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Physiological Reports, 10/2018, Volume 6, Issue 20, pp. e13889 - n/a
Neonatal pulmonary vascular disease (PVD) is increasingly recognized as a disease that complicates the cardiopulmonary adaptations after birth and predisposes... 
hypoxia | nitric oxide | Exercise | soluble guanylyl cyclase | pulmonary vascular disease | Adaptations | Neonates | Lung diseases | Guanylate cyclase | Arteries | Vasodilation | Endothelium | Hogs | Vascular diseases | Cyclic GMP | Nitric oxide | Hypoxia | Phosphodiesterase
Journal Article
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2014, Volume 306, Issue 5, pp. L442 - L452
textabstractBoth phosphodiesterase 5 (PDE5) inhibition and endothelin (ET) receptor blockade have been shown to induce pulmonary vasodilation. However, little... 
Big ET | Exercise | Pulmonary vascular tone | PDE5 inhibition | PHYSIOLOGY | RECEPTOR BLOCKADE | MYOCARDIAL-INFARCTION | ORAL SILDENAFIL | HEART-FAILURE | exercise | VASOMOTOR TONE | VASCULAR-TONE | OXYGEN-UPTAKE | TREADMILL EXERCISE | RESPIRATORY SYSTEM | ARTERIAL-HYPERTENSION | ETA/ETB receptor blockade | NITRIC-OXIDE | pulmonary vascular tone | Tetrazoles - pharmacology | Humans | Male | Endothelins - metabolism | Pulmonary Circulation - physiology | Vasoconstriction - physiology | Endothelin A Receptor Antagonists | Female | Phosphodiesterase 5 Inhibitors - pharmacology | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Vasoconstrictor Agents - pharmacology | Endothelins - antagonists & inhibitors | Endothelin B Receptor Antagonists | Physical Conditioning, Animal - physiology | Vasoconstriction - drug effects | Drug Synergism | Animals | Cyclic GMP - metabolism | Signal Transduction - drug effects | Receptor, Endothelin A - metabolism | Signal Transduction - physiology | Pulmonary Circulation - drug effects | Pyridines - pharmacology | Receptor, Endothelin B - metabolism | Sus scrofa | Medical research | Dilatation | Vasodilators | Vasoconstriction | Physiological aspects | Blood vessels | Medicine, Experimental | Dosage and administration | Research | Phosphodiesterases | ETA | ETB receptor blockade
Journal Article
Cardiovascular Research, ISSN 0008-6363, 2017, Volume 113, Issue 11, pp. 1273 - 1275
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2018, Volume 314, Issue 3, pp. H603 - H615
Pulmonary vascular disease (PVD) represents an underestimated and increasing clinical burden not only in the neonatal period but also later in life, when... 
Hypoxia | Pulmonary vascular disease | Exercise | Sex | Perinatal programming | hypoxia | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CIRCULATION | sex | EARLY-STAGE | exercise | EXERCISE CAPACITY | CLINICAL-FEATURES | perinatal programming | pulmonary vascular disease | BRONCHOPULMONARY DYSPLASIA | EXTRA-UTERINE LIFE | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | OUTCOMES | HYPERTENSION | Vascular Remodeling | Hyperoxia - physiopathology | Hypertension, Pulmonary - diagnostic imaging | Hypertension, Pulmonary - physiopathology | Male | Hypertrophy, Right Ventricular - etiology | Pulmonary Artery - diagnostic imaging | Hypertrophy, Right Ventricular - physiopathology | Arterial Pressure | Time Factors | Hyperoxia - complications | Female | Hypertrophy, Right Ventricular - pathology | Ventricular Dysfunction, Right - physiopathology | Disease Models, Animal | Animals, Newborn | Echocardiography | Pulmonary Artery - physiopathology | Disease Progression | Hyperoxia - pathology | Animals | Ventricular Dysfunction, Right - etiology | Exercise Tolerance | Sex Factors | Hypertension, Pulmonary - etiology | Hypertension, Pulmonary - pathology | Sus scrofa | Pulmonary Artery - pathology | Ventricular Dysfunction, Right - pathology | Ventricular Function, Right | Infants (Newborn) | Physiological aspects | Lung diseases | Diseases
Journal Article
Netherlands Heart Journal, ISSN 1568-5888, 12/2015, Volume 23, Issue 12, pp. 576 - 577
Journal Article
American Journal of Physiology, ISSN 0363-6135, 03/2018, Volume 314, Issue 3, p. H603
Pulmonary vascular disease (PVD) represents an underestimated and increasing clinical burden not only in the neonatal period but also later in life, when... 
Heart | Hypertension | Neonates | Animal models | Arterioles | Complications | Lung diseases | Cardiovascular disease | Exposure | Pulmonary hypertension | Pulmonary artery | Hogs | Vascular diseases | Animals | Newborn babies | Swine | Respiratory diseases | Hypoxia | Blood pressure | Livestock | Ventricle | Thickening | Structure-function relationships
Journal Article
Netherlands Heart Journal, ISSN 1568-5888, 01/2014, Volume 22, Issue 7-8, pp. 326 - 327
Journal Article
BioEssays, ISSN 0265-9247, 03/2018, Volume 40, Issue 3, p. n/a
Introduction of O2 to Earth's early biosphere stimulated remarkable evolutionary adaptations, and a wide range of electron acceptors allowed diverse,... 
free radicals | evolution | complex life | oxygen | Adaptations | Cellular manufacture | Oxygen | Hydrogen peroxide | Biological evolution | Metabolism | Signaling | Pathways | Energy | Biosphere | Evolution | Metabolic pathways | Oxidation
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 09/2019, Volume 141, Issue 1, pp. 64 - 69
Activation of both adenosine A and A receptors (A R) contributes to coronary vasodilation. We previously demonstrated that uridine adenosine tetraphosphate (Up... 
Up4A | Relaxation | Adenosine | Coronary microcirculation | Smooth muscle cells
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2017, Volume 113, Issue 9, pp. 1035 - 1045
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2018, Volume 315, Issue 6, pp. L951 - L964
Pulmonary vascular remodeling in pulmonary arterial hypertension involves perturbations in the nitric oxide (NO) and endothelin-1 (ET-1) pathways. However. the... 
Pulmonary vascular remodeling | Endothelin | Exercise | CTEPH | Nitric oxide | nitric oxide | ACTIVATION | PHYSIOLOGY | SWINE | exercise | RECEPTOR | EXERCISE CAPACITY | ENDOTHELIAL FUNCTION | PATHOPHYSIOLOGY | endothelin | pulmonary vascular remodeling | RESPIRATORY SYSTEM | ARTERIAL-HYPERTENSION | RIOCIGUAT | NITRIC-OXIDE | GAS-EXCHANGE
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 10/2017, Volume 8, Issue OCT, p. 517
Journal Article