto and Smith, Melnick and Foster, Chanelle and Leipoldt, Illse and Kremsner, Peter G and Phuc, Bui Quang and Ouedraogo, Alphonse and Ramharter, Michael and Hong, Nguyen Van and Mbouoronde, Christelle Offouga and Kinko, Joy Luzingu and Losoma, Joseph Atibu and Manego, Rella Zoleko and Groger, Mirjam and Klicpera, Anna and Mischlinger, Johannes and Barry, Aissata and Ouattara, San Maurice and Coulibaly, Sam and Moïse, Kabore and Sombié, Olivier and Bognini, Joel Dofinissery and Sitoe, Antonio and Matambisso, Gloria and Gaaloul, Myriam El and Gobeau, Nathalie and Varo, Rosauro and Mayor, Alfredo and Cox, Eugene H and Maringwa, John T and OZ-Piperaquine Study Grp and OZ-Piperaquine Study Group and on behalf of the OZ-Piperaquine Study Group
BMC medicine, ISSN 1741-7015, 10/2017, Volume 15, Issue 1, pp. 181 - 181
Single dose combination treatment | Artefenomel | Piperaquine | Uncomplicated Plasmodium falciparum malaria | Modelling and simulation | Dose-response | Phase II B | Children | Pharmacokinetics | OZ439 | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Malaria, Falciparum - drug therapy | Double-Blind Method | Humans | Middle Aged | Africa | Artemisinins - administration & dosage | Child, Preschool | Infant | Male | Treatment Outcome | Antimalarials - therapeutic use | Quinolines - administration & dosage | Dose-Response Relationship, Drug | Young Adult | Asian Continental Ancestry Group | Antimalarials - administration & dosage | Plasmodium falciparum - genetics | Adolescent | Adult | Female | Quinolines - therapeutic use | Drug Therapy, Combination | Child | Plasmodium falciparum | Complications and side effects | Usage | Care and treatment | Malaria | Antimalarials | Dosage and administration | Research | Simulation methods | Vector-borne diseases | Mortality | Erythrocytes | Clinical trials | Objectives | Infections | Pharmacology | Parasites | Patients | Evidence-based medicine | Genotype & phenotype | Adults | Drug dosages | Index Medicus | Malària | Dose–response
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7. Full Text Paricalcitol-treated patients experience improved hospitalization outcomes compared with calcitriol-treated patients in real-world clinical settings
by Dobrez, Deborah G and Mathes, Angelo and Amdahl, Michael and Marx, Steven E and Melnick, Joel Z and Sprague, Stuart M
Nephrology, dialysis, transplantation, ISSN 0931-0509, 05/2004, Volume 19, Issue 5, pp. 1174 - 1181
Costs | Vitamin D | Hospitalizations | Haemodialysis | Multivariate | Hyperparathyroidism | Outcomes | Transplantation | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Glomerulonephritis | Emergency and intensive care: renal failure. Dialysis management | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Nephropathies. Renovascular diseases. Renal failure | Transfusions. Complications. Transfusion reactions. Cell and gene therapy | Nephrology. Urinary tract diseases | Biological and medical sciences | Intensive care medicine | Medical sciences | Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis | Hyperparathyroidism, Secondary - drug therapy | Risk Assessment | Humans | Kidney Failure, Chronic - complications | Medical Records | Hospitalization - statistics & numerical data | Ergocalciferols - therapeutic use | Treatment Outcome | Retrospective Studies | Calcitriol - therapeutic use | Hyperparathyroidism, Secondary - etiology | Renal Dialysis | Index Medicus
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8. Full Text Intravenous Paricalcitol for Treatment of Secondary Hyperparathyroidism in Children on Hemodialysis
by Greenbaum, Larry A., MD, PhD and Benador, Nadine, MD and Goldstein, Stuart L., MD and Paredes, Ana, MD and Melnick, Joel Z., MD and Mattingly, Susan, BSN and Amdahl, Michael, MS and Williams, Laura A., MD, MPH and Salusky, Isidro B., MD
American journal of kidney diseases, ISSN 0272-6386, 2007, Volume 49, Issue 6, pp. 814 - 823
Nephrology | hemodialysis | secondary hyperparathyroidism | end-stage renal disease | children | Paricalcitol | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Non tumoral diseases. Target tissue resistance. Benign neoplasms | Nephropathies. Renovascular diseases. Renal failure | Renal failure | Nephrology. Urinary tract diseases | Biological and medical sciences | Endocrinopathies | Medical sciences | Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) | Hyperparathyroidism - etiology | Double-Blind Method | Humans | Bone Density Conservation Agents - therapeutic use | Child, Preschool | Ergocalciferols - therapeutic use | Male | Bone Density Conservation Agents - administration & dosage | Parathyroid Hormone - blood | Kidney Failure, Chronic - therapy | Calcium - blood | Kidney Failure, Chronic - blood | Phosphorus - blood | Adolescent | Kidney Failure, Chronic - complications | Hyperparathyroidism - blood | Hyperparathyroidism - drug therapy | Adult | Ergocalciferols - administration & dosage | Female | Infusions, Intravenous | Child | Renal Dialysis | Index Medicus
