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1. Full Text Human symptoms-disease network
by Zhou, Xuezhong and Menche, Jörg and Barabási, Albert-László and Sharma, Amitabh
Nature communications, ISSN 2041-1723, 06/2014, Volume 5, Issue 1, pp. 4212 - 4212
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Models, Theoretical | Proteins - genetics | Systems Theory | Genetic Predisposition to Disease | Phenotype | Disease - genetics | Humans | Index Medicus
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2. Full Text Network-based in silico drug efficacy screening
by Guney, Emre and Menche, Jörg and Vidal, Marc and Barábasi, Albert-László
Nature communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10331 - 10331
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Index Medicus
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3. Full Text Network medicine: A new paradigm for cardiovascular disease research and beyond
by Menche, Jörg
Cardiovascular research, ISSN 0008-6363, 08/2017, Volume 113, Issue 10, pp. e29 - e30
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiovascular Diseases - metabolism | Signal Transduction | Humans | Cardiovascular Diseases - therapy | Biomedical Research - trends | Gene Regulatory Networks | Cardiovascular Diseases - genetics | Protein Interaction Maps | Systems Biology - methods | Systems Biology - trends | Diffusion of Innovation | Biomedical Research - methods | Cardiology - trends | Cardiology - methods | Cardiovascular Diseases - diagnosis | Index Medicus
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4. Full Text Uncovering disease-disease relationships through the incomplete interactome
by Jörg Menche and Amitabh Sharma and Maksim Kitsak and Susan Dina Ghiassian and Marc Vidal and Joseph Loscalzo and Albert-László Barabási
Science (American Association for the Advancement of Science), ISSN 0036-8075, 2/2015, Volume 347, Issue 6224, pp. 841 - 841
RESEARCH ARTICLE SUMMARY | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Disease | Molecular biology | Genes | Proteins | Networks | Maps | Similarity | Mathematical analysis | Modules | Disease control
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5. Full Text Environmental arginine controls multinuclear giant cell metabolism and formation
by Brunner, Julia S and Vulliard, Loan and Hofmann, Melanie and Kieler, Markus and Lercher, Alexander and Vogel, Andrea and Russier, Marion and Brueggenthies, Johanna B and Kerndl, Martina and Saferding, Victoria and Niederreiter, Birgit and Junza, Alexandra and Frauenstein, Annika and Scholtysek, Carina and Mikami, Yohei and Klavins, Kristaps and Kroenke, Gerhard and Bergthaler, Andreas and O'Shea, John J and Weichhart, Thomas and Meissner, Felix and Smolen, Josef S and Cheng, Paul and Yanes, Oscar and Menche, Joerg and Murray, Peter J and Sharif, Omar and Blueml, Stephan and Schabbauer, Gernot
Nature communications, ISSN 2041-1723, 01/2020, Volume 11, Issue 1, pp. 431 - 431
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Arthritis - physiopathology | RANK Ligand - metabolism | Arthritis - metabolism | Humans | Interleukin-4 - metabolism | Mice, Inbred C57BL | Giant Cells - cytology | Arthritis - genetics | Osteoclasts - cytology | Osteoclasts - metabolism | Mechanistic Target of Rapamycin Complex 1 - metabolism | Citric Acid Cycle | RANK Ligand - genetics | Mechanistic Target of Rapamycin Complex 1 - genetics | Animals | Giant Cells - immunology | Female | Mice | Bone Remodeling | Arginine - metabolism | Osteogenesis | Tricarboxylic acid cycle | Membrane fusion | Deprivation | Animal models | Translation | Transcription | Sarcoidosis | Bone remodelling | Pathogenesis | Amino acids | Arthritis | Metabolism | Diseases | Osteoclastogenesis | Schistosomiasis | Interleukin 4 | Biomedical materials | Depletion | Arginine | Metabolites | Giant cells | TRANCE protein | Index Medicus
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6. Full Text Mapping the perturbome network of cellular perturbations
by Caldera, Michael and Mueller, Felix and Kaltenbrunner, Isabel and Licciardello, Marco P and Lardeau, Charles-Hugues and Kubicek, Stefan and Menche, Joerg
Nature communications, ISSN 2041-1723, 11/2019, Volume 10, Issue 1, pp. 5140 - 14
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Drug Interactions | Models, Biological | Cell Shape | Humans | Cell Line, Tumor | Cells - metabolism | Protein Interaction Mapping | Drugs | Organic chemistry | Cellular communication | Medical treatment | Molecular interactions | Morphology | Cytology | Mapping | Mathematical morphology | Cell morphology | Index Medicus
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7. Full Text The immune system as a social network
by Bergthaler, Andreas and Menche, Jörg
Nature immunology, ISSN 1529-2908, 04/2017, Volume 18, Issue 5, pp. 481 - 482
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Communication | Immune System - immunology | Humans | Proteomics | Social Support | Cellular proteins | Genetic aspects | Properties | Immune system | Immunological research | Index Medicus
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8. Full Text Canonical genetic signatures of the adult human brain
