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1. Full Text Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial
by Bluth, T and Teichmann, R and Kiss, T and Bobek, I and Canet, J and Cinnella, G and de Baerdemaeker, L and Gregoretti, C and Hedenstierna, G and Hemmes, S. N and Hiesmayr, M and Hollmann, M. W and Jaber, S and Laffey, J. G and Licker, M. J and Markstaller, K and Matot, I and Müller, G and Mills, G. H and Mulier, J. P and Putensen, C and Rossaint, R and Schmitt, J and Senturk, M and Serpa Neto, A and Severgnini, P and Sprung, J and Vidal Melo, M. F and Wrigge, H and Schultz, M. J and Pelosi, P and Gama de Abreu, M and Güldner, Aneas and Huhle, Robert and Uhlig, Christopher and Vivona, Luigi and Bergamaschi, Alice and Rossaint, Rolf and Stevanovic, Ana and Treschan, Tanja and Schaefer, Maximilian and Kienbaum, Peter and Laufenberg-Feldmann, Rita and Bergmann, Lars and Ebner, Felix and Robitzky, Luisa and Mölders, Patrick and Unterberg, Matthias and Busch, Cornelius and de Hert, Stefan and PROBESE Investigators and Clinical Trial Network European S and PROtective VEntilation Netwo and Clinical Trial Network of the European Society of Anaesthesiology (ESA) and PROtective VEntilation Network (PROVEnet) and PROBESE investigators and on behalf of the Clinical Trial Network of the European Society of Anaesthesiology (ESA) and and the PROtective VEntilation Network (PROVEnet) and for the PROBESE investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Klinisk fysiologi
Trials, ISSN 1745-6215, 2017, Volume 18, Issue 1, pp. 202 - 22
Background: Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive... 
Obesity | Postoperative pulmonary complication | Positive end-expiratory pressure | Recruitment maneuver | Mechanical ventilation | MEDICINE, RESEARCH & EXPERIMENTAL | TIDAL VOLUMES | GENERAL-ANESTHESIA | RESPIRATORY-DISTRESS-SYNDROME | POSTOPERATIVE PULMONARY COMPLICATIONS | LUNG-VOLUMES | INTERNATIONAL CONSENSUS | LIVER-FAILURE | ALVEOLAR RECRUITMENT MANEUVER | DRIVING PRESSURE | Body Mass Index | Lung Diseases - diagnosis | Intraoperative Care - adverse effects | Obesity - complications | Humans | Lung Diseases - prevention & control | Risk Factors | Clinical Protocols | Positive-Pressure Respiration - adverse effects | Male | Obesity - physiopathology | Treatment Outcome | Lung - physiopathology | Anesthesia, General - adverse effects | Positive-Pressure Respiration - methods | Lung Diseases - etiology | Protective Factors | Time Factors | Intraoperative Care - methods | Female | Obesity - diagnosis | Lung Diseases - physiopathology | Research Design | Surgical Procedures, Operative - adverse effects | Prevention | Overweight persons | Usage | Complications | Surgery | Research | Comparative analysis | Health aspects | Artificial respiration | Life Sciences | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Lungmedicin och allergi | Klinisk medicin | Respiratory Medicine and Allergy
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2. Full Text Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial
by Bluth, T and Teichmann, R and Kiss, T and Bobek, I and Canet, J and Cinnella, G and De Baerdemaeker, L and Gregoretti, C and Hedenstierna, G and Hemmes, S N and Hiesmayr, M and Hollmann, M W and Jaber, S and Laffey, J G and Licker, M J and Markstaller, K and Matot, I and Müller, G and Mills, G H and Mulier, J P and Putensen, C and Rossaint, R and Schmitt, J and Senturk, M and Neto, A Serpa and Severgnini, P and Sprung, J and Vidal Melo, M F and Wrigge, H and Schultz, M J and Pelosi, P and Gama de Abreu, Marcelo and PROBESE investigators, and the PROtective VEntilation Network (PROVEnet) and on behalf of the Clinical Trial Network of the European Society of Anaesthesiology (ESA) and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Hedenstiernalaboratoriet and Uppsala universitet and Institutionen för medicinska vetenskaper and Institutionen för kirurgiska vetenskaper and Klinisk fysiologi
Trials, ISSN 1745-6215, 06/2017, Volume 18, Issue 1, p. 247
Clinical Medicine | Anaesthesiology and Intensive Care | Medical and Health Sciences | Medicin och hälsovetenskap | Anestesi och intensivvård | Anesthesiology and Intensive Care | Klinisk medicin | Anestesiologi och intensivvård
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3. Full Text High-Throughput Melting-Temperature Analysis of a Monoclonal Antibody by Differential Scanning Fluorimetry in the Presence of Surfactants
by Menzen, Tim and Friess, Wolfgang
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 02/2013, Volume 102, Issue 2, pp. 415 - 428
Differential scanning fluorimetry (DSF) is successfully used as a high-throughput screening method for the analysis of the protein melting temperature ( ) in... 
protein formulation | calorimetry (DSC) | surfactants | proteins | high throughput technologies | fluorescence spectroscopy | stability | thermal analysis | Fluorescence spectroscopy | Proteins | Stability | High throughput technologies | Calorimetry (DSC) | Thermal analysis | Protein formulation | Surfactants | AQUEOUS-SOLUTIONS | CHEMISTRY, MEDICINAL | DRUG DISCOVERY | PROMOTE PROTEIN STABILITY | CHEMISTRY, MULTIDISCIPLINARY | THERMAL SHIFT ASSAYS | REVERSIBLE SELF-ASSOCIATION | FLUORESCENCE | STATIC LIGHT-SCATTERING | PHARMACOLOGY & PHARMACY | MEMBRANE-PROTEINS | BINDING | THERMOFLUOR | Cricetinae | Animals | Antibodies, Monoclonal - analysis | Cricetulus | Humans | Calorimetry, Differential Scanning - methods | Fluorometry - methods | Surface-Active Agents - chemistry | Antibodies, Monoclonal - chemistry | Surface-Active Agents - analysis | CHO Cells | High-Throughput Screening Assays - methods | Fluorescence | Monoclonal antibodies | Surface active agents | Analysis | Denaturation
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