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1994, Volume 5, issue 1., 90
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Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7639, pp. 36 - 38
In the 1960s, the science-fiction television series Star Trek presented a vision of the future in which physician Dr Leonard McCoy used a portable diagnostic... 
Pattern recognition | Medical diagnosis | Dermatology | Artificial intelligence | Skin cancer
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2011, Volume 17, Issue 19, pp. 6118 - 6124
Journal Article
Nature, ISSN 0028-0836, 08/2017, Volume 548, Issue 7669, pp. 537 - 542
Somatic gene mutations can alter the vulnerability of cancer cells to T-cell-based immunotherapies. Here we perturbed genes in human melanoma cells to mimic... 
CELL LUNG-CANCER | METASTATIC MELANOMA | DIFFERENTIAL GENE | CTLA-4 BLOCKADE | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | RECEPTOR | T-CELLS | GENOME | LYMPHOCYTES | Neoplasms - metabolism | Humans | Genome - genetics | Adoptive Transfer | Janus Kinase 1 - metabolism | T-Lymphocytes, Cytotoxic - drug effects | Apelin - metabolism | Neoplasms - therapy | Apelin Receptors - genetics | Neoplasms - genetics | Melanoma - genetics | Immunotherapy | Female | Genes, Essential - genetics | Melanoma - metabolism | T-Lymphocytes, Cytotoxic - immunology | Knowledge Bases | Reproducibility of Results | Histocompatibility Antigens Class I - immunology | Antigen Presentation - genetics | CRISPR-Cas Systems - genetics | Apelin Receptors - metabolism | Animals | T-Lymphocytes, Cytotoxic - metabolism | Melanoma - immunology | Neoplasms - immunology | Interferon-gamma - immunology | Cell Line, Tumor | Mice | Mutation | Melanoma - therapy | Care and treatment | Genetic aspects | Nucleotide sequencing | Methods | DNA sequencing | Cancer | Cytolytic activity | Animal models | CD8 antigen | Genes | Genomics | Effector cells | Genomes | Lymphocytes T | Kinases | Cancer therapies | Lymphocytes | Janus kinase | Antigen presentation | Antigens | CRISPR | Melanoma | T cell receptors | Tumor cell lines | Signaling | Immune checkpoint | γ-Interferon | Interferon | Tumors
Journal Article
Cell, ISSN 0092-8674, 09/2015, Volume 163, Issue 1, pp. 39 - 53
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 4114 - 4114
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2011, Volume 17, Issue 19, pp. 6118 - 6124
Interferon- gamma is a cytokine whose biological activity is conventionally associated with cytostatic/cytotoxic and antitumor mechanisms during cell-mediated... 
Journal Article
Laboratory Investigation, ISSN 0023-6837, 06/2017, Volume 97, Issue 6, pp. 698 - 705
Journal Article
PLOS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0165102
Aims Cutaneous malignant melanoma is among the deadliest human cancers, broadly resistant to most clinical therapies. A majority of patients with BRAF(V600E)... 
CELLS | APOPTOSIS | MCL-1 | MULTIDISCIPLINARY SCIENCES | RESISTANCE | TUMOR-SUPPRESSOR | MICE | MALIGNANT-MELANOMA | ULTRAVIOLET-RADIATION | CANCER | SITE POLYMORPHISM | Genomics | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | MicroRNAs - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Melanoma - genetics | Proteolysis | Indoles - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Drug Therapy, Combination | Neoplasm Proteins - genetics | Genes, Tumor Suppressor | Oncogenes | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | RNA, Messenger - genetics | Carcinogenesis - genetics | Signal Transduction - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Carcinogenesis - pathology | Drug Synergism | Gossypol - pharmacology | Animals | Cell Line, Tumor | Gossypol - analogs & derivatives | Mice | MicroRNAs - genetics | Cell Transformation, Neoplastic - drug effects | Proteasome Endopeptidase Complex - metabolism | Cell Transformation, Neoplastic - pathology | MicroRNA | Analysis | Genes | Melanoma | Genetically modified organisms | Development and progression | Genetic engineering | Therapy | Animal models | MiRNA | Melanocytes | Gene expression | Mcl-1 protein | Skin cancer | 1-Phosphatidylinositol 3-kinase | Ribonucleic acids | Rodents | Tumor suppressor genes | Mutation | PTEN protein | Tumors
Journal Article
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 11/2017, Volume 30, Issue 6, pp. 509 - 510
Journal Article