X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (15) 15
index medicus (15) 15
cancer (8) 8
neoplasms - genetics (8) 8
neoplasms - drug therapy (7) 7
antineoplastic agents - therapeutic use (6) 6
article (6) 6
cell line, tumor (6) 6
genomes (6) 6
genomics (6) 6
bioinformatics (5) 5
biotechnology & applied microbiology (5) 5
cell lines (5) 5
computer simulation (5) 5
machine learning (5) 5
models, genetic (5) 5
biochemistry & molecular biology (4) 4
databases, factual (4) 4
dose-response relationship, drug (4) 4
drug resistance, neoplasm - genetics (4) 4
ecology (4) 4
genetic aspects (4) 4
genomics - methods (4) 4
identification (4) 4
life sciences (4) 4
multidisciplinary sciences (4) 4
mutation (4) 4
research (4) 4
resource (4) 4
studies (4) 4
systems biology (4) 4
analysis of variance (3) 3
animals (3) 3
antineoplastic agents - pharmacology (3) 3
biology (3) 3
cell biology (3) 3
computational biology - methods (3) 3
curriculum development (3) 3
drug therapy (3) 3
drug-sensitivity (3) 3
drugs (3) 3
educational leadership (3) 3
expression (3) 3
gene expression (3) 3
genetics, population (3) 3
health aspects (3) 3
incidence (3) 3
inhibition (3) 3
mutations (3) 3
pharmacogenetics (3) 3
pharmacogenetics - methods (3) 3
pharmacology (3) 3
phenotype (3) 3
phytoplankton (3) 3
predictions (3) 3
quantitative methods (3) 3
religious education (3) 3
resistance (3) 3
school administration (3) 3
sensitivity (3) 3
software (3) 3
tumor cell lines (3) 3
tumors (3) 3
algae (2) 2
algorithms (2) 2
analysis (2) 2
antineoplastic agents (2) 2
biochemical research methods (2) 2
biomarkers (2) 2
biotechnology (2) 2
birth-weight infants (2) 2
bloom (2) 2
carcinogenesis (2) 2
cells (2) 2
chemotherapy (2) 2
computation (2) 2
computer applications (2) 2
computer science (2) 2
crowdsourcing (2) 2
càncer (2) 2
data bases (2) 2
discovery (2) 2
dna methylation (2) 2
drug discovery (2) 2
drug discovery - methods (2) 2
drug resistance (2) 2
encyclopedia (2) 2
environmental aspects (2) 2
epigenetic inheritance (2) 2
eukaryotes (2) 2
farmacogenètica (2) 2
female (2) 2
fenotip (2) 2
gene dosage (2) 2
gene expression profiling (2) 2
gene-expression signatures (2) 2
genetic predisposition to disease (2) 2
genetic predisposition to disease - genetics (2) 2
genetic research (2) 2
genetic transcription (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3886 - 3886
Journal Article
Cell, ISSN 0092-8674, 07/2016, Volume 166, Issue 3, pp. 740 - 754
Journal Article
by Costello, James C and Heiser, Laura M and Georgii, Elisabeth and Gönen, Mehmet and Menden, Michael P and Wang, Nicholas J and Bansal, Mukesh and Ammad-Ud-Din, Muhammad and Hintsanen, Petteri and Khan, Suleiman A and Mpindi, John-Patrick and Kallioniemi, Olli and Honkela, Antti and Aittokallio, Tero and Wennerberg, Krister and Collins, James J and Gallahan, Dan and Singer, Dinah and Saez-Rodriguez, Julio and Kaski, Samuel and Gray, Joe W and Stolovitzky, Gustavo and Abbuehl, Jean-Paul and Allen, Jeffrey and Altman, Russ B and Balcome, Shawn and Battle, Alexis and Bender, Andreas and Berger, Bonnie and Bernard, Jonathan and Bhattacharjee, Madhuchhanda and Bhuvaneshwar, Krithika and Bieberich, Andrew A and Boehm, Fred and Califano, Andrea and Chan, Christina and Chen, Beibei and Chen, Ting-Huei and Choi, Jaejoon and Coelho, Luis Pedro and Cokelaer, Thomas and Collins, James C and Creighton, Chad J and Cui, Jike and