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1. Full Text Neonatal screening for lysosomal storage disorders: feasibility and incidence from a nationwide study in Austria
by Mechtler, Thomas P, MD and Stary, Susanne, PhD and Metz, Thomas F, MSc and De Jesús, Víctor R, PhD and Greber-Platzer, Susanne, MD and Pollak, Arnold, Prof and Herkner, Kurt R, PhD and Streubel, Berthold, Prof and Kasper, David C, PhD
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9813, pp. 335 - 341
Summary Background The interest in neonatal screening for lysosomal storage disorders has increased substantially because of newly developed enzyme replacement... 
Internal Medicine | POMPE-DISEASE | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | THERAPY | ASSAY | METABOLISM | FABRY-DISEASE | TANDEM MASS-SPECTROMETRY | DRIED BLOOD SPOTS | KRABBE-DISEASE | INBORN-ERRORS | alpha-Galactosidase - genetics | Sphingomyelin Phosphodiesterase - genetics | Glucosylceramidase - genetics | Fabry Disease - genetics | Glucosylceramidase - blood | Humans | Male | Neonatal Screening | Incidence | Lysosomal Storage Diseases - diagnosis | Female | Niemann-Pick Diseases - diagnosis | Niemann-Pick Diseases - genetics | Infant, Newborn | alpha-Glucosidases - blood | Glycogen Storage Disease Type II - genetics | Lysosomal Storage Diseases - epidemiology | Austria - epidemiology | Lysosomal Storage Diseases - genetics | alpha-Galactosidase - blood | alpha-Glucosidases - genetics | Gaucher Disease - genetics | Glycogen Storage Disease Type II - diagnosis | Mutation | Fabry Disease - diagnosis | Gaucher Disease - diagnosis | Sphingomyelin Phosphodiesterase - blood | Metabolism, Inborn errors of | Infants (Newborn) | Usage | Medical examination | Diagnosis | Research | Babies | Quality control | Cystic fibrosis | Medical screening | Metabolism | Disease control | Blood | Metabolic disorders
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2. Full Text 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial
by Halliday, Alison, Prof and Harrison, Michael, Prof and Hayter, Elizabeth, BMus and Kong, Xiangling, MSc and Mansfield, Averil, Prof and Marro, Joanna, MSc and Pan, Hongchao, PhD and Peto, Richard, Prof and Potter, John, Prof and Rahimi, Kazem, DM and Rau, Angela, MBBS and Robertson, Steven, BA and Streifler, Jonathan, MD and Thomas, Dafydd, Prof and Asymptomatic Carotid Surg Trial AC and Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9746, pp. 1074 - 1084
Summary Background If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Primary Prevention | Stroke - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Treatment Outcome | Carotid Stenosis - complications | Incidence | Endarterectomy, Carotid - mortality | Stroke - etiology | Time Factors | Carotid Stenosis - mortality | Aged, 80 and over | Female | Stroke - epidemiology | Aged | Carotid Stenosis - surgery | Stroke (Disease) | Prevention | Care and treatment | Carotid artery diseases | Patient outcomes | Research | Endarterectomy | Health aspects | Risk factors | Medical imaging | Heart attacks | Drug therapy | Physicians | Mortality | Veins & arteries | Medical and Health Sciences | Medicin och hälsovetenskap
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3. Full Text American Society of Echocardiography Cardiovascular Technology and Research Summit: A Roadmap for 2020
by Pellikka, Patricia A., MD, FASE and Douglas, Pamela S., MD, FASE and Miller, James G., PhD and Abraham, Theodore P., MD, FASE and Baumann, Rolf and Buxton, Denis B., PhD and Byrd, Benjamin F., MD, FASE and Chen, Peter, PhD and Cook, Nakela L., MD, MPH and Gardin, Julius M., MD, MBA, FASE and Hansen, Gunnar, MSc and Houle, Hélène C., BA, RDCS, RVT, RDMS, FASE and Husson, Stefan, MSc and Kaul, Sanjiv, MD, FASE and Klein, Allan L., MD, FASE and Lang, Roberto M., MD, FASE and Leong-Poi, Howard, MD, FASE and Lopez, Hector, ScD and Mahmoud, Tamer M and Maslak, Sam, ScD and McCulloch, Marti L., MBA, RDCS, FASE and Metz, Steve, MS and Nagueh, Sherif F., MD, FASE and Pearlman, Alan S., MD, FASE and Pibarot, Philippe, DVM, PhD, FASE and Picard, Michael H., MD, FASE and Porter, Thomas R., MD, FASE and Prater, David and Rodriguez, Rudy and Sarano, Maurice E., MD and Scherrer-Crosbie, Marielle, MD, PhD, FASE and Shirali, Girish S., MBBS, FASE and Sinusas, Albert, MD and Slosky, Jack J., PhD, MBA and Sugeng, Lissa, MD, MPH and Tatpati, Anand and Villanueva, Flordeliza S., MD and von Ramm, Olaf T., PhD and Weissman, Neil J., MD, FASE and Zamani, Shaun
Journal of the American Society of Echocardiography, ISSN 0894-7317, 2013, Volume 26, Issue 4, pp. 325 - 338
To realize the great potential of ultrasound for improving patient outcomes and offering novel therapy, closer partnerships among scientists, engineers, and... 
