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1. Full Text Megahertz serial crystallography
by Wiedorn, Max O and Oberthür, Dominik and Bean, Richard and Schubert, Robin and Werner, Nadine and Abbey, Brian and Aepfelbacher, Martin and Adriano, Luigi and Allahgholi, Aschkan and Al-Qudami, Nasser and Andreasson, Jakob and Aplin, Steve and Awel, Salah and Ayyer, Kartik and Bajt, Saša and Barák, Imrich and Bari, Sadia and Bielecki, Johan and Botha, Sabine and Boukhelef, Djelloul and Brehm, Wolfgang and Brockhauser, Sandor and Cheviakov, Igor and Coleman, Matthew A and Cruz-Mazo, Francisco and Danilevski, Cyril and Darmanin, Connie and Doak, R. Bruce and Domaracky, Martin and Dörner, Katerina and Du, Yang and Fangohr, Hans and Fleckenstein, Holger and Frank, Matthias and Fromme, Petra and Gañán-Calvo, Alfonso M and Gevorkov, Yaroslav and Giewekemeyer, Klaus and Ginn, Helen Mary and Graafsma, Heinz and Graceffa, Rita and Greiffenberg, Dominic and Gumprecht, Lars and Göttlicher, Peter and Hajdu, Janos and Hauf, Steffen and Heymann, Michael and Holmes, Susannah and Horke, Daniel A and Hunter, Mark S and Imlau, Siegfried and Kaukher, Alexander and Kim, Yoonhee and Klyuev, Alexander and Knoška, Juraj and Kobe, Bostjan and Kuhn, Manuela and Kupitz, Christopher and Küpper, Jochen and Lahey-Rudolph, Janine Mia and Laurus, Torsten and Le Cong, Karoline and Letrun, Romain and Xavier, P. Lourdu and Maia, Luis and Maia, Filipe R. N. C and Mariani, Valerio and Messerschmidt, Marc and Metz, Markus and Mezza, Davide and Michelat, Thomas and Mills, Grant and Monteiro, Diana C. F and Morgan, Andrew and Mühlig, Kerstin and Munke, Anna and Münnich, Astrid and Nette, Julia and Nugent, Keith A and Nuguid, Theresa and Orville, Allen M and Pandey, Suraj and Pena, Gisel and Villanueva-Perez, Pablo and Poehlsen, Jennifer and Previtali, Gianpietro and Redecke, Lars and Riekehr, Winnie Maria and Rohde, Holger and Round, Adam and Safenreiter, Tatiana and Sarrou, Iosifina and Sato, Tokushi and Schmidt, Marius and Schmitt, Bernd and Schönherr, Robert and Schulz, Joachim and Sellberg, Jonas A and Seibert, M. Marvin and Seuring, Carolin and ... and SLAC National Accelerator Lab., Menlo Park, CA (United States) and BioXFEL
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4025 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Femtosecond | X ray lasers | Antibiotics | Lasers | Antibiotic resistance | Crystallography | Lysozyme | Substrates | Repetition | CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS | MATERIALS SCIENCE
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2. Full Text Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors
