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1. Full Text Use of biomarkers to guide decisions on adjuvant systemic therapy forwomenwith early-stage invasive breast cancer: American Society of clinical Oncology clinical practice guideline
by Harris, Lyndsay N and Ismaila, Nofisat and McShane, Lisa M and Andre, Fabrice and Collyar, Deborah E and Gonzalez-Angulo, Ana M and Hammond, Elizabeth H and Kuderer, Nicole M and Liu, Minetta C and Mennel, Robert G and Van Poznak, Catherine and Bast, Robert C and Hayes, Daniel F
Journal of Clinical Oncology, ISSN 0732-183X, 04/2016, Volume 34, Issue 10, pp. 1134 - 1150
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2. Full Text Precision Medicine: Hype or Hoax?
by Mennel, Robert G
Baylor University Medical Center Proceedings, ISSN 0899-8280, 07/2015, Volume 28, Issue 3, pp. 397 - 400
Genetic aspects | Gene mutations | Lung cancer, Non-small cell | Drug therapy | Health aspects | Risk factors
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3. Full Text Use of biomarkers to guide decisions on systemic therapy for women with metastatic breast cancer: American Society of Clinical Oncology clinical practice guideline
by Van Poznak, Catherine and Somerfield, Mark R and Bast, Robert C and Cristofanilli, Massimo and Goetz, Matthew P and Gonzalez-Angulo, Ana M and Hicks, David G and Hill, Elizabeth G and Liu, Minetta C and Lucas, Wanda and Mayer, Ingrid A and Mennel, Robert G and Symmans, William F and Hayes, Daniel F and Harris, Lyndsay N
Journal of Clinical Oncology, ISSN 0732-183X, 08/2015, Volume 33, Issue 24, pp. 2695 - 2704
Purpose To provide recommendations on the appropriate use of breast tumor biomarker assay results to guide decisions on systemic therapy for metastatic breast... 
CIRCULATING TUMOR-CELLS | ONCOLOGY | PREDICTIVE BIOMARKERS | RECOMMENDATIONS | RECEPTOR 2 HER2 | MARKERS | PROGESTERONE-RECEPTOR | PROGNOSTIC VALUE | DOCETAXEL | ESTROGEN-RECEPTOR | TISSUE CONFIRMATION | Breast Neoplasms - therapy | Neoplasm Metastasis | Prospective Studies | Biomarkers, Tumor - analysis | Breast Neoplasms - pathology | United States | Humans | Biomarkers, Tumor - metabolism | Female | Breast Neoplasms - diagnosis | Breast Neoplasms - metabolism | Bc2 | Bc1 | Gdln1 | To2 | To4 | ASCO Special | To14
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4. Full Text Docetaxel With Cyclophosphamide Is Associated With an Overall Survival Benefit Compared With Doxorubicin and Cyclophosphamide: 7-Year Follow-Up of US Oncology Research Trial 9735
by Stephen Jones and Frankie Ann Holmes and Joyce O'Shaughnessy and Joanne L. Blum and Svetislava J. Vukelja and Kristi J. McIntyre and John E. Pippen and James H. Bordelon and Robert L. Kirby and John Sandbach and William J. Hyman and Donald A. Richards and Robert G. Mennel and Kristi A. Boehm and Wally G. Meyer and Lina Asmar and Daniel Mackey and Stefan Riedel and Hyman Muss and Michael A. Savin
Journal of Clinical Oncology, ISSN 0732-183X, 03/2009, Volume 27, Issue 8, pp. 1177 - 1183
Purpose We previously reported that four cycles of docetaxel/cyclophosphamide (TC) produced superior disease-free survival (DFS) compared with four cycles of... 
