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1. Full Text Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease
by Nobili, Annalisa and Latagliata, Emanuele Claudio and Viscomi, Maria Teresa and Cavallucci, Virve and Cutuli, Debora and Giacovazzo, Giacomo and Krashia, Paraskevi and Rizzo, Francesca Romana and Marino, Ramona and Federici, Mauro and De Bartolo, Paola and Aversa, Daniela and Dell'Acqua, Maria Concetta and Cordella, Alberto and Sancandi, Marco and Keller, Flavio and Petrosini, Laura and Puglisi-Allegra, Stefano and Mercuri, Nicola Biagio and Coccurello, Roberto and Berretta, Nicola and D'Amelio, Marcello
Nature communications, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, pp. 14727 - 14727
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Inflammation - pathology | Alzheimer Disease - complications | Dihydroxyphenylalanine - therapeutic use | Apoptosis - drug effects | Dopaminergic Neurons - pathology | Memory | Selegiline - pharmacology | Neuronal Plasticity - drug effects | Dendritic Spines - metabolism | Hippocampus - drug effects | Alzheimer Disease - pathology | Inflammation - complications | Dopaminergic Neurons - metabolism | Dihydroxyphenylalanine - pharmacology | Dopaminergic Neurons - drug effects | Cell Death - drug effects | Selegiline - therapeutic use | Disease Models, Animal | Food | Nucleus Accumbens - pathology | Nucleus Accumbens - physiopathology | Alzheimer Disease - physiopathology | Ventral Tegmental Area - drug effects | Plaque, Amyloid - pathology | Ventral Tegmental Area - physiopathology | Ventral Tegmental Area - pathology | Alzheimer Disease - drug therapy | Mice, Transgenic | Hippocampus - pathology | Nerve Degeneration - complications | Nerve Degeneration - pathology | Plaque, Amyloid - complications | Animals | Plaque, Amyloid - physiopathology | Reward | Hippocampus - physiopathology | Nerve Degeneration - drug therapy | Index Medicus
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2. Full Text Reversal of dopamine‐mediated firing inhibition through activation of the dopamine transporter in substantia nigra pars compacta neurons
by Aversa, Daniela and Martini, Alessandro and Guatteo, Ezia and Pisani, Antonio and Mercuri, Nicola Biagio and Berretta, Nicola
British journal of pharmacology, ISSN 0007-1188, 09/2018, Volume 175, Issue 17, pp. 3534 - 3547
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Dopamine Plasma Membrane Transport Proteins - metabolism | Mesencephalon - cytology | Mesencephalon - metabolism | Mice, Inbred C57BL | Receptors, Dopamine D2 - agonists | Dopamine - pharmacology | Neurons - cytology | Substantia Nigra - metabolism | Substantia Nigra - cytology | Patch-Clamp Techniques | Substantia Nigra - drug effects | Animals | Mesencephalon - drug effects | Mice | Neurons - metabolism | In Vitro Techniques | Neurons - drug effects | Monoamine Oxidase - metabolism | Phenols | GABA | Cocaine | Neurons | γ-Aminobutyric acid B receptors | Dopamine | Mesencephalon | Substantia nigra | Stimulation | Antagonists | Pharmacology | Recovery | Sulpiride | Quinpirole | Receptors | Perfusion | Baclofen | Dopamine transporter | Inhibition | Dopamine D2 receptors | Transporter | Hyperpolarization | Index Medicus | Research Papers | Research Paper
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3. Full Text Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia
by Armogida, Marta and Nisticò, Robert and Mercuri, Nicola Biagio
British journal of pharmacology, ISSN 0007-1188, 06/2012, Volume 166, Issue 4, pp. 1211 - 1224