by Strosberg, Jonathan and El-Haddad, Ghassan and Wolin, Edward and Hendifar, Andrew and Yao, James and Chasen, Beth and Mittra, Erik and Kunz, Pamela L and Kulke, Matthew H and Jacene, Heather and Bushnell, David and O’Dorisio, Thomas M and Baum, Richard P and Kulkarni, Harshad R and Caplin, Martyn and Lebtahi, Rachida and Hobday, Timothy and Delpassand, Ebrahim and Van Cutsem, Eric and Benson, Al and Srirajaskanthan, Rajaventhan and Pavel, Marianne and Mora, Jaime and Berlin, Jordan and Grande, Enrique and Reed, Nicholas and Seregni, Ettore and Öberg, Kjell and Lopera Sierra, Maribel and Santoro, Paola and Thevenet, Thomas and Erion, Jack L and Ruszniewski, Philippe and Kwekkeboom, Dik and Krenning, Eric
The New England journal of medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 2, pp. 125 - 135
Thrombocytopenia | Intravenous administration | Midgut | Clinical trials | Octreotide | Metastasis | Cancer therapies | Survival | Patients | Metastases | Lymphopenia | Myelosuppression | Somatostatin | Cancer | Neutropenia | Neuroendocrine tumors | Tumors | Index Medicus | Abridged Index Medicus
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3. Full Text Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
by Wang, Mingxun and Carver, Jeremy J and Phelan, Vanessa V and Sanchez, Laura M and Garg, Neha and Peng, Yao and Nguyen, Don Duy and Watrous, Jeramie and Kapono, Clifford A and Luzzatto-Knaan, Tal and Porto, Carla and Bouslimani, Amina and Melnik, Alexey V and Meehan, Michael J and Liu, Wei-Ting and Crüsemann, Max and Boudreau, Paul D and Esquenazi, Eduardo and Sandoval-Calderón, Mario and Kersten, Roland D and Pace, Laura A and Quinn, Robert A and Duncan, Katherine R and Hsu, Cheng-Chih and Floros, Dimitrios J and Gavilan, Ronnie G and Kleigrewe, Karin and Northen, Trent and Dutton, Rachel J and Parrot, Delphine and Carlson, Erin E and Aigle, Bertrand and Michelsen, Charlotte F and Jelsbak, Lars and Sohlenkamp, Christian and Pevzner, Pavel and Edlund, Anna and McLean, Jeffrey and Piel, Jörn and Murphy, Brian T and Gerwick, Lena and Liaw, Chih-Chuang and Yang, Yu-Liang and Humpf, Hans-Ulrich and Maansson, Maria and Keyzers, Robert A and Sims, Amy C and Johnson, Andrew R and Sidebottom, Ashley M and Sedio, Brian E and Klitgaard, Andreas and Larson, Charles B and Boya, Cristopher A.P and Torres-Mendoza, Daniel and Gonzalez, David J and Silva, Denise B and Marques, Lucas M and Demarque, Daniel P and Pociute, Egle and O'Neill, Ellis C and Briand, Enora and Helfrich, Eric J. N and Granatosky, Eve A and Glukhov, Evgenia and Ryffel, Florian and Houson, Hailey and Mohimani, Hosein and Kharbush, Jenan J and Zeng, Yi and Vorholt, Julia A and Kurita, Kenji L and Charusanti, Pep and McPhail, Kerry L and Nielsen, Kristian Fog and Vuong, Lisa and Elfeki, Maryam and Traxler, Matthew F and Engene, Niclas and Koyama, Nobuhiro and Vining, Oliver B and Baric, Ralph and Silva, Ricardo R and Mascuch, Samantha J and Tomasi, Sophie and Jenkins, Stefan and Macherla, Venkat and Hoffman, Thomas and Agarwal, Vinayak and Williams, Philip G and Dai, Jingqui and Neupane, Ram and Gurr, Joshua and Rodríguez, Andrés M. C and Lamsa, Anne and Zhang, Chen and Dorrestein, Kathleen and Duggan, Brendan M and Almaliti, Jehad and Allard, Pierre-Marie and Phapale, Prasad and ...