POSITIVE BREAST-CANCER | ADJUVANT CHEMOTHERAPY | PLUS CYCLOPHOSPHAMIDE | THERAPY | RANDOMIZED-TRIALS | ONCOLOGY | OLDER WOMEN | EXPERIENCE | LEUKEMIA | CONGESTIVE-HEART-FAILURE | PACLITAXEL | Cyclophosphamide - administration & dosage | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Breast Neoplasms - drug therapy | Cyclophosphamide - adverse effects | Taxoids - administration & dosage | Breast Neoplasms - chemistry | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adult | Breast Neoplasms - mortality | Aged | Receptor, ErbB-2 - analysis | Doxorubicin - adverse effects | Taxoids - adverse effects | Doxorubicin - administration & dosage | Index Medicus
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5. Full Text Precision Medicine: Hype or Hope?
by Mennel, Robert G
Baylor University Medical Center Proceedings, ISSN 0899-8280, 07/2015, Volume 28, Issue 3, pp. 397 - 400
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6. Full Text Phase III Trial Comparing Doxorubicin Plus Cyclophosphamide With Docetaxel Plus Cyclophosphamide As Adjuvant Therapy for Operable Breast Cancer
by Stephen E. Jones and Michael A. Savin and Frankie Ann Holmes and Joyce A. O'Shaughnessy and Joanne L. Blum and Svetislava Vukelja and Kristi J. McIntyre and John E. Pippen and James H. Bordelon and Robert Kirby and John Sandbach and William J. Hyman and Pankaj Khandelwal and Angel G. Negron and Donald A. Richards and Stephen P. Anthony and Robert G. Mennel and Kristi A. Boehm and Walter G. Meyer and Lina Asmar
Journal of Clinical Oncology, ISSN 0732-183X, 12/2006, Volume 24, Issue 34, pp. 5381 - 5387
Purpose The combination of doxorubicin and cyclophosphamide (AC) is a standard adjuvant chemotherapy regimen. Studies of docetaxel and cyclophosphamide (TC) in... 
REGIMEN | TRASTUZUMAB | ONCOLOGY | TAMOXIFEN | CHEMOTHERAPY | PACLITAXEL | Breast Neoplasms - surgery | Cyclophosphamide - administration & dosage | Prospective Studies | Nausea - chemically induced | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Survival Rate | Lymphatic Metastasis | Breast Neoplasms - drug therapy | Disease-Free Survival | Taxoids - administration & dosage | Vomiting - chemically induced | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Adult | Breast Neoplasms - mortality | Female | Aged | Neoplasm Staging | Neutropenia - chemically induced | Doxorubicin - administration & dosage
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7. Full Text Use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage invasive breast cancer: American society of clinical oncology clinical practice guideline focused update
by Krop, Ian and Ismaila, Nofisat and Andre, Fabrice and Bast, Robert C and Barlow, William and Collyar, Deborah E and Hammond, M. Elizabeth and Kuderer, Nicole M and Liu, Minetta C and Mennel, Robert G and Poznak, Catherine Van and Wolff, Antonio C and Stearns, Vered
Journal of Clinical Oncology, ISSN 0732-183X, 08/2017, Volume 35, Issue 24, pp. 2838 - 2847
Purpose This focused update addresses the use of MammaPrint (Agendia, Irvine, CA) to guide decisions on the use of adjuvant systemic therapy. Methods ASCO uses... 
VALIDATION | 70-GENE PROGNOSIS-SIGNATURE | ONCOLOGY | RECOMMENDATIONS | CHEMOTHERAPY | Decision Making | Humans | Decision Support Techniques | Biomarkers, Tumor - metabolism | Female | Chemotherapy, Adjuvant | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism
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8. Full Text Mammary-Type Myofibroblastoma with the Nephrotic Syndrome
by Colbert, Gates B and Vankawala, Preksha and Kuperman, Michael B and Mennel, Robert G
Baylor University Medical Center Proceedings, ISSN 0899-8280, 07/2016, Volume 29, Issue 3, pp. 318 - 320
We describe a 23-year-old white man who presented with anasarca and a new periumbilical mass. He had preserved kidney function and laboratory findings... 
