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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Index Medicus | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
by Kilpeläinen, Tuomas O and Carli, Jayne F. Martin and Skowronski, Alicja A and Sun, Qi and Kriebel, Jennifer and Feitosa, Mary F and Hedman, Åsa K and ng, Alexander W and Hayes, James E and Zhao, Jinghua and Pers, Tune H and Schick, Ursula and Grarup, Niels and Kutalik, Zoltán and Trompet, Stella and Mangino, Massimo and Kristiansson, Kati and Beekman, Marian and Lyytikäinen, Leo-Pekka and Eriksson, Joel and Henneman, Peter and Lahti, Jari and Tanaka, Toshiko and Luan, Jian'an and del Greco M, Fabiola and Pasko, Dorota and Renström, Frida and Willems, Sara M and Mahajan, Anubha and Rose, Lynda M and Guo, Xiuqing and Liu, Yongmei and Kleber, Marcus E and Pérusse, Louis and Gaunt, Tom and Ahluwalia, Tarunveer S and Ju Sung, Yun and Ramos, Yolande F and Amin, Najaf and Amuzu, Antoinette and Barroso, Inês and Bellis, Claire and Blangero, John and Buckley, Brendan M and Böhringer, Stefan and I Chen, Yii-Der and de Craen, Anton J. N and Crosslin, David R and Dale, Caroline E and Dastani, Zari and Day, Felix R and Deelen, Joris and Delgado, Graciela E and Demirkan, Ayse and Finucane, Francis M and Ford, Ian and Garcia, Melissa E and Gieger, Christian and Gustafsson, Stefan and Hallmans, Göran and Hankinson, Susan E and Havulinna, Aki S and Herder, Christian and Hernandez, Dena and Hicks, Anew A and Hunter, David J and Illig, Thomas and Ingelsson, Erik and Ioan-Facsinay, Aneea and Jansson, John-Olov and Jenny, Nancy S and Jørgensen, Marit E and Jørgensen, Torben and Karlsson, Magnus and Koenig, Wolfgang and Kraft, Peter and Kwekkeboom, Joanneke and Laatikainen, Tiina and Ladwig, Karl-Heinz and LeDuc, Charles A and Lowe, Gordon and Lu, Yingchang and Marques-Vidal, Peo and Meisinger, Christa and Menni, Cristina and Morris, Anew P and Myers, Richard H and Männistö, Satu and Nalls, Mike A and Paternoster, Lavinia and Peters, Annette and Pradhan, Aruna D and Rankinen, Tuomo and Rasmussen-Torvik, Laura J and Rathmann, Wolfgang and Rice, Treva K and Brent Richards, J and Ridker, Paul M and Sattar, Naveed and Savage, David B and ... and Medicinska fakulteten and Kardiologi and Umeå universitet and Medicin and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Näringsforskning
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, pp. 10494 - 10494
Journal Article
by Dastani, Zari and Hivert, Marie-France and Timpson, Nicholas and Perry, John R. B and Yuan, Xin and Scott, Robert A and Henneman, Peter and Heid, Iris M and Kizer, Jorge R and Lyytikäinen, Leo-Pekka and Fuchsberger, Christian and Tanaka, Toshiko and Morris, Anew P and Small, Kerrin and Isaacs, Aaron and Beekman, Marian and Coassin, Stefan and Lohman, Kurt and Qi, Lu and Kanoni, Stavroula and Pankow, James S and Uh, Hae-Won and Wu, Ying and Bidulescu, Aurelian and Rasmussen-Torvik, Laura J and Greenwood, Celia M. T and Ladouceur, Martin and Grimsby, Jonna and Manning, Alisa K and Liu, Ching-Ti and Kooner, Jaspal and Mooser, Vincent E and Vollenweider, Peter and Kapur, Karen A and Chambers, John and Wareham, Nicholas J and Langenberg, Claudia and Frants, Rune and Willems-Vandijk, Ko and Oostra, Ben A and Willems, Sara M and Lamina, Claudia and Winkler, Thomas W and Psaty, Bruce M and Tracy, Russell P and Brody, Jennifer and Chen, Ida and Viikari, Jorma and Kähönen, Mika and Pramstaller, Peter P and Evans, David M and St Pourcain, Beate and Sattar, Naveed and Wood, Anew R and Bandinelli, Stefania and Carlson, Olga D and Egan, Josephine M and Böhringer, Stefan and van Heemst, Diana and Kedenko, Lyudmyla and Kristiansson, Kati and Nuotio, Marja-Liisa and Loo, Britt-Marie and Harris, Tamara and Garcia, Melissa and Kanaya, Alka and Haun, Margot and Klopp, Norman and Wichmann, H.