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2015, First edition., Methods in enzymology, ISBN 0128022930, Volume 561
Web Resource
Methods in Enzymology, ISSN 0076-6879, 09/2015, Volume 561, pp. xv - xvi
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2016, Volume 18, Issue 6, p. 589
  Metabolic rewiring is essential for cancer cell survival. PGC1α, a transcriptional co-activator that is downregulated in prostate cancer, is now shown to... 
Transcription factors | Cell metabolism | Development and progression | Genetic aspects | Properties | Gene expression | Prostate cancer | Health aspects
Journal Article
Cancer and Metabolism, ISSN 2049-3002, 09/2015, Volume 3, Issue 1, pp. 1 - 1
Unchecked growth and proliferation is a hallmark of cancer, and numerous oncogenic mutations reprogram cellular metabolism to fuel these processes. As a... 
Mitochondria | Amino acids | Biosynthesis | Nucleotides | Lipogenesis | Anaplerosis | Cancer | Physiological aspects | Genetic aspects | Fatty acids
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 2009, Volume 144, Issue 3, pp. 167 - 174
Journal Article
2011, ISBN 9780128022931, 424
Metabolic Analysis Using Stable Isotopes, the newest volume in Methods in Enzymology continues the legacy of this premier serial with quality chapters authored... 
Metabolism | Pre-clinical Medicine: Basic Sciences
eBook
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1978, pp. 219 - 241
Metabolism plays a central role in virtually all diseases, including diabetes, cancer, and neurodegeneration. Detailed analysis is required to identify the... 
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7381, pp. 380 - 384
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and protein acetylation. In the conventional view of mammalian cell... 
FLUX ANALYSIS | DISTRIBUTIONS | FATTY-ACID SYNTHESIS | MULTIDISCIPLINARY SCIENCES | GROWTH | HYDROXYLATION | CELL-PROLIFERATION | SUPPRESSION | HIF-ALPHA | CANCER | DEHYDROGENASE | CD8-Positive T-Lymphocytes - cytology | Palmitic Acid - metabolism | Isocitrate Dehydrogenase - deficiency | Humans | Glutamine - metabolism | Kidney Neoplasms - metabolism | Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism | Oxygen - metabolism | Cell Hypoxia | Basic Helix-Loop-Helix Transcription Factors - metabolism | Acetyl Coenzyme A - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Ketoglutaric Acids - metabolism | Lipogenesis | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Carbon - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Oxidation-Reduction | Carcinoma, Renal Cell - pathology | Cells, Cultured | Isocitrate Dehydrogenase - genetics | Acetyl Coenzyme A - metabolism | Citric Acid Cycle | Carcinoma, Renal Cell - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Kidney Neoplasms - pathology | Physiological aspects | Hypoxia | Research | Lipid metabolism | Electron transport | Proteins | Confidence intervals | Metabolites | Lipids | Biosynthesis | Glucose | Experiments | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2012, Volume 8, Issue 10, pp. 839 - 847
Cancer cells engage in a metabolic program to enhance biosynthesis and support cell proliferation. The regulatory properties of pyruvate kinase M2 (PKM2)... 
ISOZYME | INHIBITION | FRUCTOSE-1,6-BISPHOSPHATE | THYROID-HORMONE | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOFORM | BINDING PROTEIN | CANCER-CELL METABOLISM | TUMOR-GROWTH | NUCLEAR TRANSLOCATION | Genes | Cells | Cancer | Tumors | Index Medicus | BASIC BIOLOGICAL SCIENCES
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 523 - n/a
Oncogenes such as K‐ ras mediate cellular and metabolic transformation during tumorigenesis. To analyze K‐Ras‐dependent metabolic alterations, we employed 13 C... 
cancer | metabolism | transcriptional analysis | metabolic flux analysis | Ras | MOUSE FIBROBLASTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL METABOLISM | TRANSFORMED FIBROBLASTS | LINES | P53 | FLUX ANALYSIS | DATABASE | AEROBIC GLYCOLYSIS | GENE-EXPRESSION | MUTATIONS | Neoplasms - metabolism | NIH 3T3 Cells | Cell Proliferation | Gas Chromatography-Mass Spectrometry | Oligonucleotide Array Sequence Analysis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Gene Expression Regulation, Neoplastic | Glutamine - metabolism | Gene Expression Profiling | Flow Cytometry | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Isotope Labeling | Fibroblasts - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Cell Transformation, Neoplastic - metabolism | Citric Acid Cycle | Animals | Cell Line, Tumor | Glucose - metabolism | Glycolysis | Fibroblasts - cytology | Mice | Neoplasms - pathology | Cell Line, Transformed | Tricarboxylic acid cycle | Transformation | Profiling | Downstream effects | Oxidative metabolism | Glucose | Proteins | Mitochondria | Alterations | Stable isotopes | Fluctuations | Metabolism | Gene expression | Organic chemistry | Computer applications | Transformations | Tracers | System effectiveness | Biotechnology | Reactive oxygen species | Transcription | Change detection | Genes | Amino acids | Intracellular signalling | Pyruvic acid | Biosynthesis | Myc protein | Kinases | Glucose metabolism | Metabolic flux | Metabolites | Carbon 13 | Adenine | Tumor cell lines | Fluxes | Nutrient uptake | Nitrogen | Carbon | Intermediates | Carbon cycle | Decoupling | Cell lines | Intracellular | Lactic acid | Apoptosis | Glutamine | Cancer | Index Medicus
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2011, Volume 43, Issue 9, pp. 869 - 874
Journal Article