Case studies | Complications and side effects | Development and progression | Care and treatment | Nephrotic syndrome | Skin cancer
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9. Full Text 2000 Update of Recommendations for the Use of Tumor Markers in Breast and Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology
by Robert C. Bast Jr and Peter Ravdin and Daniel F. Hayes and Susan Bates and Herbert Fritsche Jr and John M. Jessup and Nancy Kemeny and Gershon Y. Locker and Robert G. Mennel and Mark R. Somerfield and for the American Society of Clinical Oncology Tumor Markers Expert Panel and Amer Soc Clinical Oncology Tumor M and American Society of Clinical Oncology Tumor Markers Expert Panel
Journal of Clinical Oncology, ISSN 0732-183X, 03/2001, Volume 19, Issue 6, pp. 1865 - 1878
Objective: To update the 1997 clinical practice guidelines for the use of tumor marker tests in the prevention, screening, treatment, and surveillance of... 
ADJUVANT CHEMOTHERAPY | GROWTH-FACTOR RECEPTOR | POLYMERASE-CHAIN-REACTION | ONCOLOGY | C-ERBB-2 ANTIGEN LEVELS | HER-2/NEU GENE AMPLIFICATION | DNA-PLOIDY | CELL-PROLIFERATION | PROGNOSTIC-SIGNIFICANCE | PROGESTERONE-RECEPTOR | TOPOISOMERASE II-ALPHA | Prognosis | Biomarkers, Tumor - standards | Biomarkers, Tumor - analysis | Humans | Middle Aged | Male | Treatment Outcome | Colorectal Neoplasms - diagnosis | Breast Neoplasms - therapy | Disease-Free Survival | Colorectal Neoplasms - therapy | Mass Screening | Breast Neoplasms - pathology | Cost-Benefit Analysis | Quality of Life | Adult | Female | Aged | Biomarkers, Tumor - economics | Breast Neoplasms - diagnosis | Colorectal Neoplasms - pathology
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10. Full Text Exemestane Is Superior to Megestrol Acetate After Tamoxifen Failure in Postmenopausal Women With Advanced Breast Cancer: Results of a Phase III Randomized Double-Blind Trial
by Manfred Kaufmann and Emilio Bajetta and Luc Yves Dirix and Luis Enrique Fein and Stephen E. Jones and Nicoletta Zilembo and Jean-Louis Dugardyn and Cristina Nasurdi and Robert G. Mennel and Jozica Cervek and Camilla Fowst and Anna Polli and Enrico di Salle and Alexei Arkhipov and Gabriella Piscitelli and Langdon L. Miller and Giorgio Massimini and for the Exemestane Study Group and Exemestane Study Grp and for the Exemestane Study Group
Journal of Clinical Oncology, ISSN 0732-183X, 04/2000, Volume 18, Issue 7, pp. 1399 - 1411
Purpose: This phase ill, double-blind, randomized, multicenter study evaluated the efficacy, pharmacodynamics, and safety of the oral aromatase inactivator... 
ONCOLOGY | HORMONAL TREATMENT | STEROIDAL AROMATASE INHIBITOR | AMINOGLUTETHIMIDE | ENDOCRINE | ANASTROZOLE
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11. Full Text Case report: Whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies
by Zhrebker, Leah and Cherni, Irene and Gross, Lara M and Hinshelwood, Margaret M and Reese, Merrick and Aldrich, Jessica and Guileyardo, Joseph M and Roberts, William C and Craig, David and Von Hoff, Daniel D and Mennel, Robert G and Carpten, John D
BMC Cancer, ISSN 1471-2407, 01/2017, Volume 17, Issue 1, p. 17
Background: Primary cardiac angiosarcomas are rare, but they are the most aggressive type of primary cardiac neoplasms. When patients do present, it is with... 