by Hawrylycz, Michael and Miller, Jeremy A and Menon, Vilas and Feng, David and Dolbeare, Tim and Guillozet-Bongaarts, Angela L and Jegga, Anil G and Aronow, Bruce J and Lee, Chang-Kyu and Bernard, Amy and Glasser, Matthew F and Dierker, Donna L and Menche, Jörg and Szafer, Aaron and Collman, Forrest and Grange, Pascal and Berman, Kenneth A and Mihalas, Stefan and Yao, Zizhen and Stewart, Lance and Barabási, Albert-László and Schulkin, Jay and Phillips, John and Ng, Lydia and Dang, Chinh and R Haynor, David and Jones, Allan and Van Essen, David C and Koch, Christof and Lein, Ed
Nature neuroscience, ISSN 1097-6256, 11/2015, Volume 18, Issue 12, pp. 1832 - 1844
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Animals | Gene Regulatory Networks - genetics | Humans | Adult | Mice | Transcriptome - genetics | Brain - physiology | Nerve Net - physiology | Neural circuitry | Brain research | Brain mapping | Genetic research | Genetic aspects | Research | Gene expression | Methods | Index Medicus
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9. Full Text MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation
by Sdelci, Sara and Rendeiro, André F and Rathert, Philipp and You, Wanhui and Lin, Jung-Ming G and Ringler, Anna and Hofstätter, Gerald and Moll, Herwig P and Gürtl, Bettina and Farlik, Matthias and Schick, Sandra and Klepsch, Freya and Oldach, Matthew and Buphamalai, Pisanu and Schischlik, Fiorella and Májek, Peter and Parapatics, Katja and Schmidl, Christian and Schuster, Michael and Penz, Thomas and Buckley, Dennis L and Hudecz, Otto and Imre, Richard and Wang, Shuang-Yan and Maric, Hans Michael and Kralovics, Robert and Bennett, Keiryn L and Müller, Andre C and Mechtler, Karl and Menche, Jörg and Bradner, James E and Winter, Georg E and Klavins, Kristaps and Casanova, Emilio and Bock, Christoph and Zuber, Johannes and Kubicek, Stefan
Nature genetics, ISSN 1061-4036, 06/2019, Volume 51, Issue 6, pp. 990 - 998
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Loss of Function Mutation | Signal Transduction | Humans | Gene Expression Regulation | Nuclear Proteins - metabolism | Gene Knockout Techniques | Protein Interaction Mapping | Protein Interaction Maps | Protein Transport | Transcription Factors - metabolism | Minor Histocompatibility Antigens - metabolism | Cell Nucleus - metabolism | Cell Line, Tumor | Folic Acid - metabolism | Protein Binding | Transcription, Genetic | Chromatin - genetics | Cell Cycle Proteins | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Enzymes | Control | Composition | Synthesis | Metabolites | Analysis | Genetic transcription | Genetic regulation | Chromatin | Transcription factors | Dehydrogenases | Transcription | Peptides | Leukemia | Gene regulation | DNA damage | Genomics | Cell viability | Biosynthesis | Genomes | Synergism | Folic acid | Genetic screening | Methylenetetrahydrofolate dehydrogenase | Proteins | Vitamin B | Deoxyribonucleic acid--DNA | Cloning | Pharmacology | Metabolism | Gene expression | Chemical compounds | Screens | Epigenetics | Gene loci | Mutation | Cancer | Pharmaceuticals | Index Medicus
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10. Full Text Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
by Lercher, Alexander and Bhattacharya, Anannya and Popa, Alexandra M and Caldera, Michael and Schlapansky, Moritz F and Baazim, Hatoon and Agerer, Benedikt and Gürtl, Bettina and Kosack, Lindsay and Májek, Peter and Brunner, Julia S and Vitko, Dijana and Pinter, Theresa and Genger, Jakob-Wendelin and Orlova, Anna and Pikor, Natalia and Reil, Daniela and Ozsvár-Kozma, Maria and Kalinke, Ulrich and Ludewig, Burkhard and Moriggl, Richard and Bennett, Keiryn L and Menche, Jörg and Cheng, Paul N and Schabbauer, Gernot and Trauner, Michael and Klavins, Kristaps and Bergthaler, Andreas
Immunity (Cambridge, Mass.), ISSN 1074-7613, 12/2019, Volume 51, Issue 6, pp. 1074 - 1087.e9
infection | interferons | hepatocyte | inflammation | immunometabolism | liver | urea cycle | hepatitis | virus | CD8 T cells | Life Sciences & Biomedicine | Immunology | Science & Technology | Liver - virology | Lymphocytic choriomeningitis virus - immunology | Ornithine - blood | Male | Hepatocytes - metabolism | Ornithine Carbamoyltransferase - genetics | Interferon Type I - immunology | Lymphocytic Choriomeningitis - immunology | CD4-Positive T-Lymphocytes - immunology | Signal Transduction - immunology | Liver - immunology | Female | Urea - metabolism | Vero Cells | Receptor, Interferon alpha-beta - metabolism | Cell Line | Cricetinae | Chlorocebus aethiops | Liver - metabolism | Mice, Inbred C57BL | Mice, Knockout | Animals | Arginine - blood | Mice | CD8-Positive T-Lymphocytes - immunology | Metabolomics | Transcription | CD8 antigen | Liver | Chronic infection | Homeostasis | Viruses | Amino acids | Lipids | Infections | Lymphocytes T | Gene sequencing | Proteins | Hepatitis | Arginine | Metabolites | Lymphocytes | Ureas | Food | Pathogens | RNA viruses | Cytokines | Immunoregulation | Cloning | Inflammation | Ribonucleic acid--RNA | Metabolism | Gene expression | Urea | Hepatocytes | Proteomics | Interferon | Ornithine | Viral infections | Index Medicus
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