Dampier, Will and Davisson, V. Jo and De Baets, Bernard and Deshpande, Raamesh and DiCamillo, Barbara and Dundar, Murat and Duren, Zhana and Ertel, Adam and Fan, Haoyang and Fang, Hongbin and Gauba, Robinder and Gottlieb, Assaf and Grau, Michael and Gusev, Yuriy and Ha, Min Jin and Han, Leng and Harris, Michael and Henderson, Nicholas and Hejase, Hussein A and Homicsko, Krisztian and Hou, Jack P and Hwang, Woochang and IJzerman, Adriaan P and Karacali, Bilge and Keles, Sunduz and Kendziorski, Christina and Kim, Junho and Kim, Min and Kim, Youngchul and Knowles, David A and Koller, Daphne and Lee, Junehawk and Lee, Jae K and Lenselink, Eelke B and Li, Biao and Li, Bin and Li, Jun and Liang, Han and Ma, Jian and Madhavan, Subha and Mooney, Sean and Myers, Chad L and Newton, Michael A and Overington, John P and Pal, Ranadip and Peng, Jian and Pestell, Richard and Prill, Robert J and Qiu, Peng and Rajwa, Bartek and Sadanandam, Anguraj and Sambo, Francesco and Shin, Hyunjin and Song, Jiuzhou and Song, Lei and Sridhar, Arvind and ... and NCI DREAM Community
Nature Biotechnology, ISSN 1087-0156, 12/2014, Volume 32, Issue 12, pp. 1202 - 1212
Journal Article
by Bansal, Mukesh and Yang, Jichen and Karan, Charles and Menden, Michael P and Costello, James C and Tang, Hao and Xiao, Guanghua and Li, Yajuan and Allen, Jeffrey and Zhong, Rui and Chen, Beibei and Kim, Minsoo and Wang, Tao and Heiser, Laura M and Realubit, Ronald and Mattioli, Michela and Alvarez, Mariano J and Shen, Yao and Gallahan, Daniel and Singer, Dinah and Saez-Rodriguez, Julio and Xie, Yang and Stolovitzky, Gustavo and Califano, Andrea and Abbuehl, Jean-Paul and Altman, Russ B and Balcome, Shawn and Bell, Ana and Bender, Andreas and Berger, Bonnie and Bernard, Jonathan and Bieberich, Andrew A and Borboudakis, Giorgos and Chan, Christina and Chen, Ting-Huei and Choi, Jaejoon and Coelho, Luis Pedro and Creighton, Chad J and Dampier, Will and Davisson, V. Jo and Deshpande, Raamesh and Diao, Lixia and Di Camillo, Barbara and Dundar, Murat and Ertel, Adam and Goswami, Chirayu P and Gottlieb, Assaf and Gould, Michael N and Goya, Jonathan and Grau, Michael and Gray, Joe W and Hejase, Hussein A and Hoffmann, Michael F and Homicsko, Krisztian and Homilius, Max and Hwang, Woochang and Ijzerman, Adriaan P and Kallioniemi, Olli and Karacali, Bilge and Kaski, Samuel and Kim, Junho and Krishnan, Arjun and Lee, Junehawk and Lee, Young-Suk and Lenselink, Eelke B and Lenz, Peter and Li, Lang and Li, Jun and Liang, Han and Mpindi, John-Patrick and Myers, Chad L and Newton, Michael A and Overington, John P and Parkkinen, Juuso and Prill, Robert J and Peng, Jian and Pestell, Richard and Qiu, Peng and Rajwa, Bartek and Sadanandam, Anguraj and Sambo, Francesco and Sridhar, Arvind and Sun, Wei and Toffolo, Gianna M and Tozeren, Aydin and Troyanskaya, Olga G and Tsamardinos, Ioannis and Van Vlijmen, Herman W. T and Wang, Wen and Wegner, Joerg K and Wennerberg, Krister and Van Westen, Gerard J. P and Xia, Tian and Yang, Yang and Yao, Victoria and Yuan, Yuan and Zeng, Haoyang and Zhang, Shihua and Zhao, Junfei and Zhou, Jian and NCI-DREAM Community and Cellworks Group
Nature Biotechnology, ISSN 1087-0156, 12/2014, Volume 32, Issue 12, pp. 1213 - 1222
Recent therapeutic successes have renewed interest in drug combinations, but experimental screening approaches are costly and often identify only small numbers... 