Nature biotechnology, ISSN 1087-0156, 09/2016, Volume 34, Issue 8, pp. 828 - 837
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Mass Spectrometry - statistics & numerical data | Biological Products - chemistry | Biological Products - classification | Information Storage and Retrieval - methods | Databases, Chemical | Internationality | Database Management Systems | Information Dissemination - methods | Data Curation - methods | Electronic data processing | Natural products | Chemical research | Molecular dynamics | Research | Chemical properties | Mass spectrometry | Methods | Biotechnology | Index Medicus | Life Sciences | Ecology, environment
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4. Full Text Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets
by Thierry Alquier and Marie-Line Peyot and Martin G. Latour and Melkam Kebede and Christina M. Sorensen and Stephane Gesta and C. Ronald Kahn and Richard D. Smith and Thomas L. Jetton and Thomas O. Metz and Marc Prentki and Vincent Poitout and Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
Diabetes (New York, N.Y.), ISSN 0012-1797, 11/2009, Volume 58, Issue 11, pp. 2607 - 2615
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Islets of Langerhans - drug effects | Arachidonic Acid - metabolism | Lipids - physiology | Mice, Inbred C57BL | Gene Expression Profiling | Glucose - pharmacology | Mice, Knockout | Lipids - isolation & purification | Insulin - metabolism | Animals | Receptors, G-Protein-Coupled - deficiency | Islets of Langerhans - metabolism | Arginine - pharmacology | Islets of Langerhans - cytology | Insulin-Secreting Cells - cytology | Mice | Receptors, G-Protein-Coupled - genetics | Inositol Phosphates - metabolism | Fatty Acids - metabolism | Insulin Secretion | Adipose Tissue - anatomy & histology | Fatty Acids - pharmacology | Glucose metabolism | Cell receptors | Pancreatic beta cells | Physiological aspects | Genetic aspects | Research | G proteins | Gene expression | Index Medicus | Abridged Index Medicus | BASIC BIOLOGICAL SCIENCES | SENSITIVITY | TRIGLYCERIDES | IN VIVO | INSULIN | METABOLISM | GLUCOSE | Environmental Molecular Sciences Laboratory | ARGININE | CARBOXYLIC ACIDS | MICE | SECRETION | LIPIDS | Original
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5. Full Text Leucine biosynthesis is involved in regulating high lipid accumulation in Yarrowia lipolytica
by Kerkhoven, Eduard J and Kim, Young-Mo and Wei, Siwei and Nicora, Carrie D and Fillmore, Thomas L and Purvine, Samuel O and Webb-Robertson, Bobbie-Jo and Smith, Richard D and Baker, Scott E and Metz, Thomas O and Nielsena, Jens and Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
mBio, ISSN 2161-2129, 05/2017, Volume 8, Issue 3, p. e00857-17
Biotechnology | Metabolic engineering | Yeast | Biofuels | Systems biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Gene Expression Regulation, Fungal | Carbon - metabolism | Nitrogen - metabolism | Yarrowia - metabolism | Diacylglycerol O-Acyltransferase - genetics | Leucine - biosynthesis | Diacylglycerol O-Acyltransferase - metabolism | Lipogenesis | Yarrowia - genetics | Index Medicus | systems biology | biotechnology | BASIC BIOLOGICAL SCIENCES | Environmental Molecular Sciences Laboratory | biofuels | metabolic engineering | yeast
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6. Full Text Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein
by Pande, Kanupriya and Hutchison, Christopher D.M and Groenhof, Gerrit and Aquila, Andy and Robinson, Josef S and Tenboer, Jason and Basu, Shibom and Boutet, Sébastien and DePonte, Daniel P and Liang, Mengning and White, Thomas A and Zatsepin, Nadia A and Yefanov, Oleksandr and Morozov, Dmitry and Oberthuer, Dominik and Gati, Cornelius and Subramanian, Ganesh and James, Daniel and Zhao, Yun and Koralek, Jake and Brayshaw, Jennifer and Kupitz, Christopher and Conrad, Chelsie and Roy-Chowdhury, Shatabdi and Coe, Jesse D and Metz, Markus and Xavier, Paulraj Lourdu and Grant, Thomas D and Koglin, Jason E and Ketawala, Gihan and Fromme, Raimund and Srajer, Vukica and Henning, Robert and Spence, John C and Ourmazd, Abbas and Schwander, Peter and Weierstall, Uwe and Frank, Matthias and Fromme, Petra and Barty, Anton and Chapman, Henry N and Moffat, Keith and Van Thor, Jasper J and Schmidt, Marius and SLAC National Accelerator Lab., Menlo Park, CA (United States)