electrophysiology | neuroprotection | catalase | hydrogen peroxide | brain ischaemia | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neurology | Biological and medical sciences | Vascular diseases and vascular malformations of the nervous system | Medical sciences | Pharmacology. Drug treatments | Neuroprotective Agents - therapeutic use | Oxidoreductases - antagonists & inhibitors | Humans | Brain Ischemia - metabolism | Hippocampus - drug effects | Substantia Nigra - metabolism | Molecular Targeted Therapy | Corpus Striatum - metabolism | Brain Ischemia - enzymology | Neuroprotective Agents - pharmacology | Hippocampus - enzymology | Neurons - metabolism | Neurons - drug effects | Corpus Striatum - enzymology | Disease Models, Animal | Substantia Nigra - enzymology | Oxidoreductases - metabolism | Enzyme Inhibitors - pharmacology | Antioxidants - pharmacology | Enzyme Inhibitors - therapeutic use | Hydrogen Peroxide - metabolism | Hippocampus - metabolism | Antioxidants - therapeutic use | Substantia Nigra - drug effects | Animals | Reperfusion Injury - prevention & control | Signal Transduction - drug effects | Brain Ischemia - drug therapy | Hydrogen Peroxide - agonists | Neurons - enzymology | Corpus Striatum - drug effects | Hydrogen Peroxide - antagonists & inhibitors | Metabolism | Medical research | Stroke | Index Medicus | Reviews
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4. Full Text Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis
by Pieri, Massimo and Carunchio, Irene and Curcio, Livia and Mercuri, Nicola Biagio and Zona, Cristina
Experimental neurology, ISSN 0014-4886, 2009, Volume 215, Issue 2, pp. 368 - 379
ALS | Patch-clamp | Riluzole | Ionic channels | Persistent sodium current | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis | Medical sciences | Membrane Potentials - genetics | Superoxide Dismutase - genetics | Electric Stimulation | Humans | Cerebral Cortex - pathology | Sodium Channels - physiology | Patch-Clamp Techniques - methods | Ion Channel Gating - physiology | Neurons - physiology | Tetrodotoxin - pharmacology | Neurons - drug effects | Superoxide Dismutase - metabolism | Disease Models, Animal | Membrane Potentials - drug effects | Biophysical Phenomena | Amyotrophic Lateral Sclerosis - genetics | Cells, Cultured | Mice, Transgenic | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Membrane Potentials - physiology | Amyotrophic Lateral Sclerosis - pathology | Animals | Mice | Riluzole - pharmacology | Ion Channel Gating - drug effects | Neurons | Analysis | Superoxide dismutase | Amyotrophic lateral sclerosis | Genetic aspects | Superoxide | Index Medicus
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5. Full Text mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling
by Ledonne, Ada and Mercuri, Nicola Biagio
Frontiers in molecular neuroscience, ISSN 1662-5099, 10/2018, Volume 11, pp. 346 - 346
Dopamine | Neuregulin 1 | Substantia nigra | Synaptic plasticity | ErbB signaling | LTD | Group 1 metabotropic glutamate receptors (mGluRI) | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Tyrosine | Phenols | Glutamate | Neurons | Mesencephalon | ErbB protein | Brain slice preparation | Schizophrenia | Roles | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | ErbB-2 protein | Epidermal growth factor | Synaptic transmission | Neostriatum | Ligands | Neuregulin | Glutamatergic transmission | Psychiatry | Long-term depression | Glutamic acid receptors (metabotropic) | group 1 metabotropic glutamate receptors (mGluRI) | synaptic plasticity | dopamine | neuregulin 1
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6. Full Text Review: Parkinson's disease: from synaptic loss to connectome dysfunction
by Bellucci, Arianna and Mercuri, Nicola Biagio and Venneri, Annalena and Faustini, Gaia and Longhena, Francesca and Pizzi, Marina and Missale, Cristina and Spano, PierFranco
Neuropathology and applied neurobiology, ISSN 0305-1846, 02/2016, Volume 42, Issue 1, pp. 77 - 94
axonal damage | Parkinson's disease | synaptic loss | α‐synuclein | functional connectome | Pathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Parkinson Disease - pathology | Connectome | Synapses - pathology | Humans | Disease Progression | Nerve Degeneration - pathology | Parkinsons disease | Index Medicus
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