Targeted therapies | Activating gene mutation | Cardiac angiosarcoma | Whole exome sequencing | MULTICENTER | ABNORMALITIES | PHASE-II | CANCER | TUMORS | TRANSPLANTATION | HEART | AMPLIFICATION | GENE | ONCOLOGY | MUTATIONS | Humans | Middle Aged | Male | Proto-Oncogene Proteins - genetics | Hemangiosarcoma - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Exome - genetics | Gene Amplification | Heart Neoplasms - genetics | DNA Mutational Analysis | Fatal Outcome | Mutation | Nuclear Proteins - genetics | Care and treatment | Gene mutations | Analysis | Development and progression | Genetic aspects | Nucleotide sequencing | Research | Angiosarcoma | DNA sequencing
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12. Full Text Randomized Phase III Trial of Pegylated Liposomal Doxorubicin Versus Vinorelbine or Mitomycin C Plus Vinblastine in Women With Taxane-Refractory Advanced Breast Cancer
by Alan M. Keller and Robert G. Mennel and Vassilis A. Georgoulias and Jean-Marc Nabholtz and Aura Erazo and Anna Lluch and Charles L. Vogel and Manfred Kaufmann and Gunther von Minckwitz and I. Craig Henderson and Lillian Mellars and Leila Alland and Craig Tendler
Journal of Clinical Oncology, ISSN 0732-183X, 10/2004, Volume 22, Issue 19, pp. 3893 - 3901
Purpose To compare the efficacy of pegylated liposomal doxorubicin (PLD) with that of a common salvage regimen (comparator) in patients with taxane-refractory... 
ONCOLOGY | CARCINOMA | Mitomycin - adverse effects | Doxorubicin - therapeutic use | Bridged-Ring Compounds - therapeutic use | Mitomycin - therapeutic use | Humans | Middle Aged | Salvage Therapy | Antineoplastic Combined Chemotherapy Protocols | Drug Resistance, Neoplasm | Vinblastine - therapeutic use | Breast Neoplasms - drug therapy | Taxoids - therapeutic use | Neoplasm Metastasis | Vinblastine - analogs & derivatives | Breast Neoplasms - pathology | Vinblastine - adverse effects | Adult | Female | Aged | Liposomes | Doxorubicin - adverse effects
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13. Full Text Phase 1 Trial of Bi-shRNA STMN1 BIV in Refractory Cancer
by Barve, Minal and Wang, Zhaohui and Kumar, Padmasini and Jay, Christopher M and Luo, Xiuquan and Bedell, Cynthia and Mennel, Robert G and Wallraven, Gladice and Brunicardi, Francis Charles and Senzer, Neil and Nemunaitis, John and Rao, Donald D
Molecular Therapy, ISSN 1525-0016, 06/2015, Volume 23, Issue 6, pp. 1123 - 1130
Stathmin1 (STMN1) is a microtubule modulator that is expressed in multiple cancers and correlates with poor survival. We previously demonstrated safety of... 
RNA INTERFERENCE | MEDICINE, RESEARCH & EXPERIMENTAL | SYSTEMIC DELIVERY | CELLS | SIRNA DELIVERY | OVEREXPRESSION | GASTRIC-CANCER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STATHMIN 1 | IN-VIVO | GENETICS & HEREDITY | MITOTIC SPINDLE | GENE-EXPRESSION | RNA, Small Interfering - genetics | Tubulin Modulators - pharmacology | Humans | Middle Aged | RNA, Messenger - genetics | Stathmin - genetics | Male | RNA, Messenger - metabolism | Drug Delivery Systems | Dose-Response Relationship, Drug | Stathmin - pharmacokinetics | Neoplasms - therapy | Neoplasms - genetics | Injections, Intralesional | Aged, 80 and over | Female | Aged | High-Throughput Nucleotide Sequencing | Plasmids - blood | Toxicity Tests | RNA, Small Interfering - metabolism | Index Medicus | Original
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14. Full Text Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline
by Harris, Lyndsay N and Ismaila, Nofisat and McShane, Lisa M and Andre, Fabrice and Collyar, Deborah E and Gonzalez-Angulo, Ana M and Hammond, Elizabeth H and Kuderer, Nicole M and Liu, Minetta C and Mennel, Robert G and Van Poznak, Catherine and Bast, Robert C and Hayes, Daniel F and American Society of Clinical Oncology
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, ISSN 0732-183X, 04/2016, Volume 34, Issue 10, pp. 1134 - 1150
To provide recommendations on appropriate use of breast tumor biomarker assay results to guide decisions on adjuvant systemic therapy for women with... 
