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08/2018
Se refiere a un anticuerpo aislado que se une especificamente a la proteina CTLA-4 humana que comprende una CDRH1 de secuencia de aminoacidos SYX1MX2 (SEQ ID... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
1972, Fondation nationale des sciences politiques. Travaux et recherches de science politique. Études maghrébines, 10, 174,2
Book
The New England Journal of Medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 23, pp. 2189 - 2199
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 517 - 520
Checkpoint blockade immunotherapies enable the host immune system to recognize and destroy tumour cells(1). Their clinical activity has been correlated with... 
CELL LUNG-CANCER | CTLA-4 BLOCKADE | MELANOMA | THERAPY | LANDSCAPE | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | RESISTANCE | CLINICAL-RESPONSE | REPERTOIRES | Humans | Lung Neoplasms - pathology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antigen Presentation | Melanoma - genetics | Immunotherapy | Cell Cycle Checkpoints - genetics | Cell Cycle Checkpoints - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Lymphocyte Activation | CTLA-4 Antigen - genetics | Lung Neoplasms - therapy | Melanoma - pathology | CTLA-4 Antigen - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Carcinoma, Non-Small-Cell Lung - therapy | Lung Neoplasms - immunology | Models, Immunological | Melanoma - immunology | Survival Analysis | T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - immunology | CTLA-4 Antigen - antagonists & inhibitors | Melanoma - therapy | Programmed Cell Death 1 Receptor - genetics | Cohort Studies | Evolution, Molecular | Antigens | Care and treatment | Patient outcomes | Models | Health aspects | Tumors | Medical research | Peptides | PD-1 protein | Lung cancer | Melanoma | Cytotoxicity | Lymphocytes T | Patients | Proteins | Cell recognition | CTLA-4 protein | Major histocompatibility complex | Immune checkpoint | Lymphocytes | Evolution | Mutation | Histocompatibility | Cancer | Immune system | Fitness
Journal Article
Science, ISSN 0036-8075, 03/2016, Volume 351, Issue 6280, pp. 1463 - 1469
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2018, Volume 378, Issue 21, pp. 1976 - 1986
Journal Article
by Balachandran, Vinod P and Luksza, Marta and Zhao, Julia N and Makarov, Vladimir and Moral, John Alec and Remark, Romain and Herbst, Brian and Askan, Gokce and Bhanot, Umesh and Senbabaoglu, Yasin and Wells, Daniel K and Cary, Charles Ian Ormsby and Grbovic-Huezo, Olivera and Attiyeh, Marc and Medina, Benjamin and Zhang, Jennifer and Loo, Jennifer and Saglimbeni, Joseph and Abu-Akeel, Mohsen and Zappasodi, Roberta and Riaz, Nadeem and Smoragiewicz, Martin and Kelley, Z. Larkin and Basturk, Olca and Gönen, Mithat and Levine, Arnold J and Allen, Peter J and Fearon, Douglas T and Merad, Miriam and Gnjatic, Sacha and Iacobuzio-Donahue, Christine A and Wolchok, Jedd D and DeMatteo, Ronald P and Chan, Timothy A and Greenbaum, Benjamin D and Merghoub, Taha and Leach, Steven D and Australian Pancreatic Canc Genom and Garvan Institute of Medical Research and Bankstown Hospital and St Vincent’s Hospital and Royal Adelaide Hospital and Royal North Shore Hospital and Envoi Pathology and QIMR Berghofer Medical Research Institute and Prince of Wales Hospital and University of Melbourne, Centre for Cancer Research and University of Queensland, Institute for Molecular Bioscience and Royal Prince Alfred Hospital, Chris O’Brien Lifehouse and Princess Alexandria Hospital and Fremantle Hospital and Liverpool Hospital and Austin Hospital and University of Glasgow and Johns Hopkins Medical Institutes and Flinders Medical Centre and Westmead Hospital and St John of God Healthcare and ARC-Net Centre for Applied Research on Cancer and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. S12 - S16
Journal Article
Journal Article