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Nature Genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 186 - 190
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2006, Volume 12, Issue 8, pp. 2622 - 2627
Journal Article
PLoS Genetics, ISSN 1553-7390, 2013, Volume 9, Issue 12, p. e1003997
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2010, Volume 42, Issue 6, pp. 530 - 535
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2006, Volume 103, Issue 21, pp. 8078 - 8083
Genetic abnormalities that result in expression of chimeric tyrosine kinase proteins such as BCR-ABL1 and ETV6-PDGFR beta are common causes of hematopoietic... 
Tyrosine kinase | Leukemia | Oncogene | Fusion gene | leukemia | SIGNALING PATHWAYS | FUSION | PROTEIN | MULTIDISCIPLINARY SCIENCES | tyrosine kinase | oncogene | CHRONIC MYELOID-LEUKEMIA | fusion gene | IMATINIB | KIT | IDIOPATHIC HYPEREOSINOPHILIC SYNDROME | FACTOR-BETA RECEPTOR | GASTROINTESTINAL STROMAL TUMORS | RECEPTOR TYROSINE KINASE | Biological Sciences
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 09/2019, Volume 134, Issue 16, pp. 1323 - 1336
The PRC2 complex, with core components EZH2, SUZ12 and EED, is responsible for writing H3K27me3 histone marks associated with gene repression. Analysis of... 
Journal Article
Blood, ISSN 0006-4971, 08/2006, Volume 108, Issue 4, pp. 1374 - 1376
Abstract The FIP1L1-PDGFRA oncogene is a common cause of chronic eosinophilic leukemia (CEL), and encodes an activated tyrosine kinase that is inhibited by... 
Neoplasia
Journal Article
Haematologica, ISSN 0390-6078, 05/2011, Volume 96, Issue 5, pp. 779 - 783
Journal Article
PLoS Genetics, ISSN 1553-7390, 12/2013, Volume 9, Issue 12
  RNA-seq is a promising technology to re-sequence protein coding genes for the identification of single nucleotide variants (SNV), while simultaneously... 
Proteins | Transcription factors | Genomics | Genomes | Mutation | Grants | Kinases | Gene expression | Generalized linear models | Cancer
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1078 - 1078
Abstract Activation mutations in JAK3 occur in 16% of T-cell acute lymphoblastic leukemia (T-ALL) cases, and co-occur frequently with HOXA cluster... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 3575 - 3575
Abstract CRISPR/Cas genome editing is a powerful tool to precisely induce chromosomal breaks and to modify genes of interest. Cas9, an RNA-guided DNA... 
Journal Article
Cancer Cell, ISSN 1535-6108, 08/2018, Volume 34, Issue 2, pp. 271 - 285.e7
Journal Article