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9. Full Text 117: Open Label, Placebo-Controlled, Randomized, Single Dose Escalation and Repeat Dose Study of Intravenous CTA018 in Healthy Volunteers
by Karjalainen, Jukka and Warren, Jeffery and Melnick, Joel Z and Willmer, Jonathan
American journal of kidney diseases, ISSN 0272-6386, 2008, Volume 51, Issue 4, pp. B57 - B57
Nephrology
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10. Full Text Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysis
by Greenbaum, Larry A and Grenda, Ryszard and Qiu, Ping and Restaino, Irene and Wojtak, Amy and Paredes, Ana and Benador, Nadine and Melnick, Joel Z and Williams, Laura A and Salusky, Isidro B
Pediatric nephrology (Berlin, West), ISSN 0931-041X, 5/2005, Volume 20, Issue 5, pp. 622 - 630
Phosphorus | Renal osteodystrophy | Calcium | End stage renal disease | Secondary hyperparathyroidism | Pediatrics | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Injections, Intravenous | Hyperparathyroidism, Secondary - drug therapy | Calcium Compounds | Humans | Calcitriol - adverse effects | Child, Preschool | Male | Parathyroid Hormone - blood | Chronic Kidney Disease-Mineral and Bone Disorder - drug therapy | Kidney Failure, Chronic - therapy | Calcitriol - administration & dosage | Calcium - blood | Calcium Channel Agonists - administration & dosage | Acetates - administration & dosage | Adolescent | Kidney Failure, Chronic - complications | Phosphates - blood | Female | Calcium Carbonate - administration & dosage | Calcium Channel Agonists - adverse effects | Chronic Kidney Disease-Mineral and Bone Disorder - etiology | Hyperparathyroidism, Secondary - etiology | Child | Renal Dialysis | Index Medicus
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11. Full Text A Comparison of Dosing Regimens of Paricalcitol Capsule for the Treatment of Secondary Hyperparathyroidism in CKD Stages 3 and 4
by Abboud, Hanna and Coyne, Daniel and Smolenski, Olgierd and Anger, Michael and Lunde, Norman and Qiu, Ping and Hippensteel, Rich and Pradhan, Rajendra S and Palaparthy, Rameshraja V and Kavanaugh, Anne and Melnick, Joel Z and Williams, Laura A and Batlle, Daniel
American journal of nephrology, ISSN 0250-8095, 04/2006, Volume 26, Issue 1, pp. 105 - 114
Original Report: Laboratory Investigation | Hypercalcemia | Once-daily dosing, paricalcitol | Vitamin D | Intermittent dosing, paricalcitol | Hyperphosphatemia | Pulse dosing, paricalcitol | Vitamin D receptor activator | Nephrology. Urinary tract diseases | Biological and medical sciences | Endocrinopathies | Non tumoral diseases. Target tissue resistance. Benign neoplasms | Medical sciences | Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) | Prospective Studies | Double-Blind Method | Drug Administration Schedule | Hyperparathyroidism, Secondary - drug therapy | Humans | Middle Aged | Male | Parathyroid Hormone - blood | Vitamins - pharmacokinetics | Calcium - blood | Capsules | Phosphorus - blood | Ergocalciferols - pharmacokinetics | Aged, 80 and over | Adult | Ergocalciferols - administration & dosage | Female | Aged | Kidney Diseases - complications | Chronic Disease | Vitamins - administration & dosage | Index Medicus
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12. Full Text Contents Vol. 40, 2014
American journal of nephrology, ISSN 0250-8095, 02/2015, Volume 40, Issue 6, pp. I - VI
Further Section
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13. Full Text PARICALCITOL (A SELECTIVE VITAMIN D RECEPTOR ACTIVATOR) THERAPY FOR ICU-RELATED HYPOCALCEMIA IS ASSOCIATED WITH REDUCED INFECTIONS
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by Douglas, Ivor S and Kaufman, David C and Amdahl, Michael J and Orzel, Stacey A and Williams, Laura A and Melnick, Joel Z
Critical care medicine, ISSN 0090-3493, 12/2006, Volume 34, p. A78
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14. Full Text Adenosine triphosphate citrate lyase mediates hypocitraturia in rats
by Melnick, Joel Z and Srere, Paul A and Elshourbagy, Nabil A and Moe, Orson W and Preisig, Patricia A and Alpern, Robert J
The Journal of clinical investigation, ISSN 0021-9738, 11/1996, Volume 98, Issue 10, pp. 2381 - 2387
urolithiasis | hydroxycitrate | hypokalemia | citrate | acidosis | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | ATP Citrate (pro-S)-Lyase - antagonists & inhibitors | Kidney Cortex - metabolism | ATP Citrate (pro-S)-Lyase - immunology | ATP Citrate (pro-S)-Lyase - physiology | ATP Citrate (pro-S)-Lyase - genetics | Rats | Immunoblotting | Male | Food, Formulated | Rats, Sprague-Dawley | Acidosis, Renal Tubular - metabolism | RNA, Messenger - biosynthesis | Blotting, Northern | Citrates - pharmacology | Kidney - metabolism | Animals | Citrates - metabolism | Hypokalemia - metabolism | Urinary Calculi - metabolism | Index Medicus | Abridged Index Medicus
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