Predictive Value of Tests | Humans | Antineoplastic Agents - therapeutic use | Receptors, Estrogen - analysis | Carcinoma, Ductal, Breast - mortality | Carcinoma, Ductal, Breast - chemistry | Receptors, Progesterone - analysis | Breast Neoplasms - chemistry | Carcinoma, Ductal, Breast - drug therapy | Urokinase-Type Plasminogen Activator - analysis | Antineoplastic Agents, Hormonal - therapeutic use | Carcinoma, Ductal, Breast - pathology | Female | Chemotherapy, Adjuvant | Reproducibility of Results | Biomarkers, Tumor - analysis | Comorbidity | Clinical Decision-Making - methods | Evidence-Based Medicine | Breast Neoplasms - drug therapy | Randomized Controlled Trials as Topic | Plasminogen Activator Inhibitor 1 - analysis | Disease-Free Survival | Breast Neoplasms - pathology | Survival Analysis | Breast Neoplasms - mortality | Receptor, ErbB-2 - analysis | Neoplasm Staging | Bc2 | Bc1 | Bc6 | Bc5 | Gdln1 | To2 | Bc7 | ASCO Special
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15. Full Text Robert Gary Mennel, MD: A Conversation with the Editor
by Mennel, Robert G and Roberts, William C
Baylor University Medical Center Proceedings, ISSN 0899-8280, 10/2006, Volume 19, Issue 4, pp. 374 - 385
Oncologists
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16. Full Text Tumor marker utility grading system: A framework to evaluate clinical utility of tumor markers
by Hayes, Daniel F and Bast, Robert C and Desch, Christopher E and Fritsche Jr, Herbert and Kemeny, Nancy E and Jessup, J. Milburn and Locker, Gershon Y and Macdonald, John S and Mennel, Robert G and Norton, Larry and Ravdin, Peter and Taube, Sheila and Winn, Rodger J
Journal of the National Cancer Institute, ISSN 0027-8874, 10/1996, Volume 88, Issue 20, pp. 1456 - 1466
Introduction of tumor markers into routine clinical practice has been poorly controlled, with few criteria or guidelines as to how such markers should be used.... 
CELL LUNG-CANCER | PROGNOSTIC FACTORS | PRACTICE GUIDELINES | SUPPRESSOR GENE | ONCOLOGY | C-ERBB-2 ANTIGEN LEVELS | SUSCEPTIBILITY GENE | OVARIAN-CANCER | DNA FLOW-CYTOMETRY | ESTROGEN-RECEPTOR | NEGATIVE BREAST-CANCER | Severity of Illness Index | Clinical Medicine | Predictive Value of Tests | Costs and Cost Analysis | Humans | Survival Analysis | Quality of Life | Neoplasms - diagnosis | Neoplasms - physiopathology | Neoplasms - pathology | Biomarkers, Tumor | Surveys and Questionnaires - standards | Physiological aspects | Tumor markers | Diagnosis | Cancer
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17. Full Text Mammary-type myofibroblastoma with the nephrotic syndrome
by Colbert, Gates B and Vankawala, Preksha and Kuperman, Michael B and Mennel, Robert G
Proceedings (Baylor University. Medical Center), ISSN 0899-8280, 07/2016, Volume 29, Issue 3, pp. 318 - 320
We describe a 23-year-old white man who presented with anasarca and a new periumbilical mass. He had preserved kidney function and laboratory findings... 