-Erich and Deloukas, Panos and Katsareli, Efi and Couper, David J and Duncan, Bruce B and Kloppenburg, Margreet and Adair, Linda S and Borja, Judith B and Wilson, James G and Musani, Solomon and Guo, Xiuqing and Johnson, Toby and Semple, Robert and Teslovich, Tanya M and Allison, Matthew A and Redline, Susan and Buxbaum, Sarah G and Mohlke, Karen L and Meulenbelt, Ingrid and Ballantyne, Christie M and Dedoussis, George V and Hu, Frank B and Liu, Yongmei and Paulweber, Bernhard and Spector, Timothy D and Slagboom, P. Eline and Ferrucci, Luigi and Jula, Antti and Perola, Markus and Raitakari, Olli and Florez, Jose C and Salomaa, Veikko and ... and GLGC Investigators and DIAGRAM Consortium and MAGIC Consortium and MuTHER Consortium and Global B Pgen Consortium and MAGIC investigators and Procardis Consortium and DIAGRAM+ Consortium and GLGC Consortium and GIANT Consortium
PLoS genetics, ISSN 1553-7390, 2012, Volume 8, Issue 3, pp. e1002607 - e1002607
Journal Article
by Peters, Marjolein and Joehanes, Roby and Pilling, Luke and Schurmann, Claudia and Conneely, Karen N and Powell, Joseph and Reinmaa, Eva and Sutphin, George L and Zhernakova, Alexana and Schramm, Katharina and Wilson, Yana A and Kobes, Sayuko and Tukiainen, Taru and Ramos, Yolande and Göring, Harald H and Fornage, Myriam and Liu, Yongmei and Gharib, Sina and Stranger, Barbara and Jager, Philip and Aviv, Abraham and Levy, Daniel and Murabito, Joanne and Munson, Peter J and Huan, Tianxiao and Hofman, Albert and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and van Rooij, Jeroen and Stolk, Lisette and Broer, Linda and Verbiest, Michael and Jhamai, Mila and Arp, Pascal and Metspalu, Anes and Tserel, Liina and Milani, Lili and Samani, Nilesh and Peterson, Pärt and Kasela, Silva and Codd, Veryan and Peters, Annette and Ward-Caviness, Cavin K and Herder, Christian and Waldenberger, Melanie and Roden, Michael and Singmann, Paula and Zeilinger, Sonja and Illig, Thomas and Homuth, Georg and Grabe, Hans Jörgen and Völzke, Henry and Steil, Leif and Kocher, Thomas and Murray, Anna and Melzer, David and Yaghootkar, Hanieh and Bandinelli, S and Moses, Eric and Kent, Jack and Curran, Joanne and Johnson, Matthew and Williams-Blangero, Sarah and Westra, Harm-Jan and McRae, Allan F and Smith, Jennifer A and Kardia, Sharon and Hovatta, Iiris and Perola, Markus and Ripatti, Samuli and Salomaa, Veikko and Henders, Anjali and Martin, Nicholas and Smith, Alicia K and Mehta, Divya and Binder, Elisabeth B and Nylocks, K. Maria and Kennedy, Elizabeth M and Klengel, Torsten and Ding, Jingzhong and Suchy-Dicey, Astrid and Enquobahrie, D and Brody, Jennifer and Rotter, Jerome I and Chen, Yii-Der I and Houwing-Duistermaat, Jeanine and Kloppenburg, Margreet and Slagboom, Eline and Helmer, Quinta and Hollander, Wouter and Bean, Shannon and Raj, Towfique and Bakhshi, Noman and Wang, Qiao Ping and Oyston, Lisa J and Psaty, Bruce and Tracy, Russell and Montgomery, Grant and Turner, Stephen and Blangero, John and ... and NABEC UKBEC Consortium and NABEC/UKBEC Consortium
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, pp. 8570 - 8570
textabstractDisease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately... 
LIFE-SPAN | OXIDATIVE STRESS | METHYLATION | PROFILES | GLYCOSAMINOGLYCANS | HUMAN LONGEVITY | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | PATTERNS | GENE-EXPRESSION CHANGES | GENOME-WIDE ASSOCIATION | Aging - blood | DNA Methylation | Humans | Transcriptome | European Continental Ancestry Group | Gene Expression Profiling | Biomarkers - blood | Index Medicus
Journal Article
Current Genomics, ISSN 1389-2029, 09/2015, Volume 16, Issue 6, pp. 419 - 426
Osteoarthritis (OA) is a prevalent disease of articular joints and primarily characterized by degradation and calcification of articular cartilage. Presently,... 
DNA methylation | Articular cartilage | Transcriptomics | Osteoarthritis | Data integration | RADIOGRAPHIC SUBTYPES | CHONDROCYTES | BIOCHEMICAL MARKERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GDF5 | ALLELIC EXPRESSION | MULTIPLE SITES | ARTICULAR-CARTILAGE | CPG SITES | GENETICS & HEREDITY | GENE-EXPRESSION | FUNCTIONAL-ANALYSIS
Journal Article