Cardiovascular | Echocardiography | Cardiovascular imaging | Cardiovascular technology | Therapeutic ultrasound | Research | Contrast echocardiography | Valvular heart disease | Research training | Cardiac imaging | Clinical Research | Research infrastructure | Myocardial deformation | Three-dimensional imaging | Doppler | Cardiovascular technology development | EAE/ASE RECOMMENDATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | MICROBUBBLES | STRAIN | QUANTIFICATION | REGIONAL MYOCARDIAL-FUNCTION | VALVULAR HEART-DISEASE | DIAGNOSTIC ULTRASOUND | INVESTIGATORS | IN-VIVO | 3-DIMENSIONAL ECHOCARDIOGRAPHY | Bioengineering | Congresses as Topic | Humans | Cardiovascular Diseases - therapy | Ultrasonography, Interventional | Interprofessional Relations | Cardiovascular System | Equipment Design | Ultrasonography - trends | Technology Assessment, Biomedical | Ultrasonic Therapy | Cardiovascular Diseases - diagnostic imaging | Echocardiography - standards | Echocardiography, Doppler | Thrombolytic Therapy - methods | Registries | Software | Imaging, Three-Dimensional | Cardiovascular Diseases - diagnosis | Communication | Echocardiography - trends | Medical colleges | Equipment and supplies | Technical societies | Image processing | Trade and professional associations
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4. Full Text Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women
by Tran, Anna Hoang and Best, Brookie M and Stek, Alice and Wang, Jiajia and Capparelli, Edmund V and Burchett, Sandra K and Kreitchmann, Regis and Rungruengthanakit, Kittipong and George, Kathleen and Cressey, Tim R and Chakhtoura, Nahida and Smith, Elizabeth and Shapiro, David E and Mirochnick, Mark and IMPAACT P1026s Protocol Team
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 02/2016, Volume 72, Issue 3, pp. 289 - 296
BACKGROUND:Rilpivirine pharmacokinetics are defined by its absorption, distribution, metabolism, and excretion. Pregnancy can affect these factors by changes... 
pharmacokinetics | HIV | pregnancy | rilpivirine | TWICE | STEADY-STATE PHARMACOKINETICS | INFECTIOUS DISEASES | SAFETY | IMMUNOLOGY | ANTIRETROVIRALS | EFAVIRENZ | PHARMACOGENETICS | EXPOSURE | DRUG-METABOLISM | HIV Infections - blood | HIV Protease Inhibitors - blood | Pregnancy Trimester, Second | Prospective Studies | Follow-Up Studies | Humans | Rilpivirine - pharmacokinetics | Treatment Outcome | Postpartum Period | Pregnancy Trimester, Third | Pregnancy | Young Adult | Cytochrome P-450 CYP3A - blood | HIV Protease Inhibitors - pharmacokinetics | Rilpivirine - blood | Anti-HIV Agents - pharmacokinetics | Fetal Blood - chemistry | Adolescent | Pregnancy Complications, Infectious - blood | Adult | Female | Anti-HIV Agents - blood | Infant, Newborn
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5. Full Text Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions
by Espeland, Mark A and Probstfield, Jeffery and Hire, Donald and Redmon, J. Bruce and Evans, Gregory W and Coday, Mace and Lewis, Cora E and Johnson, Karen C and Wilmoth, Sharon and Bahnson, Judy and Dulin, Michael F and Green, Jennifer B and Knowler, William C and Kitabchi, Abbas and Murillo, Anne L and Osei, Kwame and Rehman, Shakaib U and Cushman, William C and Accord Study Grp and Ahead Res Grp and Look AHEAD Research Group and ACCORD Study Group and the Look AHEAD Research Group and the ACCORD Study Group
American Journal of Hypertension, ISSN 0895-7061, 8/2015, Volume 28, Issue 8, pp. 995 - 1009
BACKGROUND The relative effectiveness of 3 approaches to blood pressure control—(i) an intensive lifestyle intervention (ILI) focused on weight loss, (ii)... 
blood pressure | comparative effectiveness | blood pressure control | diabetes | hypertension | lifestyle intervention | obesity | blood pressure monitoring | MANAGEMENT | PERIPHERAL VASCULAR DISEASE | HEALTH | Exercise Therapy - methods | Overweight - complications | Obesity - complications | Humans | Middle Aged | Male | Antihypertensive Agents - therapeutic use | Motor Activity | Overweight - therapy | Diet, Reducing - methods | Obesity - therapy | Hypertension - complications | Diet Therapy - methods | Female | Aged | Hypertension - therapy | Self Care | Diabetes Mellitus, Type 2 - complications | Patient Education as Topic - methods | Type 2 diabetes | Measurement | Care and treatment | Blood pressure | Demographic aspects | Methods | Diabetes | Original
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6. Full Text Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods
by Buse, John B., MD, PhD and ACCORD Study Grp and ACCORD Study Group
American Journal of Cardiology, The, ISSN 0002-9149, 2007, Volume 99, Issue 12, pp. S21 - S33
Most patients with type 2 diabetes mellitus develop cardiovascular disease (CVD), with substantial loss of life expectancy. Nonfatal CVD contributes greatly to... 
