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Journal of Neurochemistry, ISSN 0022-3042, 06/2008, Volume 105, Issue 5, pp. 1770 - 1780
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/1997, Volume 336, Issue 2-3, pp. 275 - 281
Journal Article
Journal of the Neurological Sciences, ISSN 0022-510X, 2001, Volume 192, Issue 1, pp. 61 - 69
The present study compares the sensitivity to chronic exposure to glutamate agonists of SMI-32-positive rat-derived embryonic motoneurons under both mixed... 
NMDA | Motor neuron | AMPA | Kainate | l-NAME | Apoptosis | L-NAME | MOTOR-NEURONS | SERUM DEPRIVATION | PERMEABILITY | apoptosis | SPINAL-CORD | DEATH | TOXICITY | kainate | NEUROTOXICITY | NEUROSCIENCES | NEUROIMAGING | IN-VITRO | motor neuron | GLUTAMATE | RECEPTORS | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Anterior Horn Cells - drug effects | Anterior Horn Cells - metabolism | Amyotrophic Lateral Sclerosis - physiopathology | Receptors, N-Methyl-D-Aspartate - metabolism | Cell Communication - physiology | Dose-Response Relationship, Drug | Neuroglia - cytology | Drug Resistance - physiology | Fetus | Amyotrophic Lateral Sclerosis - etiology | Kainic Acid - toxicity | Cell Differentiation - physiology | Cell Survival - physiology | Receptors, AMPA - metabolism | Anterior Horn Cells - cytology | Cell Survival - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Magnesium - pharmacology | Rats, Sprague-Dawley | Neurotoxins - pharmacology | Animals | Excitatory Amino Acid Agonists - toxicity | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - toxicity | Glycine - pharmacology | Cell Differentiation - drug effects | Receptors, AMPA - agonists | Receptors, N-Methyl-D-Aspartate - agonists | Amyotrophic Lateral Sclerosis - metabolism | Cell Communication - drug effects | Neuroglia - metabolism | Neurotoxins - metabolism | Glutamic Acid - metabolism | Nitric Oxide - metabolism | N-Methylaspartate - toxicity | Receptors, AMPA - antagonists & inhibitors | Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 01/2012, Volume 80, Issue 1, pp. 46 - 53
A new delivery system based on drug cyclodextrin (Cd) complexation and loading into nanostructured lipid carriers (NLC) has been developed to improve... 
Nanostructured lipid carriers (NLC) | Polymeric cyclodextrins | Hydrogel | Topical formulation | Ketoprofen | VIVO | NLC | NANOPARTICLES SLN | TRANSDERMAL DELIVERY | COMPLEXES | INDOMETHACIN | SOLID-STATE | IN-VITRO | BETA-CYCLODEXTRIN | PHARMACOLOGY & PHARMACY | NAPROXEN | Polymers - administration & dosage | Chemistry, Pharmaceutical - methods | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Drug Carriers - administration & dosage | Delayed-Action Preparations - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Ketoprofen - chemistry | Lipids - chemistry | Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage | Cyclodextrins - chemistry | Epichlorohydrin - administration & dosage | Polysaccharides, Bacterial - chemistry | Polysaccharides, Bacterial - administration & dosage | Freeze Drying - methods | Drug Stability | Solubility | Ketoprofen - administration & dosage | Lipids - administration & dosage | Permeability | Particle Size | Epichlorohydrin - chemistry | beta-Cyclodextrins - administration & dosage | beta-Cyclodextrins - chemistry | Nanostructures - administration & dosage | Cyclodextrins - administration & dosage | Nanostructures - chemistry | Polymers - chemistry | Administration, Topical | Cyclodextrins | Dextrins | Transdermal medication | Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 01/2018, Volume 122, pp. 54 - 61
Previous studies proved the effectiveness of an intravenous PEGylated liposomal formulation of opiorphin (1 mg/mL) in protecting the drug from enzymatic... 
Ex vivo permeation | PEGylated liposomes | In situ nasal delivery | Mucoadhesion | Opiorphin | Thermosensitive hydrogel | DESIGN | HYDROGELS | DRUG-DELIVERY | TOLERANCE | FORMULATION | PEPTIDE | POLOXAMER | TEMPERATURE | PLA-PEG PARTICLES | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Peptides | Enzymes | Permeability | Index Medicus
Journal Article
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 08/2019, Volume 567, pp. 118454 - 118454
The performance of a series of inorganic salts as direct compression excipients was systematically evaluated. The physical-chemical and technological... 
Flowability | Compressibility | Inorganic pharmaceutical excipients | Direct compression tablets | Statistical ranking | COMPACTION | BINDER | EQUATIONS | DIHYDRATE | DICALCIUM PHOSPHATE | MICROCRYSTALLINE CELLULOSE | TABLETS | PHARMACOLOGY & PHARMACY | POWDER | STARCHES
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 11/2016, Volume 152, pp. 755 - 763
Two kinds of mucoadhesive buccal tablets of clonazepam (CLZ) were developed to provide, a prolonged local or systemic delivery respectively. Tablets prepared... 
Polymeric tablet | Buccal delivery | Cyclodextrin | POLYMER SCIENCE | DRUG-DELIVERY | CHEMISTRY, ORGANIC | DOSAGE FORMS | PATCHES | RELEASE | CHEMICALLY-MODIFIED CYCLODEXTRINS | SOLID-STATE | IN-VITRO | GEL FORMULATIONS | VITRO/IN-VIVO PERFORMANCE | BETA-CYCLODEXTRIN | CHEMISTRY, APPLIED | Clonazepam | Cyclodextrins | Transdermal medication | Dextrins | Permeability | Polymers | Index Medicus
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 11/2002, Volume 70, Issue 4, pp. 553 - 560
We studied the expression and distribution of glutamate receptor subtypes in the spinal cord of mnd mice, a model of motor neuron disorders and neuronal ceroid... 
ChAT | GluR4 | GluR3 | GluR2 | NMDAR1 | CA2+-PERMEABLE AMPA RECEPTORS | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | DEGENERATION | IMMUNOCYTOCHEMICAL LOCALIZATION | SELECTIVE VULNERABILITY |