Case Studies
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18. A phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer
by Valero, Vicente and Jones, Stephen E and Von Hoff, Daniel D and Booser, Daniel J and Mennel, Robert G and Ravdin, Peter M and Holmes, Frankie A and Rahman, Zia and Schottstaedt, Margaret W and Erban, John K and Esparza-Guerra, Laura and Earhart, Robert H and Hortobagyi, Gabriel N and Burris III, Howard A
Journal of Clinical Oncology, ISSN 0732-183X, 1998, Volume 16, Issue 10, pp. 3362 - 3368
Purpose: To evaluate the efficacy and safety of docetaxel in patients with paclitaxel-resistant metastatic breast cancer (MBC). Patients and Methods: Docetaxel... 
TRIAL | THERAPY | ANALOG | ONCOLOGY | MICROTUBULES | TAXOL | RP-56976 | TAXOTERE | INFUSION | ANTHRACYCLINE-RESISTANT | Dexamethasone - administration & dosage | Drug Administration Schedule | Humans | Middle Aged | Paclitaxel - analogs & derivatives | Antiemetics - administration & dosage | Paclitaxel - adverse effects | Drug Resistance, Neoplasm | Breast Neoplasms - drug therapy | Paclitaxel - therapeutic use | Taxoids | Breast Neoplasms - pathology | Fever - etiology | Adult | Female | Nervous System Diseases - chemically induced | Aged | Edema - chemically induced | Antineoplastic Agents, Phytogenic - therapeutic use | Neutropenia - chemically induced | Antineoplastic Agents, Phytogenic - adverse effects
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19. Full Text Primary Effusion Lymphoma Diagnosed by Pericardiocentesis
by Nemunaitis, Michael C and Schussler, Jeffrey M and Shiller, S. Michelle and Sloan, Louis M and Mennel, Robert G
Baylor University Medical Center Proceedings, ISSN 0899-8280, 01/2009, Volume 22, Issue 1, pp. 77 - 80
Primary effusion lymphoma (PEL), formerly known as body cavity-based lymphoma, is a high-grade B-cell non-Hodgkin's lymphoma associated with Kaposi's sarcoma... 
Case studies | Lymphomas | Diagnosis | Surgery | Pericardium | Departments
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20. Full Text Phase II Study of Pemetrexed in Patients Pretreated with an Anthracycline, a Taxane, and Capecitabine for Advanced Breast Cancer
by O'Shaughnessy, Joyce A and Clark, Romnee S and Blum, Joanne L and Mennel, Robert G and Snyder, David and Ye, Zhishen and Liepa, Astra M and Melemed, Allen S and Yardley, Denise A
Clinical Breast Cancer, ISSN 1526-8209, 2005, Volume 6, Issue 2, pp. 143 - 149
This phase II study evaluated the efficacy, safety, and health outcomes of pemetrexed treatment in heavily pretreated patients with advanced breast cancer.... 
Toxicity | Vitamin supplementation | Multitargeted antifolates | Vitamin suplementation | Glutamates - therapeutic use | Glutamates - adverse effects | Capecitabine | Guanine - analogs & derivatives | Humans | Middle Aged | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Taxoids - therapeutic use | Deoxycytidine - therapeutic use | Antineoplastic Agents - adverse effects | Adult | Female | Guanine - adverse effects | Guanine - therapeutic use | Fluorouracil - analogs & derivatives | Treatment Outcome | Breast Neoplasms - drug therapy | Pemetrexed | Disease Progression | Antimetabolites, Antineoplastic - therapeutic use | Breast Neoplasms - pathology | Glutamates - administration & dosage | Aged | Anthracyclines - therapeutic use | Infusions, Intravenous | Deoxycytidine - analogs & derivatives | Guanine - administration & dosage
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