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | DISEASE | ADULTS | PREVENTION | MELLITUS | HEALTH | INTERVENTION | STRATEGIES | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Humans | Coronary Artery Disease - prevention & control | Fenofibrate - administration & dosage | Diabetic Angiopathies - blood | Coronary Artery Disease - blood | Fenofibrate - therapeutic use | Patient Selection | Randomized Controlled Trials as Topic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Glycated Hemoglobin A | Hypolipidemic Agents - administration & dosage | Diabetes Mellitus, Type 2 | Hypolipidemic Agents - therapeutic use | Diabetic Angiopathies - prevention & control | Research Design | Obesity | Diabetics | Anticholesteremic agents | Clinical trials | Diabetes | Cardiovascular diseases | Blood lipoproteins | Health aspects | Risk factors | Methods | Diabetes therapy
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7. Full Text Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis
by Tan, Darrell H. S and Hull, Mark W and Yoong, Deborah and Tremblay, Cécile and O'Byrne, Patrick and Thomas, Réjean and Kille, Julie and Baril, Jean-Guy and Cox, Joseph and Giguere, Pierre and Harris, Marianne and Hughes, Christine and MacPherson, Paul and O'Donnell, Shannon and Reimer, Joss and Singh, Ameeta and Barrett, Lisa and Bogoch, Isaac and Jollimore, Jody and Lambert, Gilles and Lebouche, Bertrand and Metz, Gila and Rogers, Tim and Shafran, Stephen and Biomedical HIV Prevention Work
CMAJ, ISSN 0820-3946, 11/2017, Volume 189, Issue 47, pp. E1448 - E1458
New HIV infections occur every year in Canada, highlighting the need for integrated prevention programs. Pre-exposure prophylaxis (PrEP) and nonoccupational... 
UNITED-STATES | DRUG-USERS | MEDICINE, GENERAL & INTERNAL | AFRICAN WOMEN | TRANSMISSION | ANTIRETROVIRAL PROPHYLAXIS | IMMUNODEFICIENCY-VIRUS | PHASE-3 TRIAL | DOUBLE-BLIND | INFECTION | TENOFOVIR | Prevention | Practice guidelines (Medicine) | Evaluation | HIV infection | Antiretroviral drugs | Emergency medical care | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Drug use
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8. Full Text Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with 'refractoriness to treatment': a cohort study
by Henriquez, Dacia D. C. A and Gillissen, Ada and Smith, Sharissa M and Cramer, Roos A and van den Akker, Thomas and Zwart, Joost J and van Roosmalen, Jos J. M and Bloemenkamp, Kitty W. M and van der Bom, Johanna G and Aiaanse, H. J and van den Akker, E. S. A and Bank, C. M. C and van Beek, E and van der Borden, D. M. R and Bremer, H. A and Ceelie, H and Chon, H and Cikot, J. L. M and Delemarre, F. M. C and Diris, J. H. C and Doesburg-van Kleffens, M and van Dooren, I. M. A and van Duijnhoven, J. L. P and van Dunn, F. M and Duvekot, J. J and Engbers, P and van Etten-van Hulst, M. J. W and Feitsma, H and Fouraux, M. A and Franssen, M. T. M and Frasa, M. A. M and van Gammeren, A. J and van Gemund, N and van der Graaf, F and Hackeng, C. M and van der Ham, D. P and Hanssen, M. J. C. P and Hasaart, T. H. M and Henskens, Y. M. C and Hermsen, B. B. J and de Kok, J. B and Koops, A and de Mare, A and Meekers, J. H and Metz, G. C. H and Pouwels, J. G. J and Prinzen, L and Sikkema, J. M and Slomp, J and Visser, O and TeMpOH-1 Study Grp and on behalf of the TeMpOH-1 study group
BMC Pregnancy and Childbirth, ISSN 1471-2393, 10/2019, Volume 19, Issue 1, pp. 1 - 10
Background The absence of a uniform and clinically relevant definition of severe postpartum haemorrhage hampers comparative studies and optimization of... 
Postpartum haemorrhage | Definition | SEVERE MATERNAL MORBIDITY | Maternal morbidity | Maternal mortality | PREVALENCE | OBSTETRICS & GYNECOLOGY | Blood transfusions | Medical research | Placenta | Womens health | Data collection | Obstetrics | Morbidity
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