DRUG-COMBINATIONS | NETWORK | THERAPY | INHIBITION | MODELS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE | CANCER | EXPRESSION | CHEMOTHERAPY | SYSTEMS BIOLOGY | Drug Synergism | B-Lymphocytes - drug effects | Algorithms | Computer Simulation | Humans | Drug Combinations | Pharmaceutical research | Drug therapy, Combination | Research | Computers | Drug therapy | Predictions | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 12/2015, Volume 528, Issue 7580, pp. 84 - 87
Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here, we... 
Journal Article
Journal Article
Nature, ISSN 0028-0836, 12/2015, Volume 528, Issue 7580, pp. 84 - 87
Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we... 
DRUG-SENSITIVITY | MULTIDISCIPLINARY SCIENCES | Pharmacogenetics | Reproducibility of Results | Datasets as Topic | Neoplasms - genetics | Humans | Inhibitory Concentration 50 | Cell Line, Tumor - drug effects | Neoplasms - pathology | Databases, Factual | Neoplasms - drug therapy | Drugs | Studies | Datasets | Correlation analysis | Genomics | Pharmacology | Cancer | Index Medicus
Journal Article
by Menden, Michael P and Wang, Dennis and Mason, Mike J and Szalai, Bence and Bulusu, Krishna C and Guan, Yuanfang and Yu, Thomas and Kang, Jaewoo and Jeon, Minji and Wolfinger, Russ and Nguyen, Tin and Zaslavskiy, Mikhail and Abante, Jordi and Abecassis, Barbara Schmitz and Aben, Nanne and Aghamirzaie, Delasa and Aittokallio, Tero and Akhtari, Farida S and Al-lazikani, Bissan and Alam, Tanvir and Allam, Amin and Allen, Chad and de Almeida, Mariana Pelicano and Altarawy, Doaa and Alves, Vinicius and Amadoz, Alicia and Anchang, Benedict and Antolin, Albert A and Ash, Jeremy R and Aznar, Victoria Romeo and Ba-alawi, Wail and Bagheri, Moeen and Bajic, Vladimir and Ball, Gordon and Ballester, Pedro J and Baptista, Delora and Bare, Christopher and Bateson, Mathilde and Bender, Andreas and Bertrand, Denis and Wijayawardena, Bhagya and Boroevich, Keith A and Bosdriesz, Evert and Bougouffa, Salim and Bounova, Gergana and Brouwer, Thomas and Bryant, Barbara and Calaza, Manuel and Calderone, Alberto and Calza, Stefano and Capuzzi, Stephen and Carbonell-Caballero, Jose and Carlin, Daniel and Carter, Hannah and Castagnoli, Luisa and Celebi, Remzi and Cesareni, Gianni and Chang, Hyeokyoon and Chen, Guocai and Chen, Haoran and Chen, Huiyuan and Cheng, Lijun and Chernomoretz, Ariel and Chicco, Davide and Cho, Kwang-Hyun and Cho, Sunghwan and Choi, Daeseon and Choi, Jaejoon and Choi, Kwanghun and Choi, Minsoo and Cock, Martine De and Coker, Elizabeth and Cortes-Ciriano, Isidro and Cserzö, Miklós and Cubuk, Cankut and Curtis, Christina and Daele, Dries Van and Dang, Cuong C and Dijkstra, Tjeerd and Dopazo, Joaquin and Draghici, Sorin and Drosou, Anastasios and Dumontier, Michel and Ehrhart, Friederike and Eid, Fatma-Elzahraa and ElHefnawi, Mahmoud and Elmarakeby, Haitham and van Engelen, Bo and Engin, Hatice Billur and de Esch, Iwan and Evelo, Chris and Falcao, Andre O and Farag, Sherif and Fernandez-Lozano, Carlos and Fisch, Kathleen and Flobak, Asmund and Fornari, Chiara and Foroushani, Amir B. K and Fotso, Donatien Chedom and Fourches, Denis and ... and AstraZeneca-Sanger Drug Combinatio and AstraZeneca-Sanger Drug Combination DREAM Consortium
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2674 - 17
The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the... 
BREAST-CANCER | ANDROGEN RECEPTOR | INHIBITION | GENE | PATHWAY | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | MUTATIONS | CELL | RESOURCE | Identification methods | Pharmacology | Tumor cell lines | 1-Phosphatidylinositol 3-kinase | Antagonism | Computation | Cell lines | Computer applications | Predictions | Biomarkers | Bioindicators | Cancer | Tumors | Index Medicus
Journal Article