Science (American Association for the Advancement of Science), ISSN 0036-8075, 05/2016, Volume 352, Issue 6286, pp. 725 - 729
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Photoreceptors, Microbial - chemistry | Protein Conformation - radiation effects | Time Factors | Light | Bacterial Proteins - chemistry | Bacterial Proteins - radiation effects | Photons | Crystallography | Isomerism | Photoreceptors, Microbial - radiation effects | Photochemical Processes | Isomerization | Proteins | Physiological aspects | Chromophores | Observations | Structure | Photochemistry | Index Medicus
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7. Full Text Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts
by Frésard, Laure and Smail, Craig and Ferraro, Nicole M and Teran, Nicole A and Li, Xin and Smith, Kevin S and Bonner, Devon and Kernohan, Kristin D and Marwaha, Shruti and Zappala, Zachary and Balliu, Brunilda and Davis, Joe R and Liu, Boxiang and Prybol, Cameron J and Kohler, Jennefer N and Zastrow, Diane B and Reuter, Chloe M and Fisk, Dianna G and Grove, Megan E and Davidson, Jean M and Hartley, Taila and Joshi, Ruchi and Strober, Benjamin J and Utiramerur, Sowmithri and Adams, David R and Aday, Aaron and Alejandro, Mercedes E and Allard, Patrick and Ashley, Euan A and Azamian, Mahshid S and Bacino, Carlos A and Baker, Eva and Balasubramanyam, Ashok and Barseghyan, Hayk and Batzli, Gabriel F and Beggs, Alan H and Behnam, Babak and Bellen, Hugo J and Bernstein, Jonathan A and Berry, Gerard T and Bican, Anna and Bick, David P and Birch, Camille L and Bonner, Devon and Boone, Braden E and Bostwick, Bret L and Briere, Lauren C and Brokamp, Elly and Brown, Donna M and Brush, Matthew and Burke, Elizabeth A and Burrage, Lindsay C and Butte, Manish J and Chen, Shan and Clark, Gary D and Coakley, Terra R and Cogan, Joy D and Colley, Heather A and Cooper, Cynthia M and Cope, Heidi and Craigen, William J and D’Souza, Precilla and Davids, Mariska and Davidson, Jean M and Dayal, Jyoti G and Dell’Angelica, Esteban C and Dhar, Shweta U and Dipple, Katrina M and Donnell-Fink, Laurel A and Dorrani, Naghmeh and Dorset, Daniel C and Douine, Emilie D and Draper, David D and Dries, Annika M and Duncan, Laura and Eckstein, David J and Emrick, Lisa T and Eng, Christine M and Enns, Gregory M and Eskin, Ascia and Esteves, Cecilia and Estwick, Tyra and Fernandez, Liliana and Ferreira, Carlos and Fieg, Elizabeth L and Fisher, Paul G and Fogel, Brent L and Friedman, Noah D and Gahl, William A and Glanton, Emily and Godfrey, Rena A and Goldman, Alica M and Goldstein, David B and Gould, Sarah E and Gourdine, Jean-Philippe F and Groden, Catherine A and Gropman, Andrea L and Haendel, Melissa and Hamid, Rizwan and Hanchard, Neil A and ... and Care4Rare Canada Consortium and Undiagnosed Dis Network and Undiagnosed Diseases Network
Nature medicine, ISSN 1078-8956, 06/2019, Volume 25, Issue 6, pp. 911 - 919
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Rare Diseases - genetics | Acid Ceramidase - genetics | Rare Diseases - blood | Humans | Child, Preschool | Male | Case-Control Studies | Potassium Channels - genetics | RNA - genetics | Whole Exome Sequencing | Genetic Variation | Sequence Analysis, RNA | RNA Splicing - genetics | Female | Oxidoreductases Acting on CH-CH Group Donors - genetics | Models, Genetic | Mutation | Child | RNA - blood | Cohort Studies | Disease | Splicing | Muscles | Ribonucleic acid--RNA | Gene expression | Disease control | Blood | Gene sequencing | Diseases | Mitochondria | Biopsy | Diagnostic software | Fibroblasts | Diagnostic systems | Index Medicus
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